| Definition | Bradyrhizobium sp. ORS278 chromosome, complete genome. |
|---|---|
| Accession | NC_009445 |
| Length | 7,456,587 |
Click here to switch to the map view.
The map label for this gene is fadD [H]
Identifier: 146343338
GI number: 146343338
Start: 6812318
End: 6813826
Strand: Direct
Name: fadD [H]
Synonym: BRADO6564
Alternate gene names: 146343338
Gene position: 6812318-6813826 (Clockwise)
Preceding gene: 146343333
Following gene: 146343340
Centisome position: 91.36
GC content: 67.53
Gene sequence:
>1509_bases TTGTCGCGCCATCCGCAGCGCACCGCTTTCAGCTGGCCGGGAGGATCGCTGTCCTATCAGGGCGCGATCGACTTGATCGG CCGCATGCAGGGCGTGTTCATGCGGCTCGGCCTGCCGCCTGGAACACGCGTCGCGTTCCTCACCGCGAATCGCGCCGATG CGTGGTGCGCCGGCATGGCGGCGCAGCTGTCGCGGCTCGCCATCACCTGGCTGCATCCGCTGGGCTCGCTGGAGGACCAG CTGTTCCAGCTGTCGGATTCCGAGTCGCAGGTGCTGGTGATCGATGCCGCCGCGTTCCGCGACCGCGGCGGTGAACTCGC CGCGCGCGCCGACGGTCTGCGCCATGTGTTCACGCTCGGGCCCGCCGGGTACGGCGCCGATCTGCTCGCCGCCATCGCGC AATCCGGCCACGCCACCGCGCGCAATTTCGCGAGACCCGACGACCTCGCCACGCTCAACTACACCGGCGGCACCACGGGC AAGTCGAAGGGCGCGCTGCGCCATCACCGGGAATATGGCGGCTTCGCCACGGCGATCCTCGCCGATTTCGAGATTCCGGA CCGCGCCCGATATCTCACGGTGGCGCCGATCAGCCACGTCGCCGGCACCAAGGTGCTGCCGACCCTGATGCGCGGCGGCA CCGTGCACATGCTCAAAGGGTTTGATCCCGAGGCCGTGCTGGACACCATCGCCCGCGAGCGCATCAACTTCACTCTGTTC GTACCGACCATGATCTACGTGCTGCTCGATCATCCCGCGCTCGCCAGGACCGATCTCTCCTCGCTGGAGCTCGTGCTCTA CGGCGCGTCCGCGATGTCGCCGACACGGCTGGTCGAAGGCATCGAGCGTATCGGCCCGGTGTTCTCGCAGCTCTACGGCC AGACCGAATGCTATCCGGTGTCGGTGCTGCGCAAGGCCGATCATGATCCGAAGCAGCCGGAGCTGTTTCTGTCGTGCGGC TTCCCGATCGCGGCTTGCGAGGTCAAGATCCTCGACGACGATGATCAGGAGGCGCCGCAGGGCGAGGCTGGCGAGATCTG CGTGCGCGCGCCGCATGTGATGGCGGAATACTGGAAACGGCCCGACATCACGGCGGAGACCCTGAAGAACGGCTGGCTGC GCACCGGCGACATCGCGCGCCGCGACGAGCGCGGCTACCTGTACATCCTCGATCGCAAGAAGGACATGATCGTCTCCGGC GGCTTCAACATCTTTCCGCGCGAGATCGAGGACGTGCTGACGCAGCACGCCGATGTCGCGATGTGCGCCGTGGTCGGCGT GCCCGACGACAAATGGGGCGAGGCCGTCACCGCGATCGTAGTGCCGCGCGCGGGCGCGCAGCCCAACGCGACCGAGCTGA TCGAGCTGGTCAAGGCGCGCAAGGGCTCGGCGCACGCGCCGAAGCGCGTCGAGTTCGTCAAGGAGCTGCCGGTGACCGGC GTCGGCAAGATTGACAAGAAGGTGCTGCGCGCGAAGTACTGGGAGGGACGCGGCCGGATGGTGGGATAG
Upstream 100 bases:
>100_bases GCTCCGCGACGCAACAACCAGCGGGGCACTTCGGGAGGACATCCGCATGAACCGTGAACTCCACGCGTTCCCCGTCGTCT GCGAGCAGACGTTGCTTACG
Downstream 100 bases:
>100_bases CGCCACCACGGGGCTTCGGTCTTCTGCGTCATTGCGTCCCTCACCACCGTCGTCCCGGACAAGCTGCGACGCGCGCCGGC GCGGCGCCGATCCGGGTTCC
Product: acyl-CoA synthetase
Products: NA
Alternate protein names: Long-chain acyl-CoA synthetase; Acyl-CoA synthetase [H]
Number of amino acids: Translated: 502; Mature: 501
Protein sequence:
>502_residues MSRHPQRTAFSWPGGSLSYQGAIDLIGRMQGVFMRLGLPPGTRVAFLTANRADAWCAGMAAQLSRLAITWLHPLGSLEDQ LFQLSDSESQVLVIDAAAFRDRGGELAARADGLRHVFTLGPAGYGADLLAAIAQSGHATARNFARPDDLATLNYTGGTTG KSKGALRHHREYGGFATAILADFEIPDRARYLTVAPISHVAGTKVLPTLMRGGTVHMLKGFDPEAVLDTIARERINFTLF VPTMIYVLLDHPALARTDLSSLELVLYGASAMSPTRLVEGIERIGPVFSQLYGQTECYPVSVLRKADHDPKQPELFLSCG FPIAACEVKILDDDDQEAPQGEAGEICVRAPHVMAEYWKRPDITAETLKNGWLRTGDIARRDERGYLYILDRKKDMIVSG GFNIFPREIEDVLTQHADVAMCAVVGVPDDKWGEAVTAIVVPRAGAQPNATELIELVKARKGSAHAPKRVEFVKELPVTG VGKIDKKVLRAKYWEGRGRMVG
Sequences:
>Translated_502_residues MSRHPQRTAFSWPGGSLSYQGAIDLIGRMQGVFMRLGLPPGTRVAFLTANRADAWCAGMAAQLSRLAITWLHPLGSLEDQ LFQLSDSESQVLVIDAAAFRDRGGELAARADGLRHVFTLGPAGYGADLLAAIAQSGHATARNFARPDDLATLNYTGGTTG KSKGALRHHREYGGFATAILADFEIPDRARYLTVAPISHVAGTKVLPTLMRGGTVHMLKGFDPEAVLDTIARERINFTLF VPTMIYVLLDHPALARTDLSSLELVLYGASAMSPTRLVEGIERIGPVFSQLYGQTECYPVSVLRKADHDPKQPELFLSCG FPIAACEVKILDDDDQEAPQGEAGEICVRAPHVMAEYWKRPDITAETLKNGWLRTGDIARRDERGYLYILDRKKDMIVSG GFNIFPREIEDVLTQHADVAMCAVVGVPDDKWGEAVTAIVVPRAGAQPNATELIELVKARKGSAHAPKRVEFVKELPVTG VGKIDKKVLRAKYWEGRGRMVG >Mature_501_residues SRHPQRTAFSWPGGSLSYQGAIDLIGRMQGVFMRLGLPPGTRVAFLTANRADAWCAGMAAQLSRLAITWLHPLGSLEDQL FQLSDSESQVLVIDAAAFRDRGGELAARADGLRHVFTLGPAGYGADLLAAIAQSGHATARNFARPDDLATLNYTGGTTGK SKGALRHHREYGGFATAILADFEIPDRARYLTVAPISHVAGTKVLPTLMRGGTVHMLKGFDPEAVLDTIARERINFTLFV PTMIYVLLDHPALARTDLSSLELVLYGASAMSPTRLVEGIERIGPVFSQLYGQTECYPVSVLRKADHDPKQPELFLSCGF PIAACEVKILDDDDQEAPQGEAGEICVRAPHVMAEYWKRPDITAETLKNGWLRTGDIARRDERGYLYILDRKKDMIVSGG FNIFPREIEDVLTQHADVAMCAVVGVPDDKWGEAVTAIVVPRAGAQPNATELIELVKARKGSAHAPKRVEFVKELPVTGV GKIDKKVLRAKYWEGRGRMVG
Specific function: Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Membrane; Peripheral membrane protein (Potential). Note=Partially membrane-associated (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI156151445, Length=362, Percent_Identity=29.8342541436464, Blast_Score=152, Evalue=6e-37, Organism=Homo sapiens, GI187761345, Length=492, Percent_Identity=27.4390243902439, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI187761343, Length=492, Percent_Identity=27.4390243902439, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI42544132, Length=518, Percent_Identity=24.5173745173745, Blast_Score=127, Evalue=3e-29, Organism=Homo sapiens, GI38505220, Length=479, Percent_Identity=27.7661795407098, Blast_Score=126, Evalue=4e-29, Organism=Homo sapiens, GI122937307, Length=270, Percent_Identity=32.962962962963, Blast_Score=122, Evalue=6e-28, Organism=Homo sapiens, GI157311624, Length=298, Percent_Identity=29.1946308724832, Blast_Score=120, Evalue=4e-27, Organism=Homo sapiens, GI157311622, Length=298, Percent_Identity=29.1946308724832, Blast_Score=120, Evalue=4e-27, Organism=Homo sapiens, GI115511026, Length=516, Percent_Identity=26.1627906976744, Blast_Score=119, Evalue=6e-27, Organism=Homo sapiens, GI58082049, Length=298, Percent_Identity=29.1946308724832, Blast_Score=114, Evalue=2e-25, Organism=Homo sapiens, GI40807491, Length=353, Percent_Identity=28.0453257790368, Blast_Score=89, Evalue=9e-18, Organism=Homo sapiens, GI57165410, Length=357, Percent_Identity=26.6106442577031, Blast_Score=86, Evalue=1e-16, Organism=Homo sapiens, GI57165412, Length=359, Percent_Identity=27.0194986072423, Blast_Score=82, Evalue=2e-15, Organism=Homo sapiens, GI42794760, Length=393, Percent_Identity=24.6819338422392, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI42794758, Length=393, Percent_Identity=24.6819338422392, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI42794756, Length=394, Percent_Identity=24.8730964467005, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI13375727, Length=188, Percent_Identity=32.9787234042553, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI28416953, Length=545, Percent_Identity=23.6697247706422, Blast_Score=70, Evalue=6e-12, Organism=Homo sapiens, GI8923896, Length=385, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=7e-11, Organism=Homo sapiens, GI253970489, Length=385, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=9e-11, Organism=Escherichia coli, GI1788107, Length=499, Percent_Identity=32.6653306613226, Blast_Score=229, Evalue=4e-61, Organism=Escherichia coli, GI145693145, Length=377, Percent_Identity=31.2997347480106, Blast_Score=166, Evalue=4e-42, Organism=Escherichia coli, GI221142682, Length=498, Percent_Identity=27.1084337349398, Blast_Score=145, Evalue=8e-36, Organism=Escherichia coli, GI1786810, Length=355, Percent_Identity=30.1408450704225, Blast_Score=135, Evalue=6e-33, Organism=Escherichia coli, GI1790505, Length=550, Percent_Identity=24.1818181818182, Blast_Score=88, Evalue=1e-18, Organism=Escherichia coli, GI1788595, Length=348, Percent_Identity=25.2873563218391, Blast_Score=82, Evalue=7e-17, Organism=Escherichia coli, GI1786529, Length=406, Percent_Identity=27.3399014778325, Blast_Score=82, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17559526, Length=361, Percent_Identity=34.3490304709141, Blast_Score=174, Evalue=7e-44, Organism=Caenorhabditis elegans, GI17558820, Length=359, Percent_Identity=30.9192200557103, Blast_Score=156, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17557194, Length=508, Percent_Identity=26.1811023622047, Blast_Score=147, Evalue=9e-36, Organism=Caenorhabditis elegans, GI17531443, Length=505, Percent_Identity=25.9405940594059, Blast_Score=147, Evalue=1e-35, Organism=Caenorhabditis elegans, GI71994703, Length=361, Percent_Identity=32.409972299169, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI71994694, Length=361, Percent_Identity=32.409972299169, Blast_Score=146, Evalue=2e-35, Organism=Caenorhabditis elegans, GI71994690, Length=361, Percent_Identity=32.409972299169, Blast_Score=146, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17538037, Length=515, Percent_Identity=26.6019417475728, Blast_Score=144, Evalue=9e-35, Organism=Caenorhabditis elegans, GI32563687, Length=379, Percent_Identity=30.0791556728232, Blast_Score=143, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17560308, Length=396, Percent_Identity=31.5656565656566, Blast_Score=135, Evalue=4e-32, Organism=Caenorhabditis elegans, GI17560140, Length=356, Percent_Identity=29.2134831460674, Blast_Score=127, Evalue=2e-29, Organism=Caenorhabditis elegans, GI71996755, Length=375, Percent_Identity=28.8, Blast_Score=113, Evalue=2e-25, Organism=Caenorhabditis elegans, GI71985884, Length=350, Percent_Identity=27.4285714285714, Blast_Score=108, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17510401, Length=517, Percent_Identity=23.9845261121857, Blast_Score=92, Evalue=6e-19, Organism=Caenorhabditis elegans, GI25141359, Length=500, Percent_Identity=22.6, Blast_Score=87, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17556552, Length=482, Percent_Identity=24.0663900414938, Blast_Score=77, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17564090, Length=506, Percent_Identity=21.5415019762846, Blast_Score=75, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6319699, Length=351, Percent_Identity=27.9202279202279, Blast_Score=137, Evalue=5e-33, Organism=Saccharomyces cerevisiae, GI6323182, Length=378, Percent_Identity=27.5132275132275, Blast_Score=81, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6319264, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=1e-15, Organism=Drosophila melanogaster, GI18859661, Length=473, Percent_Identity=28.7526427061311, Blast_Score=155, Evalue=6e-38, Organism=Drosophila melanogaster, GI21355181, Length=498, Percent_Identity=27.3092369477912, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI24581924, Length=350, Percent_Identity=29.7142857142857, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI24653035, Length=279, Percent_Identity=28.673835125448, Blast_Score=116, Evalue=4e-26, Organism=Drosophila melanogaster, GI281365686, Length=243, Percent_Identity=29.6296296296296, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI21356441, Length=286, Percent_Identity=26.9230769230769, Blast_Score=108, Evalue=7e-24, Organism=Drosophila melanogaster, GI24648257, Length=302, Percent_Identity=28.1456953642384, Blast_Score=107, Evalue=2e-23, Organism=Drosophila melanogaster, GI24648260, Length=364, Percent_Identity=27.7472527472527, Blast_Score=107, Evalue=2e-23, Organism=Drosophila melanogaster, GI161076582, Length=296, Percent_Identity=26.3513513513513, Blast_Score=107, Evalue=2e-23, Organism=Drosophila melanogaster, GI21358303, Length=249, Percent_Identity=28.5140562248996, Blast_Score=105, Evalue=6e-23, Organism=Drosophila melanogaster, GI21356947, Length=277, Percent_Identity=28.8808664259928, Blast_Score=105, Evalue=1e-22, Organism=Drosophila melanogaster, GI24648253, Length=287, Percent_Identity=25.0871080139373, Blast_Score=104, Evalue=2e-22, Organism=Drosophila melanogaster, GI24648255, Length=287, Percent_Identity=25.4355400696864, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI19922652, Length=500, Percent_Identity=24.8, Blast_Score=102, Evalue=6e-22, Organism=Drosophila melanogaster, GI20130357, Length=352, Percent_Identity=24.4318181818182, Blast_Score=102, Evalue=7e-22, Organism=Drosophila melanogaster, GI24656500, Length=493, Percent_Identity=26.369168356998, Blast_Score=92, Evalue=6e-19, Organism=Drosophila melanogaster, GI21355225, Length=182, Percent_Identity=30.2197802197802, Blast_Score=79, Evalue=5e-15, Organism=Drosophila melanogaster, GI24667959, Length=367, Percent_Identity=26.7029972752044, Blast_Score=79, Evalue=5e-15, Organism=Drosophila melanogaster, GI62472339, Length=365, Percent_Identity=26.5753424657534, Blast_Score=79, Evalue=6e-15, Organism=Drosophila melanogaster, GI24667955, Length=367, Percent_Identity=26.7029972752044, Blast_Score=79, Evalue=6e-15, Organism=Drosophila melanogaster, GI281366413, Length=186, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-14, Organism=Drosophila melanogaster, GI24666501, Length=186, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-14, Organism=Drosophila melanogaster, GI24666497, Length=186, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.3 [H]
Molecular weight: Translated: 54767; Mature: 54635
Theoretical pI: Translated: 7.39; Mature: 7.39
Prosite motif: PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRHPQRTAFSWPGGSLSYQGAIDLIGRMQGVFMRLGLPPGTRVAFLTANRADAWCAGMA CCCCCCCCEECCCCCCEECCHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCHHHHHHH AQLSRLAITWLHPLGSLEDQLFQLSDSESQVLVIDAAAFRDRGGELAARADGLRHVFTLG HHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCHHHHCCCEEEEEEC PAGYGADLLAAIAQSGHATARNFARPDDLATLNYTGGTTGKSKGALRHHREYGGFATAIL CCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEE ADFEIPDRARYLTVAPISHVAGTKVLPTLMRGGTVHMLKGFDPEAVLDTIARERINFTLF ECCCCCCCCCEEEECCHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCEEEE VPTMIYVLLDHPALARTDLSSLELVLYGASAMSPTRLVEGIERIGPVFSQLYGQTECYPV HHHHHHHHHCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH SVLRKADHDPKQPELFLSCGFPIAACEVKILDDDDQEAPQGEAGEICVRAPHVMAEYWKR HHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHCC PDITAETLKNGWLRTGDIARRDERGYLYILDRKKDMIVSGGFNIFPREIEDVLTQHADVA CCCCHHHHHCCCEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCEE MCAVVGVPDDKWGEAVTAIVVPRAGAQPNATELIELVKARKGSAHAPKRVEFVKELPVTG EEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC VGKIDKKVLRAKYWEGRGRMVG CCHHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure SRHPQRTAFSWPGGSLSYQGAIDLIGRMQGVFMRLGLPPGTRVAFLTANRADAWCAGMA CCCCCCCEECCCCCCEECCHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCHHHHHHH AQLSRLAITWLHPLGSLEDQLFQLSDSESQVLVIDAAAFRDRGGELAARADGLRHVFTLG HHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHCCCCCCHHHHCCCEEEEEEC PAGYGADLLAAIAQSGHATARNFARPDDLATLNYTGGTTGKSKGALRHHREYGGFATAIL CCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEE ADFEIPDRARYLTVAPISHVAGTKVLPTLMRGGTVHMLKGFDPEAVLDTIARERINFTLF ECCCCCCCCCEEEECCHHHHCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCEEEE VPTMIYVLLDHPALARTDLSSLELVLYGASAMSPTRLVEGIERIGPVFSQLYGQTECYPV HHHHHHHHHCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH SVLRKADHDPKQPELFLSCGFPIAACEVKILDDDDQEAPQGEAGEICVRAPHVMAEYWKR HHHHHCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHCC PDITAETLKNGWLRTGDIARRDERGYLYILDRKKDMIVSGGFNIFPREIEDVLTQHADVA CCCCHHHHHCCCEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCEE MCAVVGVPDDKWGEAVTAIVVPRAGAQPNATELIELVKARKGSAHAPKRVEFVKELPVTG EEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC VGKIDKKVLRAKYWEGRGRMVG CCHHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]