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The map label for this gene is feaR [H]

Identifier: 146342328

GI number: 146342328

Start: 5664118

End: 5665140

Strand: Reverse

Name: feaR [H]

Synonym: BRADO5483

Alternate gene names: 146342328

Gene position: 5665140-5664118 (Counterclockwise)

Preceding gene: 146342335

Following gene: 146342324

Centisome position: 75.97

GC content: 62.46

Gene sequence:

>1023_bases
CTGTCAGCACTCTCATCCGCCGTCCTGCGGCGGACCCGTTGCGTCTCGATCTTGAATCGGTGGATGAAGATGTCCGATAC
GATCCGCTCGCTTACCACCTCCGGGTTCTCACCCAAGAGTCAGATCCAGCGTTGGTCAGATGCACTGACCGATCTCTGTG
GGCGCTTCGATGTCGATCCGTTGGAAGGCGCCTCGTTCGAGGGACGCATCAACTTCACCACCGTCTCGCGCTTGAAGCTG
TGCCAGATCGAGGCGAGCCAGCACCGCATCGCACACACCTATGCGCGGGCGCAAAAGGTGGCGCATCCCTACATCAAGAT
CCTGTTCCAGACCTACGGGACCTCCTATTTTGAGCAGGATGGCCGCCAGATCGAGATCGGTCCCGGCGATTGCCTTGCTT
ATGATGTGTCGACGCCGCACACCATCATCAGCCCGGCGCTGACACGCCATGACGTCGTGATCGTGCCGAAGGAACTGCTG
CAGGAGCGCGGCTTCCGGTCCGAGAAGATGCCGGCCTACAAGCTCTCGGCCCGCAGCGGCACCGGCCGGATCGCGCACGA
TGTCACGCATTCCGCGTTCGACGAGGCGACACGGTTGTCACCGAACTCGGCGGCCAGCGTCGCCGAGTCGCTGATTGATC
TGTTGCTGCTGCCGTTGCGCGAAGCGGATCGCATGCTCGACCGGGCCGGGCCCGAAGCCGTCTACATCCGCGCGCAGGCC
TTCATTCGCGAGCACCTGCGCGATCCCGATCTCTGCATCGACCAGATCTCGGCAGCCTTGGGTTGTACCAAGCGCTACCT
CCATATGGTCTTCAGCGACCGGGGCATGACGGTGAGCGACTACATCTGGCGCGCAAGGTTGCAGCACTGTCGCCAGGAGC
TGGAAACGCAAGGCGGTAAGACCATCACCGACGTCGCGTTCTCCTGGGGCTTCTCGAGCTCCTCCCACTTCAGCCGCGTG
TTCCGCAAATATTTCGGCGTGGTGCCGTCGTCGGTGCACAAGACGGCTGCGCGCGCCGACTAA

Upstream 100 bases:

>100_bases
TTTTCTTGACCTTGCAGAGACGAAGGCGGAGGATCGTCGAGGGCGTTTTATGGAACTGATGTGTCGCGAAGGGATATCGC
GGCCTTAAAATCGGAGTAAT

Downstream 100 bases:

>100_bases
GCGGGACGGCCCTAGCGCGCGCCACCCCGGATGATCTTTTGAAACGCATCGCCGAGAATCATCGGCTCGCGTGGGGGCAG
GTAGGTCAGACCGGCCGACC

Product: AraC/XylS family transcription factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSALSSAVLRRTRCVSILNRWMKMSDTIRSLTTSGFSPKSQIQRWSDALTDLCGRFDVDPLEGASFEGRINFTTVSRLKL
CQIEASQHRIAHTYARAQKVAHPYIKILFQTYGTSYFEQDGRQIEIGPGDCLAYDVSTPHTIISPALTRHDVVIVPKELL
QERGFRSEKMPAYKLSARSGTGRIAHDVTHSAFDEATRLSPNSAASVAESLIDLLLLPLREADRMLDRAGPEAVYIRAQA
FIREHLRDPDLCIDQISAALGCTKRYLHMVFSDRGMTVSDYIWRARLQHCRQELETQGGKTITDVAFSWGFSSSSHFSRV
FRKYFGVVPSSVHKTAARAD

Sequences:

>Translated_340_residues
MSALSSAVLRRTRCVSILNRWMKMSDTIRSLTTSGFSPKSQIQRWSDALTDLCGRFDVDPLEGASFEGRINFTTVSRLKL
CQIEASQHRIAHTYARAQKVAHPYIKILFQTYGTSYFEQDGRQIEIGPGDCLAYDVSTPHTIISPALTRHDVVIVPKELL
QERGFRSEKMPAYKLSARSGTGRIAHDVTHSAFDEATRLSPNSAASVAESLIDLLLLPLREADRMLDRAGPEAVYIRAQA
FIREHLRDPDLCIDQISAALGCTKRYLHMVFSDRGMTVSDYIWRARLQHCRQELETQGGKTITDVAFSWGFSSSSHFSRV
FRKYFGVVPSSVHKTAARAD
>Mature_339_residues
SALSSAVLRRTRCVSILNRWMKMSDTIRSLTTSGFSPKSQIQRWSDALTDLCGRFDVDPLEGASFEGRINFTTVSRLKLC
QIEASQHRIAHTYARAQKVAHPYIKILFQTYGTSYFEQDGRQIEIGPGDCLAYDVSTPHTIISPALTRHDVVIVPKELLQ
ERGFRSEKMPAYKLSARSGTGRIAHDVTHSAFDEATRLSPNSAASVAESLIDLLLLPLREADRMLDRAGPEAVYIRAQAF
IREHLRDPDLCIDQISAALGCTKRYLHMVFSDRGMTVSDYIWRARLQHCRQELETQGGKTITDVAFSWGFSSSSHFSRVF
RKYFGVVPSSVHKTAARAD

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=296, Percent_Identity=23.9864864864865, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38221; Mature: 38090

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALSSAVLRRTRCVSILNRWMKMSDTIRSLTTSGFSPKSQIQRWSDALTDLCGRFDVDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
LEGASFEGRINFTTVSRLKLCQIEASQHRIAHTYARAQKVAHPYIKILFQTYGTSYFEQD
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
GRQIEIGPGDCLAYDVSTPHTIISPALTRHDVVIVPKELLQERGFRSEKMPAYKLSARSG
CCEEEECCCCEEEEECCCCHHHHHHHHHHCCEEEECHHHHHHCCCCCCCCCCEEEECCCC
TGRIAHDVTHSAFDEATRLSPNSAASVAESLIDLLLLPLREADRMLDRAGPEAVYIRAQA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
FIREHLRDPDLCIDQISAALGCTKRYLHMVFSDRGMTVSDYIWRARLQHCRQELETQGGK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TITDVAFSWGFSSSSHFSRVFRKYFGVVPSSVHKTAARAD
CHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SALSSAVLRRTRCVSILNRWMKMSDTIRSLTTSGFSPKSQIQRWSDALTDLCGRFDVDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
LEGASFEGRINFTTVSRLKLCQIEASQHRIAHTYARAQKVAHPYIKILFQTYGTSYFEQD
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
GRQIEIGPGDCLAYDVSTPHTIISPALTRHDVVIVPKELLQERGFRSEKMPAYKLSARSG
CCEEEECCCCEEEEECCCCHHHHHHHHHHCCEEEECHHHHHHCCCCCCCCCCEEEECCCC
TGRIAHDVTHSAFDEATRLSPNSAASVAESLIDLLLLPLREADRMLDRAGPEAVYIRAQA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
FIREHLRDPDLCIDQISAALGCTKRYLHMVFSDRGMTVSDYIWRARLQHCRQELETQGGK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
TITDVAFSWGFSSSSHFSRVFRKYFGVVPSSVHKTAARAD
CHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]