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The map label for this gene is gbpR [H]

Identifier: 146339287

GI number: 146339287

Start: 2411717

End: 2412664

Strand: Reverse

Name: gbpR [H]

Synonym: BRADO2263

Alternate gene names: 146339287

Gene position: 2412664-2411717 (Counterclockwise)

Preceding gene: 146339297

Following gene: 146339277

Centisome position: 32.36

GC content: 67.62

Gene sequence:

>948_bases
ATGAAGATCGACGAGCGTCACTTGGTCCAACTCGCCGCCGTGATCAATGCCGGCGGCGTGACCGAAGGCGCCGCGCTGCT
CGGCATGACGCAGCCGGCGGTCTCGCGCACGCTGGCCGCGCTGGAGAAGCGGCTTGGCGAGCCGCTGTTCGTGAAAGGCC
GCCGCCCGTTGCGCCCGACTCCATTCGGCCGGGCGCTCGCCGATCACGGCCAGGCCATGCTGCTCGCCTCACGCAAGGCG
TCCGAGCTGATCGACAACTTCCGCCACGGGCTGGCCGGGACCGTACGCGTCGCCGGAACACCGTTCTTCATGGACGGCCT
GATTTCCGGCCTGATCGCGGAATTCCACAACGCCCGTCCCGACGTGCGCGTGATCCAGAGCTACGGCTACATGCCGGAGC
TGCAGGAGGCGATCCGCGCCGATCGCATCGATCTCGCCATCTGCCCGGTCGACGTGCTCGACGGCGACGATCTCGAGTTC
CAATCGATCCTTCCCGGCCGCAACGTCGTCGCCTGCCGCGTCACCCATCCGCTGCTGATGAAGCGCAAGTTGAAGGGCCC
GGAGATTCTGGACTTCCCCTGGATCGCACCGCCGCCGAACAGCCCGCTGCAGGCCGACATGCGCGCGCTGCTGCTGTCGT
TCGGATCGACGGGCGTCAGCATGCCTTACGTGGGCGGCTCGCTGGCCAGCGCAATGAACTATCTCAAGCGCACCGACGCG
TTGACGATCCTGCCGCACGGTGTCGTCTTCGCCTACCGCAGGGACCGCGAGATCACCGCGCTGCCGCTGCGCGTGCCGCA
TCCGGAGCGCGCGCTCGGCATCCTCCGGCTGGCCGGCAGCCCGCAGTCTCCAGCGGTGATGGCGTTCGCAGCATCCATCG
CAGCCGGATTCGCAACACTCGCCGACCTCATCCGCCGTCACGAGCAATCCGTGATTTGGAAGGCCTAG

Upstream 100 bases:

>100_bases
GCATCGTCCCTCCCCGGAAACGTCGTCTGTTTTGAGGAACGGTAGCAGGACCCGCCAGGGGCGTTGATGATTTTTGCGCG
GGATAATATAGCAGATTGCT

Downstream 100 bases:

>100_bases
CAAAGGCTATCTGCCAAGTTCTCGAACTTATGCCGTCGGCATTCAACTCTCACAGCTTTGCAGCTATCTTCATATTCGTT
TCGCCTAAAGCGATGAGATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKIDERHLVQLAAVINAGGVTEGAALLGMTQPAVSRTLAALEKRLGEPLFVKGRRPLRPTPFGRALADHGQAMLLASRKA
SELIDNFRHGLAGTVRVAGTPFFMDGLISGLIAEFHNARPDVRVIQSYGYMPELQEAIRADRIDLAICPVDVLDGDDLEF
QSILPGRNVVACRVTHPLLMKRKLKGPEILDFPWIAPPPNSPLQADMRALLLSFGSTGVSMPYVGGSLASAMNYLKRTDA
LTILPHGVVFAYRRDREITALPLRVPHPERALGILRLAGSPQSPAVMAFAASIAAGFATLADLIRRHEQSVIWKA

Sequences:

>Translated_315_residues
MKIDERHLVQLAAVINAGGVTEGAALLGMTQPAVSRTLAALEKRLGEPLFVKGRRPLRPTPFGRALADHGQAMLLASRKA
SELIDNFRHGLAGTVRVAGTPFFMDGLISGLIAEFHNARPDVRVIQSYGYMPELQEAIRADRIDLAICPVDVLDGDDLEF
QSILPGRNVVACRVTHPLLMKRKLKGPEILDFPWIAPPPNSPLQADMRALLLSFGSTGVSMPYVGGSLASAMNYLKRTDA
LTILPHGVVFAYRRDREITALPLRVPHPERALGILRLAGSPQSPAVMAFAASIAAGFATLADLIRRHEQSVIWKA
>Mature_315_residues
MKIDERHLVQLAAVINAGGVTEGAALLGMTQPAVSRTLAALEKRLGEPLFVKGRRPLRPTPFGRALADHGQAMLLASRKA
SELIDNFRHGLAGTVRVAGTPFFMDGLISGLIAEFHNARPDVRVIQSYGYMPELQEAIRADRIDLAICPVDVLDGDDLEF
QSILPGRNVVACRVTHPLLMKRKLKGPEILDFPWIAPPPNSPLQADMRALLLSFGSTGVSMPYVGGSLASAMNYLKRTDA
LTILPHGVVFAYRRDREITALPLRVPHPERALGILRLAGSPQSPAVMAFAASIAAGFATLADLIRRHEQSVIWKA

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=279, Percent_Identity=24.0143369175627, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=25.7627118644068, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789204, Length=145, Percent_Identity=32.4137931034483, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=271, Percent_Identity=25.830258302583, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790262, Length=253, Percent_Identity=25.6916996047431, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34168; Mature: 34168

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDERHLVQLAAVINAGGVTEGAALLGMTQPAVSRTLAALEKRLGEPLFVKGRRPLRPT
CCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PFGRALADHGQAMLLASRKASELIDNFRHGLAGTVRVAGTPFFMDGLISGLIAEFHNARP
CCHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
DVRVIQSYGYMPELQEAIRADRIDLAICPVDVLDGDDLEFQSILPGRNVVACRVTHPLLM
CHHHHHHCCCCHHHHHHHHHCCCEEEECCEEECCCCCCCHHHCCCCCCEEEEECCCHHHH
KRKLKGPEILDFPWIAPPPNSPLQADMRALLLSFGSTGVSMPYVGGSLASAMNYLKRTDA
HHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
LTILPHGVVFAYRRDREITALPLRVPHPERALGILRLAGSPQSPAVMAFAASIAAGFATL
EEEECCCEEEEEECCCCEEEEEEECCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
ADLIRRHEQSVIWKA
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIDERHLVQLAAVINAGGVTEGAALLGMTQPAVSRTLAALEKRLGEPLFVKGRRPLRPT
CCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCC
PFGRALADHGQAMLLASRKASELIDNFRHGLAGTVRVAGTPFFMDGLISGLIAEFHNARP
CCHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
DVRVIQSYGYMPELQEAIRADRIDLAICPVDVLDGDDLEFQSILPGRNVVACRVTHPLLM
CHHHHHHCCCCHHHHHHHHHCCCEEEECCEEECCCCCCCHHHCCCCCCEEEEECCCHHHH
KRKLKGPEILDFPWIAPPPNSPLQADMRALLLSFGSTGVSMPYVGGSLASAMNYLKRTDA
HHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
LTILPHGVVFAYRRDREITALPLRVPHPERALGILRLAGSPQSPAVMAFAASIAAGFATL
EEEECCCEEEEEECCCCEEEEEEECCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
ADLIRRHEQSVIWKA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]