Click here to switch to the map view.

The map label for this gene is hyuA [H]

Identifier: 146339149

GI number: 146339149

Start: 2239497

End: 2241050

Strand: Reverse

Name: hyuA [H]

Synonym: BRADO2107

Alternate gene names: 146339149

Gene position: 2241050-2239497 (Counterclockwise)

Preceding gene: 146339150

Following gene: 146339147

Centisome position: 30.05

GC content: 70.72

Gene sequence:

>1554_bases
ATGAAGCGGATTGGCATTGACGTCGGCGGCACCAACACCGACGCGGTCCTGATTGCCAACGACAAGGTCGTCCACTCGGT
CAAGGCCGCCACCACCGCCGACGTCACCTCCGGCATCCTCGCGGCGCTGAAGGCGCTGCGCGACAATCCCGCAGCGGCCG
TGCCTGTCGACGCGGTCGTGATCGGCACCACGCATTTCATCAACGCGGTGGTGCAGCGGCGGCATCTGCAAAGGATCGGC
GCCGTCAGGATCGGTATGCCCGCCTCCGCCTCGCTGCCGCCGTTCTGCGACTGGCCGGCGGACCTTGCCGACCTCGTCAG
CGGCGAGACGTTCATGCTGGAGGGCGGCCATGACTATGACGGACGCCCCTTCATGCCGCTCGACATCGACGGCCTGAAAG
CCGCCGCGCGCGCGATCAAGGCCAAGGGGCTGCGCGCTGTCGCAGTCGCCTCTTCGTTCTCGCCGCTCGATCCGAGCTGC
GAGATCACCGCGCACGAAATCTTCGCCGAGATCTGCCCCGACGTCGCGGTCACGCTGTCGCACCACCTCGGCCGCATCGG
CCTGCTCGAGCGCGAGAACGCTGCGCTCCTCAACGCCGCGCTCCACGACCTCGCCGTCACCACCGTCGCCGCTTTCCGCA
AGGCGATCGCGGATTCCGGCATCGATGCGCCGCTGTTCCTGACGCAGAACGACGGCACCGTGATGCAGGCGGAGATCGCG
ACCGCCTTCCCGGTCATGAGCTTCGCCTCCGGCGCCACCAATTCGATGCGCGGCGCCGCGTATCTCTCCGGCCTCGACGA
CGCCATGGTGGTGGACGTCGGCGGCACCACCTCCGACATCGGCCAGCTGCGCCACGGCTTTCCGCGCGAGGCGAATGCCG
TGGTCGAGGTCGGCGGCGTCCGCACCCTGTTCCGCATGCCCGACCTGCTGTCGATCGGCCTGGGCGGCGGCAGCCACGTC
GCGCGCGAGCCGGTGCGCGTCGGCCCGGTCAGCGTCGGATATCGGCTCACCACCGACGCGATGGTGTTCGGCGGCGGCCA
GCTCACCGCGACCGACATCGCGGTGGCGGCCGGGCTGATCGACATCGGCGACCGCGCGCGCGTCGCGCATCTGCCGAAGA
GCCTGATCGATGCCGCGCTCGCTGACGCCCATCGCCAGCTCGAGGGCGACATCGACCGCATGAAGACCGAGGCCGGCGAC
GTGCCGCTGCTCGCGGTCGGCGGCGGCGCGTTCCTCGTGCCGGCGCGGCTCGCCGGCATCTCCGAAATCGTCCGCGTGCC
CCATGGCGACTGCGCCAATGCGGTCGGCGCGGCGATCGCGCAAGTGTCGGGCGAGGCCGACCAGGTGTTCCGCGACATGA
CCCGCGACGAGGCCATCGCGGCTGCCCGCCGCATCGCCGAGGAGCGCGCGGTGCAGGCGGGCGCCGAACGCGGCTCGCTC
AAGACGGTCGACGTCGAGGATATGCCGATCGCCTACCTCCCCGGCAATGCACTCCGTGTCCGCGTCCGCGTCGCCGGCGC
CATCGCCGAGCCCGACATCGATGCGGCGGCGTAG

Upstream 100 bases:

>100_bases
CGTGCTGACCAGCCCGCGCGGCCTGGAGTTCGTGGGCCCCCGCGCCTTCGGGTACGACCTCGATTTCCGGTCGCTGTTTG
CGACCTCCGGAGCAGAGTGA

Downstream 100 bases:

>100_bases
CTCAGCCGCATCGCCAGCCTCACCATCTCATCTCACACGAGCTCCGCGATCCGCTCCACGCCGGCCTCCGCGCCTTGCGC
CTTGGCCGCTGCCATCGAGC

Product: putative hydantoinase A

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKRIGIDVGGTNTDAVLIANDKVVHSVKAATTADVTSGILAALKALRDNPAAAVPVDAVVIGTTHFINAVVQRRHLQRIG
AVRIGMPASASLPPFCDWPADLADLVSGETFMLEGGHDYDGRPFMPLDIDGLKAAARAIKAKGLRAVAVASSFSPLDPSC
EITAHEIFAEICPDVAVTLSHHLGRIGLLERENAALLNAALHDLAVTTVAAFRKAIADSGIDAPLFLTQNDGTVMQAEIA
TAFPVMSFASGATNSMRGAAYLSGLDDAMVVDVGGTTSDIGQLRHGFPREANAVVEVGGVRTLFRMPDLLSIGLGGGSHV
AREPVRVGPVSVGYRLTTDAMVFGGGQLTATDIAVAAGLIDIGDRARVAHLPKSLIDAALADAHRQLEGDIDRMKTEAGD
VPLLAVGGGAFLVPARLAGISEIVRVPHGDCANAVGAAIAQVSGEADQVFRDMTRDEAIAAARRIAEERAVQAGAERGSL
KTVDVEDMPIAYLPGNALRVRVRVAGAIAEPDIDAAA

Sequences:

>Translated_517_residues
MKRIGIDVGGTNTDAVLIANDKVVHSVKAATTADVTSGILAALKALRDNPAAAVPVDAVVIGTTHFINAVVQRRHLQRIG
AVRIGMPASASLPPFCDWPADLADLVSGETFMLEGGHDYDGRPFMPLDIDGLKAAARAIKAKGLRAVAVASSFSPLDPSC
EITAHEIFAEICPDVAVTLSHHLGRIGLLERENAALLNAALHDLAVTTVAAFRKAIADSGIDAPLFLTQNDGTVMQAEIA
TAFPVMSFASGATNSMRGAAYLSGLDDAMVVDVGGTTSDIGQLRHGFPREANAVVEVGGVRTLFRMPDLLSIGLGGGSHV
AREPVRVGPVSVGYRLTTDAMVFGGGQLTATDIAVAAGLIDIGDRARVAHLPKSLIDAALADAHRQLEGDIDRMKTEAGD
VPLLAVGGGAFLVPARLAGISEIVRVPHGDCANAVGAAIAQVSGEADQVFRDMTRDEAIAAARRIAEERAVQAGAERGSL
KTVDVEDMPIAYLPGNALRVRVRVAGAIAEPDIDAAA
>Mature_517_residues
MKRIGIDVGGTNTDAVLIANDKVVHSVKAATTADVTSGILAALKALRDNPAAAVPVDAVVIGTTHFINAVVQRRHLQRIG
AVRIGMPASASLPPFCDWPADLADLVSGETFMLEGGHDYDGRPFMPLDIDGLKAAARAIKAKGLRAVAVASSFSPLDPSC
EITAHEIFAEICPDVAVTLSHHLGRIGLLERENAALLNAALHDLAVTTVAAFRKAIADSGIDAPLFLTQNDGTVMQAEIA
TAFPVMSFASGATNSMRGAAYLSGLDDAMVVDVGGTTSDIGQLRHGFPREANAVVEVGGVRTLFRMPDLLSIGLGGGSHV
AREPVRVGPVSVGYRLTTDAMVFGGGQLTATDIAVAAGLIDIGDRARVAHLPKSLIDAALADAHRQLEGDIDRMKTEAGD
VPLLAVGGGAFLVPARLAGISEIVRVPHGDCANAVGAAIAQVSGEADQVFRDMTRDEAIAAARRIAEERAVQAGAERGSL
KTVDVEDMPIAYLPGNALRVRVRVAGAIAEPDIDAAA

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 53535; Mature: 53535

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIGIDVGGTNTDAVLIANDKVVHSVKAATTADVTSGILAALKALRDNPAAAVPVDAVV
CCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
IGTTHFINAVVQRRHLQRIGAVRIGMPASASLPPFCDWPADLADLVSGETFMLEGGHDYD
ECHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCC
GRPFMPLDIDGLKAAARAIKAKGLRAVAVASSFSPLDPSCEITAHEIFAEICPDVAVTLS
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
HHLGRIGLLERENAALLNAALHDLAVTTVAAFRKAIADSGIDAPLFLTQNDGTVMQAEIA
HHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEHHH
TAFPVMSFASGATNSMRGAAYLSGLDDAMVVDVGGTTSDIGQLRHGFPREANAVVEVGGV
HHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCH
RTLFRMPDLLSIGLGGGSHVAREPVRVGPVSVGYRLTTDAMVFGGGQLTATDIAVAAGLI
HHHHHCCCCEEEECCCCCHHHCCCCEECCEEECEEEECCEEEECCCCEEHHHHHHHHHHH
DIGDRARVAHLPKSLIDAALADAHRQLEGDIDRMKTEAGDVPLLAVGGGAFLVPARLAGI
CCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCEEEHHHHHHHH
SEIVRVPHGDCANAVGAAIAQVSGEADQVFRDMTRDEAIAAARRIAEERAVQAGAERGSL
HHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
KTVDVEDMPIAYLPGNALRVRVRVAGAIAEPDIDAAA
EEEECCCCCEEEECCCEEEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKRIGIDVGGTNTDAVLIANDKVVHSVKAATTADVTSGILAALKALRDNPAAAVPVDAVV
CCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
IGTTHFINAVVQRRHLQRIGAVRIGMPASASLPPFCDWPADLADLVSGETFMLEGGHDYD
ECHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCC
GRPFMPLDIDGLKAAARAIKAKGLRAVAVASSFSPLDPSCEITAHEIFAEICPDVAVTLS
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
HHLGRIGLLERENAALLNAALHDLAVTTVAAFRKAIADSGIDAPLFLTQNDGTVMQAEIA
HHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEHHH
TAFPVMSFASGATNSMRGAAYLSGLDDAMVVDVGGTTSDIGQLRHGFPREANAVVEVGGV
HHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCH
RTLFRMPDLLSIGLGGGSHVAREPVRVGPVSVGYRLTTDAMVFGGGQLTATDIAVAAGLI
HHHHHCCCCEEEECCCCCHHHCCCCEECCEEECEEEECCEEEECCCCEEHHHHHHHHHHH
DIGDRARVAHLPKSLIDAALADAHRQLEGDIDRMKTEAGDVPLLAVGGGAFLVPARLAGI
CCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCEEEHHHHHHHH
SEIVRVPHGDCANAVGAAIAQVSGEADQVFRDMTRDEAIAAARRIAEERAVQAGAERGSL
HHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
KTVDVEDMPIAYLPGNALRVRVRVAGAIAEPDIDAAA
EEEECCCCCEEEECCCEEEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]