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The map label for this gene is iorB [C]

Identifier: 146342334

GI number: 146342334

Start: 5670491

End: 5672824

Strand: Direct

Name: iorB [C]

Synonym: BRADO5489

Alternate gene names: 146342334

Gene position: 5670491-5672824 (Clockwise)

Preceding gene: 146342333

Following gene: 146342336

Centisome position: 76.05

GC content: 67.35

Gene sequence:

>2334_bases
ATGACCATCATCGCAAATCCGGACATCGCGAGTTCCAACTCGCGCCGCGGCTTCGAGCGGCATCTCAAGGTCGAGAACGT
CTCGCGCCGCGCCATCTTGCAGACGCTAGGTCTCGCGGGCGGCTTCGTGCTCGCTGCGCCCCTGCTCTCGCGGCCCGCAT
TCGCCGCCTATGAGACCGGCGCCGGCAAGATGCCGCACGGCACCGTGGTCGATCCGAAGGTCTTCGTGTCGATCGCGCCC
GACGGCATCGTCTCGATCCTGGCGCATCGCTCCGAGATGGGCACCGGCGTGCGCACCAGCCTGCCGCTGATCGTGGCCGA
GGAGATGGAAGCCGACTGGACGAAGGTGCGCGTGGTGCAGGCGCCCGGCGACGAGGTGAAGTTCGGCAACCAGGACACCG
ACGGCTCGCGCAGCACACGGCACTATCTGTTGCCGATGCGCCAGATCGGCGCGATGGCGCGCGCGATGCTCGAAGCCGCT
GCCGCCAAGAAACTTGGCGTGCCCGCAAGCGAGGTGAAGGCGGTCAACCACGAGGTCGTGCACAGCGCCAGCGGCAAGCG
CCTCAGCTTCGGCGAGCTCGCGGCCGATGCGGCCAGCCAGCCGGTGCCCGCGGTCGACACCATCAAGCTGAAGTCGCCTG
GTGATTTCCGCTATCTCGGCAAGGGCCAGGTCAGCATCGTCGATCTCCGTGACATCACCGTCGGCAAGGCGAGCTACGGC
GCCGACGTCCGCCTGCCCGGCATGAAATACGCCGTCATCGCCCGGCCGCCGGTGACCGGCGGCAAGGTCAAGTCGTTCGA
CTCCGCCGAGGCGCTGAAAGTGTCCGGCGTCGAGAAGGTGCTCGAGGTCAAGGGCTGGCCGTGGCCATCGAAGTTCCAGC
CGCTTGGTGGTGTCGCTGTCATTGCGCGCAACACGGGCGCTGCGATCAAGGGCCGCGACGCCCTGAAGGTCGAGTGGGAC
GACGGTCCCAATGCGGCCTACGACTCGGTCGCCTATCGCGCCGAGCTCGAAGCCGCTGCGCGACAGCCGGGCCTTGTCGT
GCGCCAGGAAGGTGATGCCGAAGCGGCGCTGAAATCGGCCGACAAGGTGATCACCGGCGAGTACTACCTGCCGCATTTCG
CCCATGCCAGCATGGAGCCGCCGGTCGCGGTCGCCGACGTCAAGGGCGACAAGGCCGAGATCTGGGCGCCGGTGCAGAGC
CCCGGCGGCACCCGCGAGGACGTCGCCAAGACGCTGCAGATCCCGATCGAGAACGTGACCGTCAACGTCACCCTGCTCGG
CGGCGGCTTCGGCCGCAAATCGAAATGCGACTTCGCGCTCGAAGCCGCCCTGCTCTCCAAGGAGCTGGGCGCGCCGGTGA
AGGTGCAGTGGACGCGTGACGACGACATCCAGCACGATTTCCTGCACACGGTCTCGGTCGAGCGCATCGAGGCGGGGCTG
GACAAGAGCGGCAAGGTCGTCGCCTGGCGTCACCGCAGCGTCGCGCCGACGATCCTGTCGACCTTCGCGGCCGGCGCCGA
CCATGCCGCGCCGTTCGAGCTCGGCATGGGCCTCGTCGACATGCCGTTCGAGATCGCCAACATCCAATGCGAGAACCCCG
CCGCCAAGGCAATGACCCGCATCGGCTGGTTCCGCTCGGTCTCGAACATTCCGCGCGCCTTCGCCGTGCAGTCGATGGTC
GGCGAGATCGCCGCCGCCACTGGCCGCGACCAGAAGGAGATGCTGCTCGAGCTGATCGGCAGTCCGCGCGTCGTCAAGCT
CGCCTCGGTGAAGGATCTCTGGAACTATGGCGAGCCCTATGAGAGCTATCCGATCGACACCGGACGGCTGCGACGCGTTG
TCGAGTTCGTCGCGGAGAAGGGCAATTGGGGCCGCAGCGTTCCCAAGGGCCACGGGCTCGGCATCGCCGCACATCGCAGC
TTCGTCAGCTACATCGCCACCATCGTGGAGGTGTCGGTCGACGACAAGGGCAAGCTGACCGTGCATCAGGTCGACAGCGC
GATCGACTGCGGTGTGTTCGTCAACCCGGAGCGCATCCAGTCGCAGCTCGAAGGTGCTGCGATCATGGGGCTGAGCCTCG
CCAAATATGGCGAGGTCAGCTTTAAGAACGGCCGGGTGCAGCAGCGCAACTTCGACGACCATCAGGTGGTCCGGATCGAC
GAGGCGCCGCTGGTCACCAACGTGCACATCGTCCCGGCGGATGCCGAGACGCCGCCGAGCGGCGTCGGGGAGCCGGGCGT
GCCGCCATTCGCGCCGGCGCTCGCCAACGCGATCTTTGCCGCCACCGGCAAACGGCTGCGGGCGCTGCCAATCGGCAACC
AGCTCGCGACCTGA

Upstream 100 bases:

>100_bases
ATGACCAGATCCGGGACGCGATGTCCGGCAATATCTGCCGCTGCGGCTGCTATCAGCGCATCGAGAATGCGGTCCATCTG
GCCTCGACGGGGGTGTGATC

Downstream 100 bases:

>100_bases
CGGCCGCGACACGACGACGTCATCGGCCGGAGCAATCCGGCCGATGAGCGCCTCGACAGAGCTTTGATCTATCAGCGCCC
GTAGCGCACCGAGGCATAGC

Product: isoquinoline 1-oxidoreductase subunit beta

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MTIIANPDIASSNSRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETGAGKMPHGTVVDPKVFVSIAP
DGIVSILAHRSEMGTGVRTSLPLIVAEEMEADWTKVRVVQAPGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAA
AAKKLGVPASEVKAVNHEVVHSASGKRLSFGELAADAASQPVPAVDTIKLKSPGDFRYLGKGQVSIVDLRDITVGKASYG
ADVRLPGMKYAVIARPPVTGGKVKSFDSAEALKVSGVEKVLEVKGWPWPSKFQPLGGVAVIARNTGAAIKGRDALKVEWD
DGPNAAYDSVAYRAELEAAARQPGLVVRQEGDAEAALKSADKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQS
PGGTREDVAKTLQIPIENVTVNVTLLGGGFGRKSKCDFALEAALLSKELGAPVKVQWTRDDDIQHDFLHTVSVERIEAGL
DKSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAAKAMTRIGWFRSVSNIPRAFAVQSMV
GEIAAATGRDQKEMLLELIGSPRVVKLASVKDLWNYGEPYESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRS
FVSYIATIVEVSVDDKGKLTVHQVDSAIDCGVFVNPERIQSQLEGAAIMGLSLAKYGEVSFKNGRVQQRNFDDHQVVRID
EAPLVTNVHIVPADAETPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT

Sequences:

>Translated_777_residues
MTIIANPDIASSNSRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETGAGKMPHGTVVDPKVFVSIAP
DGIVSILAHRSEMGTGVRTSLPLIVAEEMEADWTKVRVVQAPGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAA
AAKKLGVPASEVKAVNHEVVHSASGKRLSFGELAADAASQPVPAVDTIKLKSPGDFRYLGKGQVSIVDLRDITVGKASYG
ADVRLPGMKYAVIARPPVTGGKVKSFDSAEALKVSGVEKVLEVKGWPWPSKFQPLGGVAVIARNTGAAIKGRDALKVEWD
DGPNAAYDSVAYRAELEAAARQPGLVVRQEGDAEAALKSADKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQS
PGGTREDVAKTLQIPIENVTVNVTLLGGGFGRKSKCDFALEAALLSKELGAPVKVQWTRDDDIQHDFLHTVSVERIEAGL
DKSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAAKAMTRIGWFRSVSNIPRAFAVQSMV
GEIAAATGRDQKEMLLELIGSPRVVKLASVKDLWNYGEPYESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRS
FVSYIATIVEVSVDDKGKLTVHQVDSAIDCGVFVNPERIQSQLEGAAIMGLSLAKYGEVSFKNGRVQQRNFDDHQVVRID
EAPLVTNVHIVPADAETPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT
>Mature_776_residues
TIIANPDIASSNSRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETGAGKMPHGTVVDPKVFVSIAPD
GIVSILAHRSEMGTGVRTSLPLIVAEEMEADWTKVRVVQAPGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAAA
AKKLGVPASEVKAVNHEVVHSASGKRLSFGELAADAASQPVPAVDTIKLKSPGDFRYLGKGQVSIVDLRDITVGKASYGA
DVRLPGMKYAVIARPPVTGGKVKSFDSAEALKVSGVEKVLEVKGWPWPSKFQPLGGVAVIARNTGAAIKGRDALKVEWDD
GPNAAYDSVAYRAELEAAARQPGLVVRQEGDAEAALKSADKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQSP
GGTREDVAKTLQIPIENVTVNVTLLGGGFGRKSKCDFALEAALLSKELGAPVKVQWTRDDDIQHDFLHTVSVERIEAGLD
KSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAAKAMTRIGWFRSVSNIPRAFAVQSMVG
EIAAATGRDQKEMLLELIGSPRVVKLASVKDLWNYGEPYESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRSF
VSYIATIVEVSVDDKGKLTVHQVDSAIDCGVFVNPERIQSQLEGAAIMGLSLAKYGEVSFKNGRVQQRNFDDHQVVRIDE
APLVTNVHIVPADAETPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=9e-12,
Organism=Escherichia coli, GI1789230, Length=486, Percent_Identity=24.4855967078189, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 82983; Mature: 82852

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIANPDIASSNSRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETG
CEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECC
AGKMPHGTVVDPKVFVSIAPDGIVSILAHRSEMGTGVRTSLPLIVAEEMEADWTKVRVVQ
CCCCCCCCEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEE
APGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAAAAKKLGVPASEVKAVNHEVV
CCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HSASGKRLSFGELAADAASQPVPAVDTIKLKSPGDFRYLGKGQVSIVDLRDITVGKASYG
HCCCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEEEEEECCCCCC
ADVRLPGMKYAVIARPPVTGGKVKSFDSAEALKVSGVEKVLEVKGWPWPSKFQPLGGVAV
CCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IARNTGAAIKGRDALKVEWDDGPNAAYDSVAYRAELEAAARQPGLVVRQEGDAEAALKSA
EEECCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHC
DKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQSPGGTREDVAKTLQIPIENVT
CCEEECCCCCCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEE
VNVTLLGGGFGRKSKCDFALEAALLSKELGAPVKVQWTRDDDIQHDFLHTVSVERIEAGL
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCC
DKSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAAKAMTR
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHCCCEECCCEEEEEEEECCHHHHHHHH
IGWFRSVSNIPRAFAVQSMVGEIAAATGRDQKEMLLELIGSPRVVKLASVKDLWNYGEPY
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHCCCCH
ESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRSFVSYIATIVEVSVDDKGKLT
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEE
VHQVDSAIDCGVFVNPERIQSQLEGAAIMGLSLAKYGEVSFKNGRVQQRNFDDHQVVRID
EEECCCCCCCCEEECHHHHHHHHCCEEEEEEEHHHCCCEEECCCCCCCCCCCCCEEEEEE
EAPLVTNVHIVPADAETPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT
CCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHCCC
>Mature Secondary Structure 
TIIANPDIASSNSRRGFERHLKVENVSRRAILQTLGLAGGFVLAAPLLSRPAFAAYETG
EEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEECC
AGKMPHGTVVDPKVFVSIAPDGIVSILAHRSEMGTGVRTSLPLIVAEEMEADWTKVRVVQ
CCCCCCCCEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEE
APGDEVKFGNQDTDGSRSTRHYLLPMRQIGAMARAMLEAAAAKKLGVPASEVKAVNHEVV
CCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
HSASGKRLSFGELAADAASQPVPAVDTIKLKSPGDFRYLGKGQVSIVDLRDITVGKASYG
HCCCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEEEEEECCCCCC
ADVRLPGMKYAVIARPPVTGGKVKSFDSAEALKVSGVEKVLEVKGWPWPSKFQPLGGVAV
CCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IARNTGAAIKGRDALKVEWDDGPNAAYDSVAYRAELEAAARQPGLVVRQEGDAEAALKSA
EEECCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHC
DKVITGEYYLPHFAHASMEPPVAVADVKGDKAEIWAPVQSPGGTREDVAKTLQIPIENVT
CCEEECCCCCCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEE
VNVTLLGGGFGRKSKCDFALEAALLSKELGAPVKVQWTRDDDIQHDFLHTVSVERIEAGL
EEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCC
DKSGKVVAWRHRSVAPTILSTFAAGADHAAPFELGMGLVDMPFEIANIQCENPAAKAMTR
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHCCCEECCCEEEEEEEECCHHHHHHHH
IGWFRSVSNIPRAFAVQSMVGEIAAATGRDQKEMLLELIGSPRVVKLASVKDLWNYGEPY
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHCCCCH
ESYPIDTGRLRRVVEFVAEKGNWGRSVPKGHGLGIAAHRSFVSYIATIVEVSVDDKGKLT
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCEE
VHQVDSAIDCGVFVNPERIQSQLEGAAIMGLSLAKYGEVSFKNGRVQQRNFDDHQVVRID
EEECCCCCCCCEEECHHHHHHHHCCEEEEEEEHHHCCCEEECCCCCCCCCCCCCEEEEEE
EAPLVTNVHIVPADAETPPSGVGEPGVPPFAPALANAIFAATGKRLRALPIGNQLAT
CCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]