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The map label for this gene is cyaA [H]

Identifier: 146339870

GI number: 146339870

Start: 3071936

End: 3073246

Strand: Direct

Name: cyaA [H]

Synonym: BRADO2872

Alternate gene names: 146339870

Gene position: 3071936-3073246 (Clockwise)

Preceding gene: 146339869

Following gene: 146339871

Centisome position: 41.2

GC content: 64.0

Gene sequence:

>1311_bases
ATGCGGATCGCGAGGGCAGGCAAGGGGAGCGGTGCGCCACCCGCGGCGGCGGAGTTCAACCAGGCGCTGATGCGCCAGAC
GTTGAACACCGAGCTCTTGCGGGTGAAGGCGCTGATCGCCACGGCCGGACTGTTTCTGGTCATCTCGGTGTTCGTCGAGA
TCTTCGAGCCGCGGATCTCGGAGTGGATCTGGCCGAGCCGGGTCGGGGTCCTCTACGTCTACGCGATCATCGTCTCCTTC
ATCGCCTTCGAGCTGCTCATCCTGTTCAGGATCAAAGCCAACATCCGCCTCGGTCACGACGTCCCGATCGTGTTGCGGTA
TCTCAGCGTGCTGATCGAGACGTCGATGCCCACGCTCGTGCTGGTGTTGCAGATCGAAGGCATCGGCCGCGACAGGGCAC
TCGGCTTTGGCGCGCCGCTGGTCTATTTCATCTTCATCATCCTCTCGACCCTCCGTTTGGACTTCTGGCTGTCGAGCTTT
ACCGGACTGGTGGCAGCAGCGGAGTTGCTGACCGTCGCACTGATCGACAGACCCTCGATCGACATGAGCCAGCATCCGGA
GATCTACTATCAAGGCGAGCGCAGCTTCATCATCCTGCTGTGCGGTCTGCTCGCCGGCGCCGTCAGCGTGCAATTGCGCC
GGCAGTTCGCGGCGAGCATCGAGGCAGCCTCCGCGCGGGATCGGGTCACTGACCTGTTCGGCCAGCATGTCTCGCCCCAG
GTTGTCGAGCGGTTGATGAAGGAGGGCACGGCGGAGGCGCGGGACATCCAGAAGGTTGCCGTGATGTTCGTCGACTTCAG
AGGCTTCACCGCGGCTTCGCGTTCCAAACCGCCTCAGGAGGTCGTTGACCGGCTCGACGGTGCGTTTGCCGTGCTGGTCG
AGATCCTCGAGCGTCATGGCGGGATCGTGAACAAGTTTCTCGGGGACGGCTTCCTCGCGCTGTTCGGGGCGCCGTTCGAA
ACGCGCGACGCCGCAGCGCAGGCGGTCGCGGCGGCGCGCGAGATGGTAGCGGCCATGCGCGACGTCAATTCTGCCTCGTC
CTGGCCGCTGCGTATCGGCATCGGCATTCATCTCGGCGAGGTCGTGGCCGGCAGCATCGGCTCGCCGCGACGCAAGGAGT
ACACGGTCATCGGCGATACCGTGAACTTCGCCTCGCGGCTGGAGGCCTTGAACAAGGAGTTCGATTCGCAGCTCCTGATC
TCGACCGAGGTGCGGCAGGCCGCCGGTGAGGAGGCAGGGGATGCCGTCTTCCACGGCGAGGTATCAGTGCGCGGTTACGA
CCGGTCGTTCGAAGTCTGGCAGCTGCATTAA

Upstream 100 bases:

>100_bases
CGGTCTCATGCTGTTCGCCATGACGGTTGCCGTCTTCCGCTTCCGCCGCACGCTCGATTGAGGCACAATGCCGGTCGGGC
GGACAACCGGCTGAGGCAGG

Downstream 100 bases:

>100_bases
AGCCGATCGTTCACGTTGCTGCCGGCTGTGCGGCGTCGGCGATTTACATTGCCGGATCTCCACGCTTAACTGCGCGCCAA
TCAACAGGGTATCAGGAGGA

Product: putative adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRIARAGKGSGAPPAAAEFNQALMRQTLNTELLRVKALIATAGLFLVISVFVEIFEPRISEWIWPSRVGVLYVYAIIVSF
IAFELLILFRIKANIRLGHDVPIVLRYLSVLIETSMPTLVLVLQIEGIGRDRALGFGAPLVYFIFIILSTLRLDFWLSSF
TGLVAAAELLTVALIDRPSIDMSQHPEIYYQGERSFIILLCGLLAGAVSVQLRRQFAASIEAASARDRVTDLFGQHVSPQ
VVERLMKEGTAEARDIQKVAVMFVDFRGFTAASRSKPPQEVVDRLDGAFAVLVEILERHGGIVNKFLGDGFLALFGAPFE
TRDAAAQAVAAAREMVAAMRDVNSASSWPLRIGIGIHLGEVVAGSIGSPRRKEYTVIGDTVNFASRLEALNKEFDSQLLI
STEVRQAAGEEAGDAVFHGEVSVRGYDRSFEVWQLH

Sequences:

>Translated_436_residues
MRIARAGKGSGAPPAAAEFNQALMRQTLNTELLRVKALIATAGLFLVISVFVEIFEPRISEWIWPSRVGVLYVYAIIVSF
IAFELLILFRIKANIRLGHDVPIVLRYLSVLIETSMPTLVLVLQIEGIGRDRALGFGAPLVYFIFIILSTLRLDFWLSSF
TGLVAAAELLTVALIDRPSIDMSQHPEIYYQGERSFIILLCGLLAGAVSVQLRRQFAASIEAASARDRVTDLFGQHVSPQ
VVERLMKEGTAEARDIQKVAVMFVDFRGFTAASRSKPPQEVVDRLDGAFAVLVEILERHGGIVNKFLGDGFLALFGAPFE
TRDAAAQAVAAAREMVAAMRDVNSASSWPLRIGIGIHLGEVVAGSIGSPRRKEYTVIGDTVNFASRLEALNKEFDSQLLI
STEVRQAAGEEAGDAVFHGEVSVRGYDRSFEVWQLH
>Mature_436_residues
MRIARAGKGSGAPPAAAEFNQALMRQTLNTELLRVKALIATAGLFLVISVFVEIFEPRISEWIWPSRVGVLYVYAIIVSF
IAFELLILFRIKANIRLGHDVPIVLRYLSVLIETSMPTLVLVLQIEGIGRDRALGFGAPLVYFIFIILSTLRLDFWLSSF
TGLVAAAELLTVALIDRPSIDMSQHPEIYYQGERSFIILLCGLLAGAVSVQLRRQFAASIEAASARDRVTDLFGQHVSPQ
VVERLMKEGTAEARDIQKVAVMFVDFRGFTAASRSKPPQEVVDRLDGAFAVLVEILERHGGIVNKFLGDGFLALFGAPFE
TRDAAAQAVAAAREMVAAMRDVNSASSWPLRIGIGIHLGEVVAGSIGSPRRKEYTVIGDTVNFASRLEALNKEFDSQLLI
STEVRQAAGEEAGDAVFHGEVSVRGYDRSFEVWQLH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Homo sapiens, GI134152694, Length=215, Percent_Identity=28.8372093023256, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24497587, Length=284, Percent_Identity=25.7042253521127, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4557255, Length=226, Percent_Identity=25.6637168141593, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI167830411, Length=212, Percent_Identity=29.2452830188679, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI222080083, Length=174, Percent_Identity=30.4597701149425, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4504217, Length=185, Percent_Identity=30.2702702702703, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4580422, Length=210, Percent_Identity=28.0952380952381, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206632, Length=210, Percent_Identity=28.0952380952381, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534659, Length=177, Percent_Identity=31.638418079096, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193207841, Length=201, Percent_Identity=28.8557213930348, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193205840, Length=160, Percent_Identity=31.25, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982300, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561804, Length=212, Percent_Identity=28.3018867924528, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71989822, Length=218, Percent_Identity=25.2293577981651, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71989805, Length=218, Percent_Identity=25.2293577981651, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508769, Length=180, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17534657, Length=169, Percent_Identity=31.9526627218935, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534651, Length=207, Percent_Identity=29.951690821256, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534649, Length=261, Percent_Identity=25.6704980842912, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86564713, Length=159, Percent_Identity=29.559748427673, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534655, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994363, Length=160, Percent_Identity=29.375, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561794, Length=159, Percent_Identity=30.8176100628931, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193210669, Length=160, Percent_Identity=29.375, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71995300, Length=174, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995305, Length=205, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484298, Length=203, Percent_Identity=30.5418719211823, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI62484477, Length=203, Percent_Identity=30.5418719211823, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116008008, Length=211, Percent_Identity=29.8578199052133, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585694, Length=163, Percent_Identity=29.4478527607362, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281366459, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281366457, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281366455, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI56292422, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI56292424, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666940, Length=167, Percent_Identity=31.1377245508982, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161078020, Length=215, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330468, Length=167, Percent_Identity=28.7425149700599, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330470, Length=187, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574512, Length=167, Percent_Identity=27.5449101796407, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076872, Length=167, Percent_Identity=27.5449101796407, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62473752, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137448, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663839, Length=168, Percent_Identity=29.7619047619048, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24663843, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24642014, Length=342, Percent_Identity=21.9298245614035, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85725044, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 47862; Mature: 47862

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIARAGKGSGAPPAAAEFNQALMRQTLNTELLRVKALIATAGLFLVISVFVEIFEPRIS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWIWPSRVGVLYVYAIIVSFIAFELLILFRIKANIRLGHDVPIVLRYLSVLIETSMPTLV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCEE
LVLQIEGIGRDRALGFGAPLVYFIFIILSTLRLDFWLSSFTGLVAAAELLTVALIDRPSI
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DMSQHPEIYYQGERSFIILLCGLLAGAVSVQLRRQFAASIEAASARDRVTDLFGQHVSPQ
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVERLMKEGTAEARDIQKVAVMFVDFRGFTAASRSKPPQEVVDRLDGAFAVLVEILERHG
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCC
GIVNKFLGDGFLALFGAPFETRDAAAQAVAAAREMVAAMRDVNSASSWPLRIGIGIHLGE
CHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEHHH
VVAGSIGSPRRKEYTVIGDTVNFASRLEALNKEFDSQLLISTEVRQAAGEEAGDAVFHGE
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
VSVRGYDRSFEVWQLH
EEEEECCCCCEEEEEC
>Mature Secondary Structure
MRIARAGKGSGAPPAAAEFNQALMRQTLNTELLRVKALIATAGLFLVISVFVEIFEPRIS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWIWPSRVGVLYVYAIIVSFIAFELLILFRIKANIRLGHDVPIVLRYLSVLIETSMPTLV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCEE
LVLQIEGIGRDRALGFGAPLVYFIFIILSTLRLDFWLSSFTGLVAAAELLTVALIDRPSI
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DMSQHPEIYYQGERSFIILLCGLLAGAVSVQLRRQFAASIEAASARDRVTDLFGQHVSPQ
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVERLMKEGTAEARDIQKVAVMFVDFRGFTAASRSKPPQEVVDRLDGAFAVLVEILERHG
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCC
GIVNKFLGDGFLALFGAPFETRDAAAQAVAAAREMVAAMRDVNSASSWPLRIGIGIHLGE
CHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEEHHH
VVAGSIGSPRRKEYTVIGDTVNFASRLEALNKEFDSQLLISTEVRQAAGEEAGDAVFHGE
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
VSVRGYDRSFEVWQLH
EEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]