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The map label for this gene is yegD [H]

Identifier: 146343294

GI number: 146343294

Start: 6765756

End: 6767015

Strand: Direct

Name: yegD [H]

Synonym: BRADO6516

Alternate gene names: 146343294

Gene position: 6765756-6767015 (Clockwise)

Preceding gene: 146343293

Following gene: 146343298

Centisome position: 90.74

GC content: 66.27

Gene sequence:

>1260_bases
ATGGCGGCAGCGGCCTATTGCGGCATCGACTTCGGCACTTCGAATACCACCGTTGGCCTCAGCGATCCCGCCTCTGCGCA
GCTCATCCCGCTGGAGGGCGAGCAGCGGACGTTGCCGAGCGCAATGTTCTTCGATTTCGAGCATCACGGCGTGCAGTTCG
GGCGCGCGGCGATCGAGCGCTATCTGACTGGGCATGACGGCCGCTTCATGCGCGCGCTGAAGAGCATTCTCGGCACCGCG
CTGATCCACGAGAAGACCTATATCCGGCAGAAGGCCGTTCCCTTCTCGGGCATTCTCGGCTTCTTCTTCGCGCATCTGAA
GTCGCAGATCGAGGCGCGCCTCGGCGACGACGTCGACCAGGTCGTGCTGGGCCGTCCCGTGCGCTTCGTCGACAAGGACG
ATGCCGCCGACGCCGAGGCGCAGAGCGCGCTCGAAGGCATCGCGCGCGAGCAGGGCTTCAAGCACATCGCATTCCAATAC
GAGCCGATCGCCGCCGCCCTCGACTACGAGCAGCAGGTGAACAGCGAGGAGCTCGTGCTGATCGTCGACATCGGCGGCGG
CACCTCCGACTTCTCGATCGTCCGCGTCTCGCCGGAGCGGCGCGGCAAGGCCGATCGCGAAGGCGACATCCTGGCCAATG
GCGGCATCCACATCGGCGGCACCGATTTCGACCGGCTGCTGAGCCTGAAGAGCGTCATGCCGCATCTCGGCTATGGCAGC
CTGACCGCCGACGGCAAGCGCGAGCTGCCGACGGCCTATTATCACGAGCTCGCCACCTGGCATCGCATCAACCAGCTCTA
CAAGAAGGGCGTCGTTCACGAGCTGCGCCAGATCCGCTACGAGGCCGAGCGGCGCGACCTCGTCGACCGCTTCATCAAGG
TGGTGGAGGAGCATCGCGGCCATACGCTGGCGATCGGCGTCGAGCAGGCGAAGATCGCGCTGACATCGGCGAAGTCGCTG
ACCTCGGTGCTGTCGGAAAAGGACGACTGGGCGCGCATCAAGTTCACGCGCAAGGATTTCGATCGCGCCATCGCCGATTC
CGTCGAGCGCGTCGTGCGCACCGTCACGACCTTGCTCGGCGATGCCAAGGTCGAGGCCGCCGCGATCAACACGATCTTCC
TCACCGGCGGCTCGAGCATGGTGCCGGCACTGCGCCAGGCGGTGCTCGCGCTGTTTCCGGACGCGCGCATCGCCGAGACC
GACCTGCTCGGCAGCGTCGGCCTCGGGCTCGCGCTCGACGCGCGGCGCAAGTTCGGCTGA

Upstream 100 bases:

>100_bases
CATGTGCGACATCCTCATACCCATCATGCCTCACATTCGCACATGACATTGCACTGCGAAACGGCTAAGCGGACCGCCCC
CGGACGGAAACGAGACGAGC

Downstream 100 bases:

>100_bases
TCCGCCGGCTCATCGCTCCGCCGCGGGTGCCGCCGCGGCTTCCTGCGCGCGCAGCCCCTCTCGCCGCGGCGCTTGCGACG
ATGACGAAACACCCGGCGGG

Product: putative chaperone protein (yegD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MAAAAYCGIDFGTSNTTVGLSDPASAQLIPLEGEQRTLPSAMFFDFEHHGVQFGRAAIERYLTGHDGRFMRALKSILGTA
LIHEKTYIRQKAVPFSGILGFFFAHLKSQIEARLGDDVDQVVLGRPVRFVDKDDAADAEAQSALEGIAREQGFKHIAFQY
EPIAAALDYEQQVNSEELVLIVDIGGGTSDFSIVRVSPERRGKADREGDILANGGIHIGGTDFDRLLSLKSVMPHLGYGS
LTADGKRELPTAYYHELATWHRINQLYKKGVVHELRQIRYEAERRDLVDRFIKVVEEHRGHTLAIGVEQAKIALTSAKSL
TSVLSEKDDWARIKFTRKDFDRAIADSVERVVRTVTTLLGDAKVEAAAINTIFLTGGSSMVPALRQAVLALFPDARIAET
DLLGSVGLGLALDARRKFG

Sequences:

>Translated_419_residues
MAAAAYCGIDFGTSNTTVGLSDPASAQLIPLEGEQRTLPSAMFFDFEHHGVQFGRAAIERYLTGHDGRFMRALKSILGTA
LIHEKTYIRQKAVPFSGILGFFFAHLKSQIEARLGDDVDQVVLGRPVRFVDKDDAADAEAQSALEGIAREQGFKHIAFQY
EPIAAALDYEQQVNSEELVLIVDIGGGTSDFSIVRVSPERRGKADREGDILANGGIHIGGTDFDRLLSLKSVMPHLGYGS
LTADGKRELPTAYYHELATWHRINQLYKKGVVHELRQIRYEAERRDLVDRFIKVVEEHRGHTLAIGVEQAKIALTSAKSL
TSVLSEKDDWARIKFTRKDFDRAIADSVERVVRTVTTLLGDAKVEAAAINTIFLTGGSSMVPALRQAVLALFPDARIAET
DLLGSVGLGLALDARRKFG
>Mature_418_residues
AAAAYCGIDFGTSNTTVGLSDPASAQLIPLEGEQRTLPSAMFFDFEHHGVQFGRAAIERYLTGHDGRFMRALKSILGTAL
IHEKTYIRQKAVPFSGILGFFFAHLKSQIEARLGDDVDQVVLGRPVRFVDKDDAADAEAQSALEGIAREQGFKHIAFQYE
PIAAALDYEQQVNSEELVLIVDIGGGTSDFSIVRVSPERRGKADREGDILANGGIHIGGTDFDRLLSLKSVMPHLGYGSL
TADGKRELPTAYYHELATWHRINQLYKKGVVHELRQIRYEAERRDLVDRFIKVVEEHRGHTLAIGVEQAKIALTSAKSLT
SVLSEKDDWARIKFTRKDFDRAIADSVERVVRTVTTLLGDAKVEAAAINTIFLTGGSSMVPALRQAVLALFPDARIAETD
LLGSVGLGLALDARRKFG

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI87082035, Length=450, Percent_Identity=28.2222222222222, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323401, Length=450, Percent_Identity=24.4444444444444, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322505, Length=413, Percent_Identity=24.455205811138, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320805, Length=437, Percent_Identity=23.3409610983982, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 46021; Mature: 45890

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00501 SPASE_I_1 ; PS00329 HSP70_2 ; PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAAYCGIDFGTSNTTVGLSDPASAQLIPLEGEQRTLPSAMFFDFEHHGVQFGRAAIER
CCCCEEECEEECCCCCEEECCCCCCCEEEECCCCCCCCCHHHEECCHHHCHHHHHHHHHH
YLTGHDGRFMRALKSILGTALIHEKTYIRQKAVPFSGILGFFFAHLKSQIEARLGDDVDQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VVLGRPVRFVDKDDAADAEAQSALEGIAREQGFKHIAFQYEPIAAALDYEQQVNSEELVL
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCHHHHCCCCCEEE
IVDIGGGTSDFSIVRVSPERRGKADREGDILANGGIHIGGTDFDRLLSLKSVMPHLGYGS
EEECCCCCCCEEEEEECHHHCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCC
LTADGKRELPTAYYHELATWHRINQLYKKGVVHELRQIRYEAERRDLVDRFIKVVEEHRG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HTLAIGVEQAKIALTSAKSLTSVLSEKDDWARIKFTRKDFDRAIADSVERVVRTVTTLLG
CEEEEECCHHHEEHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
DAKVEAAAINTIFLTGGSSMVPALRQAVLALFPDARIAETDLLGSVGLGLALDARRKFG
CCHHHEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCHHCCC
>Mature Secondary Structure 
AAAAYCGIDFGTSNTTVGLSDPASAQLIPLEGEQRTLPSAMFFDFEHHGVQFGRAAIER
CCCEEECEEECCCCCEEECCCCCCCEEEECCCCCCCCCHHHEECCHHHCHHHHHHHHHH
YLTGHDGRFMRALKSILGTALIHEKTYIRQKAVPFSGILGFFFAHLKSQIEARLGDDVDQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VVLGRPVRFVDKDDAADAEAQSALEGIAREQGFKHIAFQYEPIAAALDYEQQVNSEELVL
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCHHHHCCCCCEEE
IVDIGGGTSDFSIVRVSPERRGKADREGDILANGGIHIGGTDFDRLLSLKSVMPHLGYGS
EEECCCCCCCEEEEEECHHHCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCC
LTADGKRELPTAYYHELATWHRINQLYKKGVVHELRQIRYEAERRDLVDRFIKVVEEHRG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HTLAIGVEQAKIALTSAKSLTSVLSEKDDWARIKFTRKDFDRAIADSVERVVRTVTTLLG
CEEEEECCHHHEEHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
DAKVEAAAINTIFLTGGSSMVPALRQAVLALFPDARIAETDLLGSVGLGLALDARRKFG
CCHHHEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]