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The map label for this gene is potC [H]

Identifier: 146339153

GI number: 146339153

Start: 2244388

End: 2245233

Strand: Reverse

Name: potC [H]

Synonym: BRADO2111

Alternate gene names: 146339153

Gene position: 2245233-2244388 (Counterclockwise)

Preceding gene: 146339154

Following gene: 146339152

Centisome position: 30.11

GC content: 64.42

Gene sequence:

>846_bases
TTGGCCGCATCGATCGAACACACGGGCTCGCCGGCGTTGCGTGGCAGCAAGTCGCCGATCCGGTGGGGCCGCAAGCTCTA
TCTCGCAGCAAACATCGCGATCATTCTCTTCTTGCTCGCGCCAATCGCAATCGTGATCGTGTTCGCGCTGAACCCGACGC
CGTTCATCCAGTTTCCGCCGGTCGGCGTCTCGCTGCGCTGGTTCGAGAAGTTCTTCGCCTCGCGCGACTTCATGCATGCG
CTGTTGTTCAGCCTCGAGATCGCGGCGATGACGACAGTCGCATCCACCGTGCTCGGCGCGTCGGCGGCGCTCGCCATCGC
CCGCGGCAACCTGCCGGGCTCGCGGCTGATCGTGGCGACCGTGCTCTCGCCCTTGATGCTGCCGGCGATCCTCACCGGCC
TGGCGCTGTTCCAGTCCTACGTCCTGGTCGACATCGGCCGGCCGTTGTGGGGGCTGGTGGCGGGTCACACGCTGGTGACG
ATCCCCTATGTTGTTCGTACCACGCTTGCCGTGCTGCATAACTTCGATGTGCGGCTGGAGGAAGCCGCCCAGAATCTCGG
CGCGAGCCCGGCGCGGACGTTCTTCGAAGTCACCCTGCCCCTGGTGAAGCCGGGCGTGATGGCGGGCGCGATCTTCGCCT
TCATCGTCTCGTTCGACCAGTTTCCGGTGTCGCTGTTCCTGGTCGCTCCGGGCAGCGAGACCCTGCCGATCACGCTGTTC
AACTATCTCAAATTCGATCTCGACGGCACCATCGGCGCCGCCTCCGTCATTTCGATCCTCCTCGCCTTCATCGTCGTCAT
CGCGCTCGACCGCACCGTTGGCCTGCGGTCCACCGTCAAACTGTAA

Upstream 100 bases:

>100_bases
TGGTCATCGCCTACAATCACGTGCTTGGCCTCGTGTCGGGGCAGCGCGAGCTGCGATGAGGGCGCAGATGACGAGCCTTT
CCAAGGGATCGCAGCGTCCG

Downstream 100 bases:

>100_bases
GGGAGCTCCCGGATATGACCGCCTCATCGCGTCGCTTCCCCCTCAGCCGCCGCCGCCTGCTGACCGCGGCAGCTTCGCTC
GGCGCCGGCTTCGTCGCGGC

Product: putative ABC spermidine/putrescine transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MAASIEHTGSPALRGSKSPIRWGRKLYLAANIAIILFLLAPIAIVIVFALNPTPFIQFPPVGVSLRWFEKFFASRDFMHA
LLFSLEIAAMTTVASTVLGASAALAIARGNLPGSRLIVATVLSPLMLPAILTGLALFQSYVLVDIGRPLWGLVAGHTLVT
IPYVVRTTLAVLHNFDVRLEEAAQNLGASPARTFFEVTLPLVKPGVMAGAIFAFIVSFDQFPVSLFLVAPGSETLPITLF
NYLKFDLDGTIGAASVISILLAFIVVIALDRTVGLRSTVKL

Sequences:

>Translated_281_residues
MAASIEHTGSPALRGSKSPIRWGRKLYLAANIAIILFLLAPIAIVIVFALNPTPFIQFPPVGVSLRWFEKFFASRDFMHA
LLFSLEIAAMTTVASTVLGASAALAIARGNLPGSRLIVATVLSPLMLPAILTGLALFQSYVLVDIGRPLWGLVAGHTLVT
IPYVVRTTLAVLHNFDVRLEEAAQNLGASPARTFFEVTLPLVKPGVMAGAIFAFIVSFDQFPVSLFLVAPGSETLPITLF
NYLKFDLDGTIGAASVISILLAFIVVIALDRTVGLRSTVKL
>Mature_280_residues
AASIEHTGSPALRGSKSPIRWGRKLYLAANIAIILFLLAPIAIVIVFALNPTPFIQFPPVGVSLRWFEKFFASRDFMHAL
LFSLEIAAMTTVASTVLGASAALAIARGNLPGSRLIVATVLSPLMLPAILTGLALFQSYVLVDIGRPLWGLVAGHTLVTI
PYVVRTTLAVLHNFDVRLEEAAQNLGASPARTFFEVTLPLVKPGVMAGAIFAFIVSFDQFPVSLFLVAPGSETLPITLFN
YLKFDLDGTIGAASVISILLAFIVVIALDRTVGLRSTVKL

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=224, Percent_Identity=29.4642857142857, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787714, Length=210, Percent_Identity=34.7619047619048, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787081, Length=227, Percent_Identity=30.8370044052863, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786980, Length=209, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788764, Length=186, Percent_Identity=27.9569892473118, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30071; Mature: 29940

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASIEHTGSPALRGSKSPIRWGRKLYLAANIAIILFLLAPIAIVIVFALNPTPFIQFPP
CCCCCCCCCCCCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCC
VGVSLRWFEKFFASRDFMHALLFSLEIAAMTTVASTVLGASAALAIARGNLPGSRLIVAT
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHH
VLSPLMLPAILTGLALFQSYVLVDIGRPLWGLVAGHTLVTIPYVVRTTLAVLHNFDVRLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
EAAQNLGASPARTFFEVTLPLVKPGVMAGAIFAFIVSFDQFPVSLFLVAPGSETLPITLF
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
NYLKFDLDGTIGAASVISILLAFIVVIALDRTVGLRSTVKL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure 
AASIEHTGSPALRGSKSPIRWGRKLYLAANIAIILFLLAPIAIVIVFALNPTPFIQFPP
CCCCCCCCCCCCCCCCCCHHHCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCC
VGVSLRWFEKFFASRDFMHALLFSLEIAAMTTVASTVLGASAALAIARGNLPGSRLIVAT
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHH
VLSPLMLPAILTGLALFQSYVLVDIGRPLWGLVAGHTLVTIPYVVRTTLAVLHNFDVRLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
EAAQNLGASPARTFFEVTLPLVKPGVMAGAIFAFIVSFDQFPVSLFLVAPGSETLPITLF
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
NYLKFDLDGTIGAASVISILLAFIVVIALDRTVGLRSTVKL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]