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The map label for this gene is siaP [H]

Identifier: 146338779

GI number: 146338779

Start: 1828428

End: 1829450

Strand: Direct

Name: siaP [H]

Synonym: BRADO1713

Alternate gene names: 146338779

Gene position: 1828428-1829450 (Clockwise)

Preceding gene: 146338778

Following gene: 146338780

Centisome position: 24.52

GC content: 62.76

Gene sequence:

>1023_bases
ATGCTCAAGGTCAGCCGTCGCGCGTTGTTGACCATTGCTGCCGGCGCCGCCGCCGCTGGCTATGTCTTGAAAACCCCCGC
CGTTCTGGCGCAGTCCGCGCCACTCAAGCTGAAATTCGGCAACGATCTGCCGGCCGCCCACTCGGTCAATGTGCGGCTGC
GCGAGGCGGTCGACACGATCACCGCGGAGACCAAGGGGCAGGTCGAGATCAGCCTGTTTCCGAACAATCAACTCGGCAGC
GACAGCGACATGATGACTCAGTTGCGCTCCGGCGCGCTCGAGCTCGCAACCATGCCGGGCACCGTGATGTCGACCTTGAT
CCCGACCGCATCGCTCACCGGCGTCGGCTTCGCCTTCACCAGCTACGACAAGGTGTGGGCGGCGATGGACGGCGAGGTCG
GCGGCTTCATCCGACGCAACATCGAGAAGGTCGGGCTGGTCCCCTTCGAGAGCGTCTGGGACAACGGCTTTCGGCAGATC
ACAACCAGCACCAAGCCGATCAACACGCCGGCCGATCTCGCCAACTTCAAGATCCGTGTGCCGGTCGTGCCGCTGTGGGT
CTCCATGTTCTCCGCCTTTGGCGCCTCGCCGATCAGCGTGCCCTTGAGTGAGGCCTATTCTGCACTGCAGACCAAGATCG
CCGATGGCCAGGAGAACCCGCTGGCATTGATCGAGTCGGCCAAGTTCTACGAGGTGCAGAAGTTCTGCTCGCTGACCAAT
CACAGCTGGGACGGCTTCTGGCTGCTGTCGAGCGGCAAGATCTGGAAGACGATCCCGCAGGACGTGCAGAAGCTGTTGCA
GACGACGTTCAATGCGGCCGCCAAGAAGCAACGCGCCGACATCGTCCAGGCCAATGCCGACCTGCAGAAGAGCCTGGAAG
GCAAGGGCCTGACCTTCAACAGGACCGATGCCGAGCTGTTCCAGGCGACGCTCGCCAAGACCAGCTTCTACAAGGACGCC
AAGGCCAAGTTCGGCGACGAGGCGTGGTCGCTGCTGCAGCGCTACGCTGGCAATATCAGCTGA

Upstream 100 bases:

>100_bases
ACGTTTTAGGTCCTCGAGAAAATCCACTTGCTTTGAATTCGAATTCCGAATACGAATTCATCAGAAGTCGCGAGAATGCG
ATCCATATGGGAGAGAGGCC

Downstream 100 bases:

>100_bases
CCTCAACCCCGGTTGCGGATGTCGGGCCATGACCATGCAGCTCGTTGACCACTCCAGTGCAGCCGTCCTTCCCGCAACCG
GGCACGCGTCCATCGCACGC

Product: putative TRAP-type C4-dicarboxylate transport system binding periplasmic protein DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLKVSRRALLTIAAGAAAAGYVLKTPAVLAQSAPLKLKFGNDLPAAHSVNVRLREAVDTITAETKGQVEISLFPNNQLGS
DSDMMTQLRSGALELATMPGTVMSTLIPTASLTGVGFAFTSYDKVWAAMDGEVGGFIRRNIEKVGLVPFESVWDNGFRQI
TTSTKPINTPADLANFKIRVPVVPLWVSMFSAFGASPISVPLSEAYSALQTKIADGQENPLALIESAKFYEVQKFCSLTN
HSWDGFWLLSSGKIWKTIPQDVQKLLQTTFNAAAKKQRADIVQANADLQKSLEGKGLTFNRTDAELFQATLAKTSFYKDA
KAKFGDEAWSLLQRYAGNIS

Sequences:

>Translated_340_residues
MLKVSRRALLTIAAGAAAAGYVLKTPAVLAQSAPLKLKFGNDLPAAHSVNVRLREAVDTITAETKGQVEISLFPNNQLGS
DSDMMTQLRSGALELATMPGTVMSTLIPTASLTGVGFAFTSYDKVWAAMDGEVGGFIRRNIEKVGLVPFESVWDNGFRQI
TTSTKPINTPADLANFKIRVPVVPLWVSMFSAFGASPISVPLSEAYSALQTKIADGQENPLALIESAKFYEVQKFCSLTN
HSWDGFWLLSSGKIWKTIPQDVQKLLQTTFNAAAKKQRADIVQANADLQKSLEGKGLTFNRTDAELFQATLAKTSFYKDA
KAKFGDEAWSLLQRYAGNIS
>Mature_340_residues
MLKVSRRALLTIAAGAAAAGYVLKTPAVLAQSAPLKLKFGNDLPAAHSVNVRLREAVDTITAETKGQVEISLFPNNQLGS
DSDMMTQLRSGALELATMPGTVMSTLIPTASLTGVGFAFTSYDKVWAAMDGEVGGFIRRNIEKVGLVPFESVWDNGFRQI
TTSTKPINTPADLANFKIRVPVVPLWVSMFSAFGASPISVPLSEAYSALQTKIADGQENPLALIESAKFYEVQKFCSLTN
HSWDGFWLLSSGKIWKTIPQDVQKLLQTTFNAAAKKQRADIVQANADLQKSLEGKGLTFNRTDAELFQATLAKTSFYKDA
KAKFGDEAWSLLQRYAGNIS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=281, Percent_Identity=32.0284697508897, Blast_Score=156, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36893; Mature: 36893

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVSRRALLTIAAGAAAAGYVLKTPAVLAQSAPLKLKFGNDLPAAHSVNVRLREAVDTI
CCCCCCHHEEEEECCHHHCCHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
TAETKGQVEISLFPNNQLGSDSDMMTQLRSGALELATMPGTVMSTLIPTASLTGVGFAFT
HCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHCCCHHCCCCEEHH
SYDKVWAAMDGEVGGFIRRNIEKVGLVPFESVWDNGFRQITTSTKPINTPADLANFKIRV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCHHHHCCEEEC
PVVPLWVSMFSAFGASPISVPLSEAYSALQTKIADGQENPLALIESAKFYEVQKFCSLTN
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHCC
HSWDGFWLLSSGKIWKTIPQDVQKLLQTTFNAAAKKQRADIVQANADLQKSLEGKGLTFN
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEC
RTDAELFQATLAKTSFYKDAKAKFGDEAWSLLQRYAGNIS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKVSRRALLTIAAGAAAAGYVLKTPAVLAQSAPLKLKFGNDLPAAHSVNVRLREAVDTI
CCCCCCHHEEEEECCHHHCCHHHCCHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
TAETKGQVEISLFPNNQLGSDSDMMTQLRSGALELATMPGTVMSTLIPTASLTGVGFAFT
HCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCHHHHHHHHCCCHHCCCCEEHH
SYDKVWAAMDGEVGGFIRRNIEKVGLVPFESVWDNGFRQITTSTKPINTPADLANFKIRV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCHHHHCCEEEC
PVVPLWVSMFSAFGASPISVPLSEAYSALQTKIADGQENPLALIESAKFYEVQKFCSLTN
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHCC
HSWDGFWLLSSGKIWKTIPQDVQKLLQTTFNAAAKKQRADIVQANADLQKSLEGKGLTFN
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEC
RTDAELFQATLAKTSFYKDAKAKFGDEAWSLLQRYAGNIS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA