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The map label for this gene is pcm2 [H]

Identifier: 146343041

GI number: 146343041

Start: 6473172

End: 6474047

Strand: Reverse

Name: pcm2 [H]

Synonym: BRADO6231

Alternate gene names: 146343041

Gene position: 6474047-6473172 (Counterclockwise)

Preceding gene: 146343042

Following gene: 146343038

Centisome position: 86.82

GC content: 67.92

Gene sequence:

>876_bases
GTGGATCAATCAGAGAAATACCGCACGTTCTACGCCAAGCTGATCTGCGCCGCCGCCAAGCTCGAGGATCCCCGGATCGA
GGAGGCGTTCCGCAGCATCCCGCGCGAGCCATTCGCGGGGCCGGGGCCCTGGTGGATGATCCTCGGCGGCGGTCATCCTT
ATGTGCAGACGCCCGATGACGATCCTGCCTTCCTCTATCAGAACCTGCTGCTCGCGCTGGACTACGAACGCGGCATCAAT
ATCGGCCAGCCTGGCGCACATGCGATGTGGCTGGGCGCCTGCGGCATCAAGCCGGCCGACACCGTGGTGCATGTCGGGGT
CGGCAGCGGCTACTACACGGCGATCCTCGCGCATCTGGTCGGTCCGCACGGGCGGGTCCATGCCTATGAGATCGACGAGG
CGATGGCCGCGCGAGCGCGCGAGAACCTCGAGCATGTGCCGCAGGTGGAGCTGCGGCTGCAATCCGGCGCCGGGGCGGAC
CTGCCGCCGGCCGACGTGATCTATGTCTGTGCCGGCGCGGCGCAGCCGAGCCGGTCCTGGCTCGATGGCTTGCGGCCGGG
CGGACGGCTATTGTTTCCCTTGGCGCCGCAGGACGTCTTCGGCGGCATGTTGCTGATCACGCGTCCCGGTCAAGGCACGG
TCTGGCCGGCGAAATTCGTCAGTCGCGCCGGGTTTATCGGATGCGTCGGCCTGCAGGACGAGAACGCGGGCCGCCGCTTG
AGCGCGGCGTTCTCGACGGATTGGGCCGCCGTGCGCTCGTTGCGTCTCGACGGAGCGCCGGACGAGAGCTGCTGGTTCGC
CGGCGACGGCTGGTGGCTATCGACGGCGGAGGCTTTGGGGTCCTCTGATCCATCCGAGCACGATCCGCGACGCTGA

Upstream 100 bases:

>100_bases
TGACGACGAAGCAGATGTTTAAGAGGTATTATTGTACAACGATGCGGTGAGCGGTGTAAGGTCGGGGCTTGCTTGTCAGC
ATCACCCGCGAGGCCCCGTC

Downstream 100 bases:

>100_bases
CCTTGCGTCGACCGGATTCGCGCGGCGATCGTGATCGCGCGATCACGACGGCATCGTCCAGCCTTGCGGTCACCTCGTCA
GGTGCGCCTCGGAGACCGCA

Product: putative protein-L-isoaspartate(D-aspartate) O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase 2; Protein L-isoaspartyl methyltransferase 2; Protein-beta-aspartate methyltransferase 2; PIMT 2 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDQSEKYRTFYAKLICAAAKLEDPRIEEAFRSIPREPFAGPGPWWMILGGGHPYVQTPDDDPAFLYQNLLLALDYERGIN
IGQPGAHAMWLGACGIKPADTVVHVGVGSGYYTAILAHLVGPHGRVHAYEIDEAMAARARENLEHVPQVELRLQSGAGAD
LPPADVIYVCAGAAQPSRSWLDGLRPGGRLLFPLAPQDVFGGMLLITRPGQGTVWPAKFVSRAGFIGCVGLQDENAGRRL
SAAFSTDWAAVRSLRLDGAPDESCWFAGDGWWLSTAEALGSSDPSEHDPRR

Sequences:

>Translated_291_residues
MDQSEKYRTFYAKLICAAAKLEDPRIEEAFRSIPREPFAGPGPWWMILGGGHPYVQTPDDDPAFLYQNLLLALDYERGIN
IGQPGAHAMWLGACGIKPADTVVHVGVGSGYYTAILAHLVGPHGRVHAYEIDEAMAARARENLEHVPQVELRLQSGAGAD
LPPADVIYVCAGAAQPSRSWLDGLRPGGRLLFPLAPQDVFGGMLLITRPGQGTVWPAKFVSRAGFIGCVGLQDENAGRRL
SAAFSTDWAAVRSLRLDGAPDESCWFAGDGWWLSTAEALGSSDPSEHDPRR
>Mature_291_residues
MDQSEKYRTFYAKLICAAAKLEDPRIEEAFRSIPREPFAGPGPWWMILGGGHPYVQTPDDDPAFLYQNLLLALDYERGIN
IGQPGAHAMWLGACGIKPADTVVHVGVGSGYYTAILAHLVGPHGRVHAYEIDEAMAARARENLEHVPQVELRLQSGAGAD
LPPADVIYVCAGAAQPSRSWLDGLRPGGRLLFPLAPQDVFGGMLLITRPGQGTVWPAKFVSRAGFIGCVGLQDENAGRRL
SAAFSTDWAAVRSLRLDGAPDESCWFAGDGWWLSTAEALGSSDPSEHDPRR

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 31503; Mature: 31503

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSEKYRTFYAKLICAAAKLEDPRIEEAFRSIPREPFAGPGPWWMILGGGHPYVQTPDD
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
DPAFLYQNLLLALDYERGINIGQPGAHAMWLGACGIKPADTVVHVGVGSGYYTAILAHLV
CHHHHHHHHHHEEEHHHCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
GPHGRVHAYEIDEAMAARARENLEHVPQVELRLQSGAGADLPPADVIYVCAGAAQPSRSW
CCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCHHH
LDGLRPGGRLLFPLAPQDVFGGMLLITRPGQGTVWPAKFVSRAGFIGCVGLQDENAGRRL
HHHCCCCCEEEEEECCHHHHCCEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCEE
SAAFSTDWAAVRSLRLDGAPDESCWFAGDGWWLSTAEALGSSDPSEHDPRR
EHHHCCCHHHHHHEECCCCCCCCEEECCCCCEEHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDQSEKYRTFYAKLICAAAKLEDPRIEEAFRSIPREPFAGPGPWWMILGGGHPYVQTPDD
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
DPAFLYQNLLLALDYERGINIGQPGAHAMWLGACGIKPADTVVHVGVGSGYYTAILAHLV
CHHHHHHHHHHEEEHHHCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHH
GPHGRVHAYEIDEAMAARARENLEHVPQVELRLQSGAGADLPPADVIYVCAGAAQPSRSW
CCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCHHH
LDGLRPGGRLLFPLAPQDVFGGMLLITRPGQGTVWPAKFVSRAGFIGCVGLQDENAGRRL
HHHCCCCCEEEEEECCHHHHCCEEEEEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCEE
SAAFSTDWAAVRSLRLDGAPDESCWFAGDGWWLSTAEALGSSDPSEHDPRR
EHHHCCCHHHHHHEECCCCCCCCEEECCCCCEEHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA