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The map label for this gene is blh [H]

Identifier: 146340180

GI number: 146340180

Start: 3396591

End: 3397478

Strand: Reverse

Name: blh [H]

Synonym: BRADO3196

Alternate gene names: 146340180

Gene position: 3397478-3396591 (Counterclockwise)

Preceding gene: 146340181

Following gene: 146340179

Centisome position: 45.56

GC content: 63.96

Gene sequence:

>888_bases
ATGTCCTATCCGAGCGATCTCCGTGTGCGGCCCAAGGTGGCCGGCTTCTTCGATCCGGACACCAGCACGATCAGCTATGT
GGTGAAGGATCCGTCATCGCCGTCCTGTGCGATCATCGATCCCGTCCTCGACATCGACTATGCGGCCGGCCGCCTCGGCA
CCCGCTCCGCAGACACGCTGATCGACTATGTCAGGATGAACGATCTGCGGCCGGAATGGCTGATCGAGACGCATGCCCAT
GCCGATCATCTCTCGGCCGCGCCCTACATCCAGGACAAGCTCGGCGGCAAGATCGGCATCGGCGAGCACATCCTCACTGT
GCAGGAGACATTCGGCAAGGTCTTCAACGAAGGCACCGAGTTTCGCCGCGACGGCAGCCAGTTCGACCGGCTGTTCAAGG
ACGGCGACACCTATAAGGTCGGGCAGATGACCGCCTTCACGATGCACACGCCCGGCCACACGCCGGCCTGCGCAACGCAT
GTGATGGGCGATGCGGCGTTTGTTGGCGACACCCTGTTCATGCCCGACGGCGGCACGGCGCGGGCGGATTTTCCCGGCGG
CGATGCGCGCACGCTGTTTCGGTCGATCCGCCGGATCCTCGAGACGCTGCCGCGCGAGACCCGGCTGTTCATGTGTCACG
ATTACGGCCCTGATGGCCGTGAGGTGCGCTGGGAGACGACCGTCGGCGACGAACGCCTTCACAACATTCACGTCCGCGAC
GGCATGACCGAGGACGCGTTCGTTGCGCTGCGCGAGTCCCGCGACAAGATGCTGGGCATGCCGCGGCTGATCATTCCCTC
GCTGCAGGTGAACATCCGCGCTGGACATCTTCCGCCCGCCGACGACAGCGGAAAGACCTTTCTCAAGGTGCCGATCAACG
TGCTGTGA

Upstream 100 bases:

>100_bases
CCTGCGGGACGAAGTCGAGCCCGACGTCTTAGACCCGGCAGAATGACAGAGGGCACGGGGCGGCGATGCCGCCCCGGAGC
TTCATCGTGGAGCAGCAGCC

Downstream 100 bases:

>100_bases
CGATGACGCCGGCAGCATCTTGGTTGCCAGATCACAGCGTCACGAAGATGTCAGTTGCCAAAGACGAGCGCTCCGCGCGA
CCTGTCTGCGGTGAAGAAGA

Product: metallo-hydrolase/oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSYPSDLRVRPKVAGFFDPDTSTISYVVKDPSSPSCAIIDPVLDIDYAAGRLGTRSADTLIDYVRMNDLRPEWLIETHAH
ADHLSAAPYIQDKLGGKIGIGEHILTVQETFGKVFNEGTEFRRDGSQFDRLFKDGDTYKVGQMTAFTMHTPGHTPACATH
VMGDAAFVGDTLFMPDGGTARADFPGGDARTLFRSIRRILETLPRETRLFMCHDYGPDGREVRWETTVGDERLHNIHVRD
GMTEDAFVALRESRDKMLGMPRLIIPSLQVNIRAGHLPPADDSGKTFLKVPINVL

Sequences:

>Translated_295_residues
MSYPSDLRVRPKVAGFFDPDTSTISYVVKDPSSPSCAIIDPVLDIDYAAGRLGTRSADTLIDYVRMNDLRPEWLIETHAH
ADHLSAAPYIQDKLGGKIGIGEHILTVQETFGKVFNEGTEFRRDGSQFDRLFKDGDTYKVGQMTAFTMHTPGHTPACATH
VMGDAAFVGDTLFMPDGGTARADFPGGDARTLFRSIRRILETLPRETRLFMCHDYGPDGREVRWETTVGDERLHNIHVRD
GMTEDAFVALRESRDKMLGMPRLIIPSLQVNIRAGHLPPADDSGKTFLKVPINVL
>Mature_294_residues
SYPSDLRVRPKVAGFFDPDTSTISYVVKDPSSPSCAIIDPVLDIDYAAGRLGTRSADTLIDYVRMNDLRPEWLIETHAHA
DHLSAAPYIQDKLGGKIGIGEHILTVQETFGKVFNEGTEFRRDGSQFDRLFKDGDTYKVGQMTAFTMHTPGHTPACATHV
MGDAAFVGDTLFMPDGGTARADFPGGDARTLFRSIRRILETLPRETRLFMCHDYGPDGREVRWETTVGDERLHNIHVRDG
MTEDAFVALRESRDKMLGMPRLIIPSLQVNIRAGHLPPADDSGKTFLKVPINVL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787158, Length=175, Percent_Identity=32, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538952, Length=257, Percent_Identity=27.2373540856031, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330176, Length=262, Percent_Identity=28.2442748091603, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32805; Mature: 32673

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYPSDLRVRPKVAGFFDPDTSTISYVVKDPSSPSCAIIDPVLDIDYAAGRLGTRSADTL
CCCCCCCEECCCCCEEECCCCCEEEEEEECCCCCCEEEECCHHCCCHHCCCCCCCHHHHH
IDYVRMNDLRPEWLIETHAHADHLSAAPYIQDKLGGKIGIGEHILTVQETFGKVFNEGTE
HHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCHH
FRRDGSQFDRLFKDGDTYKVGQMTAFTMHTPGHTPACATHVMGDAAFVGDTLFMPDGGTA
HHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHHHHHCCHHHCCCEEECCCCCCE
RADFPGGDARTLFRSIRRILETLPRETRLFMCHDYGPDGREVRWETTVGDERLHNIHVRD
ECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCHHHEEEEECC
GMTEDAFVALRESRDKMLGMPRLIIPSLQVNIRAGHLPPADDSGKTFLKVPINVL
CCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SYPSDLRVRPKVAGFFDPDTSTISYVVKDPSSPSCAIIDPVLDIDYAAGRLGTRSADTL
CCCCCCEECCCCCEEECCCCCEEEEEEECCCCCCEEEECCHHCCCHHCCCCCCCHHHHH
IDYVRMNDLRPEWLIETHAHADHLSAAPYIQDKLGGKIGIGEHILTVQETFGKVFNEGTE
HHHHHHCCCCHHHEEECCCCCCCCCCCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCHH
FRRDGSQFDRLFKDGDTYKVGQMTAFTMHTPGHTPACATHVMGDAAFVGDTLFMPDGGTA
HHCCHHHHHHHHHCCCCEEECCEEEEEEECCCCCCHHHHHHHCCHHHCCCEEECCCCCCE
RADFPGGDARTLFRSIRRILETLPRETRLFMCHDYGPDGREVRWETTVGDERLHNIHVRD
ECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCCCHHHEEEEECC
GMTEDAFVALRESRDKMLGMPRLIIPSLQVNIRAGHLPPADDSGKTFLKVPINVL
CCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]