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The map label for this gene is glnII [H]

Identifier: 146340367

GI number: 146340367

Start: 3586303

End: 3587376

Strand: Direct

Name: glnII [H]

Synonym: BRADO3395

Alternate gene names: 146340367

Gene position: 3586303-3587376 (Clockwise)

Preceding gene: 146340365

Following gene: 146340368

Centisome position: 48.1

GC content: 62.66

Gene sequence:

>1074_bases
TTGCTGGGCTCCCACCTTTCGATAAGACAGAGAGGCTCAATGACGAAATACAAGCTCGAGTACATCTGGCTCGACGGCTA
CAAGCCGGTGCCGAATTTGCGCGGCAAGACACAGATCAAGGAATTTTCCTCCTTCCCGACCCTGGAACAGCTGCCTCTTT
GGGGCTTCGACGGCTCGTCGACGATGCAGGCCGAAGGCCATAGCTCCGACTGCGTGCTGAAGCCGGTCGCCGTGTATCCC
GACGCCGCCCGCACCAACGGTGTGCTGGTGATGTGCGAAGTCATGATGCCGGACGGCAAGACCCCGCATCCGTCGAACGC
CCGCGCCACCATCCTGGACGATCCGGACGCATGGTTCGGCTTCGAGCAGGAGTACTTCTTCTACAAGGACGGTCGTCCGC
TCGGCTTCCCCGAGTACGGCTATCCGGCTCCGCAGGGCCCGTACTACACCGGCGTCGGCTTCAAGAACGTCGGCGACGTC
GCCCGCAAGATCGTCGAGGAGCATCTCGACCTCTGCCTCGCGGCCGGCATCAACCATGAAGGCATCAACGCCGAGGTGGC
GAAGGGCCAGTGGGAATTCCAGGTGTTCGGCAAGGGCTCGCGTACCGCCGCCGACCAGATGTGGATGGCCCGCTACCTGA
TGCTGCGCCTGACCGAGAAGTACGGCATCGACATCGAGTTCCACTGCAAGCCGCTCGGCGACACCGACTGGAACGGCTCG
GGCATGCACTGCAACTTCTCGACCAAGCACATGCGCGAAGTCGGCGGCAAGGAGTACTTCGAGAAGCTGATGGACGCCTT
CAAGGAAGCCCGCGCCGACCACATCGCCGTGTACGGTCCGGACAACCACATGCGTCTGACCGGCAAGCACGAGACCGCCT
CGATCGACACCTTCAGCTGGGGTGTGGCCGACCGTGGCGCCTCGATCCGCGTGCCGCACTCGTTCGTGAACAATAGCTAC
AAGGGCTATCTGGAAGACCGCCGTCCGAACTCGCAGGGCGACCCCTACCAGATCGCGTCTCAGGTCCTGAAGACGATCTC
GACGGTTCCGACCGGCGCGAAAGCCGCAGCCTAA

Upstream 100 bases:

>100_bases
TTATGCACAATCAGCTGCGGCGGGACGTCGCGGAGTTTGGCACGTTCCATGCTTAAGAGAGCGCTGGCCGATCGTGGCCG
GGTAAGCGGGGAGCCTTCGA

Downstream 100 bases:

>100_bases
GACGCCGAACACAACACCCCGGGGCAGGGGCTGACGTGATGATCCGCCGGAGCAACCGCTCCGGCGGATCATTCGTTTGG
GAGCCCGCTTCGTCTGCGCG

Product: glutamine synthetase II

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLGSHLSIRQRGSMTKYKLEYIWLDGYKPVPNLRGKTQIKEFSSFPTLEQLPLWGFDGSSTMQAEGHSSDCVLKPVAVYP
DAARTNGVLVMCEVMMPDGKTPHPSNARATILDDPDAWFGFEQEYFFYKDGRPLGFPEYGYPAPQGPYYTGVGFKNVGDV
ARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQVFGKGSRTAADQMWMARYLMLRLTEKYGIDIEFHCKPLGDTDWNGS
GMHCNFSTKHMREVGGKEYFEKLMDAFKEARADHIAVYGPDNHMRLTGKHETASIDTFSWGVADRGASIRVPHSFVNNSY
KGYLEDRRPNSQGDPYQIASQVLKTISTVPTGAKAAA

Sequences:

>Translated_357_residues
MLGSHLSIRQRGSMTKYKLEYIWLDGYKPVPNLRGKTQIKEFSSFPTLEQLPLWGFDGSSTMQAEGHSSDCVLKPVAVYP
DAARTNGVLVMCEVMMPDGKTPHPSNARATILDDPDAWFGFEQEYFFYKDGRPLGFPEYGYPAPQGPYYTGVGFKNVGDV
ARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQVFGKGSRTAADQMWMARYLMLRLTEKYGIDIEFHCKPLGDTDWNGS
GMHCNFSTKHMREVGGKEYFEKLMDAFKEARADHIAVYGPDNHMRLTGKHETASIDTFSWGVADRGASIRVPHSFVNNSY
KGYLEDRRPNSQGDPYQIASQVLKTISTVPTGAKAAA
>Mature_357_residues
MLGSHLSIRQRGSMTKYKLEYIWLDGYKPVPNLRGKTQIKEFSSFPTLEQLPLWGFDGSSTMQAEGHSSDCVLKPVAVYP
DAARTNGVLVMCEVMMPDGKTPHPSNARATILDDPDAWFGFEQEYFFYKDGRPLGFPEYGYPAPQGPYYTGVGFKNVGDV
ARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQVFGKGSRTAADQMWMARYLMLRLTEKYGIDIEFHCKPLGDTDWNGS
GMHCNFSTKHMREVGGKEYFEKLMDAFKEARADHIAVYGPDNHMRLTGKHETASIDTFSWGVADRGASIRVPHSFVNNSY
KGYLEDRRPNSQGDPYQIASQVLKTISTVPTGAKAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=349, Percent_Identity=42.1203438395415, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI74271837, Length=349, Percent_Identity=42.1203438395415, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI19923206, Length=349, Percent_Identity=42.1203438395415, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI115532980, Length=359, Percent_Identity=46.7966573816156, Blast_Score=289, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI115532978, Length=359, Percent_Identity=46.7966573816156, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17554028, Length=346, Percent_Identity=45.0867052023121, Blast_Score=271, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17540008, Length=345, Percent_Identity=44.0579710144928, Blast_Score=271, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17538856, Length=346, Percent_Identity=42.7745664739884, Blast_Score=264, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17551038, Length=317, Percent_Identity=39.4321766561514, Blast_Score=212, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6325292, Length=355, Percent_Identity=47.3239436619718, Blast_Score=296, Evalue=5e-81,
Organism=Drosophila melanogaster, GI281360453, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17136208, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24580558, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24641292, Length=359, Percent_Identity=45.6824512534819, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24641290, Length=359, Percent_Identity=45.6824512534819, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI45554830, Length=268, Percent_Identity=48.5074626865672, Blast_Score=231, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 39935; Mature: 39935

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSHLSIRQRGSMTKYKLEYIWLDGYKPVPNLRGKTQIKEFSSFPTLEQLPLWGFDGSS
CCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHCEEECCCCCC
TMQAEGHSSDCVLKPVAVYPDAARTNGVLVMCEVMMPDGKTPHPSNARATILDDPDAWFG
EEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHCC
FEQEYFFYKDGRPLGFPEYGYPAPQGPYYTGVGFKNVGDVARKIVEEHLDLCLAAGINHE
CCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GINAEVAKGQWEFQVFGKGSRTAADQMWMARYLMLRLTEKYGIDIEFHCKPLGDTDWNGS
CCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
GMHCNFSTKHMREVGGKEYFEKLMDAFKEARADHIAVYGPDNHMRLTGKHETASIDTFSW
CEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCEECEEEC
GVADRGASIRVPHSFVNNSYKGYLEDRRPNSQGDPYQIASQVLKTISTVPTGAKAAA
CCCCCCCEEECCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLGSHLSIRQRGSMTKYKLEYIWLDGYKPVPNLRGKTQIKEFSSFPTLEQLPLWGFDGSS
CCCCCCCHHHCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHCEEECCCCCC
TMQAEGHSSDCVLKPVAVYPDAARTNGVLVMCEVMMPDGKTPHPSNARATILDDPDAWFG
EEEECCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCHHCC
FEQEYFFYKDGRPLGFPEYGYPAPQGPYYTGVGFKNVGDVARKIVEEHLDLCLAAGINHE
CCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GINAEVAKGQWEFQVFGKGSRTAADQMWMARYLMLRLTEKYGIDIEFHCKPLGDTDWNGS
CCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
GMHCNFSTKHMREVGGKEYFEKLMDAFKEARADHIAVYGPDNHMRLTGKHETASIDTFSW
CEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCEECEEEC
GVADRGASIRVPHSFVNNSYKGYLEDRRPNSQGDPYQIASQVLKTISTVPTGAKAAA
CCCCCCCEEECCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]