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The map label for this gene is siaT [H]

Identifier: 146338780

GI number: 146338780

Start: 1829479

End: 1831362

Strand: Direct

Name: siaT [H]

Synonym: BRADO1714

Alternate gene names: 146338780

Gene position: 1829479-1831362 (Clockwise)

Preceding gene: 146338779

Following gene: 146338781

Centisome position: 24.54

GC content: 67.04

Gene sequence:

>1884_bases
ATGACCATGCAGCTCGTTGACCACTCCAGTGCAGCCGTCCTTCCCGCAACCGGGCACGCGTCCATCGCACGCGTGCTCGA
GCGGGCGCTCGGCGCGGTCGTCTCGACCGCGGCGGCGCTGCTCGTCGTCGCCGAGATCGGCGTGCTGTTCGCGGGCGTCT
GCGCCCGCTACGTCTTCCACAAGCCGCTGATCTGGTCGGACGAGCTCGCCGGCATCCTCTTTCTGTGGCTCGCCATGCTC
GGGGCCGCCGTCGCGTTCCAGCGCGGCGAGCACATGCGCATGACGGCGGCTGTTGGACGGCTGTCGAGCCAGATGCAGTC
GTTCCTCGATGTGCTCGCGATCGCCGCCCCGCTCGCCTTCCTCATCCTCGTCATCGATCCCGCCTATGAGTTCGCCGCCG
ACGAAGCGATCATCACCACGCCGGCGCTGGAATTGTCCAACCTTTGGCGCGCGGCGGCGCTGCCGACCGGGCTCGGCATC
ATGCTGGTCATGGCCGTGCTGCGGCTGTGCACGCTCGGCGAATGGAAGCTGGTCGGCGGCGCCGCGCTGCTGATCGGCGC
GATCGGCATTGGCTTGTATCTCCTTGGGCCGGCGCTGATCCCGCTCGGCAACCTCAATCTCCTGATCTTCTTCGTCGGCC
TTGTCGCGCTCCTGGTGTTCGCCGCCGTGCCGATCGCCTTCGCCTTCGGCCTCGCCACCTTCGCCTACATCACCTTGACC
ACGAACACGCCGTCGACGGTGGTGATCGGCCGCATGGACGAGGGCATGAGCCATCTCATTCTGCTCTCTGTGCCGCTGTT
CGTCTTCCTCGGCCTCCTGATCGAGATGACCGGCATGGCGCGGGCGATGGTCGGCTTCCTCGCGAGCCTGCTCGGCCATG
TCCGCGGCGGCCTGCAATATGTGCTGGTCGCAGCGATGTATCTCGTCTCCGGCATTTCCGGCTCCAAGGCCGCCGACATG
GCCGCGGTCGCGCCGGTGCTGTTTCCGGAAATGGTCAAGCGCGGCGCCAAGCCCGGCGATCTCGTGGCGCTGTTGTCGGC
GACCGGTGCGCAGACCGAGACCATCCCGCCGAGTCTCGTGCTCATCACGATCGGCTCGGTCACCGGCGTGTCGATCGCGG
CGCTGTTCACCGGCGGCCTGCTGCCTGGCCTGGTGCTCGCCTTCATGCTGTGCGTCGTGGTCTGGCAGCGCTATCGCGGC
GAGGACCTGTCGCATGTCAGCAAGGCCAGCCTGGGCATGATCGCGAAGAGCTTCGTCATCGCGCTCCCGGCTGTGGCGCT
GCCTTTCATCATCCGCGCTGCCGTGGTCGGCGGCGTCGCGACCGCGACCGAAGTCTCGACCATCGGCATCGTCTACTCCG
CACTGTGTGGCCTCCTGCTGTATCGCCGCTTCGACTGGCGCCGGCTGGCATCGATGCTGATCGAGACCGCGGCGCTGTCA
GGCGCGATCCTGCTGATCATCGGCGCCGCCACCGGCATGGCCTGGGCGCTGACGCAGTCCGGCTTTTCCACCGCGCTGGC
GCGCTTCATGACCAATCTGCCGGGTGGCGCGCCGATGTTCCTGGCTGTCACCATCGCGGCCTTCATCGTGCTCGGCAGCG
TGCTCGAAGGCATCCCGGCGATCGTGCTGTTCGGCCCGCTGCTGTTTCCGATCGCCAAGCAGATCGGCATCCACGAGGTG
CATTACGCGATGGTGGTGATCCTGGCGATGGGCATCGGCCTGTTCGCGCCGCCGTTCGGTGTCGGCTACTACGCCGCGTG
CGCGATCAGCCGGATTCATCCGGATATGGGGATCAGGCCGATGCTCGGCTACACTCTGGCGCTGCTGATCGGCACGATCG
TGATCGCGGCGGTGCCGTGGTTCTCGATCGGCCTTTTGCACTGA

Upstream 100 bases:

>100_bases
AAGGACGCCAAGGCCAAGTTCGGCGACGAGGCGTGGTCGCTGCTGCAGCGCTACGCTGGCAATATCAGCTGACCTCAACC
CCGGTTGCGGATGTCGGGCC

Downstream 100 bases:

>100_bases
TCCTTCGGCATATCAAGAGGTGAGGGGAACGACCATGAGGGATCTCTTGAATTTCGGCCAGATGCTATCGGCTCACGCGC
GCATGTCGCCGGAGCGCACC

Product: TRAP-type C4-dicarboxylate transporter small and large permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MTMQLVDHSSAAVLPATGHASIARVLERALGAVVSTAAALLVVAEIGVLFAGVCARYVFHKPLIWSDELAGILFLWLAML
GAAVAFQRGEHMRMTAAVGRLSSQMQSFLDVLAIAAPLAFLILVIDPAYEFAADEAIITTPALELSNLWRAAALPTGLGI
MLVMAVLRLCTLGEWKLVGGAALLIGAIGIGLYLLGPALIPLGNLNLLIFFVGLVALLVFAAVPIAFAFGLATFAYITLT
TNTPSTVVIGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVGFLASLLGHVRGGLQYVLVAAMYLVSGISGSKAADM
AAVAPVLFPEMVKRGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGLVLAFMLCVVVWQRYRG
EDLSHVSKASLGMIAKSFVIALPAVALPFIIRAAVVGGVATATEVSTIGIVYSALCGLLLYRRFDWRRLASMLIETAALS
GAILLIIGAATGMAWALTQSGFSTALARFMTNLPGGAPMFLAVTIAAFIVLGSVLEGIPAIVLFGPLLFPIAKQIGIHEV
HYAMVVILAMGIGLFAPPFGVGYYAACAISRIHPDMGIRPMLGYTLALLIGTIVIAAVPWFSIGLLH

Sequences:

>Translated_627_residues
MTMQLVDHSSAAVLPATGHASIARVLERALGAVVSTAAALLVVAEIGVLFAGVCARYVFHKPLIWSDELAGILFLWLAML
GAAVAFQRGEHMRMTAAVGRLSSQMQSFLDVLAIAAPLAFLILVIDPAYEFAADEAIITTPALELSNLWRAAALPTGLGI
MLVMAVLRLCTLGEWKLVGGAALLIGAIGIGLYLLGPALIPLGNLNLLIFFVGLVALLVFAAVPIAFAFGLATFAYITLT
TNTPSTVVIGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVGFLASLLGHVRGGLQYVLVAAMYLVSGISGSKAADM
AAVAPVLFPEMVKRGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGLVLAFMLCVVVWQRYRG
EDLSHVSKASLGMIAKSFVIALPAVALPFIIRAAVVGGVATATEVSTIGIVYSALCGLLLYRRFDWRRLASMLIETAALS
GAILLIIGAATGMAWALTQSGFSTALARFMTNLPGGAPMFLAVTIAAFIVLGSVLEGIPAIVLFGPLLFPIAKQIGIHEV
HYAMVVILAMGIGLFAPPFGVGYYAACAISRIHPDMGIRPMLGYTLALLIGTIVIAAVPWFSIGLLH
>Mature_626_residues
TMQLVDHSSAAVLPATGHASIARVLERALGAVVSTAAALLVVAEIGVLFAGVCARYVFHKPLIWSDELAGILFLWLAMLG
AAVAFQRGEHMRMTAAVGRLSSQMQSFLDVLAIAAPLAFLILVIDPAYEFAADEAIITTPALELSNLWRAAALPTGLGIM
LVMAVLRLCTLGEWKLVGGAALLIGAIGIGLYLLGPALIPLGNLNLLIFFVGLVALLVFAAVPIAFAFGLATFAYITLTT
NTPSTVVIGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVGFLASLLGHVRGGLQYVLVAAMYLVSGISGSKAADMA
AVAPVLFPEMVKRGAKPGDLVALLSATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGLVLAFMLCVVVWQRYRGE
DLSHVSKASLGMIAKSFVIALPAVALPFIIRAAVVGGVATATEVSTIGIVYSALCGLLLYRRFDWRRLASMLIETAALSG
AILLIIGAATGMAWALTQSGFSTALARFMTNLPGGAPMFLAVTIAAFIVLGSVLEGIPAIVLFGPLLFPIAKQIGIHEVH
YAMVVILAMGIGLFAPPFGVGYYAACAISRIHPDMGIRPMLGYTLALLIGTIVIAAVPWFSIGLLH

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=346, Percent_Identity=28.0346820809249, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 65383; Mature: 65252

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQLVDHSSAAVLPATGHASIARVLERALGAVVSTAAALLVVAEIGVLFAGVCARYVFH
CCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLIWSDELAGILFLWLAMLGAAVAFQRGEHMRMTAAVGRLSSQMQSFLDVLAIAAPLAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILVIDPAYEFAADEAIITTPALELSNLWRAAALPTGLGIMLVMAVLRLCTLGEWKLVGG
HHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHH
AALLIGAIGIGLYLLGPALIPLGNLNLLIFFVGLVALLVFAAVPIAFAFGLATFAYITLT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TNTPSTVVIGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVGFLASLLGHVRGGLQY
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVAAMYLVSGISGSKAADMAAVAPVLFPEMVKRGAKPGDLVALLSATGAQTETIPPSLV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEE
LITIGSVTGVSIAALFTGGLLPGLVLAFMLCVVVWQRYRGEDLSHVSKASLGMIAKSFVI
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALPAVALPFIIRAAVVGGVATATEVSTIGIVYSALCGLLLYRRFDWRRLASMLIETAALS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GAILLIIGAATGMAWALTQSGFSTALARFMTNLPGGAPMFLAVTIAAFIVLGSVLEGIPA
CHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVLFGPLLFPIAKQIGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAISRIHPDMGIRP
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCH
MLGYTLALLIGTIVIAAVPWFSIGLLH
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TMQLVDHSSAAVLPATGHASIARVLERALGAVVSTAAALLVVAEIGVLFAGVCARYVFH
CEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLIWSDELAGILFLWLAMLGAAVAFQRGEHMRMTAAVGRLSSQMQSFLDVLAIAAPLAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILVIDPAYEFAADEAIITTPALELSNLWRAAALPTGLGIMLVMAVLRLCTLGEWKLVGG
HHHHHCCHHHHHCCCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHH
AALLIGAIGIGLYLLGPALIPLGNLNLLIFFVGLVALLVFAAVPIAFAFGLATFAYITLT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TNTPSTVVIGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVGFLASLLGHVRGGLQY
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVAAMYLVSGISGSKAADMAAVAPVLFPEMVKRGAKPGDLVALLSATGAQTETIPPSLV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCEE
LITIGSVTGVSIAALFTGGLLPGLVLAFMLCVVVWQRYRGEDLSHVSKASLGMIAKSFVI
EEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ALPAVALPFIIRAAVVGGVATATEVSTIGIVYSALCGLLLYRRFDWRRLASMLIETAALS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
GAILLIIGAATGMAWALTQSGFSTALARFMTNLPGGAPMFLAVTIAAFIVLGSVLEGIPA
CHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVLFGPLLFPIAKQIGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAISRIHPDMGIRP
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCH
MLGYTLALLIGTIVIAAVPWFSIGLLH
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]