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The map label for this gene is steT [H]

Identifier: 146339972

GI number: 146339972

Start: 3180271

End: 3181644

Strand: Direct

Name: steT [H]

Synonym: BRADO2977

Alternate gene names: 146339972

Gene position: 3180271-3181644 (Clockwise)

Preceding gene: 146339970

Following gene: 146339973

Centisome position: 42.65

GC content: 65.5

Gene sequence:

>1374_bases
ATGGCTGCAGCTGAGGCGCACGACAGCAAGCGGGCAAGCCGGTCGGGCAACACCGCACTCCCATCCGTGTCGCTGCCGGT
CGCCATTGCCATCGTGATCGCCGACATGATCGGGGTCGGCGTCTTCACCAGCCTGGGCTTCCAGGTCAAGGATCTTCCTT
CGGGTTTCGCCATCCTGCTGTTGTGGGCCGTCGGCGGTCTCGTTTCGATCTGCGGGGCGCTCTCCTATGCCGAGCTCGGC
ACAATGTTTCCGCGCTCGAGCGGCGAATACAATTTTCTGACCCGGGCGTTTCATCCTGCGGTCGGCTTCATGGCCGGCTG
GGTGTCGTCCACGGTCGGCTTCGCCGCTCCGGTGGCGCTGGCGGCGATGGCATTTGGCGAATATGGCCGCGCCGTGCTGC
CGAGCGTGCCGCCGATGGTGCTGGCTGTCGGCGCCGTTTGGCTGGTGACGGTTGTGCAACTCGGCGGCATCCAGCAATCC
AGCCGTTTCCAGCTGTTGTCGACAATGTTGAAGCTCGGCCTGATCCTCGCCTTCCTGATCGCGGGCGCGATCATTTCGGA
TCCGCAACCGGTCAGGTTCGCGCCTGCCGCTGCCGATGTCGGCTATATCACCAGCGCGGCCTTCGCGACCGGCCTGGTGT
TCGTGATGTACGCGTTCTCCGGCTGGAATGCGGCGACCTACATCATCGGCGAGTTGCATGCGCCCGATCACAGCCTGCCG
CGCGCGCTGCTCGTGGGCACCCTGATCGTGATCGTGCTCTACGTGTCGCTGAACGCCGTGTTCCTCCGGGCGGCGCCGAC
GAGCGAGCTTGCAGGGCAGCTGCAGGTGGCCAGCATCGCTGGCGCGCACATCTTCGGCGAGACGGGAGGCCGCTTCGTCG
CGGCGATGATCTGCGTCGGATTGGTGCCGTCGATCGCTGCGATGATGTGGATCGGCCCGCGCGTGCTGATGACGATGGGC
GAGGATATCCCGGCGCTCGCGCTGTTCGCCCGCCGGTCGCGCCAGGGCGCGCCGGTCTACGCGGTCCTGTTCCAGCTCGC
AGTGGCAACCCTGATGCTGTTCACGGAGAGCTTCGAGGCGGTGCTGGACGTCGTCCAGTTCTCGCTGTTGTCCTGCTCGT
TCCTGACGGTGCTGGGGTTGCTCTGGCTGCGCATCACCGCGCCCGATCTGTCGCGGCCGTATCGCGCATGGGGGTATCCC
GTGACGCCCTTGATCTTCCTCAGCGTGACCGGTTTCATGATGTACTACCTCGTTACAGCACGGCCGTGGCAGGCCGGGTT
CGGTGCTGCGGCGATGTTGTCGGGACTGCTGATCTATTGGTTCGCTCAAGCGCGGTCGCGCACCGCCGCAGCAGCGATGT
CAGGTCCGGATTGA

Upstream 100 bases:

>100_bases
ACATCGCCATACTTATCGCGCGTTAACTATGATTGAATGGCGTTGCCGGAGCATGGGCCTGAAGCTTGAGGGAAGGGGCG
TCACTTGCCCGTCGAACGAC

Downstream 100 bases:

>100_bases
AAGATGCTGCTGCTGTCGAGACTGTGCTTTGCTGCTGCGTGCTTCATCGTTGCGATGAGTGGCGACCTCCAGGCTCAGAC
CATCACGCCCGATGATACCG

Product: putative amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAAAEAHDSKRASRSGNTALPSVSLPVAIAIVIADMIGVGVFTSLGFQVKDLPSGFAILLLWAVGGLVSICGALSYAELG
TMFPRSSGEYNFLTRAFHPAVGFMAGWVSSTVGFAAPVALAAMAFGEYGRAVLPSVPPMVLAVGAVWLVTVVQLGGIQQS
SRFQLLSTMLKLGLILAFLIAGAIISDPQPVRFAPAAADVGYITSAAFATGLVFVMYAFSGWNAATYIIGELHAPDHSLP
RALLVGTLIVIVLYVSLNAVFLRAAPTSELAGQLQVASIAGAHIFGETGGRFVAAMICVGLVPSIAAMMWIGPRVLMTMG
EDIPALALFARRSRQGAPVYAVLFQLAVATLMLFTESFEAVLDVVQFSLLSCSFLTVLGLLWLRITAPDLSRPYRAWGYP
VTPLIFLSVTGFMMYYLVTARPWQAGFGAAAMLSGLLIYWFAQARSRTAAAAMSGPD

Sequences:

>Translated_457_residues
MAAAEAHDSKRASRSGNTALPSVSLPVAIAIVIADMIGVGVFTSLGFQVKDLPSGFAILLLWAVGGLVSICGALSYAELG
TMFPRSSGEYNFLTRAFHPAVGFMAGWVSSTVGFAAPVALAAMAFGEYGRAVLPSVPPMVLAVGAVWLVTVVQLGGIQQS
SRFQLLSTMLKLGLILAFLIAGAIISDPQPVRFAPAAADVGYITSAAFATGLVFVMYAFSGWNAATYIIGELHAPDHSLP
RALLVGTLIVIVLYVSLNAVFLRAAPTSELAGQLQVASIAGAHIFGETGGRFVAAMICVGLVPSIAAMMWIGPRVLMTMG
EDIPALALFARRSRQGAPVYAVLFQLAVATLMLFTESFEAVLDVVQFSLLSCSFLTVLGLLWLRITAPDLSRPYRAWGYP
VTPLIFLSVTGFMMYYLVTARPWQAGFGAAAMLSGLLIYWFAQARSRTAAAAMSGPD
>Mature_456_residues
AAAEAHDSKRASRSGNTALPSVSLPVAIAIVIADMIGVGVFTSLGFQVKDLPSGFAILLLWAVGGLVSICGALSYAELGT
MFPRSSGEYNFLTRAFHPAVGFMAGWVSSTVGFAAPVALAAMAFGEYGRAVLPSVPPMVLAVGAVWLVTVVQLGGIQQSS
RFQLLSTMLKLGLILAFLIAGAIISDPQPVRFAPAAADVGYITSAAFATGLVFVMYAFSGWNAATYIIGELHAPDHSLPR
ALLVGTLIVIVLYVSLNAVFLRAAPTSELAGQLQVASIAGAHIFGETGGRFVAAMICVGLVPSIAAMMWIGPRVLMTMGE
DIPALALFARRSRQGAPVYAVLFQLAVATLMLFTESFEAVLDVVQFSLLSCSFLTVLGLLWLRITAPDLSRPYRAWGYPV
TPLIFLSVTGFMMYYLVTARPWQAGFGAAAMLSGLLIYWFAQARSRTAAAAMSGPD

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=467, Percent_Identity=25.9100642398287, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7657591, Length=467, Percent_Identity=25.9100642398287, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI33286428, Length=462, Percent_Identity=27.4891774891775, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI7657683, Length=407, Percent_Identity=26.044226044226, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI115648063, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI115648022, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI71979932, Length=458, Percent_Identity=24.0174672489083, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI186910308, Length=439, Percent_Identity=25.9681093394077, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI186910306, Length=439, Percent_Identity=25.9681093394077, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI186910304, Length=439, Percent_Identity=25.9681093394077, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI9790235, Length=416, Percent_Identity=25.9615384615385, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71999149, Length=387, Percent_Identity=24.031007751938, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI33286430, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082250, Length=365, Percent_Identity=25.4794520547945, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17540018, Length=461, Percent_Identity=25.8134490238612, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566699, Length=399, Percent_Identity=25.31328320802, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71995388, Length=448, Percent_Identity=27.0089285714286, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71995382, Length=448, Percent_Identity=27.0089285714286, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982608, Length=379, Percent_Identity=24.0105540897098, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982612, Length=379, Percent_Identity=24.0105540897098, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71993915, Length=381, Percent_Identity=24.4094488188976, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=460, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71990446, Length=440, Percent_Identity=22.7272727272727, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982623, Length=256, Percent_Identity=26.5625, Blast_Score=85, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321492, Length=404, Percent_Identity=20.7920792079208, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550968, Length=450, Percent_Identity=26, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19921172, Length=450, Percent_Identity=26, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI221331183, Length=462, Percent_Identity=25.7575757575758, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17647653, Length=462, Percent_Identity=25.7575757575758, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24664379, Length=462, Percent_Identity=25.7575757575758, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24651635, Length=439, Percent_Identity=25.9681093394077, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24651633, Length=439, Percent_Identity=25.9681093394077, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21357367, Length=458, Percent_Identity=22.9257641921397, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641993, Length=405, Percent_Identity=25.679012345679, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24641995, Length=405, Percent_Identity=25.679012345679, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48163; Mature: 48032

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAEAHDSKRASRSGNTALPSVSLPVAIAIVIADMIGVGVFTSLGFQVKDLPSGFAILL
CCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHH
LWAVGGLVSICGALSYAELGTMFPRSSGEYNFLTRAFHPAVGFMAGWVSSTVGFAAPVAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMAFGEYGRAVLPSVPPMVLAVGAVWLVTVVQLGGIQQSSRFQLLSTMLKLGLILAFLI
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGAIISDPQPVRFAPAAADVGYITSAAFATGLVFVMYAFSGWNAATYIIGELHAPDHSLP
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCH
RALLVGTLIVIVLYVSLNAVFLRAAPTSELAGQLQVASIAGAHIFGETGGRFVAAMICVG
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCHHHHHHCHHHCCCCCHHHHHHHHHHH
LVPSIAAMMWIGPRVLMTMGEDIPALALFARRSRQGAPVYAVLFQLAVATLMLFTESFEA
HHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLDVVQFSLLSCSFLTVLGLLWLRITAPDLSRPYRAWGYPVTPLIFLSVTGFMMYYLVTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHC
RPWQAGFGAAAMLSGLLIYWFAQARSRTAAAAMSGPD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAAEAHDSKRASRSGNTALPSVSLPVAIAIVIADMIGVGVFTSLGFQVKDLPSGFAILL
CCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHH
LWAVGGLVSICGALSYAELGTMFPRSSGEYNFLTRAFHPAVGFMAGWVSSTVGFAAPVAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAMAFGEYGRAVLPSVPPMVLAVGAVWLVTVVQLGGIQQSSRFQLLSTMLKLGLILAFLI
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
AGAIISDPQPVRFAPAAADVGYITSAAFATGLVFVMYAFSGWNAATYIIGELHAPDHSLP
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCH
RALLVGTLIVIVLYVSLNAVFLRAAPTSELAGQLQVASIAGAHIFGETGGRFVAAMICVG
HHHHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCHHHHHHCHHHCCCCCHHHHHHHHHHH
LVPSIAAMMWIGPRVLMTMGEDIPALALFARRSRQGAPVYAVLFQLAVATLMLFTESFEA
HHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLDVVQFSLLSCSFLTVLGLLWLRITAPDLSRPYRAWGYPVTPLIFLSVTGFMMYYLVTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHC
RPWQAGFGAAAMLSGLLIYWFAQARSRTAAAAMSGPD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]