Click here to switch to the map view.

The map label for this gene is efp [H]

Identifier: 146340543

GI number: 146340543

Start: 3778648

End: 3779214

Strand: Reverse

Name: efp [H]

Synonym: BRADO3586

Alternate gene names: 146340543

Gene position: 3779214-3778648 (Counterclockwise)

Preceding gene: 146340547

Following gene: 146340542

Centisome position: 50.68

GC content: 62.08

Gene sequence:

>567_bases
TTGAAAGTCATCGCCAGCTCTATTCGCAAGGGTAACGTCATTGAGCAAGACGGCAAGCTTTACGTTGTCGTCAGCGCCGA
GAACATCCATCCCGGCAAGGGCACCCCGGTCAGCCAGATCGAAATGCGCCGAATCAGCGACGGCGTGAAGATCTCCGAGC
GCTACAAGACCACCGACCAGGTCGAGAAGGCCACGATCGAAGAGCGCAACTACACCTACCTGTACGAAGACCAGGACGGC
TTCCACTTCATGAACCCGGAGACCTACGACCAGGTCCAGGTGCCGAAGGACGTCGTCGGCACGCAGGCGGCGTATCTCCA
GGAGAACATGACCGTCAAGCTGTCGATGCACGACACCAACCCCGTCTCGATCGCGCTGCCGCAGCGCGTCACGCTGGAGG
TCGTCGAGACCGAGCCGGTCACCAAGGGCCAGACCGCGTCGTCATCGTACAAGCCGGCCGTGCTCTCCAACGGCGTCCGC
ACCGGCGTGCCGCCGCACATTACCGTCGGCACCCGCATCGTTGTGATGACCGAGGACGGCTCCTATTGCGAGCGCGCCAA
GGACTGA

Upstream 100 bases:

>100_bases
CTCGGACAAAATCAGTATGTTGCGCCCCGAAACCGCACCCGGCGTCCGACCGCCGCCCGGCTCTGCCCGTTGCCGGGCCC
CAAGATCAGGAAAAACAGCT

Downstream 100 bases:

>100_bases
CGCATGATGCAGGCGGAGATGGCATGATCTGACGCCGGGGGGCGCGGGGGATTGGGGGCAAGGATCACCTTTATCACCGC
GGCCCTTGCTGCGGTGATCA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKVIASSIRKGNVIEQDGKLYVVVSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYTYLYEDQDG
FHFMNPETYDQVQVPKDVVGTQAAYLQENMTVKLSMHDTNPVSIALPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVR
TGVPPHITVGTRIVVMTEDGSYCERAKD

Sequences:

>Translated_188_residues
MKVIASSIRKGNVIEQDGKLYVVVSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYTYLYEDQDG
FHFMNPETYDQVQVPKDVVGTQAAYLQENMTVKLSMHDTNPVSIALPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVR
TGVPPHITVGTRIVVMTEDGSYCERAKD
>Mature_188_residues
MKVIASSIRKGNVIEQDGKLYVVVSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEERNYTYLYEDQDG
FHFMNPETYDQVQVPKDVVGTQAAYLQENMTVKLSMHDTNPVSIALPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVR
TGVPPHITVGTRIVVMTEDGSYCERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=35.5191256830601, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=32.620320855615, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20894; Mature: 20894

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIASSIRKGNVIEQDGKLYVVVSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQ
CCCCHHHCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEHHHHCCHHH
VEKATIEERNYTYLYEDQDGFHFMNPETYDQVQVPKDVVGTQAAYLQENMTVKLSMHDTN
HHHHHHCCCCCEEEEECCCCEEECCCCCCCCEECCHHHHCCHHHHCCCCCEEEEEECCCC
PVSIALPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVRTGVPPHITVGTRIVVMTEDG
CEEEEECCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEECCEEEEEECCC
SYCERAKD
CHHHCCCC
>Mature Secondary Structure
MKVIASSIRKGNVIEQDGKLYVVVSAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQ
CCCCHHHCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEHHHHCCHHH
VEKATIEERNYTYLYEDQDGFHFMNPETYDQVQVPKDVVGTQAAYLQENMTVKLSMHDTN
HHHHHHCCCCCEEEEECCCCEEECCCCCCCCEECCHHHHCCHHHHCCCCCEEEEEECCCC
PVSIALPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVRTGVPPHITVGTRIVVMTEDG
CEEEEECCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEECCEEEEEECCC
SYCERAKD
CHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA