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The map label for this gene is hfaC [H]

Identifier: 146340131

GI number: 146340131

Start: 3345703

End: 3347511

Strand: Reverse

Name: hfaC [H]

Synonym: BRADO3146

Alternate gene names: 146340131

Gene position: 3347511-3345703 (Counterclockwise)

Preceding gene: 146340132

Following gene: 146340130

Centisome position: 44.89

GC content: 66.89

Gene sequence:

>1809_bases
ATGGCGCCGCCTCTCATCCAACTCAAGGACATCCGCCTGACCTTCGGCGGCACGGCGCTGCTGCAAGGCGTGGAGCTGTC
GGTGTCGCCCGGCGAGCGCGTCTGCCTGATCGGCCGCAACGGCTCAGGCAAGTCGACCTTGTTGAAGATCGCAGCCGGGC
TGGTCGACTGCGACAGCGGCACGCGCTTCGTGCAGCCCGGCGCGACCGTACGCTATCTGCCGCAGGAGCCGGATTTCTCC
GGCCATGCCACGACGCTCTCCTACGTTGAGGCCGGGCTCGGGCCCGGCGACGATCACTACCAGGCACGTTATCTCGTCGA
ACAGCTTGGTCTCACCGGTGAGGAAGATCCCGCGCACGTCTCCGGCGGCGAGGCGCGCCGCGCGGCGCTGGCGCGCGTGC
TCGCGCCCAATCCCGACATTCTGCTCCTGGACGAGCCGACCAACCATCTCGACCTCACCACCATCGAGTGGCTGGAGAAC
GAGCTCGATGGCCGCCGCTGCGCGCTGGTGCTGATCAGCCACGATCGCCGCTTCCTCACCAACCTGTCGCGCGCGACCGC
CTGGCTCGATCGCGGTCAGATCAAGCAGATCGACCGCGGTTTTGCGGCGTTCGAGGCGTGGCGTGACGAAGTCCTGGCGG
AAGAAGAGCGCGAGCAGCACAAGCTCGACCGCAAGATCGTCAACGAGGAGCACTGGCTGCGCTACGGCGTCTCCGGCCGG
CGCAAGCGCAACGTCAAGCGGCTCGCCAATCTGCATGCGCTGCGCCAGCAGCGCCGCGACTATCGCGGCACCGCAGGCAG
CGCCAATCTCGCCGCGGCCGAGGCCGACAAGTCCGGCAAGCTGGTGATCGAGGCCAAGGGGGCGTCGAAGAGTTTCGGCA
ATCGCAAGATCATCGACAATTTCTCCATCCGTATCCAGCGCGGCGACCGCATCGGCATCGTCGGCCCGAACGGCGCTGGC
AAGACCACGCTGGTCAACCTGCTCACCGGCGGCAGCGAGCCGGACAGCGGCAGCGTCCGGCTCGGCGTCAATCTGGAGAT
GGCGACGCTGGACCAGCATCGCGAGAGCCTCGATCCGCGCACGACGTTGGCAGAGGCGCTGACCGGCGGCCGCGGCGATC
ACGTCATGGTGGCGGGCAAGCCGAAGCACGTTGTCGGCTACATGGAGGACTTCCTGTTCTCGCGCGAGCAGATGCGGACC
CCGCTCGAGGTGCTGTCCGGCGGCGAGCGCGGCCGGCTGATGCTGGCGCGCGCGCTCGCAAAACCCTCGAACCTGCTGGT
GCTGGACGAGCCGACCAACGATCTCGATCTCGAGACGCTGGACGTATTGGAGGACATGCTCGGCGACTACGAGGGCACGG
TCATCCTGATCAGCCACGATCGCGACTTCCTCGACCGCGTCGTCACCTCGGTAATCGTGCCCGAGGGCAACGGCAAGTGG
CAGGAATATGCCGGCGGCTACAGCGACATGCTGGTCCAGCGCGGCGCCGATTTGAAGCGCGAGCACGCGAAGGCGGCTGA
GGAAAAGAAAGAGACGAAGCCGGCCACCGCCGCGCCCGCAAGCGCGCCGAAGCGCAAGCTCTCTTTCAACGAGAAGCACG
CGCTGGAGACGCTGCCGAAGACGATCGCGAAGCTGCAAGCCGAGATCGCCAAGCAGCAGGCCGTGCTCGCCGACCCCGCG
CTTTATTCGAAAGATCGCAAGAAATTCGACGCCGCCTCCCTCGCCATCGCGGCAGCGCAAGCCGAGCTCACCGCCGCGGA
GGACCGCTGGCTGGAGCTCGAAGTCCTGCGCGAGGAGATCGAGGGATAA

Upstream 100 bases:

>100_bases
CCACGCGACCGCTCCACATTCCTGTCCACCCTCGACACCACGATCCGCCGCGTGCAGCGCCAGCGCGCCGCGCGGATCCA
GCAACAGAGCTAGCATCACG

Downstream 100 bases:

>100_bases
CGCTGCGTAGGGTGGGCAAAGGCGCGCAAGCGCCGTGCCCACCGCGTTCTTGCACAACAACAAATGGTGGGCACGCTTCG
CTTTGCCCACCCTACGTTCT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MAPPLIQLKDIRLTFGGTALLQGVELSVSPGERVCLIGRNGSGKSTLLKIAAGLVDCDSGTRFVQPGATVRYLPQEPDFS
GHATTLSYVEAGLGPGDDHYQARYLVEQLGLTGEEDPAHVSGGEARRAALARVLAPNPDILLLDEPTNHLDLTTIEWLEN
ELDGRRCALVLISHDRRFLTNLSRATAWLDRGQIKQIDRGFAAFEAWRDEVLAEEEREQHKLDRKIVNEEHWLRYGVSGR
RKRNVKRLANLHALRQQRRDYRGTAGSANLAAAEADKSGKLVIEAKGASKSFGNRKIIDNFSIRIQRGDRIGIVGPNGAG
KTTLVNLLTGGSEPDSGSVRLGVNLEMATLDQHRESLDPRTTLAEALTGGRGDHVMVAGKPKHVVGYMEDFLFSREQMRT
PLEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGKW
QEYAGGYSDMLVQRGADLKREHAKAAEEKKETKPATAAPASAPKRKLSFNEKHALETLPKTIAKLQAEIAKQQAVLADPA
LYSKDRKKFDAASLAIAAAQAELTAAEDRWLELEVLREEIEG

Sequences:

>Translated_602_residues
MAPPLIQLKDIRLTFGGTALLQGVELSVSPGERVCLIGRNGSGKSTLLKIAAGLVDCDSGTRFVQPGATVRYLPQEPDFS
GHATTLSYVEAGLGPGDDHYQARYLVEQLGLTGEEDPAHVSGGEARRAALARVLAPNPDILLLDEPTNHLDLTTIEWLEN
ELDGRRCALVLISHDRRFLTNLSRATAWLDRGQIKQIDRGFAAFEAWRDEVLAEEEREQHKLDRKIVNEEHWLRYGVSGR
RKRNVKRLANLHALRQQRRDYRGTAGSANLAAAEADKSGKLVIEAKGASKSFGNRKIIDNFSIRIQRGDRIGIVGPNGAG
KTTLVNLLTGGSEPDSGSVRLGVNLEMATLDQHRESLDPRTTLAEALTGGRGDHVMVAGKPKHVVGYMEDFLFSREQMRT
PLEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGKW
QEYAGGYSDMLVQRGADLKREHAKAAEEKKETKPATAAPASAPKRKLSFNEKHALETLPKTIAKLQAEIAKQQAVLADPA
LYSKDRKKFDAASLAIAAAQAELTAAEDRWLELEVLREEIEG
>Mature_601_residues
APPLIQLKDIRLTFGGTALLQGVELSVSPGERVCLIGRNGSGKSTLLKIAAGLVDCDSGTRFVQPGATVRYLPQEPDFSG
HATTLSYVEAGLGPGDDHYQARYLVEQLGLTGEEDPAHVSGGEARRAALARVLAPNPDILLLDEPTNHLDLTTIEWLENE
LDGRRCALVLISHDRRFLTNLSRATAWLDRGQIKQIDRGFAAFEAWRDEVLAEEEREQHKLDRKIVNEEHWLRYGVSGRR
KRNVKRLANLHALRQQRRDYRGTAGSANLAAAEADKSGKLVIEAKGASKSFGNRKIIDNFSIRIQRGDRIGIVGPNGAGK
TTLVNLLTGGSEPDSGSVRLGVNLEMATLDQHRESLDPRTTLAEALTGGRGDHVMVAGKPKHVVGYMEDFLFSREQMRTP
LEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGKWQ
EYAGGYSDMLVQRGADLKREHAKAAEEKKETKPATAAPASAPKRKLSFNEKHALETLPKTIAKLQAEIAKQQAVLADPAL
YSKDRKKFDAASLAIAAAQAELTAAEDRWLELEVLREEIEG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=546, Percent_Identity=28.021978021978, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI10947137, Length=531, Percent_Identity=27.4952919020716, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI27881506, Length=531, Percent_Identity=27.4952919020716, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI69354671, Length=390, Percent_Identity=28.7179487179487, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI10947135, Length=390, Percent_Identity=28.7179487179487, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI9961252, Length=249, Percent_Identity=28.5140562248996, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI4505771, Length=249, Percent_Identity=28.5140562248996, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI9961250, Length=249, Percent_Identity=28.5140562248996, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1787182, Length=632, Percent_Identity=38.2911392405063, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI2367384, Length=513, Percent_Identity=35.4775828460039, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1787041, Length=536, Percent_Identity=28.1716417910448, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1789751, Length=645, Percent_Identity=27.7519379844961, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1788225, Length=223, Percent_Identity=31.390134529148, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788761, Length=228, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994943, Length=588, Percent_Identity=24.8299319727891, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=29.3023255813954, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787712, Length=213, Percent_Identity=27.6995305164319, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788506, Length=519, Percent_Identity=24.4701348747592, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788165, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=28.1553398058252, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081782, Length=492, Percent_Identity=24.1869918699187, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786253, Length=200, Percent_Identity=32.5, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787105, Length=201, Percent_Identity=31.8407960199005, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787758, Length=188, Percent_Identity=32.4468085106383, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789672, Length=212, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790739, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48995001, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786319, Length=210, Percent_Identity=27.1428571428571, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693107, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790190, Length=207, Percent_Identity=28.0193236714976, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1789593, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786975, Length=211, Percent_Identity=25.5924170616114, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787164, Length=205, Percent_Identity=31.7073170731707, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787792, Length=196, Percent_Identity=31.1224489795918, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787112, Length=238, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786872, Length=216, Percent_Identity=28.2407407407407, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=554, Percent_Identity=27.0758122743682, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553372, Length=524, Percent_Identity=27.0992366412214, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17555318, Length=373, Percent_Identity=30.5630026809651, Blast_Score=139, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6320874, Length=522, Percent_Identity=26.8199233716475, Blast_Score=153, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6321121, Length=566, Percent_Identity=26.1484098939929, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323278, Length=350, Percent_Identity=30.2857142857143, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=349, Percent_Identity=28.3667621776504, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=274, Percent_Identity=28.4671532846715, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24642252, Length=554, Percent_Identity=28.3393501805054, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI18859989, Length=554, Percent_Identity=28.3393501805054, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=26.8292682926829, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24666836, Length=528, Percent_Identity=28.4090909090909, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI281363262, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653245, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666092, Length=223, Percent_Identity=30.0448430493274, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 66061; Mature: 65929

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00449 ATPASE_A ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPLIQLKDIRLTFGGTALLQGVELSVSPGERVCLIGRNGSGKSTLLKIAAGLVDCDSG
CCCCCEEEEEEEEEECCHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHEECCCC
TRFVQPGATVRYLPQEPDFSGHATTLSYVEAGLGPGDDHYQARYLVEQLGLTGEEDPAHV
CEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGEARRAALARVLAPNPDILLLDEPTNHLDLTTIEWLENELDGRRCALVLISHDRRFLT
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHH
NLSRATAWLDRGQIKQIDRGFAAFEAWRDEVLAEEEREQHKLDRKIVNEEHWLRYGVSGR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCH
RKRNVKRLANLHALRQQRRDYRGTAGSANLAAAEADKSGKLVIEAKGASKSFGNRKIIDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEEEEC
FSIRIQRGDRIGIVGPNGAGKTTLVNLLTGGSEPDSGSVRLGVNLEMATLDQHRESLDPR
EEEEEEECCEEEEECCCCCCCHHEEEEECCCCCCCCCCEEEEEEEEEHHHHHHHHHCCHH
TTLAEALTGGRGDHVMVAGKPKHVVGYMEDFLFSREQMRTPLEVLSGGERGRLMLARALA
HHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCHHHHHHHHC
KPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGKW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEEEECCCCCH
QEYAGGYSDMLVQRGADLKREHAKAAEEKKETKPATAAPASAPKRKLSFNEKHALETLPK
HHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHH
TIAKLQAEIAKQQAVLADPALYSKDRKKFDAASLAIAAAQAELTAAEDRWLELEVLREEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EG
CC
>Mature Secondary Structure 
APPLIQLKDIRLTFGGTALLQGVELSVSPGERVCLIGRNGSGKSTLLKIAAGLVDCDSG
CCCCEEEEEEEEEECCHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHEECCCC
TRFVQPGATVRYLPQEPDFSGHATTLSYVEAGLGPGDDHYQARYLVEQLGLTGEEDPAHV
CEEECCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGEARRAALARVLAPNPDILLLDEPTNHLDLTTIEWLENELDGRRCALVLISHDRRFLT
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEECCHHHHH
NLSRATAWLDRGQIKQIDRGFAAFEAWRDEVLAEEEREQHKLDRKIVNEEHWLRYGVSGR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCH
RKRNVKRLANLHALRQQRRDYRGTAGSANLAAAEADKSGKLVIEAKGASKSFGNRKIIDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCEEEEC
FSIRIQRGDRIGIVGPNGAGKTTLVNLLTGGSEPDSGSVRLGVNLEMATLDQHRESLDPR
EEEEEEECCEEEEECCCCCCCHHEEEEECCCCCCCCCCEEEEEEEEEHHHHHHHHHCCHH
TTLAEALTGGRGDHVMVAGKPKHVVGYMEDFLFSREQMRTPLEVLSGGERGRLMLARALA
HHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCHHHHHHHHC
KPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGKW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEEEECCCCCH
QEYAGGYSDMLVQRGADLKREHAKAAEEKKETKPATAAPASAPKRKLSFNEKHALETLPK
HHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHHHH
TIAKLQAEIAKQQAVLADPALYSKDRKKFDAASLAIAAAQAELTAAEDRWLELEVLREEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]