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The map label for this gene is luxQ [H]

Identifier: 146338894

GI number: 146338894

Start: 1959112

End: 1961475

Strand: Direct

Name: luxQ [H]

Synonym: BRADO1833

Alternate gene names: 146338894

Gene position: 1959112-1961475 (Clockwise)

Preceding gene: 146338893

Following gene: 146338895

Centisome position: 26.27

GC content: 64.64

Gene sequence:

>2364_bases
ATGAGACCGGCCGACACCGGCGAAACCGGAGGACAGCCGTCCGCCTGCCTCGACGGCGGCCGGCGGCCGGCCCCGGCTGC
GGCCGAGCCGCGCGCAAGGATGTGGACGATTGGCACGTCCGTGGCGATGGCCTCCGCCATGATCATGGCGGTCGAGCAGA
TCACGGATCTGAAGCAGGACTGGATCGTCTCGCTGCTGATGCTGGCGATCGCGGCGATCATCATCATGGCTGTCTTGACG
TCGATGCTGATCCGCAACAGCGCGCAGGCCAGGGCGATGACGCAGGCCCTGACGCGCCAGAACGAGCAGTTGGCGCAGAC
CACGAAGCTCCTCAACGAAGCCCAGCGAATCGGCCGTCTCGGCCACTGGATGACGGCGGAAGGCGACGCGGCGGTCTGGT
CCGAGGAGCTGTTCGAGATCACCGGCCTGGAGCCGTTGTCCAGCGTCTCCTTCAGCAAGATGATCGAGATCATCCATCCG
GAGGATGTCGGGACCTACATCCGCGCAAGGGATCGCACGCTGAAGACGGGCTGCGCGCTGAAGCAGGACCTTCGCGTCAT
TCGCCCGGATGGCGAGATCCGTTGGATCAGGATCGTGGCAGATCCCATCGACGACGTCGACGGCCGGTTCCGCGAGCGCT
TCGGCATCGTTCAGGACATCACTGAGCGAAAGCAGGCGGAGGTCGCCGCCGATCAGGCACAGCAGCTGCTGCTCGATGCG
ATCGAGGCGCTGACGAAGGGATTCGTGCTGTTCGACAAGGATGATCGATTTGTCCTCTCGAACACGCGGTTTCGCGAGAT
GTTTCCCGGTTGGGCCACCTTGATGCGGCCCGGCATCTCGTTCACTGACCTGATGCGCAAGGCGCATGACCACGGGCTGG
TGCGTCCGAAGGGCGACGGCTTCGAGGATTGGCTCGAGCGCAAGCGCGCCTGGCATCTCGGCGGCAGCCGCATGATCGAG
CATCGCGAGATCAATGGACGCTGGATCCAGAGCGTCGACCATCGCATCTCCGATGGCGGCACCGTCTGCCTCGTGACAGA
TATCACCGCCTTCAAGACGGTTCAGGCCGAGCTCGAGCAGAAGCTTGCTTATGTGCAGGCGATCCGCTCGGATCTCGAGG
AGCAGAAGCGCGAGCTCGAGGCCACGGGGGCCGAGCTGCGCGCCGCGCGCGACGCCGCGGAGGCCGCCAACCGCGCCAAG
TCCGATTTCCTGGCGATCATGAGCCACGAGATCAGGACGCCGCTGAGCGGCATGGTCGGCATGGTCGATCTGCTGCGCGG
CACCTCGCTCAACGACGAGCAGAAACGCTACACGTCGCTCGCCAAGGAATCCGCGGATCTGCTGCTCCAGGTGATCAACG
ACATCCTCGATTTCTCCAAGCTCGAGGCGGGGAAATTGAAGTCCGAATGCATCGATTTCGACGTTCCGAGCCTGGTCGAG
AGCGCGGTGTCGTTCATGGGAGAGAAGGCCAGGAGACGCGGCCTCGACCTCAAGGTGAGCTTTGCGCCGGGCCTGCCGCA
ATATCTCGAGGGCGATCCGACCCGCATCCGCCAAGTGATGCTGAACCTCGTCGGCAACGCCATCAAGTTCACCGAACAGG
GCGCGATCGAGGTGCACGCCTCTCACCGCGAGCTCGACGACGGTGCGGTCGATCTCAGGATCGAGGTCATCGACAGCGGC
ATCGGCATGTCTCAGGAGATCCAGGCTCAGATCTTCGATCCCTTCGTCCAGGCCGACACCTCGATCTCGCGCAAATACGG
CGGCAGCGGACTTGGCCTTGCGATCTGCAAGCAGCTCTGCGCCATCATGGGCGGCAGCATCGGCGTCGAGAGCGAGCCTG
GCCGCGGCAGCCGCTTCTGGTTCGAAGCCAGGTGCCAGCGGGGTGAAGCCCTGGCTCTGCCCGCCGAGACGGTCATCGAG
GCGGTCGACCGCCCGCTCGAGATCCTCGTCGCCGAGGACAGTCCGATCATCGCGACCCTGATCAACAGCCTGCTGGTCAA
GCAGGGCTTCAAGCCGACCATGGTCGGCAACGGCAGCAAGGCGGTCGCGGCAGTTTCGCAGAAGTCATACGATCTCGTCC
TCATGGACGTGCAGATGCCCGAGATGGACGGCATCTCCGCGACCGAGGCCATCCGGCGGCTGCCGGGCCCGGAGCGCCAC
GTCCCGATTATCGCGTTGACGGCCAATGCGCTGGTGGGACAGCGCGAGACCTATCTTGCTGCCGGCATGAACGACTATGT
CACCAAGCCGATCCAGCCGGCCCTCTTGTTCGCGGCGATCCGCCGCTGGGCCCTGCCGCAATATGCAGATGCACCGCCGC
TGCAGTCGGGCGGGGTCAGCCAGCTCGAGATGTTCGTGTCCTGA

Upstream 100 bases:

>100_bases
TCGACCTGACCACGCCTGAGGAGATCACAGCGCATCTGCCGCTTCTGAGCGAGACGATCGGCGTCACGACCGACGAGCTC
TCGCGCGTGGCGGATCGCGT

Downstream 100 bases:

>100_bases
CGCCGTTCGTCGCGCCGATTGTGAGCGGTGGTGCGCGACGAAAAGTGCTTCGCAGGCCTGGAGCAGACGCAAAAGTAAAA
TTTGCTACATCCGGTGCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MRPADTGETGGQPSACLDGGRRPAPAAAEPRARMWTIGTSVAMASAMIMAVEQITDLKQDWIVSLLMLAIAAIIIMAVLT
SMLIRNSAQARAMTQALTRQNEQLAQTTKLLNEAQRIGRLGHWMTAEGDAAVWSEELFEITGLEPLSSVSFSKMIEIIHP
EDVGTYIRARDRTLKTGCALKQDLRVIRPDGEIRWIRIVADPIDDVDGRFRERFGIVQDITERKQAEVAADQAQQLLLDA
IEALTKGFVLFDKDDRFVLSNTRFREMFPGWATLMRPGISFTDLMRKAHDHGLVRPKGDGFEDWLERKRAWHLGGSRMIE
HREINGRWIQSVDHRISDGGTVCLVTDITAFKTVQAELEQKLAYVQAIRSDLEEQKRELEATGAELRAARDAAEAANRAK
SDFLAIMSHEIRTPLSGMVGMVDLLRGTSLNDEQKRYTSLAKESADLLLQVINDILDFSKLEAGKLKSECIDFDVPSLVE
SAVSFMGEKARRRGLDLKVSFAPGLPQYLEGDPTRIRQVMLNLVGNAIKFTEQGAIEVHASHRELDDGAVDLRIEVIDSG
IGMSQEIQAQIFDPFVQADTSISRKYGGSGLGLAICKQLCAIMGGSIGVESEPGRGSRFWFEARCQRGEALALPAETVIE
AVDRPLEILVAEDSPIIATLINSLLVKQGFKPTMVGNGSKAVAAVSQKSYDLVLMDVQMPEMDGISATEAIRRLPGPERH
VPIIALTANALVGQRETYLAAGMNDYVTKPIQPALLFAAIRRWALPQYADAPPLQSGGVSQLEMFVS

Sequences:

>Translated_787_residues
MRPADTGETGGQPSACLDGGRRPAPAAAEPRARMWTIGTSVAMASAMIMAVEQITDLKQDWIVSLLMLAIAAIIIMAVLT
SMLIRNSAQARAMTQALTRQNEQLAQTTKLLNEAQRIGRLGHWMTAEGDAAVWSEELFEITGLEPLSSVSFSKMIEIIHP
EDVGTYIRARDRTLKTGCALKQDLRVIRPDGEIRWIRIVADPIDDVDGRFRERFGIVQDITERKQAEVAADQAQQLLLDA
IEALTKGFVLFDKDDRFVLSNTRFREMFPGWATLMRPGISFTDLMRKAHDHGLVRPKGDGFEDWLERKRAWHLGGSRMIE
HREINGRWIQSVDHRISDGGTVCLVTDITAFKTVQAELEQKLAYVQAIRSDLEEQKRELEATGAELRAARDAAEAANRAK
SDFLAIMSHEIRTPLSGMVGMVDLLRGTSLNDEQKRYTSLAKESADLLLQVINDILDFSKLEAGKLKSECIDFDVPSLVE
SAVSFMGEKARRRGLDLKVSFAPGLPQYLEGDPTRIRQVMLNLVGNAIKFTEQGAIEVHASHRELDDGAVDLRIEVIDSG
IGMSQEIQAQIFDPFVQADTSISRKYGGSGLGLAICKQLCAIMGGSIGVESEPGRGSRFWFEARCQRGEALALPAETVIE
AVDRPLEILVAEDSPIIATLINSLLVKQGFKPTMVGNGSKAVAAVSQKSYDLVLMDVQMPEMDGISATEAIRRLPGPERH
VPIIALTANALVGQRETYLAAGMNDYVTKPIQPALLFAAIRRWALPQYADAPPLQSGGVSQLEMFVS
>Mature_787_residues
MRPADTGETGGQPSACLDGGRRPAPAAAEPRARMWTIGTSVAMASAMIMAVEQITDLKQDWIVSLLMLAIAAIIIMAVLT
SMLIRNSAQARAMTQALTRQNEQLAQTTKLLNEAQRIGRLGHWMTAEGDAAVWSEELFEITGLEPLSSVSFSKMIEIIHP
EDVGTYIRARDRTLKTGCALKQDLRVIRPDGEIRWIRIVADPIDDVDGRFRERFGIVQDITERKQAEVAADQAQQLLLDA
IEALTKGFVLFDKDDRFVLSNTRFREMFPGWATLMRPGISFTDLMRKAHDHGLVRPKGDGFEDWLERKRAWHLGGSRMIE
HREINGRWIQSVDHRISDGGTVCLVTDITAFKTVQAELEQKLAYVQAIRSDLEEQKRELEATGAELRAARDAAEAANRAK
SDFLAIMSHEIRTPLSGMVGMVDLLRGTSLNDEQKRYTSLAKESADLLLQVINDILDFSKLEAGKLKSECIDFDVPSLVE
SAVSFMGEKARRRGLDLKVSFAPGLPQYLEGDPTRIRQVMLNLVGNAIKFTEQGAIEVHASHRELDDGAVDLRIEVIDSG
IGMSQEIQAQIFDPFVQADTSISRKYGGSGLGLAICKQLCAIMGGSIGVESEPGRGSRFWFEARCQRGEALALPAETVIE
AVDRPLEILVAEDSPIIATLINSLLVKQGFKPTMVGNGSKAVAAVSQKSYDLVLMDVQMPEMDGISATEAIRRLPGPERH
VPIIALTANALVGQRETYLAAGMNDYVTKPIQPALLFAAIRRWALPQYADAPPLQSGGVSQLEMFVS

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=44.2687747035573, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788713, Length=371, Percent_Identity=36.9272237196765, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI48994928, Length=392, Percent_Identity=34.9489795918367, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081816, Length=381, Percent_Identity=35.9580052493438, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=42.9824561403509, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=30.5309734513274, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=254, Percent_Identity=32.6771653543307, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=28.0334728033473, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=28.0487804878049, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=27.9279279279279, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=257, Percent_Identity=27.2373540856031, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=28.3842794759825, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=23.7903225806452, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788394, Length=114, Percent_Identity=30.7017543859649, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=115, Percent_Identity=32.1739130434783, Blast_Score=63, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=70, Percent_Identity=50, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322000, Length=118, Percent_Identity=34.7457627118644, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86658; Mature: 86658

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPADTGETGGQPSACLDGGRRPAPAAAEPRARMWTIGTSVAMASAMIMAVEQITDLKQD
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
WIVSLLMLAIAAIIIMAVLTSMLIRNSAQARAMTQALTRQNEQLAQTTKLLNEAQRIGRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHWMTAEGDAAVWSEELFEITGLEPLSSVSFSKMIEIIHPEDVGTYIRARDRTLKTGCAL
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
KQDLRVIRPDGEIRWIRIVADPIDDVDGRFRERFGIVQDITERKQAEVAADQAQQLLLDA
HHCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALTKGFVLFDKDDRFVLSNTRFREMFPGWATLMRPGISFTDLMRKAHDHGLVRPKGDG
HHHHHCCCEEECCCCCEEECCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
FEDWLERKRAWHLGGSRMIEHREINGRWIQSVDHRISDGGTVCLVTDITAFKTVQAELEQ
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
KLAYVQAIRSDLEEQKRELEATGAELRAARDAAEAANRAKSDFLAIMSHEIRTPLSGMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MVDLLRGTSLNDEQKRYTSLAKESADLLLQVINDILDFSKLEAGKLKSECIDFDVPSLVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
SAVSFMGEKARRRGLDLKVSFAPGLPQYLEGDPTRIRQVMLNLVGNAIKFTEQGAIEVHA
HHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEC
SHRELDDGAVDLRIEVIDSGIGMSQEIQAQIFDPFVQADTSISRKYGGSGLGLAICKQLC
CCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
AIMGGSIGVESEPGRGSRFWFEARCQRGEALALPAETVIEAVDRPLEILVAEDSPIIATL
HHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCHHHHHHHHCCCEEEEEECCCCHHHHH
INSLLVKQGFKPTMVGNGSKAVAAVSQKSYDLVLMDVQMPEMDGISATEAIRRLPGPERH
HHHHHHHCCCCCCEECCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCC
VPIIALTANALVGQRETYLAAGMNDYVTKPIQPALLFAAIRRWALPQYADAPPLQSGGVS
CCEEEEECCHHHCCCHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QLEMFVS
HHHHHCC
>Mature Secondary Structure
MRPADTGETGGQPSACLDGGRRPAPAAAEPRARMWTIGTSVAMASAMIMAVEQITDLKQD
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
WIVSLLMLAIAAIIIMAVLTSMLIRNSAQARAMTQALTRQNEQLAQTTKLLNEAQRIGRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHWMTAEGDAAVWSEELFEITGLEPLSSVSFSKMIEIIHPEDVGTYIRARDRTLKTGCAL
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
KQDLRVIRPDGEIRWIRIVADPIDDVDGRFRERFGIVQDITERKQAEVAADQAQQLLLDA
HHCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEALTKGFVLFDKDDRFVLSNTRFREMFPGWATLMRPGISFTDLMRKAHDHGLVRPKGDG
HHHHHCCCEEECCCCCEEECCCHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
FEDWLERKRAWHLGGSRMIEHREINGRWIQSVDHRISDGGTVCLVTDITAFKTVQAELEQ
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
KLAYVQAIRSDLEEQKRELEATGAELRAARDAAEAANRAKSDFLAIMSHEIRTPLSGMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MVDLLRGTSLNDEQKRYTSLAKESADLLLQVINDILDFSKLEAGKLKSECIDFDVPSLVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
SAVSFMGEKARRRGLDLKVSFAPGLPQYLEGDPTRIRQVMLNLVGNAIKFTEQGAIEVHA
HHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEC
SHRELDDGAVDLRIEVIDSGIGMSQEIQAQIFDPFVQADTSISRKYGGSGLGLAICKQLC
CCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
AIMGGSIGVESEPGRGSRFWFEARCQRGEALALPAETVIEAVDRPLEILVAEDSPIIATL
HHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEECCHHHHHHHHCCCEEEEEECCCCHHHHH
INSLLVKQGFKPTMVGNGSKAVAAVSQKSYDLVLMDVQMPEMDGISATEAIRRLPGPERH
HHHHHHHCCCCCCEECCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCC
VPIIALTANALVGQRETYLAAGMNDYVTKPIQPALLFAAIRRWALPQYADAPPLQSGGVS
CCEEEEECCHHHCCCHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QLEMFVS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]