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The map label for this gene is fabD [H]

Identifier: 146340287

GI number: 146340287

Start: 3504799

End: 3505758

Strand: Direct

Name: fabD [H]

Synonym: BRADO3310

Alternate gene names: 146340287

Gene position: 3504799-3505758 (Clockwise)

Preceding gene: 146340282

Following gene: 146340288

Centisome position: 47.0

GC content: 69.17

Gene sequence:

>960_bases
ATGACGGCAGCATTCACTTTTCCGGGGCAGGGGTCCCAGGCCGTCGGCATGGGCAAGGCGCTCGCGGACGCGTTTCCGGC
CGCCCGCGCGGTGTTCGATGAGGTCGACGCGGCGCTCGGCGAAAAGCTGACCACGATCATCTGGGAAGGCCCGGCCGAAA
CCCTGCAGCTCACCGAGAACGCCCAGCCCGCGCTGATGGCGGTCTCGATGGCGACGTTGCGGGTGCTCGAGGCCGAAGCC
GGTTTTTCGGTCGGCCAGGACGCGGCCTTCGTCGCCGGTCATTCGCTCGGCGAATATTCGGCGCTGGCCGCCGCCGGAAG
CCTGACGATTGCCGATACCGCCCGTCTGCTGCGCACCCGAGGGCTGGCCATGCAGAAGGCCGTTCCGGTCGGGGTCGGCG
CGATGGCAGCGCTGCTCGGCATGGATTACGAGGCTGCGGTGGCCGTGGCCGAAGAGGCAGCCCAGGGCGAGGTCTGCCAG
GCCGCCAATGACAATGGCGGTGGCCAGGTGGTGGTGTCCGGCAACAAGGCTGCCGTGGACCGCGCCGTCGAGATCGCCCG
CGCCAAGGGCGCCAAGCGCGCCATGCTGCTGCCCGTCTCCGCGCCCTTCCATTGCCAGCTGATGCAGCCGGCGGCTGACG
TCATGGCTGACGCGCTGTCGAAGGTGACCATCAAGGCGCCAGCCGCGCCTGTCGTGTCGAATGTTCTGGCCGCGCCGATC
ACCGATCCCGACGAGATTCGCCGCCGCCTGGTCGAGCAGGTCACCGGCACGGTGCGCTGGCGCGAATCGATCGCCTATAT
GGCGGGTCAGGGCGTCACCCGTTTCTTCGAGATCGGTGCCGGCAAGGTGTTGAGCGGCCTGGTCAAGCGAATCGCGGATG
GCGCGGTCGGCGTCGCGGTCGGCGGACCGGCCGACATTGCGGTCGCCAAGGATGCGCTGGCCGCGGCGAAGGCATCGTAA

Upstream 100 bases:

>100_bases
GAAATGCGCCCGTCACGCGCTTGACATGGCAGGCCCGGCCAGTGTCTTTCCGGCCAAAGTTACGCATTTCCAGGGATTTT
GGAACGTTCAGGGAGCGGCC

Downstream 100 bases:

>100_bases
GGCGCCGCGTCTGCGGCAGTGAGGAGAGTTGAGATGTTCGATCTGAGTGGCAGGACCGCGCTGGTCACCGGCGCGACCGG
CGGCATCGGCAATGCGATTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTAAFTFPGQGSQAVGMGKALADAFPAARAVFDEVDAALGEKLTTIIWEGPAETLQLTENAQPALMAVSMATLRVLEAEA
GFSVGQDAAFVAGHSLGEYSALAAAGSLTIADTARLLRTRGLAMQKAVPVGVGAMAALLGMDYEAAVAVAEEAAQGEVCQ
AANDNGGGQVVVSGNKAAVDRAVEIARAKGAKRAMLLPVSAPFHCQLMQPAADVMADALSKVTIKAPAAPVVSNVLAAPI
TDPDEIRRRLVEQVTGTVRWRESIAYMAGQGVTRFFEIGAGKVLSGLVKRIADGAVGVAVGGPADIAVAKDALAAAKAS

Sequences:

>Translated_319_residues
MTAAFTFPGQGSQAVGMGKALADAFPAARAVFDEVDAALGEKLTTIIWEGPAETLQLTENAQPALMAVSMATLRVLEAEA
GFSVGQDAAFVAGHSLGEYSALAAAGSLTIADTARLLRTRGLAMQKAVPVGVGAMAALLGMDYEAAVAVAEEAAQGEVCQ
AANDNGGGQVVVSGNKAAVDRAVEIARAKGAKRAMLLPVSAPFHCQLMQPAADVMADALSKVTIKAPAAPVVSNVLAAPI
TDPDEIRRRLVEQVTGTVRWRESIAYMAGQGVTRFFEIGAGKVLSGLVKRIADGAVGVAVGGPADIAVAKDALAAAKAS
>Mature_318_residues
TAAFTFPGQGSQAVGMGKALADAFPAARAVFDEVDAALGEKLTTIIWEGPAETLQLTENAQPALMAVSMATLRVLEAEAG
FSVGQDAAFVAGHSLGEYSALAAAGSLTIADTARLLRTRGLAMQKAVPVGVGAMAALLGMDYEAAVAVAEEAAQGEVCQA
ANDNGGGQVVVSGNKAAVDRAVEIARAKGAKRAMLLPVSAPFHCQLMQPAADVMADALSKVTIKAPAAPVVSNVLAAPIT
DPDEIRRRLVEQVTGTVRWRESIAYMAGQGVTRFFEIGAGKVLSGLVKRIADGAVGVAVGGPADIAVAKDALAAAKAS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=300, Percent_Identity=31.6666666666667, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=48.6928104575163, Blast_Score=257, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI71984332, Length=290, Percent_Identity=31.3793103448276, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=29.553264604811, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=35.4304635761589, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32337; Mature: 32206

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAFTFPGQGSQAVGMGKALADAFPAARAVFDEVDAALGEKLTTIIWEGPAETLQLTEN
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHEEECCC
AQPALMAVSMATLRVLEAEAGFSVGQDAAFVAGHSLGEYSALAAAGSLTIADTARLLRTR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHH
GLAMQKAVPVGVGAMAALLGMDYEAAVAVAEEAAQGEVCQAANDNGGGQVVVSGNKAAVD
CCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCHHHHH
RAVEIARAKGAKRAMLLPVSAPFHCQLMQPAADVMADALSKVTIKAPAAPVVSNVLAAPI
HHHHHHHHCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHEEEECCCHHHHHHHHHCCC
TDPDEIRRRLVEQVTGTVRWRESIAYMAGQGVTRFFEIGAGKVLSGLVKRIADGAVGVAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEEE
GGPADIAVAKDALAAAKAS
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAAFTFPGQGSQAVGMGKALADAFPAARAVFDEVDAALGEKLTTIIWEGPAETLQLTEN
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHEEECCC
AQPALMAVSMATLRVLEAEAGFSVGQDAAFVAGHSLGEYSALAAAGSLTIADTARLLRTR
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHCCCEEHHHHHHHHHHH
GLAMQKAVPVGVGAMAALLGMDYEAAVAVAEEAAQGEVCQAANDNGGGQVVVSGNKAAVD
CCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCHHHHH
RAVEIARAKGAKRAMLLPVSAPFHCQLMQPAADVMADALSKVTIKAPAAPVVSNVLAAPI
HHHHHHHHCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHEEEECCCHHHHHHHHHCCC
TDPDEIRRRLVEQVTGTVRWRESIAYMAGQGVTRFFEIGAGKVLSGLVKRIADGAVGVAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCEEEEE
GGPADIAVAKDALAAAKAS
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]