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The map label for this gene is yngJ [H]

Identifier: 146340123

GI number: 146340123

Start: 3336402

End: 3337547

Strand: Direct

Name: yngJ [H]

Synonym: BRADO3138

Alternate gene names: 146340123

Gene position: 3336402-3337547 (Clockwise)

Preceding gene: 146340122

Following gene: 146340124

Centisome position: 44.74

GC content: 66.58

Gene sequence:

>1146_bases
ATGCAGTTCGCTCTCGATGAGGATCAGATCGCGGTGCGCGACATGGCGCGCGCCTTTGCGGCCGAGAAGATCGCCCCGCA
TGCGCTGCGCTGGGACGAGGACAAGCATTTCCCCGTCGACGTCATGCGCGAGGCCGCCGCGCTCGGCATGGGCGGCATCT
ACATCCGCGACGATGTCGGCGGCTCGGGCCTGACCCGGCTCGATGCGGCGTTGATCTTCGAGGCGCTGGCGACGGGCTGC
CCCACGGTGTCGGCCTTCATCTCCATCCACAACATGGCATCGTGGATGATCGACACGTTCGGCACCGAGGCGCAGCGGCA
AGAGTATTTGCCGAAGCTCTGCCCGATGGACCTGATTGCGAGCTACTGCCTGACCGAGCCGGGCGCCGGCTCCGACGCCG
CGGCGCTGCGCACTCGCGCAGTGCGCGATGGCGACGACTACGTGATCAACGGCCAGAAGCAGTTCATCTCCGGCGCCGGC
GCCACCGATATCCTGGTTGCGATGGTGCGCACGGGCGCCGATGGTCCCGGCGGCATCTCGACTCTCGTCATCGACGCCAA
GACGCCGGGCGTGTCGTTCGGCGCCAATGAGCGCAAGATGGGCTGGAATGCACAGCCGACACGCGCCGTGATTTTCGAGA
ACGCGCGCGTTCCGGTCGCGAACCGGCTCGGCGAGGAGGGCATCGGCTTCAAGATCGCGATGGCCGGGCTCGATGGCGGC
CGTCTCAACATCGCGGCCTGCTCGCTGGGCGGCGCGCAGGCCGCACTCGACAAGACCTTGGCCTATACCAGGGAGCGCAA
GGCGTTCGGCAAGCGGCTCGACGAATTCCAGGCGCTGCAGTTCCGGATCGCCGACATGGCGATCGAACTGGAGGCGGCGC
GCACCTTCCTGTGGCGCGCGGCGGCGGCGCTCGATCACAAGGATGCCGATGCGACGATGCTGTGCGCGATGGCCAAGCGC
TTCGGCACCGATGTCGGCTTCGAGGTCGCCAATCAGGCGCTGCAGCTGCATGGCGGCTATGGCTACCTGAGCGAATACGG
CATCGAGAAGATCGTTCGCGATTTGCGGGTGCACCAGATCCTCGAGGGCACCAACGAGATCATGCGCCTGATCGTGTCGC
GCAAGCTGATCGAGGCCGCGCGATGA

Upstream 100 bases:

>100_bases
GGGTGACTCTGGATTGCTTCGTCGCTTCGCTCCTCGCAATGACGGAATGTGAGGACGCGCCGAACGCAACCAACTAAAAA
CACGGAAACGCGGAGAACGA

Downstream 100 bases:

>100_bases
GCGACGCGGTCGAAGGCGATTTGATCGTTCGCCGCGAGGGATCTGCGGGCATCATCCGGCTCAACCGGCCCAAGGCGATC
AATGCGATGACGCTGGAGAT

Product: acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MQFALDEDQIAVRDMARAFAAEKIAPHALRWDEDKHFPVDVMREAAALGMGGIYIRDDVGGSGLTRLDAALIFEALATGC
PTVSAFISIHNMASWMIDTFGTEAQRQEYLPKLCPMDLIASYCLTEPGAGSDAAALRTRAVRDGDDYVINGQKQFISGAG
ATDILVAMVRTGADGPGGISTLVIDAKTPGVSFGANERKMGWNAQPTRAVIFENARVPVANRLGEEGIGFKIAMAGLDGG
RLNIAACSLGGAQAALDKTLAYTRERKAFGKRLDEFQALQFRIADMAIELEAARTFLWRAAAALDHKDADATMLCAMAKR
FGTDVGFEVANQALQLHGGYGYLSEYGIEKIVRDLRVHQILEGTNEIMRLIVSRKLIEAAR

Sequences:

>Translated_381_residues
MQFALDEDQIAVRDMARAFAAEKIAPHALRWDEDKHFPVDVMREAAALGMGGIYIRDDVGGSGLTRLDAALIFEALATGC
PTVSAFISIHNMASWMIDTFGTEAQRQEYLPKLCPMDLIASYCLTEPGAGSDAAALRTRAVRDGDDYVINGQKQFISGAG
ATDILVAMVRTGADGPGGISTLVIDAKTPGVSFGANERKMGWNAQPTRAVIFENARVPVANRLGEEGIGFKIAMAGLDGG
RLNIAACSLGGAQAALDKTLAYTRERKAFGKRLDEFQALQFRIADMAIELEAARTFLWRAAAALDHKDADATMLCAMAKR
FGTDVGFEVANQALQLHGGYGYLSEYGIEKIVRDLRVHQILEGTNEIMRLIVSRKLIEAAR
>Mature_381_residues
MQFALDEDQIAVRDMARAFAAEKIAPHALRWDEDKHFPVDVMREAAALGMGGIYIRDDVGGSGLTRLDAALIFEALATGC
PTVSAFISIHNMASWMIDTFGTEAQRQEYLPKLCPMDLIASYCLTEPGAGSDAAALRTRAVRDGDDYVINGQKQFISGAG
ATDILVAMVRTGADGPGGISTLVIDAKTPGVSFGANERKMGWNAQPTRAVIFENARVPVANRLGEEGIGFKIAMAGLDGG
RLNIAACSLGGAQAALDKTLAYTRERKAFGKRLDEFQALQFRIADMAIELEAARTFLWRAAAALDHKDADATMLCAMAKR
FGTDVGFEVANQALQLHGGYGYLSEYGIEKIVRDLRVHQILEGTNEIMRLIVSRKLIEAAR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=58.2887700534759, Blast_Score=467, Evalue=1e-131,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=38.9473684210526, Blast_Score=274, Evalue=8e-74,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=38.9473684210526, Blast_Score=274, Evalue=9e-74,
Organism=Homo sapiens, GI4557233, Length=379, Percent_Identity=36.9393139841689, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=35.7333333333333, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI4501857, Length=369, Percent_Identity=32.7913279132791, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI76496475, Length=335, Percent_Identity=34.6268656716418, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI4557235, Length=335, Percent_Identity=34.6268656716418, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=31.9148936170213, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=33.8983050847458, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=32.4404761904762, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=26.8421052631579, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI7669494, Length=352, Percent_Identity=26.7045454545455, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38505218, Length=350, Percent_Identity=27.7142857142857, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI48976061, Length=350, Percent_Identity=28.2857142857143, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI211971008, Length=350, Percent_Identity=28.2857142857143, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=29.242819843342, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786223, Length=388, Percent_Identity=28.0927835051546, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082384, Length=268, Percent_Identity=26.865671641791, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=49.0666666666667, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=39.2670157068063, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=38.5826771653543, Blast_Score=284, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=33.3333333333333, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=36.7123287671233, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=35.6382978723404, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=33.4277620396601, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=31.8421052631579, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71990804, Length=260, Percent_Identity=38.4615384615385, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=32.3529411764706, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=32.3529411764706, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=39.1304347826087, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=32.6666666666667, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=31.021897810219, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=25.6, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=28.955223880597, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=235, Percent_Identity=28.0851063829787, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=322, Percent_Identity=23.6024844720497, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=322, Percent_Identity=23.6024844720497, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=38.3812010443864, Blast_Score=271, Evalue=4e-73,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=34.7480106100796, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=36.7021276595745, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=36.1702127659575, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=33.9473684210526, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=33.2369942196532, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=27.5590551181102, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 41179; Mature: 41179

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFALDEDQIAVRDMARAFAAEKIAPHALRWDEDKHFPVDVMREAAALGMGGIYIRDDVG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCC
GSGLTRLDAALIFEALATGCPTVSAFISIHNMASWMIDTFGTEAQRQEYLPKLCPMDLIA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHCCCHHHHH
SYCLTEPGAGSDAAALRTRAVRDGDDYVINGQKQFISGAGATDILVAMVRTGADGPGGIS
HHHHCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHCCCCCCCCE
TLVIDAKTPGVSFGANERKMGWNAQPTRAVIFENARVPVANRLGEEGIGFKIAMAGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEEECCCCC
RLNIAACSLGGAQAALDKTLAYTRERKAFGKRLDEFQALQFRIADMAIELEAARTFLWRA
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALDHKDADATMLCAMAKRFGTDVGFEVANQALQLHGGYGYLSEYGIEKIVRDLRVHQI
HHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRLIVSRKLIEAAR
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFALDEDQIAVRDMARAFAAEKIAPHALRWDEDKHFPVDVMREAAALGMGGIYIRDDVG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCC
GSGLTRLDAALIFEALATGCPTVSAFISIHNMASWMIDTFGTEAQRQEYLPKLCPMDLIA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHCCCHHHHH
SYCLTEPGAGSDAAALRTRAVRDGDDYVINGQKQFISGAGATDILVAMVRTGADGPGGIS
HHHHCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHCCCCCCCCE
TLVIDAKTPGVSFGANERKMGWNAQPTRAVIFENARVPVANRLGEEGIGFKIAMAGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEEEECCCCC
RLNIAACSLGGAQAALDKTLAYTRERKAFGKRLDEFQALQFRIADMAIELEAARTFLWRA
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALDHKDADATMLCAMAKRFGTDVGFEVANQALQLHGGYGYLSEYGIEKIVRDLRVHQI
HHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRLIVSRKLIEAAR
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]