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The map label for this gene is lrp [H]

Identifier: 146340629

GI number: 146340629

Start: 3843939

End: 3844424

Strand: Reverse

Name: lrp [H]

Synonym: BRADO3677

Alternate gene names: 146340629

Gene position: 3844424-3843939 (Counterclockwise)

Preceding gene: 146340630

Following gene: 146340627

Centisome position: 51.56

GC content: 69.14

Gene sequence:

>486_bases
ATGGCGGAGCGGCCCGACGTCGACGTCATCGACCGCAGGATCCTGGCGGAGCTCCAGGCCGACGGCCGCATCCGCATCAA
CGAGCTCGCCGACCGCGTCGGCATCTCGCAGCCGAACTGCCTGCGCCGGGTGCGCGCGCTGCGCGGCAGCGGCGTGATCA
AGGCGATCCGGGCCACCATCGACGAACGGGCGCTGGGCTATGAGGTGGTCTCGTTCGTGACGATTCAGCTCGACAGCCAG
ACCCAGGCGGCCCTGGGGGCTTTCGAGGGGGCGATCAAGCCGTTGCCGTGGGTCCAGCAATGCTGGCGGCTGTCCGGCGA
CGCTGACTTCCTGCTGAAATGCGTGTCGACGGGGGTCGAGGGCATGAGCCGGCAGCTCCGACAATTTGCCGCCCTGCCCG
GCGTCCGCACCATCAGAAGCTTCCCGTCGCTCGGCCAGTCAAAGGACGGACTGCTGCCGATACCGGACGACGGCGCGCCG
GAGTAG

Upstream 100 bases:

>100_bases
CCGCGCATGAGAAGCTCGTGCTGTCCGGCGTCATGCCGCACCGCGTGACCTCGCGACCGAACGGCGCCGGCGGTCCGGCC
GACGCACAGGTCTAGCGGCG

Downstream 100 bases:

>100_bases
AGCGTCGCGTCTGATCAGCTCGTCCAGATCAAAGCGTCGAAGGTTTAGTGCGTCCAAGAATCAGTGCGTCCAAGGCTCGC
CGCGGCGGAACGAGAAGTTG

Product: AsnC/Lrp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAERPDVDVIDRRILAELQADGRIRINELADRVGISQPNCLRRVRALRGSGVIKAIRATIDERALGYEVVSFVTIQLDSQ
TQAALGAFEGAIKPLPWVQQCWRLSGDADFLLKCVSTGVEGMSRQLRQFAALPGVRTIRSFPSLGQSKDGLLPIPDDGAP
E

Sequences:

>Translated_161_residues
MAERPDVDVIDRRILAELQADGRIRINELADRVGISQPNCLRRVRALRGSGVIKAIRATIDERALGYEVVSFVTIQLDSQ
TQAALGAFEGAIKPLPWVQQCWRLSGDADFLLKCVSTGVEGMSRQLRQFAALPGVRTIRSFPSLGQSKDGLLPIPDDGAP
E
>Mature_160_residues
AERPDVDVIDRRILAELQADGRIRINELADRVGISQPNCLRRVRALRGSGVIKAIRATIDERALGYEVVSFVTIQLDSQT
QAALGAFEGAIKPLPWVQQCWRLSGDADFLLKCVSTGVEGMSRQLRQFAALPGVRTIRSFPSLGQSKDGLLPIPDDGAPE

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=152, Percent_Identity=39.4736842105263, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI87081742, Length=146, Percent_Identity=26.7123287671233, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17610; Mature: 17479

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERPDVDVIDRRILAELQADGRIRINELADRVGISQPNCLRRVRALRGSGVIKAIRATI
CCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHH
DERALGYEVVSFVTIQLDSQTQAALGAFEGAIKPLPWVQQCWRLSGDADFLLKCVSTGVE
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GMSRQLRQFAALPGVRTIRSFPSLGQSKDGLLPIPDDGAPE
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure 
AERPDVDVIDRRILAELQADGRIRINELADRVGISQPNCLRRVRALRGSGVIKAIRATI
CCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHH
DERALGYEVVSFVTIQLDSQTQAALGAFEGAIKPLPWVQQCWRLSGDADFLLKCVSTGVE
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
GMSRQLRQFAALPGVRTIRSFPSLGQSKDGLLPIPDDGAPE
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]