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The map label for this gene is hypA

Identifier: 146338760

GI number: 146338760

Start: 1809727

End: 1810068

Strand: Direct

Name: hypA

Synonym: BRADO1694

Alternate gene names: 146338760

Gene position: 1809727-1810068 (Clockwise)

Preceding gene: 146338759

Following gene: 146338762

Centisome position: 24.27

GC content: 67.25

Gene sequence:

>342_bases
ATGCATGAGATGGCGCTGTGCGAGGGCATCGTCGAGATCGTCGAGGCCGAGGCGCGCAAGGGCGCGTTCTCCAAGGTGAA
GACGGTGTGGCTCGAAATCGGCGCGCTCAGCCATGTGGCGCCCGAGGCGCTGCGGTTCTGCTTCGAGGCGGTCACGGCGC
ATACGATCGCGCGCGGCGCGGCGCTGGAAATCATCGAGCAGAAGGGCTCGGCCTGGTGCCTCGGCTGCTCGCGCAGCGTC
GAGATCAGCCGGCGCTACGATGCCTGTTCCGAATGCGGCAGCCATCAGCTGCAGGTCACGGGCGGCGAGGACATGCGGGT
CAAGGAGCTGGAGGTCGAGTGA

Upstream 100 bases:

>100_bases
GCGCTGCTTCGCGATGGCAGGGATCGCGATGCCATTTCTGGCATGATCGGCTCGTTCGATCCCTGCGTCGGCGTCGGCCT
GACGGTCCGGGAGATGGCCG

Downstream 100 bases:

>100_bases
TGTGTACGGTGTGCGGCTGCGGCGACGGCCAATCCGCGATCGAGGCGGGTGATCATCATCACGATCACGGCGATCACGAT
CATCATCATGCGCATAGACA

Product: hydrogenase expression/formation protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGAALEIIEQKGSAWCLGCSRSV
EISRRYDACSECGSHQLQVTGGEDMRVKELEVE

Sequences:

>Translated_113_residues
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGAALEIIEQKGSAWCLGCSRSV
EISRRYDACSECGSHQLQVTGGEDMRVKELEVE
>Mature_113_residues
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGAALEIIEQKGSAWCLGCSRSV
EISRRYDACSECGSHQLQVTGGEDMRVKELEVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=43.3628318584071, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1789081, Length=114, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_BRASO (A4YNU5)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001203808.1
- STRING:   A4YNU5
- GeneID:   5119207
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO1694
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK820322
- BioCyc:   BSP376:BRADO1694-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12366; Mature: 12366

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALEIIEQKGSAWCLGCSRSVEISRRYDACSECGSHQLQVTGGEDMRVKELEVE
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MHEMALCEGIVEIVEAEARKGAFSKVKTVWLEIGALSHVAPEALRFCFEAVTAHTIARGA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ALEIIEQKGSAWCLGCSRSVEISRRYDACSECGSHQLQVTGGEDMRVKELEVE
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA