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The map label for this gene is mdtA [H]

Identifier: 146341558

GI number: 146341558

Start: 4844824

End: 4846005

Strand: Direct

Name: mdtA [H]

Synonym: BRADO4656

Alternate gene names: 146341558

Gene position: 4844824-4846005 (Clockwise)

Preceding gene: 146341550

Following gene: 146341559

Centisome position: 64.97

GC content: 64.64

Gene sequence:

>1182_bases
ATGTGGGCCAGCATGAAAGCATCACGAACCATCACCTGGATCCTGCTGGTCGCGGCTCTCGGCGGCGCCGGCTATTACGG
CTGGCAGCGTACCCAGGACGCTGAAGCGGCGAAGAAGACCGCCGCGCAGAAGTCCGCCCGGCCACCGGCGGTTCGGGTAT
CGACCGCCCCTGTCGAGAAGATCGATTTCCCCGTCTTCCTCACCGGGCTCGGCACCGTCCAGGGTTTCAATACCGTCCAG
GTCCGCACCCGCGTGGATGGCCAGATCGACAAGATCGCCTTCACCGAGGGACAACTCGTCAACGAAGGCGATCTCCTGGT
CGAGATCGATCCAAGGCCGTTCCAGGCCGCGCTCGATCAGGCCAAGGCCAAGAAGGCCCAGGACGAGGCCAATCTCGCCA
ACGCCAATCTCGATCTGCAACGCTACACCAAGCTCGGCGAGTTCGCGACCCGGCAGCAGCAGGACACCCAGCGCGCAACC
GTCGCGCAGCTGACGGCGCAGATTTCGGCCGACGACGCGGCCATCGCCAATGCCCAGACGCAGCTCAGCTACACCCAGGT
GAAGTCGCCGATCTCGGGGGTCGCCGGTCTGCGCCAGGTCGATATCGGCAACATCGTCAACGCCTCGAGCCAGACCGGCA
TCGTCTCGATCGCGCAGATCGAGCCGATCGCGGTGATCTTCACCGCGCCCGAGGAGCAGCTGCCCTACATCAACGAGGCG
CAGAAGACGGCTCCCTTGAAGGTGATCGCGCTCACCACCGACGGCAAGAAGCAGCTCGCCGAGGGGAAGCTGATGGTCGT
GAACAACCAGGTCGACACGTCGAGCGGAACAATCCGCCTCAAGGCGGTGTTCGACAACAAGGAGCACGTGCTGTGGCCGG
GCCAGTCGGTCTCGACGCGTCTCCTGGTGCGGACGCTGAAGGACGCGACGGTTGTTCCCGACGACGCGGTCCAGCATTCG
ACCAGTGGGCTCTATTCGTACACGGTCAGTCCGGAGAGCAAGGCCGAGCTGCGCAAGGTGAAGGTGGGCGCCTCGATCGA
TGGCCGCACGGTCATTGAGGAGGGTCTCACTCCCGGCCAGCAAGTGATCACCGGCGGTCAGTTCAAGGTACAGCCAGGCT
CGGTCGTGACCACAGCGGTCGCCAGTACGGAGCCGGCGGCAGCGAAGGTCCGGCAGGAATGA

Upstream 100 bases:

>100_bases
TTCGGCCGAGCTGTCGTGTGTTTACACATTAATTGCGAGCATACTATATCTGTGCCGCTGGGAACGGCGTTAAAGACCGG
TTATCCTGTGGCGTCTCAGC

Downstream 100 bases:

>100_bases
ACGGCGGCGGCATCTCGGCACCCTTCATCAAATACCCCATCGGCACCTCGCTGCTGATGGCGGGCATCCTCTTCATCGGC
CTCGTCGCCTATCCGCTGCT

Product: putative component of multidrug efflux pump, mdtA-like

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MWASMKASRTITWILLVAALGGAGYYGWQRTQDAEAAKKTAAQKSARPPAVRVSTAPVEKIDFPVFLTGLGTVQGFNTVQ
VRTRVDGQIDKIAFTEGQLVNEGDLLVEIDPRPFQAALDQAKAKKAQDEANLANANLDLQRYTKLGEFATRQQQDTQRAT
VAQLTAQISADDAAIANAQTQLSYTQVKSPISGVAGLRQVDIGNIVNASSQTGIVSIAQIEPIAVIFTAPEEQLPYINEA
QKTAPLKVIALTTDGKKQLAEGKLMVVNNQVDTSSGTIRLKAVFDNKEHVLWPGQSVSTRLLVRTLKDATVVPDDAVQHS
TSGLYSYTVSPESKAELRKVKVGASIDGRTVIEEGLTPGQQVITGGQFKVQPGSVVTTAVASTEPAAAKVRQE

Sequences:

>Translated_393_residues
MWASMKASRTITWILLVAALGGAGYYGWQRTQDAEAAKKTAAQKSARPPAVRVSTAPVEKIDFPVFLTGLGTVQGFNTVQ
VRTRVDGQIDKIAFTEGQLVNEGDLLVEIDPRPFQAALDQAKAKKAQDEANLANANLDLQRYTKLGEFATRQQQDTQRAT
VAQLTAQISADDAAIANAQTQLSYTQVKSPISGVAGLRQVDIGNIVNASSQTGIVSIAQIEPIAVIFTAPEEQLPYINEA
QKTAPLKVIALTTDGKKQLAEGKLMVVNNQVDTSSGTIRLKAVFDNKEHVLWPGQSVSTRLLVRTLKDATVVPDDAVQHS
TSGLYSYTVSPESKAELRKVKVGASIDGRTVIEEGLTPGQQVITGGQFKVQPGSVVTTAVASTEPAAAKVRQE
>Mature_393_residues
MWASMKASRTITWILLVAALGGAGYYGWQRTQDAEAAKKTAAQKSARPPAVRVSTAPVEKIDFPVFLTGLGTVQGFNTVQ
VRTRVDGQIDKIAFTEGQLVNEGDLLVEIDPRPFQAALDQAKAKKAQDEANLANANLDLQRYTKLGEFATRQQQDTQRAT
VAQLTAQISADDAAIANAQTQLSYTQVKSPISGVAGLRQVDIGNIVNASSQTGIVSIAQIEPIAVIFTAPEEQLPYINEA
QKTAPLKVIALTTDGKKQLAEGKLMVVNNQVDTSSGTIRLKAVFDNKEHVLWPGQSVSTRLLVRTLKDATVVPDDAVQHS
TSGLYSYTVSPESKAELRKVKVGASIDGRTVIEEGLTPGQQVITGGQFKVQPGSVVTTAVASTEPAAAKVRQE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=368, Percent_Identity=38.5869565217391, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1789929, Length=327, Percent_Identity=28.4403669724771, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789665, Length=335, Percent_Identity=32.2388059701493, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786668, Length=345, Percent_Identity=32.1739130434783, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081951, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42034; Mature: 42034

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWASMKASRTITWILLVAALGGAGYYGWQRTQDAEAAKKTAAQKSARPPAVRVSTAPVEK
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHH
IDFPVFLTGLGTVQGFNTVQVRTRVDGQIDKIAFTEGQLVNEGDLLVEIDPRPFQAALDQ
CCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEECCCCEEEEECCCHHHHHHHH
AKAKKAQDEANLANANLDLQRYTKLGEFATRQQQDTQRATVAQLTAQISADDAAIANAQT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHH
QLSYTQVKSPISGVAGLRQVDIGNIVNASSQTGIVSIAQIEPIAVIFTAPEEQLPYINEA
HHHHHHHHCCHHHHCCCEEECCCCEECCCCCCCEEEEEEECEEEEEEECCHHHCCCCCCC
QKTAPLKVIALTTDGKKQLAEGKLMVVNNQVDTSSGTIRLKAVFDNKEHVLWPGQSVSTR
CCCCCEEEEEEECCCHHHHHCCCEEEEECCCCCCCCEEEEEEEECCCCEEEECCCCHHHH
LLVRTLKDATVVPDDAVQHSTSGLYSYTVSPESKAELRKVKVGASIDGRTVIEEGLTPGQ
HHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCHHHHEEEEECCCCCCCHHHHHCCCCCH
QVITGGQFKVQPGSVVTTAVASTEPAAAKVRQE
HHEECCEEEECCCCEEEEEECCCCCHHHHCCCC
>Mature Secondary Structure
MWASMKASRTITWILLVAALGGAGYYGWQRTQDAEAAKKTAAQKSARPPAVRVSTAPVEK
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHH
IDFPVFLTGLGTVQGFNTVQVRTRVDGQIDKIAFTEGQLVNEGDLLVEIDPRPFQAALDQ
CCCCEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEECCCCEEEEECCCHHHHHHHH
AKAKKAQDEANLANANLDLQRYTKLGEFATRQQQDTQRATVAQLTAQISADDAAIANAQT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHH
QLSYTQVKSPISGVAGLRQVDIGNIVNASSQTGIVSIAQIEPIAVIFTAPEEQLPYINEA
HHHHHHHHCCHHHHCCCEEECCCCEECCCCCCCEEEEEEECEEEEEEECCHHHCCCCCCC
QKTAPLKVIALTTDGKKQLAEGKLMVVNNQVDTSSGTIRLKAVFDNKEHVLWPGQSVSTR
CCCCCEEEEEEECCCHHHHHCCCEEEEECCCCCCCCEEEEEEEECCCCEEEECCCCHHHH
LLVRTLKDATVVPDDAVQHSTSGLYSYTVSPESKAELRKVKVGASIDGRTVIEEGLTPGQ
HHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCHHHHEEEEECCCCCCCHHHHHCCCCCH
QVITGGQFKVQPGSVVTTAVASTEPAAAKVRQE
HHEECCEEEECCCCEEEEEECCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]