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The map label for this gene is pdtaS [H]

Identifier: 146340457

GI number: 146340457

Start: 3679989

End: 3681077

Strand: Reverse

Name: pdtaS [H]

Synonym: BRADO3497

Alternate gene names: 146340457

Gene position: 3681077-3679989 (Counterclockwise)

Preceding gene: 146340458

Following gene: 146340456

Centisome position: 49.37

GC content: 67.77

Gene sequence:

>1089_bases
ATGAGCGCCTCCGCCCCCACGCTGCTGTACATCGAGGACGACGCGGCGCTGGCGCGGCTGGTGGAGCGCGGACTGAAGCG
GCTCGGCATCACGGTGGAGCATGCGCCCGACGGCAGCGCGGGCCTGGAGCGGCTGCAGCGCGGGGGCATCGACGTTGTCG
CGCTCGACCAGCATATGCCGGGTCTCGACGGTCTGGAGACGCTGGAGCGCATCATGGCGCTGCCCGAACCGCCGCCCGTG
GTGTTCGTGACGGCGTCGCAGGATTCCAAGATCGCCGTGACCGCCTTGAAGGCCGGCGCCGCCGACTATCTCGTCAAGGA
CGTCCAAGGCGAGTTCATCCCGCTGCTGCAGGTCGCGGCCGAAGGCGCGCTGCGTCAGGCGCGGCTGCAGCGGGCGCGTG
ACGAGGCCGAGGCCGAGGTCCGTGCCTCGCGCGACCGCTTCGCGGCGCTCGCCGCGGAGCGCGAGGTGCTGCTGCGCGAG
GTTAATCACCGTGTCGGCAATTCGCTGCAGATCATCGCCTCGCTGCTGCATCTGCAGGCCAATTCGAGCACCCAGGACGA
CGTCAAGGCGGCGCTCACCAATGCGATGGGCCGCGTCGCCGCCGTGGCCCAGGTCCACCGCCGGCTCTATACGTCGCAGG
ACCTCAAGAGCGTGATGCTCAACCAGTACCTCGACTCGCTGCTCGACGATCTTCGCAGGTCCGCCGAGGGCAACCGGATG
TCGCGACTGACGTTGAAGGCGGAGCCCGTCGAGATCGATCCGGATCGCGCGGTCGCGATCGGCATCGTGGTCAACGAGCT
GGTCATGAACGCCGTCAAATACGCCTATCCCGACGGTCCCGGCCCGATTCATGTCGAGCTGAAGCTGGAGAACGATGACA
TCGTGCTGTCGATCGCCGACAACGGTGTCGGCCTCAATGCGACCAGCGATCCACGCTCGACCGGCATGGGCCAGCGCATC
GTGAGTGCGATGGCCACCAAGCTCGATGCGACCGTGGAGCCGGACCCGAGCCATAACGGCACCAGGATTGTTGTTCGCTT
CCGCCTCAGCAAGGATGCGCCGAAGCCTGCCGCGGCCGCGGTGGGCTGA

Upstream 100 bases:

>100_bases
GCAACGTCTACATCACCAAGCCGGTCAACTACGAAAGCTTCGCCAACGCCATCCGCCAGCTCGGCCTGTTCTTCTCCGTC
ATCCAGGTTCCGCCCGCCGC

Downstream 100 bases:

>100_bases
GCGGTCTGCGTCCGATGAACCCATCGCGTGCCGGTCGATGTCCTGCTAGACTAGAGGGATGAATTCGCGCGACTCCGCAG
CGTCCGAGATCACGCCCGAG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSASAPTLLYIEDDAALARLVERGLKRLGITVEHAPDGSAGLERLQRGGIDVVALDQHMPGLDGLETLERIMALPEPPPV
VFVTASQDSKIAVTALKAGAADYLVKDVQGEFIPLLQVAAEGALRQARLQRARDEAEAEVRASRDRFAALAAEREVLLRE
VNHRVGNSLQIIASLLHLQANSSTQDDVKAALTNAMGRVAAVAQVHRRLYTSQDLKSVMLNQYLDSLLDDLRRSAEGNRM
SRLTLKAEPVEIDPDRAVAIGIVVNELVMNAVKYAYPDGPGPIHVELKLENDDIVLSIADNGVGLNATSDPRSTGMGQRI
VSAMATKLDATVEPDPSHNGTRIVVRFRLSKDAPKPAAAAVG

Sequences:

>Translated_362_residues
MSASAPTLLYIEDDAALARLVERGLKRLGITVEHAPDGSAGLERLQRGGIDVVALDQHMPGLDGLETLERIMALPEPPPV
VFVTASQDSKIAVTALKAGAADYLVKDVQGEFIPLLQVAAEGALRQARLQRARDEAEAEVRASRDRFAALAAEREVLLRE
VNHRVGNSLQIIASLLHLQANSSTQDDVKAALTNAMGRVAAVAQVHRRLYTSQDLKSVMLNQYLDSLLDDLRRSAEGNRM
SRLTLKAEPVEIDPDRAVAIGIVVNELVMNAVKYAYPDGPGPIHVELKLENDDIVLSIADNGVGLNATSDPRSTGMGQRI
VSAMATKLDATVEPDPSHNGTRIVVRFRLSKDAPKPAAAAVG
>Mature_361_residues
SASAPTLLYIEDDAALARLVERGLKRLGITVEHAPDGSAGLERLQRGGIDVVALDQHMPGLDGLETLERIMALPEPPPVV
FVTASQDSKIAVTALKAGAADYLVKDVQGEFIPLLQVAAEGALRQARLQRARDEAEAEVRASRDRFAALAAEREVLLREV
NHRVGNSLQIIASLLHLQANSSTQDDVKAALTNAMGRVAAVAQVHRRLYTSQDLKSVMLNQYLDSLLDDLRRSAEGNRMS
RLTLKAEPVEIDPDRAVAIGIVVNELVMNAVKYAYPDGPGPIHVELKLENDDIVLSIADNGVGLNATSDPRSTGMGQRIV
SAMATKLDATVEPDPSHNGTRIVVRFRLSKDAPKPAAAAVG

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=102, Percent_Identity=40.1960784313725, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790437, Length=99, Percent_Identity=36.3636363636364, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38882; Mature: 38751

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASAPTLLYIEDDAALARLVERGLKRLGITVEHAPDGSAGLERLQRGGIDVVALDQHMP
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCEEEECCCCC
GLDGLETLERIMALPEPPPVVFVTASQDSKIAVTALKAGAADYLVKDVQGEFIPLLQVAA
CCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHH
EGALRQARLQRARDEAEAEVRASRDRFAALAAEREVLLREVNHRVGNSLQIIASLLHLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NSSTQDDVKAALTNAMGRVAAVAQVHRRLYTSQDLKSVMLNQYLDSLLDDLRRSAEGNRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SRLTLKAEPVEIDPDRAVAIGIVVNELVMNAVKYAYPDGPGPIHVELKLENDDIVLSIAD
EEEEEECCCCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEC
NGVGLNATSDPRSTGMGQRIVSAMATKLDATVEPDPSHNGTRIVVRFRLSKDAPKPAAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
VG
CC
>Mature Secondary Structure 
SASAPTLLYIEDDAALARLVERGLKRLGITVEHAPDGSAGLERLQRGGIDVVALDQHMP
CCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCEEEECCCCC
GLDGLETLERIMALPEPPPVVFVTASQDSKIAVTALKAGAADYLVKDVQGEFIPLLQVAA
CCCHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHCCCHHHHHHHHH
EGALRQARLQRARDEAEAEVRASRDRFAALAAEREVLLREVNHRVGNSLQIIASLLHLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NSSTQDDVKAALTNAMGRVAAVAQVHRRLYTSQDLKSVMLNQYLDSLLDDLRRSAEGNRM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SRLTLKAEPVEIDPDRAVAIGIVVNELVMNAVKYAYPDGPGPIHVELKLENDDIVLSIAD
EEEEEECCCCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEC
NGVGLNATSDPRSTGMGQRIVSAMATKLDATVEPDPSHNGTRIVVRFRLSKDAPKPAAAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
VG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]