BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is cmtB [H]

Identifier: 146339144

GI number: 146339144

Start: 2234549

End: 2235319

Strand: Reverse

Name: cmtB [H]

Synonym: BRADO2099

Alternate gene names: 146339144

Gene position: 2235319-2234549 (Counterclockwise)

Preceding gene: 146339147

Following gene: 146339143

Centisome position: 29.98

GC content: 67.57

Gene sequence:

>771_bases
GTGGCGCAAGTGGTCGTGATCAGTGGCGGCGGCACCGGCATCGGGCTTGCGACGGCGCGGACCTTCGCTGGACGTGGAGC
ACAGGTCGTGATGGTGGGACGCCGCAAAAGCGTGATCGAGGCCTCGGCCGCGTCGATCGCCGCTGAGCAGCCGCATGCGC
CGGCTCCCTTGGCCATCACGGCGGACCTTGCGGAGGTGGAGCAGGTCGAAGCAACACGAATGACGCTGGAGCAGCGGTTC
GCGGCCGTCGACGTACTGGTGAATGCTGCCGGCGGCCATGTGGCGCGGCGTGCGCCGACCAACACCTATGATGACGGTCT
GGCGGGCGTGGCGCGGCGCTGGACCGACAATTTCCGCATCAACACGCTGACGGCCGTGCTGCTCACCGAAGCGCTCATGC
CGCGCCTGCGTGCGCCGGGCGGACGGATCATCTTCGTGAGTTCGATCGCGGCCTATCGCGGATCGGGCGAAGGGTCTTAT
GGCGCGGCCAAGGCAGCACTGCACCCCTACTCCGCCGATCTCGCCAAACGGCTCGGACCACGCGGCATCACGGTGAACGT
CGTCGCGCCGGGCTATGTCGCGGACACGGAATTCTTCGGCGCGGCGATGAGTGAAGCACAGCTGAAATCGAGGATCGATG
AGACGATGAACGGCCGCGCGGGGACGCCCGACGACATCGCCGCGACGATCGGCTGGCTCGCCTCGGCGGAGGCGGTGCAT
GTCACCGCGCAGATCGTTCAGGTGAATGGCGGGGCCGAACGGGGGCATTAA

Upstream 100 bases:

>100_bases
AACTGCGTCCAGCCGCTCGCACGCGGTCGCCGCGGCCGGTTGTTGCTGCGCTGCCCAGGCCGGATCATCCCGACGTCGAG
TGAGATCTTGGAGTTGAAGC

Downstream 100 bases:

>100_bases
GGCAAACGGCTTGCGAGTTCGATTCGCCGCCGTAGGCAGGGACTGCAAGTGGATGCACGTACCAGTCACATAGCGAAGCT
ACGCTCAACGAGTCCTGGTT

Product: putative 3-oxacyl-ACP reductase

Products: NA

Alternate protein names: Biphenyl-2,3-dihydro-2,3-diol dehydrogenase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAQVVVISGGGTGIGLATARTFAGRGAQVVMVGRRKSVIEASAASIAAEQPHAPAPLAITADLAEVEQVEATRMTLEQRF
AAVDVLVNAAGGHVARRAPTNTYDDGLAGVARRWTDNFRINTLTAVLLTEALMPRLRAPGGRIIFVSSIAAYRGSGEGSY
GAAKAALHPYSADLAKRLGPRGITVNVVAPGYVADTEFFGAAMSEAQLKSRIDETMNGRAGTPDDIAATIGWLASAEAVH
VTAQIVQVNGGAERGH

Sequences:

>Translated_256_residues
MAQVVVISGGGTGIGLATARTFAGRGAQVVMVGRRKSVIEASAASIAAEQPHAPAPLAITADLAEVEQVEATRMTLEQRF
AAVDVLVNAAGGHVARRAPTNTYDDGLAGVARRWTDNFRINTLTAVLLTEALMPRLRAPGGRIIFVSSIAAYRGSGEGSY
GAAKAALHPYSADLAKRLGPRGITVNVVAPGYVADTEFFGAAMSEAQLKSRIDETMNGRAGTPDDIAATIGWLASAEAVH
VTAQIVQVNGGAERGH
>Mature_255_residues
AQVVVISGGGTGIGLATARTFAGRGAQVVMVGRRKSVIEASAASIAAEQPHAPAPLAITADLAEVEQVEATRMTLEQRFA
AVDVLVNAAGGHVARRAPTNTYDDGLAGVARRWTDNFRINTLTAVLLTEALMPRLRAPGGRIIFVSSIAAYRGSGEGSYG
AAKAALHPYSADLAKRLGPRGITVNVVAPGYVADTEFFGAAMSEAQLKSRIDETMNGRAGTPDDIAATIGWLASAEAVHV
TAQIVQVNGGAERGH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=29.2490118577075, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40254992, Length=259, Percent_Identity=30.8880308880309, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=26.953125, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI59889578, Length=242, Percent_Identity=28.9256198347107, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=31.5, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=28.2442748091603, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI225579078, Length=213, Percent_Identity=31.4553990610329, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.6772908366534, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=29.4820717131474, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=27.5590551181102, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=31.6793893129771, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=31.4741035856574, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=28.957528957529, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=28.0632411067194, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788459, Length=261, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=27.1653543307087, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=29.7619047619048, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=30.03663003663, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=29.9242424242424, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=27.734375, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=29.8850574712644, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=31.2977099236641, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=30.5019305019305, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.5343511450382, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.7984790874525, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=27.843137254902, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=30.4511278195489, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.2442748091603, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=32.3308270676692, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=31.4814814814815, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=24.5059288537549, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=29.277566539924, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=30.6930693069307, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=228, Percent_Identity=26.7543859649123, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=28.3464566929134, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=29.277566539924, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=232, Percent_Identity=26.2931034482759, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.1960784313725, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=28.740157480315, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=192, Percent_Identity=32.2916666666667, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=30.7392996108949, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.58 [H]

Molecular weight: Translated: 26471; Mature: 26340

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVVVISGGGTGIGLATARTFAGRGAQVVMVGRRKSVIEASAASIAAEQPHAPAPLAIT
CCEEEEEECCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEE
ADLAEVEQVEATRMTLEQRFAAVDVLVNAAGGHVARRAPTNTYDDGLAGVARRWTDNFRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCH
NTLTAVLLTEALMPRLRAPGGRIIFVSSIAAYRGSGEGSYGAAKAALHPYSADLAKRLGP
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHCCCCHHHHHHHCCC
RGITVNVVAPGYVADTEFFGAAMSEAQLKSRIDETMNGRAGTPDDIAATIGWLASAEAVH
CCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEE
VTAQIVQVNGGAERGH
EEEEEEEECCCCCCCC
>Mature Secondary Structure 
AQVVVISGGGTGIGLATARTFAGRGAQVVMVGRRKSVIEASAASIAAEQPHAPAPLAIT
CEEEEEECCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEE
ADLAEVEQVEATRMTLEQRFAAVDVLVNAAGGHVARRAPTNTYDDGLAGVARRWTDNFRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCH
NTLTAVLLTEALMPRLRAPGGRIIFVSSIAAYRGSGEGSYGAAKAALHPYSADLAKRLGP
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHCCCCHHHHHHHCCC
RGITVNVVAPGYVADTEFFGAAMSEAQLKSRIDETMNGRAGTPDDIAATIGWLASAEAVH
CCEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEE
VTAQIVQVNGGAERGH
EEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631713 [H]