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The map label for this gene is dsbD [H]

Identifier: 146340178

GI number: 146340178

Start: 3393842

End: 3395938

Strand: Reverse

Name: dsbD [H]

Synonym: BRADO3194

Alternate gene names: 146340178

Gene position: 3395938-3393842 (Counterclockwise)

Preceding gene: 146340179

Following gene: 146340177

Centisome position: 45.54

GC content: 68.91

Gene sequence:

>2097_bases
ATGTCCATCCGCCATCCTCGCTGGCTCGGCCTGCTGCTGGGCGCGCTCCTTGTTGCGACGACGGCCGCGAGCGCCGCGTC
GCGGCCTCAGCCGAACCTCGCCACGCGCCTGCTGGTCGGCCACGTCGCACGCACCGACAGCGGCGTGACGACGGCCTGGG
CTGGCCTCGACGTCAGGCTCGGCGCCGGCTGGCACACCTATTGGCGCTCGGCCGGCGACGCGGGTGCGCCACCCGAGTTC
GACTGGGCCGGATCCGCCAATGTCGCTGATGTCACGGTCGAATGGCCGGCGCCGCGCCGCTTCAGCGAGCAGGACATCGA
CACGTTCGGCTATGACGAGCACGTGCTGTTTCCATTGCGGGTGCGGCTGCAGGATGGAGCAGCGCCGGCGTATCTCAAGC
TGAAGGCGGTCCTGTTCGTCTGCTCGATTATCTGCACCCAACAGGAGACACAGCTCGAGGCCGACATCCCGGCGGCCTCA
CATCAGCCGAACGATCAGGCGCTGATCGAGGAATGGCGGCAGAGCGTGCCGCGCGAGACCGCACCCGGCCTCTCCGTCAC
CGCGCTGCGCATCGAACGCCAACCCAAACCGCAGCTGCGTCTCGAGGCCCTGGCGACGCCGCCGCTGCGCGCGCCCGACG
TCTTCGTCGACGGCAGTGAGGCGGTGTCCGGCGGTCGCGCCCAGGTTAGCAACAGCTCGGATGGTGCCGTCACGATCCAT
GTGCCGTTGCAGGGCCTCGATCAGGCTGCGGCTGGAGAACGTCTGCGGGTCACGCTGGTCGATGGTGACAGAGCGATCGA
AGCCACGCTCCCCGTGGACGCTCATACTGTCGCCGCCACGTCGGCAACGATAAGGCCGCACGCCGCTGCGGCATCGATCT
GGACCATCCTCGGCGTGGCGCTGCTCGGCGGATTCATCCTCAACTTCATGCCCTGCGTGTTCCCGGTGCTGTCGCTGAAG
CTCGTCTCCCTGGTGGATCACGATCCGGCCCGCGCGCCGTCACGGCGTCCGGCCTTCCTGGCGACGGCCGCCGGCATCAT
CGCCTCATTCGTGACCCTCGCCCTCGTCCTCTCAAGCCTCAAGGCCGCGGGCGCGGAAGTCGGCTGGGGACTGCAGTTCC
AGCAGCCGGCTTTCCTCATAGCGATGATCGTCGTGCTCGCCGCGTTCGGCGCCAACCTGCTCGGCCTGTTCGAGATCCAA
CTGCCTTGGTGGATCGCCGGCCGCCTCGGCGGCGCCACCGGCCGCAACACGATGGCGGGCCACGCCGTCAACGGCTTCGT
CATGACGCTGCTCGCGACGCCCTGCTCGGCGCCGTTCGTCGGCACCGCCGTGGCGTTCGCGCTGTCGCAAGCTGCGCCGC
AGATCCTGCTGGTGTTCACCGCGCTAGGGCTCGGCATGGCGGCGCCCTATCTGGGCCTCGCAGCGGCGCCGCGCTTGGCC
GCGCTGTTTCCTCGGCCGGGCCGCTGGATGTTGACGCTGCGCGCCGTTGCGGCGCTCGCGATGATCGCAACGGCATCATG
GCTGCTGCGCGTGCTCGCGGACATCAGCGGCGTTGCAGCCGCGGCCATGCTCGCCGCCGTCCTGCTCGTGCCCGCGCTGA
TCCTGACGATGCTGCGCTTTCCGTTGCGGCGAACGGTCGCCGGCGCGGGCGTCATCGTCGCGATCGGGCTGGTGCTGACC
GCCGCCACTGCGATCCGGCACTCGGATGGCCCCGGACGGTCGGACGGAATTGCATGGCGGCCGCTGGTGCCGACAGACAT
CGCGACCCAGGTCAGCGCCGGCCATACTGTGTTCGTCGACATCGGCGCCAGTTGGTGCGTGACCTGCAAGGTCAATGAGA
AGCTCGTGATCGACAGCACCGCCGTGCGAAGCCGTCTCACGTCGGTCGTCACCGTCAGGGCGGACTGGACCTCGCACGAC
GATACGATCGCAGCGTACCTGCAATCCTTCGGCCGCTACGGCCTGCCGTTCAACGTCGTGTTCGGCCCCGGCGCGCCCGC
CGGCATCGTGCTGCCCGAACTGCTCACACCGCAGATCGTGCTCGACGCCATCGACACCGCATCGACCATCCCGCCAAAGG
AGACCGACAAGACATGA

Upstream 100 bases:

>100_bases
CGAACGGATCGAGCACCGCGGCCCCGTTGTTCGGCCGCCTTGCGTCGAACCGCGCGGCACGACCGCTTGAGACATGCGCT
GACCGCGCAGGGAGATCATC

Downstream 100 bases:

>100_bases
TGACCAGGAAGACCTTTGCCGCATCGCTCGCGACGCTGCTGCTGCTCACGGCTGCCATGCTGCCGTTCCAGGCCCGCGCC
GAGGATGACGACGGCGACAT

Product: putative suppressor for copper-sensitivity B protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSIRHPRWLGLLLGALLVATTAASAASRPQPNLATRLLVGHVARTDSGVTTAWAGLDVRLGAGWHTYWRSAGDAGAPPEF
DWAGSANVADVTVEWPAPRRFSEQDIDTFGYDEHVLFPLRVRLQDGAAPAYLKLKAVLFVCSIICTQQETQLEADIPAAS
HQPNDQALIEEWRQSVPRETAPGLSVTALRIERQPKPQLRLEALATPPLRAPDVFVDGSEAVSGGRAQVSNSSDGAVTIH
VPLQGLDQAAAGERLRVTLVDGDRAIEATLPVDAHTVAATSATIRPHAAAASIWTILGVALLGGFILNFMPCVFPVLSLK
LVSLVDHDPARAPSRRPAFLATAAGIIASFVTLALVLSSLKAAGAEVGWGLQFQQPAFLIAMIVVLAAFGANLLGLFEIQ
LPWWIAGRLGGATGRNTMAGHAVNGFVMTLLATPCSAPFVGTAVAFALSQAAPQILLVFTALGLGMAAPYLGLAAAPRLA
ALFPRPGRWMLTLRAVAALAMIATASWLLRVLADISGVAAAAMLAAVLLVPALILTMLRFPLRRTVAGAGVIVAIGLVLT
AATAIRHSDGPGRSDGIAWRPLVPTDIATQVSAGHTVFVDIGASWCVTCKVNEKLVIDSTAVRSRLTSVVTVRADWTSHD
DTIAAYLQSFGRYGLPFNVVFGPGAPAGIVLPELLTPQIVLDAIDTASTIPPKETDKT

Sequences:

>Translated_698_residues
MSIRHPRWLGLLLGALLVATTAASAASRPQPNLATRLLVGHVARTDSGVTTAWAGLDVRLGAGWHTYWRSAGDAGAPPEF
DWAGSANVADVTVEWPAPRRFSEQDIDTFGYDEHVLFPLRVRLQDGAAPAYLKLKAVLFVCSIICTQQETQLEADIPAAS
HQPNDQALIEEWRQSVPRETAPGLSVTALRIERQPKPQLRLEALATPPLRAPDVFVDGSEAVSGGRAQVSNSSDGAVTIH
VPLQGLDQAAAGERLRVTLVDGDRAIEATLPVDAHTVAATSATIRPHAAAASIWTILGVALLGGFILNFMPCVFPVLSLK
LVSLVDHDPARAPSRRPAFLATAAGIIASFVTLALVLSSLKAAGAEVGWGLQFQQPAFLIAMIVVLAAFGANLLGLFEIQ
LPWWIAGRLGGATGRNTMAGHAVNGFVMTLLATPCSAPFVGTAVAFALSQAAPQILLVFTALGLGMAAPYLGLAAAPRLA
ALFPRPGRWMLTLRAVAALAMIATASWLLRVLADISGVAAAAMLAAVLLVPALILTMLRFPLRRTVAGAGVIVAIGLVLT
AATAIRHSDGPGRSDGIAWRPLVPTDIATQVSAGHTVFVDIGASWCVTCKVNEKLVIDSTAVRSRLTSVVTVRADWTSHD
DTIAAYLQSFGRYGLPFNVVFGPGAPAGIVLPELLTPQIVLDAIDTASTIPPKETDKT
>Mature_697_residues
SIRHPRWLGLLLGALLVATTAASAASRPQPNLATRLLVGHVARTDSGVTTAWAGLDVRLGAGWHTYWRSAGDAGAPPEFD
WAGSANVADVTVEWPAPRRFSEQDIDTFGYDEHVLFPLRVRLQDGAAPAYLKLKAVLFVCSIICTQQETQLEADIPAASH
QPNDQALIEEWRQSVPRETAPGLSVTALRIERQPKPQLRLEALATPPLRAPDVFVDGSEAVSGGRAQVSNSSDGAVTIHV
PLQGLDQAAAGERLRVTLVDGDRAIEATLPVDAHTVAATSATIRPHAAAASIWTILGVALLGGFILNFMPCVFPVLSLKL
VSLVDHDPARAPSRRPAFLATAAGIIASFVTLALVLSSLKAAGAEVGWGLQFQQPAFLIAMIVVLAAFGANLLGLFEIQL
PWWIAGRLGGATGRNTMAGHAVNGFVMTLLATPCSAPFVGTAVAFALSQAAPQILLVFTALGLGMAAPYLGLAAAPRLAA
LFPRPGRWMLTLRAVAALAMIATASWLLRVLADISGVAAAAMLAAVLLVPALILTMLRFPLRRTVAGAGVIVAIGLVLTA
ATAIRHSDGPGRSDGIAWRPLVPTDIATQVSAGHTVFVDIGASWCVTCKVNEKLVIDSTAVRSRLTSVVTVRADWTSHDD
TIAAYLQSFGRYGLPFNVVFGPGAPAGIVLPELLTPQIVLDAIDTASTIPPKETDKT

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=387, Percent_Identity=25.8397932816537, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 73328; Mature: 73197

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRHPRWLGLLLGALLVATTAASAASRPQPNLATRLLVGHVARTDSGVTTAWAGLDVRL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEE
GAGWHTYWRSAGDAGAPPEFDWAGSANVADVTVEWPAPRRFSEQDIDTFGYDEHVLFPLR
CCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEE
VRLQDGAAPAYLKLKAVLFVCSIICTQQETQLEADIPAASHQPNDQALIEEWRQSVPRET
EEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
APGLSVTALRIERQPKPQLRLEALATPPLRAPDVFVDGSEAVSGGRAQVSNSSDGAVTIH
CCCCEEEEEEECCCCCCCEEHHEECCCCCCCCCEEECCHHHCCCCCEEECCCCCCEEEEE
VPLQGLDQAAAGERLRVTLVDGDRAIEATLPVDAHTVAATSATIRPHAAAASIWTILGVA
EECCCCCHHCCCCEEEEEEECCCCEEEEECCCCCHHEEECCCCCCCCHHHHHHHHHHHHH
LLGGFILNFMPCVFPVLSLKLVSLVDHDPARAPSRRPAFLATAAGIIASFVTLALVLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KAAGAEVGWGLQFQQPAFLIAMIVVLAAFGANLLGLFEIQLPWWIAGRLGGATGRNTMAG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCCCCCCC
HAVNGFVMTLLATPCSAPFVGTAVAFALSQAAPQILLVFTALGLGMAAPYLGLAAAPRLA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ALFPRPGRWMLTLRAVAALAMIATASWLLRVLADISGVAAAAMLAAVLLVPALILTMLRF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRRTVAGAGVIVAIGLVLTAATAIRHSDGPGRSDGIAWRPLVPTDIATQVSAGHTVFVD
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHCCCCEEEEE
IGASWCVTCKVNEKLVIDSTAVRSRLTSVVTVRADWTSHDDTIAAYLQSFGRYGLPFNVV
CCCCEEEEEEECCEEEECHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
FGPGAPAGIVLPELLTPQIVLDAIDTASTIPPKETDKT
ECCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIRHPRWLGLLLGALLVATTAASAASRPQPNLATRLLVGHVARTDSGVTTAWAGLDVRL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEE
GAGWHTYWRSAGDAGAPPEFDWAGSANVADVTVEWPAPRRFSEQDIDTFGYDEHVLFPLR
CCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEE
VRLQDGAAPAYLKLKAVLFVCSIICTQQETQLEADIPAASHQPNDQALIEEWRQSVPRET
EEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
APGLSVTALRIERQPKPQLRLEALATPPLRAPDVFVDGSEAVSGGRAQVSNSSDGAVTIH
CCCCEEEEEEECCCCCCCEEHHEECCCCCCCCCEEECCHHHCCCCCEEECCCCCCEEEEE
VPLQGLDQAAAGERLRVTLVDGDRAIEATLPVDAHTVAATSATIRPHAAAASIWTILGVA
EECCCCCHHCCCCEEEEEEECCCCEEEEECCCCCHHEEECCCCCCCCHHHHHHHHHHHHH
LLGGFILNFMPCVFPVLSLKLVSLVDHDPARAPSRRPAFLATAAGIIASFVTLALVLSSL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KAAGAEVGWGLQFQQPAFLIAMIVVLAAFGANLLGLFEIQLPWWIAGRLGGATGRNTMAG
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCCCCCCC
HAVNGFVMTLLATPCSAPFVGTAVAFALSQAAPQILLVFTALGLGMAAPYLGLAAAPRLA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ALFPRPGRWMLTLRAVAALAMIATASWLLRVLADISGVAAAAMLAAVLLVPALILTMLRF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLRRTVAGAGVIVAIGLVLTAATAIRHSDGPGRSDGIAWRPLVPTDIATQVSAGHTVFVD
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHCCCCEEEEE
IGASWCVTCKVNEKLVIDSTAVRSRLTSVVTVRADWTSHDDTIAAYLQSFGRYGLPFNVV
CCCCEEEEEEECCEEEECHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
FGPGAPAGIVLPELLTPQIVLDAIDTASTIPPKETDKT
ECCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA