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The map label for this gene is hpcG [H]

Identifier: 146339603

GI number: 146339603

Start: 2779492

End: 2780298

Strand: Reverse

Name: hpcG [H]

Synonym: BRADO2595

Alternate gene names: 146339603

Gene position: 2780298-2779492 (Counterclockwise)

Preceding gene: 146339608

Following gene: 146339602

Centisome position: 37.29

GC content: 63.69

Gene sequence:

>807_bases
ATGCCGCTGTCGAGCGACCAGATTCACAGCTGCGCCTTGCGCCTGGATCAGGCCGAAAAATCTCGCCGTCAGATCCGGCA
ATTCTCGCAGGATTTTCCCGAGATCACGATCGCCGACGCCTACGCGATCCAGAAAGCCTGGATCGACATCAAGGTCGGCG
AAGGGCGGGTCATCAAGGGCCACAAGATCGGCCTGACGTCGAAGGCGATGCAGAACGCGCTGAACATCGACGAGCCGGAT
TCGGGCGTGCTGCTCGACGACATGTTCTTCGCCGATGGCGGCCTCGTGCCATCCGGCCGCTTCATTGCAACGCGGATCGA
GGCTGAGCTGGCCTTTGTCATGAAGCACCGGCTCGCCGGACCGGACTGCACATTGTTCGATGTGCTCAACGCGACCGACT
TCGTCGTGCCGGCGCTCGAGATCCTGGATACACGGATCGAGCGCGTCGATCCGGAGACCAAGGCGACGCGCAAGATCTTC
GACACGATCGCGGACAACGCGGCGAACGCCGGCATTGTCCTCGGCGGACGGCCGCTGCGGCCCGCCGACACCGACCTGCG
CTGGGTGGGCGCCCTCTGTTATAAGAACGGTCAGTTGGAGGAGACCGGCCTGGCTGCCGGAGTGCTTAACAACCCGGCAA
CCGCCGTCGCCTGGCTCGCCAACAAGATCGCAGCGCACGGGCTTGCACTTGAACCAGGCCAGGTGGTTCTCGCCGGGTCG
TTCATCCGGCCGATCGAGGCCCGCAAGGGCGACACGATCCAGGCCGACTACGGTCCGTATGGAACGGTGAGCTGCTATTT
CGCCTGA

Upstream 100 bases:

>100_bases
CCTTCCGATATTTGCACTGCAGCAATCGCCGTTTGGATTTGCGGCAATAAACTTAACATGTTAATCAACTGCCGCCACCT
GTTTCCTCGAGGATCCTCTC

Downstream 100 bases:

>100_bases
CGCCCTTGCCGGAGCTGAACCACCATGCCGCATTTCAGCATCGAGTACTCCGCCAATCTCGACGCCCGCGTCGACATGGC
CGGGATTTGCGAGATCGTTC

Product: 2-oxo-hepta-3-ene-1,7-dioate hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPLSSDQIHSCALRLDQAEKSRRQIRQFSQDFPEITIADAYAIQKAWIDIKVGEGRVIKGHKIGLTSKAMQNALNIDEPD
SGVLLDDMFFADGGLVPSGRFIATRIEAELAFVMKHRLAGPDCTLFDVLNATDFVVPALEILDTRIERVDPETKATRKIF
DTIADNAANAGIVLGGRPLRPADTDLRWVGALCYKNGQLEETGLAAGVLNNPATAVAWLANKIAAHGLALEPGQVVLAGS
FIRPIEARKGDTIQADYGPYGTVSCYFA

Sequences:

>Translated_268_residues
MPLSSDQIHSCALRLDQAEKSRRQIRQFSQDFPEITIADAYAIQKAWIDIKVGEGRVIKGHKIGLTSKAMQNALNIDEPD
SGVLLDDMFFADGGLVPSGRFIATRIEAELAFVMKHRLAGPDCTLFDVLNATDFVVPALEILDTRIERVDPETKATRKIF
DTIADNAANAGIVLGGRPLRPADTDLRWVGALCYKNGQLEETGLAAGVLNNPATAVAWLANKIAAHGLALEPGQVVLAGS
FIRPIEARKGDTIQADYGPYGTVSCYFA
>Mature_267_residues
PLSSDQIHSCALRLDQAEKSRRQIRQFSQDFPEITIADAYAIQKAWIDIKVGEGRVIKGHKIGLTSKAMQNALNIDEPDS
GVLLDDMFFADGGLVPSGRFIATRIEAELAFVMKHRLAGPDCTLFDVLNATDFVVPALEILDTRIERVDPETKATRKIFD
TIADNAANAGIVLGGRPLRPADTDLRWVGALCYKNGQLEETGLAAGVLNNPATAVAWLANKIAAHGLALEPGQVVLAGSF
IRPIEARKGDTIQADYGPYGTVSCYFA

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=229, Percent_Identity=34.4978165938865, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 29021; Mature: 28890

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSSDQIHSCALRLDQAEKSRRQIRQFSQDFPEITIADAYAIQKAWIDIKVGEGRVIKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHEEEEEEEEEEECCCEEECC
HKIGLTSKAMQNALNIDEPDSGVLLDDMFFADGGLVPSGRFIATRIEAELAFVMKHRLAG
CCCCCCHHHHHHHCCCCCCCCCEEEEHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCC
PDCTLFDVLNATDFVVPALEILDTRIERVDPETKATRKIFDTIADNAANAGIVLGGRPLR
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCC
PADTDLRWVGALCYKNGQLEETGLAAGVLNNPATAVAWLANKIAAHGLALEPGQVVLAGS
CCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCEEECCCCEEEECC
FIRPIEARKGDTIQADYGPYGTVSCYFA
CCCCHHCCCCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure 
PLSSDQIHSCALRLDQAEKSRRQIRQFSQDFPEITIADAYAIQKAWIDIKVGEGRVIKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHEEEEEEEEEEECCCEEECC
HKIGLTSKAMQNALNIDEPDSGVLLDDMFFADGGLVPSGRFIATRIEAELAFVMKHRLAG
CCCCCCHHHHHHHCCCCCCCCCEEEEHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCC
PDCTLFDVLNATDFVVPALEILDTRIERVDPETKATRKIFDTIADNAANAGIVLGGRPLR
CCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCC
PADTDLRWVGALCYKNGQLEETGLAAGVLNNPATAVAWLANKIAAHGLALEPGQVVLAGS
CCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCEEECCCCEEEECC
FIRPIEARKGDTIQADYGPYGTVSCYFA
CCCCHHCCCCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]