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The map label for this gene is modD [H]

Identifier: 146342228

GI number: 146342228

Start: 5587586

End: 5588446

Strand: Reverse

Name: modD [H]

Synonym: BRADO5380

Alternate gene names: 146342228

Gene position: 5588446-5587586 (Counterclockwise)

Preceding gene: 146342230

Following gene: 146342223

Centisome position: 74.95

GC content: 69.45

Gene sequence:

>861_bases
GTGCCGACCACCGTGACGCACCATGATCTGGAAGCGCTGCTCCGGGACGATGTGCCCTATGGCGACCTGACCACGGAGGT
GCTCGGAATCGGCGCCGAGCCTGCGGAGATGTTGTTCGTCGCGCGCGACCGGATGGTGCTGGCGCTCGCAGAGGACGCCG
CCGCGCTGATCGAGCTGGCCGGTGGCCGTGTCGAACAGCTTGCAGCCAGCGGTGCGGCACTCGAGAAGGGCGCGCCGATC
CTGCGGGCGCGAGGGGGCGCCGCCGGCCTGCTGCGCAGCTGGAAGGTCGCGCAAACGCTGATCGAGATCTGGTCGGGTGT
CGCCACGGAGGCCGCCGCCATCGTGGGTGCCGCGCGCGCGGCAAGGCCCGGCATTGCCGTGGCCTGCACGCGCAAGAATG
TCCCGGGCACCAAGCAGTACGCCGTGGCTGCGGTGAAGGCGGGTGGAGCCGTGATGCATCGGCTCGGCCTGTCCGAGACC
ATCCTCGTTTTCCCGGAGCATCGGGCGTTTCTTGGCGAGACGCCGCTCGCCGACATTGCCGAGCGGTTGCGCCGTACCGC
TCCGGAAAAGCGTCTCGTCATCGAGGTCACGACCATCGAGCACGCCGTGGCGGCTGCTGCCGCCGGCTTCGACGTCATCC
AAGCTGAAAAATTTCCGCCTGCCGACATCGCGGCACTGGTTCAACGCGTGAGGACGCTGGCCACCTTGCCGGTCCGGCCG
ATCGTTGCGGCCGCGGGCGGCGTCAATGCGCGGAACGCCGCGGCCTATGCCGAGGCTGGCGCCGATGTGCTCGTCACCTC
CGCGCCTTATCTCGCGCGTCCCTGCGACGTGCAGGTCAGGATCACCAGGGCAGCGGCCTGA

Upstream 100 bases:

>100_bases
TTCGGCCCGTCCACCTCATGTCAGGCCTGCCATCGTGAGCGTGCAGGGCGCCGTATATATATCGGGAATAAGGCCTGCCT
ACCAACAGGAGATCTCGCAC

Downstream 100 bases:

>100_bases
CGCTTTGCATCGATCATTGCGGCGGCCGGGCGGCCGGCCGCTTCTGGCGGTTGGCCCGCCACTCCAGGAACTCGCGAAAC
AGTTTCGGGTCGTTCGCCGC

Product: putative pyrophosphorylase modD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPTTVTHHDLEALLRDDVPYGDLTTEVLGIGAEPAEMLFVARDRMVLALAEDAAALIELAGGRVEQLAASGAALEKGAPI
LRARGGAAGLLRSWKVAQTLIEIWSGVATEAAAIVGAARAARPGIAVACTRKNVPGTKQYAVAAVKAGGAVMHRLGLSET
ILVFPEHRAFLGETPLADIAERLRRTAPEKRLVIEVTTIEHAVAAAAAGFDVIQAEKFPPADIAALVQRVRTLATLPVRP
IVAAAGGVNARNAAAYAEAGADVLVTSAPYLARPCDVQVRITRAAA

Sequences:

>Translated_286_residues
MPTTVTHHDLEALLRDDVPYGDLTTEVLGIGAEPAEMLFVARDRMVLALAEDAAALIELAGGRVEQLAASGAALEKGAPI
LRARGGAAGLLRSWKVAQTLIEIWSGVATEAAAIVGAARAARPGIAVACTRKNVPGTKQYAVAAVKAGGAVMHRLGLSET
ILVFPEHRAFLGETPLADIAERLRRTAPEKRLVIEVTTIEHAVAAAAAGFDVIQAEKFPPADIAALVQRVRTLATLPVRP
IVAAAGGVNARNAAAYAEAGADVLVTSAPYLARPCDVQVRITRAAA
>Mature_285_residues
PTTVTHHDLEALLRDDVPYGDLTTEVLGIGAEPAEMLFVARDRMVLALAEDAAALIELAGGRVEQLAASGAALEKGAPIL
RARGGAAGLLRSWKVAQTLIEIWSGVATEAAAIVGAARAARPGIAVACTRKNVPGTKQYAVAAVKAGGAVMHRLGLSETI
LVFPEHRAFLGETPLADIAERLRRTAPEKRLVIEVTTIEHAVAAAAAGFDVIQAEKFPPADIAALVQRVRTLATLPVRPI
VAAAGGVNARNAAAYAEAGADVLVTSAPYLARPCDVQVRITRAAA

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321162, Length=276, Percent_Identity=24.6376811594203, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 29674; Mature: 29542

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTVTHHDLEALLRDDVPYGDLTTEVLGIGAEPAEMLFVARDRMVLALAEDAAALIELA
CCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHEEECCCEEEEEHHHHHHHHHHC
GGRVEQLAASGAALEKGAPILRARGGAAGLLRSWKVAQTLIEIWSGVATEAAAIVGAARA
CCHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ARPGIAVACTRKNVPGTKQYAVAAVKAGGAVMHRLGLSETILVFPEHRAFLGETPLADIA
CCCCEEEEEECCCCCCCHHHEEEEHHCCHHHHHHCCCCCEEEEEECCHHHCCCCCHHHHH
ERLRRTAPEKRLVIEVTTIEHAVAAAAAGFDVIQAEKFPPADIAALVQRVRTLATLPVRP
HHHHHCCCCCEEEEEEEHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHH
IVAAAGGVNARNAAAYAEAGADVLVTSAPYLARPCDVQVRITRAAA
HHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
PTTVTHHDLEALLRDDVPYGDLTTEVLGIGAEPAEMLFVARDRMVLALAEDAAALIELA
CCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHEEECCCEEEEEHHHHHHHHHHC
GGRVEQLAASGAALEKGAPILRARGGAAGLLRSWKVAQTLIEIWSGVATEAAAIVGAARA
CCHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ARPGIAVACTRKNVPGTKQYAVAAVKAGGAVMHRLGLSETILVFPEHRAFLGETPLADIA
CCCCEEEEEECCCCCCCHHHEEEEHHCCHHHHHHCCCCCEEEEEECCHHHCCCCCHHHHH
ERLRRTAPEKRLVIEVTTIEHAVAAAAAGFDVIQAEKFPPADIAALVQRVRTLATLPVRP
HHHHHCCCCCEEEEEEEHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCHH
IVAAAGGVNARNAAAYAEAGADVLVTSAPYLARPCDVQVRITRAAA
HHHHCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8491722 [H]