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The map label for this gene is cusB [H]

Identifier: 146341627

GI number: 146341627

Start: 4916583

End: 4917710

Strand: Direct

Name: cusB [H]

Synonym: BRADO4730

Alternate gene names: 146341627

Gene position: 4916583-4917710 (Clockwise)

Preceding gene: 146341624

Following gene: 146341628

Centisome position: 65.94

GC content: 68.26

Gene sequence:

>1128_bases
ATGCGCCCCGAAGCGGCTGTCGCGACCAAACCCGCAGAGGTCCAAGCGCCGCCCGCCGTCAACGCCGCCGAGCAGACCGT
CGAGCTGACCCCTCACCAGGTCGAGGCGCTCAAGGTCGAGACCGTCGGGCTGCACGCCTTTCGGGTGGTCAGAAACACCG
TCGGCTCGATCGACTTCAATCAGAACATGCTGGTGCAGGCGTTTACGCCGAATGCAGGCAAGATCGTCGATACGTTCTTC
AACGTCGGCGACGAGGTCAAACGCGGCGAGGCGCTGTTCACGATCGACAGTCCCGACCTGTTGCAGGCGGAATCGAGCCT
GCTCGCGGCGGCCGGCGTGCTCGAATTGCAGACGCGCACCCTCGCGCGCGTGCAGCAGTTGCTCAAGGCCGGCGGCGGCG
CGCAGAAGGACGTCGACCAGGCGACATCGGATCAGCAGACCGCCGACGGCAACTACAAGGCCGCGCGCGACGCCGTGCGC
ATCTTCGGCAAGACCGACGCCGAGATCGACCGGATTCTGGCGCAGCGCAAGGTCGATTCGATCCTGATCGTGCGCTCGCC
GATCTCGGGCCGCATCATCGCGCGCAACGCCGCACCCGGCATCTATGCCCAGCCCGGCACGTCGCCCGCGCCCTACACGC
TCGCCGATCTCTCCACAATGTGGATGGTCGCCAATGTGATCGAGACCGACGCGCCGGCCTACCGGCTCGATCAGCCGGTC
GAGGTCACCGTGCCGGCCTATCCCGGCGAGATCTTCCGGGGACGGGTGACGACGCTCGGGCTGAACATCGATCCGACGAC
GCACCGCCAGCTGGTTCGCTCGGTCATCGACGATCCCGCGCACAAGCTGCGCGCGGGCATGCTGGCGAGCTTCAGCATCG
AGACCGAGGCGCCACGCGCCTCGCCCGCGGTCCCCGCCGAGGCGCTGGTGCGCGAAGGCGACGGCAGCATGACCGTCTGG
GTCACGACCGACGGCAAGCGCTTCGTCCGCCGCGCCGTCACCGTGGGCCTGACTCAGGACGGCTGGCGGCAGATCCTGAC
AGGACTCGCCGCCGGCGAGCAGGTCGCAACCACAGGCGCGATCTTCCTCAGCAACGCCTTCGCCAACGCCGCGTCCGGCG
CGTCTTAG

Upstream 100 bases:

>100_bases
GTGCACGTGAATACCGGACATCGCCGTGGCTCCATCTCCGATCAAATTCATGGCTCTCATCGCGGCGCCCGCCGCTCTCC
TTGCTGGCGCATGGCTTGCG

Downstream 100 bases:

>100_bases
AATCTCTCATCAGCCGGGCGACCCGGCTCCGCCACGCGTTCGGTCGATCATCTTGGTCAAGAGCCTCATCCAGTTCGGTC
TCACGCGCAGCGCCATCGTC

Product: HlyD family heavy metal efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRPEAAVATKPAEVQAPPAVNAAEQTVELTPHQVEALKVETVGLHAFRVVRNTVGSIDFNQNMLVQAFTPNAGKIVDTFF
NVGDEVKRGEALFTIDSPDLLQAESSLLAAAGVLELQTRTLARVQQLLKAGGGAQKDVDQATSDQQTADGNYKAARDAVR
IFGKTDAEIDRILAQRKVDSILIVRSPISGRIIARNAAPGIYAQPGTSPAPYTLADLSTMWMVANVIETDAPAYRLDQPV
EVTVPAYPGEIFRGRVTTLGLNIDPTTHRQLVRSVIDDPAHKLRAGMLASFSIETEAPRASPAVPAEALVREGDGSMTVW
VTTDGKRFVRRAVTVGLTQDGWRQILTGLAAGEQVATTGAIFLSNAFANAASGAS

Sequences:

>Translated_375_residues
MRPEAAVATKPAEVQAPPAVNAAEQTVELTPHQVEALKVETVGLHAFRVVRNTVGSIDFNQNMLVQAFTPNAGKIVDTFF
NVGDEVKRGEALFTIDSPDLLQAESSLLAAAGVLELQTRTLARVQQLLKAGGGAQKDVDQATSDQQTADGNYKAARDAVR
IFGKTDAEIDRILAQRKVDSILIVRSPISGRIIARNAAPGIYAQPGTSPAPYTLADLSTMWMVANVIETDAPAYRLDQPV
EVTVPAYPGEIFRGRVTTLGLNIDPTTHRQLVRSVIDDPAHKLRAGMLASFSIETEAPRASPAVPAEALVREGDGSMTVW
VTTDGKRFVRRAVTVGLTQDGWRQILTGLAAGEQVATTGAIFLSNAFANAASGAS
>Mature_375_residues
MRPEAAVATKPAEVQAPPAVNAAEQTVELTPHQVEALKVETVGLHAFRVVRNTVGSIDFNQNMLVQAFTPNAGKIVDTFF
NVGDEVKRGEALFTIDSPDLLQAESSLLAAAGVLELQTRTLARVQQLLKAGGGAQKDVDQATSDQQTADGNYKAARDAVR
IFGKTDAEIDRILAQRKVDSILIVRSPISGRIIARNAAPGIYAQPGTSPAPYTLADLSTMWMVANVIETDAPAYRLDQPV
EVTVPAYPGEIFRGRVTTLGLNIDPTTHRQLVRSVIDDPAHKLRAGMLASFSIETEAPRASPAVPAEALVREGDGSMTVW
VTTDGKRFVRRAVTVGLTQDGWRQILTGLAAGEQVATTGAIFLSNAFANAASGAS

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=354, Percent_Identity=26.5536723163842, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790519, Length=237, Percent_Identity=26.5822784810127, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39918; Mature: 39918

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPEAAVATKPAEVQAPPAVNAAEQTVELTPHQVEALKVETVGLHAFRVVRNTVGSIDFN
CCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCC
QNMLVQAFTPNAGKIVDTFFNVGDEVKRGEALFTIDSPDLLQAESSLLAAAGVLELQTRT
CCEEEEEECCCCCHHHHHHHCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LARVQQLLKAGGGAQKDVDQATSDQQTADGNYKAARDAVRIFGKTDAEIDRILAQRKVDS
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCE
ILIVRSPISGRIIARNAAPGIYAQPGTSPAPYTLADLSTMWMVANVIETDAPAYRLDQPV
EEEEECCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCE
EVTVPAYPGEIFRGRVTTLGLNIDPTTHRQLVRSVIDDPAHKLRAGMLASFSIETEAPRA
EEEECCCCCHHHCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCCCC
SPAVPAEALVREGDGSMTVWVTTDGKRFVRRAVTVGLTQDGWRQILTGLAAGEQVATTGA
CCCCCHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
IFLSNAFANAASGAS
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPEAAVATKPAEVQAPPAVNAAEQTVELTPHQVEALKVETVGLHAFRVVRNTVGSIDFN
CCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCC
QNMLVQAFTPNAGKIVDTFFNVGDEVKRGEALFTIDSPDLLQAESSLLAAAGVLELQTRT
CCEEEEEECCCCCHHHHHHHCCCCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LARVQQLLKAGGGAQKDVDQATSDQQTADGNYKAARDAVRIFGKTDAEIDRILAQRKVDS
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCE
ILIVRSPISGRIIARNAAPGIYAQPGTSPAPYTLADLSTMWMVANVIETDAPAYRLDQPV
EEEEECCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCE
EVTVPAYPGEIFRGRVTTLGLNIDPTTHRQLVRSVIDDPAHKLRAGMLASFSIETEAPRA
EEEECCCCCHHHCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCCCC
SPAVPAEALVREGDGSMTVWVTTDGKRFVRRAVTVGLTQDGWRQILTGLAAGEQVATTGA
CCCCCHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
IFLSNAFANAASGAS
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]