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The map label for this gene is feoB [H]

Identifier: 146342429

GI number: 146342429

Start: 5770131

End: 5772008

Strand: Direct

Name: feoB [H]

Synonym: BRADO5588

Alternate gene names: 146342429

Gene position: 5770131-5772008 (Clockwise)

Preceding gene: 146342428

Following gene: 146342431

Centisome position: 77.38

GC content: 66.67

Gene sequence:

>1878_bases
ATGGATAGCCCTCTGCTGCATCTGGCCCTGGTGGGGACACCCAACAGCGGCAAGACATCCCTATTCAACGCCCTGACGGG
CAGTCGTCAGAAGGTCGCGAACTATCCTGGCGTCACCGTCGAGCGCAAAGAGGGCGCGTTCGTGACGCCGCAGGGGCGCC
AGGTCTCGCTGGTCGACCTCCCCGGCACCTATTCGCTGCGCGGCCGCAGCCCGGACGAGGAAATCACCCGCGATTTCGTC
CTGGGACGGGCCACCGGCGAGGTTCTGCCGGACCTCGTATTGTGTGTTGCCGATTCCACCAACCTCCGGTTGACGATCCG
CCTCTTGCTCGAGCTCAAGAGCACCGGACGACCGCTGGCGCTGGTTCTCAACATGTTCGACATCGCCAAGCGCCGCGGCG
TGACGGTCGATGTCGCCGCCCTGTCGCAGGCGCTCGGCGTGCCCGTGGTGACCTCGATCGCCGTCCGCAAGGGCGGGACC
GACGACCTGCTGCAGCTGACCGATCGGCTGCTGTCCGAGGCAACTGCGGCAAGCGGCGATCGCGCCAATACCTGGCGGCC
GCTGACCGTGCCGGAGCTGCGCGCCACCCAGCGCGAGGCCGACCGCATCATCGCATCGACCGTCAGCCTGCCGGAGCGGC
CCGACACCTGGACGGCACGGATCGATTCCGTCGCTTTGCATCCGGTCGGCGGCCTGGTCATCCTGCTGGCCATTCTGTTC
ATCATGTTCCAGGGCGTGTTCGCCTGGGCGCAGCCCTTGATGCAGCTGCTGTCGGCGGCCTTCGACGCGCTCGGACAGCT
GGTTCATGACCAGCTGCCTGAAGGCCTGCTGCAGAGCTTCCTGCAGAACGGCGTGATCTCCGGCGTCGGCAGCGTGATCG
TCTTCCTGCCGCAGATCATCATCATCTTCCTGTTTATCCTGTTGCTCGAAGATTTCGGCTACATGGCGCGCGCGGCGTTC
CTGATGGACCGCATCATGGGCGGCGCCGGCCTGCACGGCCGCGCCTTCATCCCGCTGCTGTCGAGCTTCGCCTGCGCCAT
TCCCGGCATCATGGCGACGCGCGTGATCGACAACCGCCGCGACCGCCTGACCACGATCCTGATCGCGCCGCTGATGACCT
GCTCGGCACGCATCCCGGTCTATACGCTGATCATCTCGGCCTTCATCCCGCCGACCAAGGTCTGGGGCCTGATCAATCTG
CAGGGCCTCGTGATGTTCGGGCTCTATGCGGCCGGGATCGTCAGCGCGCTGCTGGTGTCGTTCCTGGTCAAGTTCTTCCT
GATGCGCGACTACCAGCCGGCGCCGTTCATGCTCGAGCTGCCCGACTACAAGATGCCGCGGCTGCGCAGCATCGCGATCG
GCGTCTACACCCGCGCCAAGATGTTCCTGCAGCGCGCCGGCACCACGATCTTCGCGATGATGGTGCTGATCTGGTTCCTG
GCCTCGTTCCCGCAGCCGCCTGCCGCCGCCACCGAGCCGGCGATCAATTACAGCCTGGCCGCGATGATCGGCCAGGCCAT
TGCGCCGCTGCTCCATCCGGTCGGCTTCAACTGGCAGATCGCGGTGGCGCTGGTGCCGGGCATGGCGGCCCGCGAGGTCG
CTGTGGCGGCGCTCGGCACGGTCTACGCGATCGAGGGCGGCAAGGAGGCGGCTGAGCAGATCGGCCAGGTGCTGGCCACC
AAATGGAGCCTCGCGACCGCGCTGGCGCTGCTCGCCTGGTACATCTTCGCGCCGCAATGCGCTTCCACGCTCGCTGTCAT
CCGCCGCGAGACCGGCAGCTGGCGCTGGATGGCAGTGACCTTCTTCTACATGTTCGCGCTGGCCTATGCGGCGGCATTCG
CGACCTACCACATCGCGGTGGCGATGGGCGCGGGCTGA

Upstream 100 bases:

>100_bases
GGATCCGATCGCCGTCCGGGTCGACAACATCACCGTCGCGGTCCGCCGGCGCGAGGCCATGGCCGTCATCGTGGCGTAGG
CCGCGCGGGAAGCGTCGACC

Downstream 100 bases:

>100_bases
GCCCACGCCCATCGGCCTCATCGCGCGATATGCAGCGCGAAGCCGTGGGCGTCGGAATCGCCAAGCCCGGGACGCAGCTG
CATCGACGGGATCAGATAGT

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MDSPLLHLALVGTPNSGKTSLFNALTGSRQKVANYPGVTVERKEGAFVTPQGRQVSLVDLPGTYSLRGRSPDEEITRDFV
LGRATGEVLPDLVLCVADSTNLRLTIRLLLELKSTGRPLALVLNMFDIAKRRGVTVDVAALSQALGVPVVTSIAVRKGGT
DDLLQLTDRLLSEATAASGDRANTWRPLTVPELRATQREADRIIASTVSLPERPDTWTARIDSVALHPVGGLVILLAILF
IMFQGVFAWAQPLMQLLSAAFDALGQLVHDQLPEGLLQSFLQNGVISGVGSVIVFLPQIIIIFLFILLLEDFGYMARAAF
LMDRIMGGAGLHGRAFIPLLSSFACAIPGIMATRVIDNRRDRLTTILIAPLMTCSARIPVYTLIISAFIPPTKVWGLINL
QGLVMFGLYAAGIVSALLVSFLVKFFLMRDYQPAPFMLELPDYKMPRLRSIAIGVYTRAKMFLQRAGTTIFAMMVLIWFL
ASFPQPPAAATEPAINYSLAAMIGQAIAPLLHPVGFNWQIAVALVPGMAAREVAVAALGTVYAIEGGKEAAEQIGQVLAT
KWSLATALALLAWYIFAPQCASTLAVIRRETGSWRWMAVTFFYMFALAYAAAFATYHIAVAMGAG

Sequences:

>Translated_625_residues
MDSPLLHLALVGTPNSGKTSLFNALTGSRQKVANYPGVTVERKEGAFVTPQGRQVSLVDLPGTYSLRGRSPDEEITRDFV
LGRATGEVLPDLVLCVADSTNLRLTIRLLLELKSTGRPLALVLNMFDIAKRRGVTVDVAALSQALGVPVVTSIAVRKGGT
DDLLQLTDRLLSEATAASGDRANTWRPLTVPELRATQREADRIIASTVSLPERPDTWTARIDSVALHPVGGLVILLAILF
IMFQGVFAWAQPLMQLLSAAFDALGQLVHDQLPEGLLQSFLQNGVISGVGSVIVFLPQIIIIFLFILLLEDFGYMARAAF
LMDRIMGGAGLHGRAFIPLLSSFACAIPGIMATRVIDNRRDRLTTILIAPLMTCSARIPVYTLIISAFIPPTKVWGLINL
QGLVMFGLYAAGIVSALLVSFLVKFFLMRDYQPAPFMLELPDYKMPRLRSIAIGVYTRAKMFLQRAGTTIFAMMVLIWFL
ASFPQPPAAATEPAINYSLAAMIGQAIAPLLHPVGFNWQIAVALVPGMAAREVAVAALGTVYAIEGGKEAAEQIGQVLAT
KWSLATALALLAWYIFAPQCASTLAVIRRETGSWRWMAVTFFYMFALAYAAAFATYHIAVAMGAG
>Mature_625_residues
MDSPLLHLALVGTPNSGKTSLFNALTGSRQKVANYPGVTVERKEGAFVTPQGRQVSLVDLPGTYSLRGRSPDEEITRDFV
LGRATGEVLPDLVLCVADSTNLRLTIRLLLELKSTGRPLALVLNMFDIAKRRGVTVDVAALSQALGVPVVTSIAVRKGGT
DDLLQLTDRLLSEATAASGDRANTWRPLTVPELRATQREADRIIASTVSLPERPDTWTARIDSVALHPVGGLVILLAILF
IMFQGVFAWAQPLMQLLSAAFDALGQLVHDQLPEGLLQSFLQNGVISGVGSVIVFLPQIIIIFLFILLLEDFGYMARAAF
LMDRIMGGAGLHGRAFIPLLSSFACAIPGIMATRVIDNRRDRLTTILIAPLMTCSARIPVYTLIISAFIPPTKVWGLINL
QGLVMFGLYAAGIVSALLVSFLVKFFLMRDYQPAPFMLELPDYKMPRLRSIAIGVYTRAKMFLQRAGTTIFAMMVLIWFL
ASFPQPPAAATEPAINYSLAAMIGQAIAPLLHPVGFNWQIAVALVPGMAAREVAVAALGTVYAIEGGKEAAEQIGQVLAT
KWSLATALALLAWYIFAPQCASTLAVIRRETGSWRWMAVTFFYMFALAYAAAFATYHIAVAMGAG

Specific function: It seems that the Fe(2+) uptake in C.jejuni cannot be attributed to feoB [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=733, Percent_Identity=32.4693042291951, Blast_Score=299, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011642
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07664 FeoB_C; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 67636; Mature: 67636

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSPLLHLALVGTPNSGKTSLFNALTGSRQKVANYPGVTVERKEGAFVTPQGRQVSLVDL
CCCCEEEEEEEECCCCCCHHHHHHHCCCHHHHCCCCCCEEECCCCCEECCCCCEEEEEEC
PGTYSLRGRSPDEEITRDFVLGRATGEVLPDLVLCVADSTNLRLTIRLLLELKSTGRPLA
CCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCEEHHHHHHHHHCCCCHHH
LVLNMFDIAKRRGVTVDVAALSQALGVPVVTSIAVRKGGTDDLLQLTDRLLSEATAASGD
HHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
RANTWRPLTVPELRATQREADRIIASTVSLPERPDTWTARIDSVALHPVGGLVILLAILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEECCHHHHHHHHHHHH
IMFQGVFAWAQPLMQLLSAAFDALGQLVHDQLPEGLLQSFLQNGVISGVGSVIVFLPQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
IIFLFILLLEDFGYMARAAFLMDRIMGGAGLHGRAFIPLLSSFACAIPGIMATRVIDNRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCH
DRLTTILIAPLMTCSARIPVYTLIISAFIPPTKVWGLINLQGLVMFGLYAAGIVSALLVS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVKFFLMRDYQPAPFMLELPDYKMPRLRSIAIGVYTRAKMFLQRAGTTIFAMMVLIWFL
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
ASFPQPPAAATEPAINYSLAAMIGQAIAPLLHPVGFNWQIAVALVPGMAAREVAVAALGT
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHH
VYAIEGGKEAAEQIGQVLATKWSLATALALLAWYIFAPQCASTLAVIRRETGSWRWMAVT
HEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
FFYMFALAYAAAFATYHIAVAMGAG
HHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MDSPLLHLALVGTPNSGKTSLFNALTGSRQKVANYPGVTVERKEGAFVTPQGRQVSLVDL
CCCCEEEEEEEECCCCCCHHHHHHHCCCHHHHCCCCCCEEECCCCCEECCCCCEEEEEEC
PGTYSLRGRSPDEEITRDFVLGRATGEVLPDLVLCVADSTNLRLTIRLLLELKSTGRPLA
CCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCEEHHHHHHHHHCCCCHHH
LVLNMFDIAKRRGVTVDVAALSQALGVPVVTSIAVRKGGTDDLLQLTDRLLSEATAASGD
HHHHHHHHHHHCCCEEEHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
RANTWRPLTVPELRATQREADRIIASTVSLPERPDTWTARIDSVALHPVGGLVILLAILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEECCHHHHHHHHHHHH
IMFQGVFAWAQPLMQLLSAAFDALGQLVHDQLPEGLLQSFLQNGVISGVGSVIVFLPQII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
IIFLFILLLEDFGYMARAAFLMDRIMGGAGLHGRAFIPLLSSFACAIPGIMATRVIDNRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCH
DRLTTILIAPLMTCSARIPVYTLIISAFIPPTKVWGLINLQGLVMFGLYAAGIVSALLVS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVKFFLMRDYQPAPFMLELPDYKMPRLRSIAIGVYTRAKMFLQRAGTTIFAMMVLIWFL
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
ASFPQPPAAATEPAINYSLAAMIGQAIAPLLHPVGFNWQIAVALVPGMAAREVAVAALGT
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHH
VYAIEGGKEAAEQIGQVLATKWSLATALALLAWYIFAPQCASTLAVIRRETGSWRWMAVT
HEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHH
FFYMFALAYAAAFATYHIAVAMGAG
HHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]