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The map label for this gene is htpX [H]

Identifier: 146339043

GI number: 146339043

Start: 2119844

End: 2121022

Strand: Reverse

Name: htpX [H]

Synonym: BRADO1996

Alternate gene names: 146339043

Gene position: 2121022-2119844 (Counterclockwise)

Preceding gene: 146339044

Following gene: 146339041

Centisome position: 28.44

GC content: 67.43

Gene sequence:

>1179_bases
ATGGCCGCCTACGGTCTCTACACCCATATCGCATCGAACAAGACCCGTTCGATGGTGCTGCTCGGCGGCCTGTTCCTGCT
GATCTACGTGCTGGTGTTCGCCGGCGCACTGATCGCGGAGGTGATGATCAACGGCAATGGCAGCGTCGCCTACTACATGC
ACGCCGCCACCCGCGACCTGATCAAGGCGCTGCCCTGGGCCACCCTGGGCGCGGCGACCTGGATCGTGATCGCCTATTTC
TTCCACCAGAAGATGATCGACGCGGTGACCGGCGGCGCGGCGGTGACCCGCCAGGAGCAGCCGCGGCTGTACAATCTGCT
CGAAAATCTCTGCATCTCCCGCGGCATCACCATGCCGCAGCTGAAGATCATGGACAGCCCGGCGCTGAACGCGTTCGCGA
CCGGCCTCAACCCGCGGCAATATTCGGTCACCGTCACCACAGGCCTTCTCGCGGCGCTCGACGACCAGGAGATCGAGGCG
GTGCTGGGTCACGAGCTGACCCACATCCGCAACGGCGACGTCCAGCTGATGGTGGTCGCTGTCATCATCGCCGGCGTGGT
CGGCTTCTTCGGCGAATTGTTCTTCCGCCTGTTCACCAACATGAGCTGGGGCGGCGGCTGGGGCCGCTCGTCCTCTTCCT
CGTCGTCGGATTCCGACCGCAAGGGCTCCGGCGGCGGCGCGATCGTCGTGGTGCTGATTGCGGTAGTGCTGATCGTGGTG
GCCTGGCTGATGTCCCAGGTCGTCAAGCTGGCGCTGTCGCGCACCCGGGAATACCTCGCTGACGCGGGCTCCGTGGAGCT
GACCAAGAACCCGGACGCGATGATCAGCGCGCTGCGCAAAATCGAGGGGCGCGGCGAACTGCCCGGCGCGACCTCGGCGG
TGATGGAGCTGTGCGTCGACAATCCGCGCGAGGGCTTTGCCGATCTGTTCGCCACCCATCCCTCCGTCGAGTCCCGCGTC
CAGGCGCTGATCAAGTTCGCGGGGGGCCACGATCCCGGCCCGCTGGCGCTGCCTTCGGACGAGGCGGAGGAGAACGATAC
CGGTCCCGAAGCTGCCGATGGCGCGGGCCCTCCGTCGTTGCCGCCGGCGGGTCCCTGGAGCCATGCCGGTGATCCCGGCG
CATCGCCCGGCTCGACGGCGGAAGGCGGCCCGTGGAGCACGCCGGCCGCGGGCCCATAG

Upstream 100 bases:

>100_bases
CAAGGAATTCTTCGATCTCGGCACCAGCCGCGCCGAGGTCGAAGCGGCCCCGAGCGTCAAGTTCTGAGCCCGCGTCCTCC
CCGCTGAAGGGCCCGACGCC

Downstream 100 bases:

>100_bases
GGCAGGCACTAGACCTCGGTGCCCTGCTCCAATCCGGGACAAAAGTCGACCGTCGTCTTGCCAGTCGCTCTCAGCTGCTT
CCGCATCACAGCCTGGCTTT

Product: putative protease htpX membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAAYGLYTHIASNKTRSMVLLGGLFLLIYVLVFAGALIAEVMINGNGSVAYYMHAATRDLIKALPWATLGAATWIVIAYF
FHQKMIDAVTGGAAVTRQEQPRLYNLLENLCISRGITMPQLKIMDSPALNAFATGLNPRQYSVTVTTGLLAALDDQEIEA
VLGHELTHIRNGDVQLMVVAVIIAGVVGFFGELFFRLFTNMSWGGGWGRSSSSSSSDSDRKGSGGGAIVVVLIAVVLIVV
AWLMSQVVKLALSRTREYLADAGSVELTKNPDAMISALRKIEGRGELPGATSAVMELCVDNPREGFADLFATHPSVESRV
QALIKFAGGHDPGPLALPSDEAEENDTGPEAADGAGPPSLPPAGPWSHAGDPGASPGSTAEGGPWSTPAAGP

Sequences:

>Translated_392_residues
MAAYGLYTHIASNKTRSMVLLGGLFLLIYVLVFAGALIAEVMINGNGSVAYYMHAATRDLIKALPWATLGAATWIVIAYF
FHQKMIDAVTGGAAVTRQEQPRLYNLLENLCISRGITMPQLKIMDSPALNAFATGLNPRQYSVTVTTGLLAALDDQEIEA
VLGHELTHIRNGDVQLMVVAVIIAGVVGFFGELFFRLFTNMSWGGGWGRSSSSSSSDSDRKGSGGGAIVVVLIAVVLIVV
AWLMSQVVKLALSRTREYLADAGSVELTKNPDAMISALRKIEGRGELPGATSAVMELCVDNPREGFADLFATHPSVESRV
QALIKFAGGHDPGPLALPSDEAEENDTGPEAADGAGPPSLPPAGPWSHAGDPGASPGSTAEGGPWSTPAAGP
>Mature_391_residues
AAYGLYTHIASNKTRSMVLLGGLFLLIYVLVFAGALIAEVMINGNGSVAYYMHAATRDLIKALPWATLGAATWIVIAYFF
HQKMIDAVTGGAAVTRQEQPRLYNLLENLCISRGITMPQLKIMDSPALNAFATGLNPRQYSVTVTTGLLAALDDQEIEAV
LGHELTHIRNGDVQLMVVAVIIAGVVGFFGELFFRLFTNMSWGGGWGRSSSSSSSDSDRKGSGGGAIVVVLIAVVLIVVA
WLMSQVVKLALSRTREYLADAGSVELTKNPDAMISALRKIEGRGELPGATSAVMELCVDNPREGFADLFATHPSVESRVQ
ALIKFAGGHDPGPLALPSDEAEENDTGPEAADGAGPPSLPPAGPWSHAGDPGASPGSTAEGGPWSTPAAGP

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=231, Percent_Identity=34.1991341991342, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 41145; Mature: 41013

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYGLYTHIASNKTRSMVLLGGLFLLIYVLVFAGALIAEVMINGNGSVAYYMHAATRDL
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHH
IKALPWATLGAATWIVIAYFFHQKMIDAVTGGAAVTRQEQPRLYNLLENLCISRGITMPQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCC
LKIMDSPALNAFATGLNPRQYSVTVTTGLLAALDDQEIEAVLGHELTHIRNGDVQLMVVA
EEECCCCCHHHHHCCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VIIAGVVGFFGELFFRLFTNMSWGGGWGRSSSSSSSDSDRKGSGGGAIVVVLIAVVLIVV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AWLMSQVVKLALSRTREYLADAGSVELTKNPDAMISALRKIEGRGELPGATSAVMELCVD
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NPREGFADLFATHPSVESRVQALIKFAGGHDPGPLALPSDEAEENDTGPEAADGAGPPSL
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAGPWSHAGDPGASPGSTAEGGPWSTPAAGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAYGLYTHIASNKTRSMVLLGGLFLLIYVLVFAGALIAEVMINGNGSVAYYMHAATRDL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHH
IKALPWATLGAATWIVIAYFFHQKMIDAVTGGAAVTRQEQPRLYNLLENLCISRGITMPQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCC
LKIMDSPALNAFATGLNPRQYSVTVTTGLLAALDDQEIEAVLGHELTHIRNGDVQLMVVA
EEECCCCCHHHHHCCCCCCEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VIIAGVVGFFGELFFRLFTNMSWGGGWGRSSSSSSSDSDRKGSGGGAIVVVLIAVVLIVV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AWLMSQVVKLALSRTREYLADAGSVELTKNPDAMISALRKIEGRGELPGATSAVMELCVD
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NPREGFADLFATHPSVESRVQALIKFAGGHDPGPLALPSDEAEENDTGPEAADGAGPPSL
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPAGPWSHAGDPGASPGSTAEGGPWSTPAAGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA