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The map label for this gene is hupD [H]

Identifier: 146338753

GI number: 146338753

Start: 1805497

End: 1806081

Strand: Direct

Name: hupD [H]

Synonym: BRADO1687

Alternate gene names: 146338753

Gene position: 1805497-1806081 (Clockwise)

Preceding gene: 146338752

Following gene: 146338754

Centisome position: 24.21

GC content: 65.13

Gene sequence:

>585_bases
ATGGCCGAGAAGAAGCTCGATCGCATCCTGGTGCTCGGGATCGGCAACATCCTGTGGGCGGACGAGGGGTTTGGCGTGCG
CGTGGTGGAGGAGTTCCACCGCCGCTATGCAGTTCCAGACAACGTCACCATTCTCGATGGCGGCACGCAGGGGCTGTATC
TCGTCAACTATGTCGAGGAGGCCGACGGCCTGATCGTTTTCGACGCCATCGACTACGGTCTCGCCCCGGGCGAGCTCAAG
CTCGTCCGTGACGAGGAGGTGCCGCGCTTCACCGGCGCGAAGAAGATGAGCCTGCACCAGACAGGCTTCCAGGAGGTGTT
AAGCGCGGCCGATCTGCTCGGCCGATATCCGCAGCGTCTCGCGCTGATCGGGTGCCAGCCGCTCGACCTCGAGGATTGGG
GCGGGCCGCTGACGGCGCCGGTGCGCGCGCAGATCGAGCCTGCCATCGAGCTAGCATGTGCTGTGCTGGCCGAGTGGGGC
GTCTCGGCGGTGTTGCGGCCCGAACCACTGGCCGGCGAGGCACGGCTGCTGACCAACGACATCGATCATCAAAGTTATGA
GATGCGCGCGGAACCGGCCGAATAG

Upstream 100 bases:

>100_bases
CGTCTACGCGGCCATCCGCGAAGACATCATGTCGCGCCAGAGCATCATCTCCTCGATGGTCTCGGGCGAGCGGCAGTTTC
GCGAGTAGGGGAGCCACGCG

Downstream 100 bases:

>100_bases
CTGGTTGCTGCGAGGGAGTTCACCATGTGCCTGGGCCTGCCGATGACGATCATGGCGACCGATGGCGTCTCGGCGCTGTG
CAGCTTCGACGGCGAGCAGC

Product: hydrogenase maturation protein hupD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAEKKLDRILVLGIGNILWADEGFGVRVVEEFHRRYAVPDNVTILDGGTQGLYLVNYVEEADGLIVFDAIDYGLAPGELK
LVRDEEVPRFTGAKKMSLHQTGFQEVLSAADLLGRYPQRLALIGCQPLDLEDWGGPLTAPVRAQIEPAIELACAVLAEWG
VSAVLRPEPLAGEARLLTNDIDHQSYEMRAEPAE

Sequences:

>Translated_194_residues
MAEKKLDRILVLGIGNILWADEGFGVRVVEEFHRRYAVPDNVTILDGGTQGLYLVNYVEEADGLIVFDAIDYGLAPGELK
LVRDEEVPRFTGAKKMSLHQTGFQEVLSAADLLGRYPQRLALIGCQPLDLEDWGGPLTAPVRAQIEPAIELACAVLAEWG
VSAVLRPEPLAGEARLLTNDIDHQSYEMRAEPAE
>Mature_193_residues
AEKKLDRILVLGIGNILWADEGFGVRVVEEFHRRYAVPDNVTILDGGTQGLYLVNYVEEADGLIVFDAIDYGLAPGELKL
VRDEEVPRFTGAKKMSLHQTGFQEVLSAADLLGRYPQRLALIGCQPLDLEDWGGPLTAPVRAQIEPAIELACAVLAEWGV
SAVLRPEPLAGEARLLTNDIDHQSYEMRAEPAE

Specific function: Not known. Could be involved in the processing of hydrogenase [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=181, Percent_Identity=49.7237569060773, Blast_Score=163, Evalue=6e-42,
Organism=Escherichia coli, GI1789367, Length=161, Percent_Identity=50.3105590062112, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 21324; Mature: 21192

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKLDRILVLGIGNILWADEGFGVRVVEEFHRRYAVPDNVTILDGGTQGLYLVNYVEE
CCCHHHCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEC
ADGLIVFDAIDYGLAPGELKLVRDEEVPRFTGAKKMSLHQTGFQEVLSAADLLGRYPQRL
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHE
ALIGCQPLDLEDWGGPLTAPVRAQIEPAIELACAVLAEWGVSAVLRPEPLAGEARLLTND
EEECCCCCCHHHCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECC
IDHQSYEMRAEPAE
CCCCCEECCCCCCC
>Mature Secondary Structure 
AEKKLDRILVLGIGNILWADEGFGVRVVEEFHRRYAVPDNVTILDGGTQGLYLVNYVEE
CCHHHCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEEC
ADGLIVFDAIDYGLAPGELKLVRDEEVPRFTGAKKMSLHQTGFQEVLSAADLLGRYPQRL
CCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHE
ALIGCQPLDLEDWGGPLTAPVRAQIEPAIELACAVLAEWGVSAVLRPEPLAGEARLLTND
EEECCCCCCHHHCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECC
IDHQSYEMRAEPAE
CCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8230232; 8163174; 12597275 [H]