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The map label for this gene is rpiA [H]

Identifier: 146341613

GI number: 146341613

Start: 4902619

End: 4903311

Strand: Reverse

Name: rpiA [H]

Synonym: BRADO4714

Alternate gene names: 146341613

Gene position: 4903311-4902619 (Counterclockwise)

Preceding gene: 146341619

Following gene: 146341612

Centisome position: 65.76

GC content: 67.1

Gene sequence:

>693_bases
ATGGATGCATTGAAGCGGCAGGCGGCGGCGCGTGCGCTGGAAGAAGTCGAGAGCGGCATGAAGCTCGGCCTCGGCACCGG
CTCGACCGCCAAGCATTTCGTCGATCTGCTGGGCGAGAAGGTGCGCGCCGGCCTCAAGGTGGTGGGCGTTCCGACCTCCG
AGGCGACGCGGGCGCAGGCCGAAGCTTGCGGCGTGCCGCTCACCACGCTCGACGAGATCGACCGTCTCGATATCACCATC
GACGGCGCCGACGAGATCAATCCGGCGCTCGACCTGATCAAGGGCGGCGGCGGCGCGCTGTTGCGCGAGAAGATCGTCGC
CAGCGCCTCGAATCGCATGATCGTGATCGCCGACGACAGCAAATGGGTCGCGCGGCTCGGCCGCTTCCCGCTGCCGATCG
AGGTGGTCCCGTTCGGGATCGCGGCCACGCAGCGCGAGATCGCCGACGCCTTCACCAAGGCTGGCGTGGCTGGGCCGATG
AGCTTGCGCAAGTCCGCAGATGGCCACGTTTTCGTCACCGATGGTGGCCACTGGATTGTCGACGTTCGCCTGGGGGAGAT
CGAGGATCCCCCGCGCCTGGCGAGCTTTTTGAGCGCAATTCCGGGCGTGGTCGAGCACGGGCTGTTCATCGGCCTCGGCA
GCACGGCGATCCTGGCAGGCGCACAGGGAATTCGCGTTATCCAGCGGCCTTGA

Upstream 100 bases:

>100_bases
GGCCCCGCGTCAAAACATCGCTAGATATGCGCCGGCTTTCGGCCCCCTTCCCAGGGGCCTCGGCTCCAAGGGGCAGGTTG
GGGGCAGGTTGTTGGTCGAT

Downstream 100 bases:

>100_bases
GCGCAGAAAGACCTGCAACTCAGGGACGCAATCTCACAGGAGACTTGGAATGAAGAGCGTGTTCAGAATCCTGCCGGCCG
CCGGCATCGTGCTGGCGCTG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MDALKRQAAARALEEVESGMKLGLGTGSTAKHFVDLLGEKVRAGLKVVGVPTSEATRAQAEACGVPLTTLDEIDRLDITI
DGADEINPALDLIKGGGGALLREKIVASASNRMIVIADDSKWVARLGRFPLPIEVVPFGIAATQREIADAFTKAGVAGPM
SLRKSADGHVFVTDGGHWIVDVRLGEIEDPPRLASFLSAIPGVVEHGLFIGLGSTAILAGAQGIRVIQRP

Sequences:

>Translated_230_residues
MDALKRQAAARALEEVESGMKLGLGTGSTAKHFVDLLGEKVRAGLKVVGVPTSEATRAQAEACGVPLTTLDEIDRLDITI
DGADEINPALDLIKGGGGALLREKIVASASNRMIVIADDSKWVARLGRFPLPIEVVPFGIAATQREIADAFTKAGVAGPM
SLRKSADGHVFVTDGGHWIVDVRLGEIEDPPRLASFLSAIPGVVEHGLFIGLGSTAILAGAQGIRVIQRP
>Mature_230_residues
MDALKRQAAARALEEVESGMKLGLGTGSTAKHFVDLLGEKVRAGLKVVGVPTSEATRAQAEACGVPLTTLDEIDRLDITI
DGADEINPALDLIKGGGGALLREKIVASASNRMIVIADDSKWVARLGRFPLPIEVVPFGIAATQREIADAFTKAGVAGPM
SLRKSADGHVFVTDGGHWIVDVRLGEIEDPPRLASFLSAIPGVVEHGLFIGLGSTAILAGAQGIRVIQRP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=215, Percent_Identity=38.1395348837209, Blast_Score=121, Evalue=6e-28,
Organism=Escherichia coli, GI1789280, Length=229, Percent_Identity=41.0480349344978, Blast_Score=150, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17551758, Length=229, Percent_Identity=38.4279475982533, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324669, Length=238, Percent_Identity=31.0924369747899, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364072, Length=218, Percent_Identity=34.8623853211009, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24058; Mature: 24058

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALKRQAAARALEEVESGMKLGLGTGSTAKHFVDLLGEKVRAGLKVVGVPTSEATRAQA
CCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
EACGVPLTTLDEIDRLDITIDGADEINPALDLIKGGGGALLREKIVASASNRMIVIADDS
HHCCCCCCCHHCCCEEEEEECCCHHCCHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCC
KWVARLGRFPLPIEVVPFGIAATQREIADAFTKAGVAGPMSLRKSADGHVFVTDGGHWIV
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCEEEE
DVRLGEIEDPPRLASFLSAIPGVVEHGLFIGLGSTAILAGAQGIRVIQRP
EEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEECCC
>Mature Secondary Structure
MDALKRQAAARALEEVESGMKLGLGTGSTAKHFVDLLGEKVRAGLKVVGVPTSEATRAQA
CCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
EACGVPLTTLDEIDRLDITIDGADEINPALDLIKGGGGALLREKIVASASNRMIVIADDS
HHCCCCCCCHHCCCEEEEEECCCHHCCHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCC
KWVARLGRFPLPIEVVPFGIAATQREIADAFTKAGVAGPMSLRKSADGHVFVTDGGHWIV
HHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEEECCCEEEE
DVRLGEIEDPPRLASFLSAIPGVVEHGLFIGLGSTAILAGAQGIRVIQRP
EEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]