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The map label for this gene is mntH [H]

Identifier: 146341355

GI number: 146341355

Start: 4640155

End: 4641537

Strand: Reverse

Name: mntH [H]

Synonym: BRADO4439

Alternate gene names: 146341355

Gene position: 4641537-4640155 (Counterclockwise)

Preceding gene: 146341358

Following gene: 146341351

Centisome position: 62.25

GC content: 64.86

Gene sequence:

>1383_bases
ATGGACGCCAAATCGCCAGACCTTTCGCAACTCCATGCCATGGTTTCGCCGGGTGACGGCTTGATGACCGACGGGTGGCG
CAACGCGCGCGGCGAGCCGTCGCTGGGCAACATGTTCGCGTCGGTTCGAACCTCCGCCAAAGGTTCGCTGTGGCGGAAGC
TGATAGCCTTTCTCGGGCCTGGTTATCTCGTGGCCGTGGGCTACATGGACCCCGGCAATTGGGCGACGTCGCTCGCCGGC
GGTTCCAAATTCGGCTACGTGCTGCTCTCCGTCGCGCTGCTCTCCAATCTGATGGCCATCGTGCTGCAGTCGCTATGCAC
CCGGCTGGGTGTCGCAACCGGGCGCGACCTGGCGCAGGCCTGTCGCGACTCGACGCCGCGCTGGGTCTCGGTGCCGTTAT
GGCTGTCTGCGGAGATCGCAATCACTGCGACCGATCTGGCCGAGGTCATCGGCACCGCGATCGGGCTCAGCCTCCTGTTC
GGGCTGCCGCTGTCGATCGGCGTCTGCGTCACCGCGCTCGATGTCTTCCTGATCCTGGCGCTGCAGGCGTTCGGCTTTCG
CTGGATCGAGGCTTTCGTGGTTGCGCTGCTCGGAATCATCGCGCTGTGCTTCGCAATCCAGATCGCGATGGCGCAGCCGG
ACTGGGCGCAGGTGATCAAGGGCTTCGTTCCGAGCGGCCAGCTGATCGCCAATCCCGAAATGCTGTATCTGGCGCTCGGC
ATTCTCGGCGCGACCGTGATGCCGCACAATCTCTATCTCCATTCCGGGCTGGTGCAGACCCGCGGCTATGGCGATAGCCC
GGAGGAGAAGCGCGAGGCGATCACGCTCTCGACGATCGATTCGACGATCGCGTTGTGTCTGGCGCTCACCATCAACGCCT
CGATTCTGATCCTGGCCGCGGCCACATTCCACAAGACCGGACAGCACGACGTCGCCGAGCTCGACCAGGCGCATGCGTTC
CTGGCGCCGCTGCTGGGATCGACGCTCGCGCCGACGCTGTTTGCCATCGCGCTGCTGTGCTGTGGCCTGAACTCGACGAT
CACTGCCACGCTGTCTGGCCAGATCGTGATGGAGGGCTTCCTGCAATGGCGGATCGCGCCGTGGCTGCGCCGCCTGATCA
CGCGGATGATCGCGATCGTGCCAGCCGTTGTCGTGACGATCTGGGCCGGCGAAAAGGCCACCGGACAGCTTCTGATTCTC
AGTCAGGTCGTGCTCAGCCTGCAGCTGCCGTTCGCCGTCGTGCCGCTGGTTCTGATCACGGCGAGCCGCTCGAAGATGGG
CCAGTTCGTGGCGCCGCGCTGGTTGACGGCCATCGCCGGCGCAATCGCCGTGGCGATCATCGTGCTCAACGCCAAGCTGG
TATGGGATCTCGCGGCGGGATGA

Upstream 100 bases:

>100_bases
GGTATGGGAATATTTCCACTGGTCCATGGACGGCATCATTCACACAAGCCGCTTTTGCAAATAAGTTGCATTAAAGGTCG
GCTTCGTTCAGGATGGTGCG

Downstream 100 bases:

>100_bases
AGAGAGGCGGATGGGGAGTAGGGCATAGGAACCGCTACTCGCCCCTTGTCACTCCTGCGGCTCCGGCGCTGGTCCGCCCT
CTGCCTCGACGCGGAGCCAG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MDAKSPDLSQLHAMVSPGDGLMTDGWRNARGEPSLGNMFASVRTSAKGSLWRKLIAFLGPGYLVAVGYMDPGNWATSLAG
GSKFGYVLLSVALLSNLMAIVLQSLCTRLGVATGRDLAQACRDSTPRWVSVPLWLSAEIAITATDLAEVIGTAIGLSLLF
GLPLSIGVCVTALDVFLILALQAFGFRWIEAFVVALLGIIALCFAIQIAMAQPDWAQVIKGFVPSGQLIANPEMLYLALG
ILGATVMPHNLYLHSGLVQTRGYGDSPEEKREAITLSTIDSTIALCLALTINASILILAAATFHKTGQHDVAELDQAHAF
LAPLLGSTLAPTLFAIALLCCGLNSTITATLSGQIVMEGFLQWRIAPWLRRLITRMIAIVPAVVVTIWAGEKATGQLLIL
SQVVLSLQLPFAVVPLVLITASRSKMGQFVAPRWLTAIAGAIAVAIIVLNAKLVWDLAAG

Sequences:

>Translated_460_residues
MDAKSPDLSQLHAMVSPGDGLMTDGWRNARGEPSLGNMFASVRTSAKGSLWRKLIAFLGPGYLVAVGYMDPGNWATSLAG
GSKFGYVLLSVALLSNLMAIVLQSLCTRLGVATGRDLAQACRDSTPRWVSVPLWLSAEIAITATDLAEVIGTAIGLSLLF
GLPLSIGVCVTALDVFLILALQAFGFRWIEAFVVALLGIIALCFAIQIAMAQPDWAQVIKGFVPSGQLIANPEMLYLALG
ILGATVMPHNLYLHSGLVQTRGYGDSPEEKREAITLSTIDSTIALCLALTINASILILAAATFHKTGQHDVAELDQAHAF
LAPLLGSTLAPTLFAIALLCCGLNSTITATLSGQIVMEGFLQWRIAPWLRRLITRMIAIVPAVVVTIWAGEKATGQLLIL
SQVVLSLQLPFAVVPLVLITASRSKMGQFVAPRWLTAIAGAIAVAIIVLNAKLVWDLAAG
>Mature_460_residues
MDAKSPDLSQLHAMVSPGDGLMTDGWRNARGEPSLGNMFASVRTSAKGSLWRKLIAFLGPGYLVAVGYMDPGNWATSLAG
GSKFGYVLLSVALLSNLMAIVLQSLCTRLGVATGRDLAQACRDSTPRWVSVPLWLSAEIAITATDLAEVIGTAIGLSLLF
GLPLSIGVCVTALDVFLILALQAFGFRWIEAFVVALLGIIALCFAIQIAMAQPDWAQVIKGFVPSGQLIANPEMLYLALG
ILGATVMPHNLYLHSGLVQTRGYGDSPEEKREAITLSTIDSTIALCLALTINASILILAAATFHKTGQHDVAELDQAHAF
LAPLLGSTLAPTLFAIALLCCGLNSTITATLSGQIVMEGFLQWRIAPWLRRLITRMIAIVPAVVVTIWAGEKATGQLLIL
SQVVLSLQLPFAVVPLVLITASRSKMGQFVAPRWLTAIAGAIAVAIIVLNAKLVWDLAAG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI295293167, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI109255241, Length=431, Percent_Identity=36.8909512761021, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI295293171, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI295293169, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI295293178, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI295293175, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI295293173, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI10835169, Length=425, Percent_Identity=40, Blast_Score=233, Evalue=3e-61,
Organism=Escherichia coli, GI1788736, Length=408, Percent_Identity=40.6862745098039, Blast_Score=270, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI193210616, Length=445, Percent_Identity=33.2584269662921, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI71999499, Length=438, Percent_Identity=33.3333333333333, Blast_Score=211, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17569473, Length=398, Percent_Identity=33.6683417085427, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71993856, Length=221, Percent_Identity=38.0090497737557, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324450, Length=425, Percent_Identity=40.2352941176471, Blast_Score=289, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6323062, Length=415, Percent_Identity=41.9277108433735, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6321841, Length=417, Percent_Identity=41.4868105515587, Blast_Score=266, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45553443, Length=417, Percent_Identity=34.052757793765, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24648607, Length=417, Percent_Identity=34.052757793765, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI281362176, Length=417, Percent_Identity=34.052757793765, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24648609, Length=417, Percent_Identity=34.052757793765, Blast_Score=222, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 48717; Mature: 48717

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKSPDLSQLHAMVSPGDGLMTDGWRNARGEPSLGNMFASVRTSAKGSLWRKLIAFLGP
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
GYLVAVGYMDPGNWATSLAGGSKFGYVLLSVALLSNLMAIVLQSLCTRLGVATGRDLAQA
CEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
CRDSTPRWVSVPLWLSAEIAITATDLAEVIGTAIGLSLLFGLPLSIGVCVTALDVFLILA
HHCCCCCEEEEEEEEECEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LQAFGFRWIEAFVVALLGIIALCFAIQIAMAQPDWAQVIKGFVPSGQLIANPEMLYLALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCHHHHHHHH
ILGATVMPHNLYLHSGLVQTRGYGDSPEEKREAITLSTIDSTIALCLALTINASILILAA
HHHHHHCCCCCHHCCCHHHCCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHCCHHHEEEH
ATFHKTGQHDVAELDQAHAFLAPLLGSTLAPTLFAIALLCCGLNSTITATLSGQIVMEGF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
LQWRIAPWLRRLITRMIAIVPAVVVTIWAGEKATGQLLILSQVVLSLQLPFAVVPLVLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
ASRSKMGQFVAPRWLTAIAGAIAVAIIVLNAKLVWDLAAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
>Mature Secondary Structure
MDAKSPDLSQLHAMVSPGDGLMTDGWRNARGEPSLGNMFASVRTSAKGSLWRKLIAFLGP
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
GYLVAVGYMDPGNWATSLAGGSKFGYVLLSVALLSNLMAIVLQSLCTRLGVATGRDLAQA
CEEEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
CRDSTPRWVSVPLWLSAEIAITATDLAEVIGTAIGLSLLFGLPLSIGVCVTALDVFLILA
HHCCCCCEEEEEEEEECEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LQAFGFRWIEAFVVALLGIIALCFAIQIAMAQPDWAQVIKGFVPSGQLIANPEMLYLALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCHHHHHHHH
ILGATVMPHNLYLHSGLVQTRGYGDSPEEKREAITLSTIDSTIALCLALTINASILILAA
HHHHHHCCCCCHHCCCHHHCCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHCCHHHEEEH
ATFHKTGQHDVAELDQAHAFLAPLLGSTLAPTLFAIALLCCGLNSTITATLSGQIVMEGF
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
LQWRIAPWLRRLITRMIAIVPAVVVTIWAGEKATGQLLILSQVVLSLQLPFAVVPLVLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
ASRSKMGQFVAPRWLTAIAGAIAVAIIVLNAKLVWDLAAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]