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The map label for this gene is xpsE [H]

Identifier: 146338381

GI number: 146338381

Start: 1385256

End: 1386869

Strand: Direct

Name: xpsE [H]

Synonym: BRADO1293

Alternate gene names: 146338381

Gene position: 1385256-1386869 (Clockwise)

Preceding gene: 146338380

Following gene: 146338382

Centisome position: 18.58

GC content: 67.16

Gene sequence:

>1614_bases
ATGAGCTCGACTTCTCCTTTTCGACTGGCCGACGAAGACGGTGAGGTGAGATCGTCGCAGGGCGCCGATCCCGAATCTCC
CGACTTTGCCGACGCGATCGCGCGGCAGCTCGGCCTGCCGCGGATCGGGCTGGCCGGGTTGCTCGCGGCCAAGCCGCTGA
CCGAGCAGTTTTCGCGGCGCTTTCTCCGGGAGACGGCGGTCTTTCCGTTTCAATCGGCCGACCGTGAGCCGTGTCTCGCG
GTGGCAGATCCGCGCGATAGTGCGACGGCGCGCGCCGCGGAGCTCGTGTTCGGCGGACCGGTCGCGCTGGTGGTGGCCTC
TGCGGAGGATATCGGCACCGCGCTGAATCAGCTTGTTGGCGATGACGATGCGCCCGCCCGCAGCGAGACGGGTGAGCCGC
AGCTGCGCGAGGACGATATCGAGAGTCTGCGCGACCTTGCCACCGGCGCGCCGGTGGTGCGCGCCGTCAACGATCTGTTC
GAGCAGGCGGTGGAGCTGCGCGCCAGCGACATTCATGTCGAGGCGATGCGAAGCGGCTTGTCGATCCGGATGCGCGTGGA
CGGCCTGCTGAAGCCGGTCGCGGGGCCTTCGGGCGTGCTGCCCCGGGCCGTGATCTCGCGCATCAAGATCGTCGCCGGCC
TGAACATTGCGGAACGTCGGCTTCCTCAGGATGGCGCCGCGCGGCTGCGTGTCGGCCGCCACGAGCTGGACGTCCGTGTC
GCCGTGATGCCCACGCAGCATGGCGAATCGGCGGTGATCCGGCTGCTGCCGAAGGACCGCGGACTGCTGTCGATCGAGAA
GCTGGGCTTTGCTCCTCACGACGATCGAACGCTGCGCCGGCTGCTGGCGCTGCCGCATGGCATGATCGTGATCTGCGGGC
CGACAGGCAGCGGCAAGACCACCACGTTGGCGACCGCGCTGTCGATCCTCAACGAGCCGACACGCAAGATCCTCACCATC
GAGGATCCCGTGGAATACGAGATCCCCGGAATCAACCAGTCGCAGGTCAAGCCTGCCGTCGGGTTGACGTTCGCGTCCGC
GCTGCGATCCTTCGTGCGTCAGGACCCCGACGTCATCATGGTCGGCGAAGTTCGCGATAGTGAGACGGCTCACGTCGCGG
TCCATGCCGCGCTGACGGGTCACCTGGTGCTTACCACGCTGCACACCGAGAACGCGGCGGCGGCCGTGCCGCGGCTGCTC
GATCTCGGCGTCGAGGACTTCCTGCTGCGTTCGACGCTCCGGGCGGTGATCGCGCAGCGGCTGGTGCGCAAACTATGCGT
GCGGTGCAGGTCCTCTCATCTGTTGAGCGCCGACGATCTCTCCGCAGATCCGCGATATGCCGCGGTCGGCTTCGATGTCG
GCGAAACCGTCTACATGCCGGCGGGCTGCGAGAGCTGCGGCGGGACAGGCTATCGCGGCCGTCTCGGCATCTTCGAGGTC
CTGGAGCTCGACCAGGACATCCGGTCGCTGATCCAGGGTACGACTGACGCCGCAATGATCGATCGCAGCGCCATTCGCAA
CGGGATGACCACGATGCTCGATGATGGCGTTGCGAAATGCCGGGCCGGCGCGACGTCGGTCGCGGAAGTCTTGCGCGTCA
CGACGCTGCGGTGA

Upstream 100 bases:

>100_bases
AACGATCTTACAAGCGTCATCTTTGACTTCGAGAACGGGTGGCTCTCAGCCGTGCCCTCCGCGATGAGGTGATCGACAAC
CAATTGTCACGAGACGCGCC

Downstream 100 bases:

>100_bases
GCCGATGAGCACATTTCGATATCGTGCACTGACCGAGAGTGGCGACGTCGTGCATGGGACGATCTCGGCCGCGACAGCGA
AGGATGTCATCGACCGGATC

Product: putative general secretion pathway protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSSTSPFRLADEDGEVRSSQGADPESPDFADAIARQLGLPRIGLAGLLAAKPLTEQFSRRFLRETAVFPFQSADREPCLA
VADPRDSATARAAELVFGGPVALVVASAEDIGTALNQLVGDDDAPARSETGEPQLREDDIESLRDLATGAPVVRAVNDLF
EQAVELRASDIHVEAMRSGLSIRMRVDGLLKPVAGPSGVLPRAVISRIKIVAGLNIAERRLPQDGAARLRVGRHELDVRV
AVMPTQHGESAVIRLLPKDRGLLSIEKLGFAPHDDRTLRRLLALPHGMIVICGPTGSGKTTTLATALSILNEPTRKILTI
EDPVEYEIPGINQSQVKPAVGLTFASALRSFVRQDPDVIMVGEVRDSETAHVAVHAALTGHLVLTTLHTENAAAAVPRLL
DLGVEDFLLRSTLRAVIAQRLVRKLCVRCRSSHLLSADDLSADPRYAAVGFDVGETVYMPAGCESCGGTGYRGRLGIFEV
LELDQDIRSLIQGTTDAAMIDRSAIRNGMTTMLDDGVAKCRAGATSVAEVLRVTTLR

Sequences:

>Translated_537_residues
MSSTSPFRLADEDGEVRSSQGADPESPDFADAIARQLGLPRIGLAGLLAAKPLTEQFSRRFLRETAVFPFQSADREPCLA
VADPRDSATARAAELVFGGPVALVVASAEDIGTALNQLVGDDDAPARSETGEPQLREDDIESLRDLATGAPVVRAVNDLF
EQAVELRASDIHVEAMRSGLSIRMRVDGLLKPVAGPSGVLPRAVISRIKIVAGLNIAERRLPQDGAARLRVGRHELDVRV
AVMPTQHGESAVIRLLPKDRGLLSIEKLGFAPHDDRTLRRLLALPHGMIVICGPTGSGKTTTLATALSILNEPTRKILTI
EDPVEYEIPGINQSQVKPAVGLTFASALRSFVRQDPDVIMVGEVRDSETAHVAVHAALTGHLVLTTLHTENAAAAVPRLL
DLGVEDFLLRSTLRAVIAQRLVRKLCVRCRSSHLLSADDLSADPRYAAVGFDVGETVYMPAGCESCGGTGYRGRLGIFEV
LELDQDIRSLIQGTTDAAMIDRSAIRNGMTTMLDDGVAKCRAGATSVAEVLRVTTLR
>Mature_536_residues
SSTSPFRLADEDGEVRSSQGADPESPDFADAIARQLGLPRIGLAGLLAAKPLTEQFSRRFLRETAVFPFQSADREPCLAV
ADPRDSATARAAELVFGGPVALVVASAEDIGTALNQLVGDDDAPARSETGEPQLREDDIESLRDLATGAPVVRAVNDLFE
QAVELRASDIHVEAMRSGLSIRMRVDGLLKPVAGPSGVLPRAVISRIKIVAGLNIAERRLPQDGAARLRVGRHELDVRVA
VMPTQHGESAVIRLLPKDRGLLSIEKLGFAPHDDRTLRRLLALPHGMIVICGPTGSGKTTTLATALSILNEPTRKILTIE
DPVEYEIPGINQSQVKPAVGLTFASALRSFVRQDPDVIMVGEVRDSETAHVAVHAALTGHLVLTTLHTENAAAAVPRLLD
LGVEDFLLRSTLRAVIAQRLVRKLCVRCRSSHLLSADDLSADPRYAAVGFDVGETVYMPAGCESCGGTGYRGRLGIFEVL
ELDQDIRSLIQGTTDAAMIDRSAIRNGMTTMLDDGVAKCRAGATSVAEVLRVTTLR

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=432, Percent_Identity=44.9074074074074, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1786296, Length=379, Percent_Identity=41.1609498680739, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI87082188, Length=195, Percent_Identity=45.1282051282051, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 57485; Mature: 57353

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTSPFRLADEDGEVRSSQGADPESPDFADAIARQLGLPRIGLAGLLAAKPLTEQFSRR
CCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHH
FLRETAVFPFQSADREPCLAVADPRDSATARAAELVFGGPVALVVASAEDIGTALNQLVG
HHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHEECCCEEEEEECHHHHHHHHHHHHC
DDDAPARSETGEPQLREDDIESLRDLATGAPVVRAVNDLFEQAVELRASDIHVEAMRSGL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHCCC
SIRMRVDGLLKPVAGPSGVLPRAVISRIKIVAGLNIAERRLPQDGAARLRVGRHELDVRV
EEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHCCCCEEEEEEE
AVMPTQHGESAVIRLLPKDRGLLSIEKLGFAPHDDRTLRRLLALPHGMIVICGPTGSGKT
EEEECCCCCCEEEEEECCCCCEEEHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCH
TTLATALSILNEPTRKILTIEDPVEYEIPGINQSQVKPAVGLTFASALRSFVRQDPDVIM
HHHHHHHHHHCCCCCEEEEECCCCCEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEE
VGEVRDSETAHVAVHAALTGHLVLTTLHTENAAAAVPRLLDLGVEDFLLRSTLRAVIAQR
EECCCCCCCEEEEEEEEEECEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVRKLCVRCRSSHLLSADDLSADPRYAAVGFDVGETVYMPAGCESCGGTGYRGRLGIFEV
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHH
LELDQDIRSLIQGTTDAAMIDRSAIRNGMTTMLDDGVAKCRAGATSVAEVLRVTTLR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSTSPFRLADEDGEVRSSQGADPESPDFADAIARQLGLPRIGLAGLLAAKPLTEQFSRR
CCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHH
FLRETAVFPFQSADREPCLAVADPRDSATARAAELVFGGPVALVVASAEDIGTALNQLVG
HHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHEECCCEEEEEECHHHHHHHHHHHHC
DDDAPARSETGEPQLREDDIESLRDLATGAPVVRAVNDLFEQAVELRASDIHVEAMRSGL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHCCC
SIRMRVDGLLKPVAGPSGVLPRAVISRIKIVAGLNIAERRLPQDGAARLRVGRHELDVRV
EEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHCCCCEEEEEEE
AVMPTQHGESAVIRLLPKDRGLLSIEKLGFAPHDDRTLRRLLALPHGMIVICGPTGSGKT
EEEECCCCCCEEEEEECCCCCEEEHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCH
TTLATALSILNEPTRKILTIEDPVEYEIPGINQSQVKPAVGLTFASALRSFVRQDPDVIM
HHHHHHHHHHCCCCCEEEEECCCCCEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEE
VGEVRDSETAHVAVHAALTGHLVLTTLHTENAAAAVPRLLDLGVEDFLLRSTLRAVIAQR
EECCCCCCCEEEEEEEEEECEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LVRKLCVRCRSSHLLSADDLSADPRYAAVGFDVGETVYMPAGCESCGGTGYRGRLGIFEV
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHH
LELDQDIRSLIQGTTDAAMIDRSAIRNGMTTMLDDGVAKCRAGATSVAEVLRVTTLR
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]