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The map label for this gene is yafC [H]

Identifier: 146338914

GI number: 146338914

Start: 1979867

End: 1980772

Strand: Direct

Name: yafC [H]

Synonym: BRADO1854

Alternate gene names: 146338914

Gene position: 1979867-1980772 (Clockwise)

Preceding gene: 146338912

Following gene: 146338917

Centisome position: 26.55

GC content: 67.0

Gene sequence:

>906_bases
ATGAAGTGGCGGATTGAAGATATTCCGGTTTTTCATGCCGTCGTGGCGGACGGCGGCATGACCGGCGCCGCGCGCACCCT
CGGCATGCCGAAATCCTCGGTCAGCAAGTCGGTCGCCCGGCTGGAGCAGGACCTCGGCATCCGCCTGTTCGACCGCAACT
CGCGCCGCGTCCGTGTGACCCGTGAGGGCGAGCTGTTCTTCCAGCAGTGCCAGAAGATCCTTGACCAGGTGTCGGAGGCC
GATGCGGTCATGACCGGGCTGGTCGGCGTGCCCAGCGGCCGGCTGTCGGTAGCGCTGCCGCCGGCCTTTTGCGAGGAGAT
TTTGGCGCCGAACCTCGCCGAATTCCATCGCCGCTATCCGCGCATCGAGCTCGACATCGAGGCGCTCACGCGGTCGGTCG
ACATGCTGGCCGACCGCTTCGACATTGCGGTCGTCGTCGGCGTGCAGGAGGATTCCGAGCTGGCGCAGAAGGTCCTGATC
GGCGGCCGGCTGATCTGGGTGACCAGCCCGGCCTATCTTGCCGCGCACGACATCGGCGACGACCTGCGCGCGCTGGAACA
TCATCTCCTGATCTGCGAGCGCCGCTACGGCGATCGCACCTTGACGGTCAAGCAGCACGGCCACCTCGTGCGCTTCGACG
TCGGCCCTCAGGTCACGCGCATCAACAATCCGGTGGCGGTGCGGCGCGCGGTCGCCCATGGCGCGGGCCTGTCGTTCCTG
CCGGAGCATTATTGCGTGGAGTTGCTCAGCGAGGGGCGTCTGGTCGAGATCGGCAAGGACGTCGTGTTCGACACCCGCGC
CGCGCAGCTCACCGCGATCTTCCCGAGCCGCAAGCTGATCTCCTCGCGCGCCCGCGCTTTCCTGGATTTTCTCGAGGAGA
TCTGCGCTGCGCCTGCCCGCGGCTGA

Upstream 100 bases:

>100_bases
GCGCAGCCGCACGGGGCCGGACTATTACGAAGTTCCGCTGGCGAGACAATAATGCTAGCGTGTACGGATCGTTTCTACCT
ATGGACGAGTTACGCGCGCG

Downstream 100 bases:

>100_bases
GGCGGCCGATCACGGAGCTCAGGGCGTGGCGAACAGCCGGGCCCAATTGCTGAACGGACGCAGCGCAATCAGCTGGAGCG
TGAAGGATCCTTCGTGAATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKWRIEDIPVFHAVVADGGMTGAARTLGMPKSSVSKSVARLEQDLGIRLFDRNSRRVRVTREGELFFQQCQKILDQVSEA
DAVMTGLVGVPSGRLSVALPPAFCEEILAPNLAEFHRRYPRIELDIEALTRSVDMLADRFDIAVVVGVQEDSELAQKVLI
GGRLIWVTSPAYLAAHDIGDDLRALEHHLLICERRYGDRTLTVKQHGHLVRFDVGPQVTRINNPVAVRRAVAHGAGLSFL
PEHYCVELLSEGRLVEIGKDVVFDTRAAQLTAIFPSRKLISSRARAFLDFLEEICAAPARG

Sequences:

>Translated_301_residues
MKWRIEDIPVFHAVVADGGMTGAARTLGMPKSSVSKSVARLEQDLGIRLFDRNSRRVRVTREGELFFQQCQKILDQVSEA
DAVMTGLVGVPSGRLSVALPPAFCEEILAPNLAEFHRRYPRIELDIEALTRSVDMLADRFDIAVVVGVQEDSELAQKVLI
GGRLIWVTSPAYLAAHDIGDDLRALEHHLLICERRYGDRTLTVKQHGHLVRFDVGPQVTRINNPVAVRRAVAHGAGLSFL
PEHYCVELLSEGRLVEIGKDVVFDTRAAQLTAIFPSRKLISSRARAFLDFLEEICAAPARG
>Mature_301_residues
MKWRIEDIPVFHAVVADGGMTGAARTLGMPKSSVSKSVARLEQDLGIRLFDRNSRRVRVTREGELFFQQCQKILDQVSEA
DAVMTGLVGVPSGRLSVALPPAFCEEILAPNLAEFHRRYPRIELDIEALTRSVDMLADRFDIAVVVGVQEDSELAQKVLI
GGRLIWVTSPAYLAAHDIGDDLRALEHHLLICERRYGDRTLTVKQHGHLVRFDVGPQVTRINNPVAVRRAVAHGAGLSFL
PEHYCVELLSEGRLVEIGKDVVFDTRAAQLTAIFPSRKLISSRARAFLDFLEEICAAPARG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=26.578073089701, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=29.5302013422819, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789639, Length=253, Percent_Identity=26.4822134387352, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789173, Length=287, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787128, Length=315, Percent_Identity=25.3968253968254, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789440, Length=301, Percent_Identity=23.2558139534884, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=24.3243243243243, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=29.3103448275862, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787589, Length=301, Percent_Identity=24.9169435215947, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786448, Length=175, Percent_Identity=30.2857142857143, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790262, Length=124, Percent_Identity=31.4516129032258, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=24.406779661017, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082132, Length=298, Percent_Identity=25.8389261744966, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=28.4552845528455, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=122, Percent_Identity=31.9672131147541, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=122, Percent_Identity=31.9672131147541, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33382; Mature: 33382

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWRIEDIPVFHAVVADGGMTGAARTLGMPKSSVSKSVARLEQDLGIRLFDRNSRRVRVT
CCCCCCCCCEEEHEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
REGELFFQQCQKILDQVSEADAVMTGLVGVPSGRLSVALPPAFCEEILAPNLAEFHRRYP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCHHHHHHHCC
RIELDIEALTRSVDMLADRFDIAVVVGVQEDSELAQKVLIGGRLIWVTSPAYLAAHDIGD
CEEEEHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCEEEEEECCHHEEHHHCCH
DLRALEHHLLICERRYGDRTLTVKQHGHLVRFDVGPQVTRINNPVAVRRAVAHGAGLSFL
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCEEECCCCHHHHHHHHHCCCCCCC
PEHYCVELLSEGRLVEIGKDVVFDTRAAQLTAIFPSRKLISSRARAFLDFLEEICAAPAR
HHHHHHHHHCCCCEEEECCCCEEECCHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
G
C
>Mature Secondary Structure
MKWRIEDIPVFHAVVADGGMTGAARTLGMPKSSVSKSVARLEQDLGIRLFDRNSRRVRVT
CCCCCCCCCEEEHEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
REGELFFQQCQKILDQVSEADAVMTGLVGVPSGRLSVALPPAFCEEILAPNLAEFHRRYP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCHHHHHHHCC
RIELDIEALTRSVDMLADRFDIAVVVGVQEDSELAQKVLIGGRLIWVTSPAYLAAHDIGD
CEEEEHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCEEEEEECCHHEEHHHCCH
DLRALEHHLLICERRYGDRTLTVKQHGHLVRFDVGPQVTRINNPVAVRRAVAHGAGLSFL
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCEEECCCCHHHHHHHHHCCCCCCC
PEHYCVELLSEGRLVEIGKDVVFDTRAAQLTAIFPSRKLISSRARAFLDFLEEICAAPAR
HHHHHHHHHCCCCEEEECCCCEEECCHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]