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The map label for this gene is iorA [H]

Identifier: 146340146

GI number: 146340146

Start: 3363474

End: 3363962

Strand: Reverse

Name: iorA [H]

Synonym: BRADO3161

Alternate gene names: 146340146

Gene position: 3363962-3363474 (Counterclockwise)

Preceding gene: 146340147

Following gene: 146340145

Centisome position: 45.11

GC content: 67.08

Gene sequence:

>489_bases
ATGACCCTCACGATCAACGGCCGCGATCACCAGGTGGACGCGGAGCCGGACACGCCGCTGCTCTACGTGCTGCGCGACGA
TCTCGCACTCAACGCGGCGAAATATGGCTGCGGGCTAGGCCAATGCGGCGCTTGCACGGTCATGATCGACGGCGAGGCCG
TATTCTCCTGCATCACGCCCGTCCTGCTTCTCGCAGGCCGCAAGATCACCACGCTCGAAGGATTGGGCACGGAGGAAGCG
CCGGCCCCGATCCAGCGCGCCTTCATCGAAGAGCAGGCCGCGCAATGCGGCTACTGTATCCCGGGCATGATGATGCGCGC
GCATGCACTGCTGCAGCGCAATGCCAGCCCGACCGACCTGCAGATCCGCGCCGAGCTGGCGCCGCATCTCTGTCGTTGCG
GCACGCACATGCGCATCCTGCGCGCGGTGCATCGGGCCGCGGACATGGTGCGCCGGGCCGATGCCGGCACCGAGGGAGGC
AGGTTATGA

Upstream 100 bases:

>100_bases
AGACCCTCGCCGGGGCACGCCGGGCACAGGCGAGCTTCCTCCGCACGGCGGCCGAGCCGCCCAACATCAGCATCACCGGG
ACGACGCGAGGCCAGCCATG

Downstream 100 bases:

>100_bases
CGTCAACTATCACCCTCGATCGTCGTGGCGTCCTGCTCGGCGGCGGCGCCCTGATCGTCAGTTTCGCCCTGCGCGACACC
GCCGCGCAGCCGTTACCGGG

Product: putative oxidoreductase subunit protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTLTINGRDHQVDAEPDTPLLYVLRDDLALNAAKYGCGLGQCGACTVMIDGEAVFSCITPVLLLAGRKITTLEGLGTEEA
PAPIQRAFIEEQAAQCGYCIPGMMMRAHALLQRNASPTDLQIRAELAPHLCRCGTHMRILRAVHRAADMVRRADAGTEGG
RL

Sequences:

>Translated_162_residues
MTLTINGRDHQVDAEPDTPLLYVLRDDLALNAAKYGCGLGQCGACTVMIDGEAVFSCITPVLLLAGRKITTLEGLGTEEA
PAPIQRAFIEEQAAQCGYCIPGMMMRAHALLQRNASPTDLQIRAELAPHLCRCGTHMRILRAVHRAADMVRRADAGTEGG
RL
>Mature_161_residues
TLTINGRDHQVDAEPDTPLLYVLRDDLALNAAKYGCGLGQCGACTVMIDGEAVFSCITPVLLLAGRKITTLEGLGTEEAP
APIQRAFIEEQAAQCGYCIPGMMMRAHALLQRNASPTDLQIRAELAPHLCRCGTHMRILRAVHRAADMVRRADAGTEGGR
L

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=34.4155844155844, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI71773480, Length=150, Percent_Identity=38, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=35.5421686746988, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=40.8450704225352, Blast_Score=102, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=37.3417721518987, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=35.9477124183007, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=34.640522875817, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=34.8684210526316, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=32.4675324675325, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=31.6129032258064, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=32.7160493827161, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=32.7160493827161, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17457; Mature: 17325

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTINGRDHQVDAEPDTPLLYVLRDDLALNAAKYGCGLGQCGACTVMIDGEAVFSCITP
CEEEECCCCCEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
VLLLAGRKITTLEGLGTEEAPAPIQRAFIEEQAAQCGYCIPGMMMRAHALLQRNASPTDL
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCE
QIRAELAPHLCRCGTHMRILRAVHRAADMVRRADAGTEGGRL
EEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TLTINGRDHQVDAEPDTPLLYVLRDDLALNAAKYGCGLGQCGACTVMIDGEAVFSCITP
EEEECCCCCEECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
VLLLAGRKITTLEGLGTEEAPAPIQRAFIEEQAAQCGYCIPGMMMRAHALLQRNASPTDL
HHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCE
QIRAELAPHLCRCGTHMRILRAVHRAADMVRRADAGTEGGRL
EEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]