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The map label for this gene is glpD [H]

Identifier: 146338309

GI number: 146338309

Start: 1289019

End: 1290569

Strand: Direct

Name: glpD [H]

Synonym: BRADO1214

Alternate gene names: 146338309

Gene position: 1289019-1290569 (Clockwise)

Preceding gene: 146338308

Following gene: 146338310

Centisome position: 17.29

GC content: 68.67

Gene sequence:

>1551_bases
ATGGCGGACTACGATCTCGCGATCATAGGTGGCGGTCTCAACGGCGTCAGCCTCGCGCGCGACGCGGCGGGTCGAGGTTT
GCGCGTGCTCCTGGTCGAGCAGGGCGATCTCGGCGGTGCTGCATCGTCGGCGACATCGCGACTCGTGCATGGCGACCTCG
CCGCGCTGGAGCGGCGGAGCCTGTTGCGCGTGCGCAGGTCGCTCGCCGAGCGCGACGTGTGGCTGACGATCGCCCCGCAT
GTGGTGCGCCCGGTTCGCTTTGCGATTCCGGCTCATTCCAATGAGCGTCCGCACTGGCAGTTGCGGACCGGACTTTGGCT
CTATGACCGGCTCGCGGCACGTCGGCGGTTGCCCGCGGCGTCGACGCTGGATGTGACGCATCATCCGATCGGCGACGCGC
TGAAGCGCCCGATCGGGACGGCTTTCGAATATTCGGACTGCGTGGTCGACGATTCCCGGCTGGTGGCGCTGACGGCGCTG
GATGCCGCCGAACGTGGCGCCGCCATCCGGACCGGCGCCCGCTGCATCCGCGCCGACCGCGACCGCCTCTGGCGTCTGGC
GATCATCGACCGTGGCCATCGCCGCATCGTCACGGCTGGCGCGCTCGCCAATGCCGCGGGTGCCTGGAGCGTCTCGACCG
CGGAGACGGTGCTGCGCCAGCCGCCGCTGCGCGCCACGGCAAGGCAGATCAACCAGATCGTGGTGCCCCGCCTGTTCGAT
GTGGACGCCGTCTACGTGTTCCAGAATTCGGACGGGCGGCTGATCTTCGCCCAACCCTATGCCGGCGCGTTCACTCTGAT
CGGCACGGTGGCTCACGGCTTCACGGGCGATCCTGCCGTGGTGACGGTGCCGGCGGCGGATGTGAGCTATCTCTGCAAGG
CGGCCAATCGTTACTTCCGCTCCGACATTCAGCCCGCCGATGTCTTGAGAACCGTTTCCGGCGCCAACATGATGCTGCTG
CGCGGGGAAAAGGCTGGGCAGCCTGAGGCCGTGGTGAGCTTCGATGCCAGCCGCAGCAAAGCGCCGCTCCTGACCATGTG
CGGTGGCGATGTGACGACCGTCCGACGTCGCGCCGAGCAGGCCGTTTCAAGGCTTGCCAGGTTTTTTCCGATGACGCCGC
GCTGGACGGCCGGGATGGCGTTGCCGGGAGGCAATTTCGATTGGCAGCATTTTGAGGACCTCGTCGACGAGGCAGGGGAT
CGCTGGCGCTTTCTTGGCGAGGCAGAGGCACGCCGCATGGTCGGCGCCTACGGCACCCGCCTGAGCGAGATCCTCGGCGA
AGCCCGGAGCCGGTCGGATCTCGGCCAGGCTTTCGGCGCGCAGCTGACGGAGGCCGAGGTCCGCTATCTCATGACCAAGG
AATGGGCGCGGTTTCCCGAGGACGTGCTGTGGCGCCGGACCAAGCTCGGCCTCAGCCTCTCGGCAGCCGAGCGCGATGCG
CTGGCTGCCTTCATGGCGCAGGCGGGCGCCTCTGGGAGCGCCGCCCCCCGGCGCGACGGGGACGGGGATAGTCCGGCCCG
CGCGGTTGAGCTGCAGTCGATCGGCGGCTAG

Upstream 100 bases:

>100_bases
CAGCGCGGATTTATCCGCGGTCCTGTTTGCTCCGCCACTACGAGAATCATCGGCTGGGGTCTACGATCGTACGTGCTGGC
ACGCTCGAAGATTTTGGCGC

Downstream 100 bases:

>100_bases
CTTGCCCTCGCCGCGCCGTTCGGGCCGGCGGGGTGAATTGACCGGGATCATGGCCGACCACATCGCGACTTCAGAGCCCG
CCGCGGAGCCGGCGCTACCA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MADYDLAIIGGGLNGVSLARDAAGRGLRVLLVEQGDLGGAASSATSRLVHGDLAALERRSLLRVRRSLAERDVWLTIAPH
VVRPVRFAIPAHSNERPHWQLRTGLWLYDRLAARRRLPAASTLDVTHHPIGDALKRPIGTAFEYSDCVVDDSRLVALTAL
DAAERGAAIRTGARCIRADRDRLWRLAIIDRGHRRIVTAGALANAAGAWSVSTAETVLRQPPLRATARQINQIVVPRLFD
VDAVYVFQNSDGRLIFAQPYAGAFTLIGTVAHGFTGDPAVVTVPAADVSYLCKAANRYFRSDIQPADVLRTVSGANMMLL
RGEKAGQPEAVVSFDASRSKAPLLTMCGGDVTTVRRRAEQAVSRLARFFPMTPRWTAGMALPGGNFDWQHFEDLVDEAGD
RWRFLGEAEARRMVGAYGTRLSEILGEARSRSDLGQAFGAQLTEAEVRYLMTKEWARFPEDVLWRRTKLGLSLSAAERDA
LAAFMAQAGASGSAAPRRDGDGDSPARAVELQSIGG

Sequences:

>Translated_516_residues
MADYDLAIIGGGLNGVSLARDAAGRGLRVLLVEQGDLGGAASSATSRLVHGDLAALERRSLLRVRRSLAERDVWLTIAPH
VVRPVRFAIPAHSNERPHWQLRTGLWLYDRLAARRRLPAASTLDVTHHPIGDALKRPIGTAFEYSDCVVDDSRLVALTAL
DAAERGAAIRTGARCIRADRDRLWRLAIIDRGHRRIVTAGALANAAGAWSVSTAETVLRQPPLRATARQINQIVVPRLFD
VDAVYVFQNSDGRLIFAQPYAGAFTLIGTVAHGFTGDPAVVTVPAADVSYLCKAANRYFRSDIQPADVLRTVSGANMMLL
RGEKAGQPEAVVSFDASRSKAPLLTMCGGDVTTVRRRAEQAVSRLARFFPMTPRWTAGMALPGGNFDWQHFEDLVDEAGD
RWRFLGEAEARRMVGAYGTRLSEILGEARSRSDLGQAFGAQLTEAEVRYLMTKEWARFPEDVLWRRTKLGLSLSAAERDA
LAAFMAQAGASGSAAPRRDGDGDSPARAVELQSIGG
>Mature_515_residues
ADYDLAIIGGGLNGVSLARDAAGRGLRVLLVEQGDLGGAASSATSRLVHGDLAALERRSLLRVRRSLAERDVWLTIAPHV
VRPVRFAIPAHSNERPHWQLRTGLWLYDRLAARRRLPAASTLDVTHHPIGDALKRPIGTAFEYSDCVVDDSRLVALTALD
AAERGAAIRTGARCIRADRDRLWRLAIIDRGHRRIVTAGALANAAGAWSVSTAETVLRQPPLRATARQINQIVVPRLFDV
DAVYVFQNSDGRLIFAQPYAGAFTLIGTVAHGFTGDPAVVTVPAADVSYLCKAANRYFRSDIQPADVLRTVSGANMMLLR
GEKAGQPEAVVSFDASRSKAPLLTMCGGDVTTVRRRAEQAVSRLARFFPMTPRWTAGMALPGGNFDWQHFEDLVDEAGDR
WRFLGEAEARRMVGAYGTRLSEILGEARSRSDLGQAFGAQLTEAEVRYLMTKEWARFPEDVLWRRTKLGLSLSAAERDAL
AAFMAQAGASGSAAPRRDGDGDSPARAVELQSIGG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=531, Percent_Identity=27.1186440677966, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI285002231, Length=531, Percent_Identity=27.1186440677966, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI2367226, Length=497, Percent_Identity=36.4185110663984, Blast_Score=277, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI115534726, Length=524, Percent_Identity=26.9083969465649, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17509253, Length=531, Percent_Identity=25.8003766478343, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322036, Length=558, Percent_Identity=26.3440860215054, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586295, Length=513, Percent_Identity=26.1208576998051, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI161077125, Length=537, Percent_Identity=25.1396648044693, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653942, Length=537, Percent_Identity=25.1396648044693, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653944, Length=537, Percent_Identity=25.1396648044693, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20130025, Length=537, Percent_Identity=25.1396648044693, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56024; Mature: 55893

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYDLAIIGGGLNGVSLARDAAGRGLRVLLVEQGDLGGAASSATSRLVHGDLAALERRS
CCCCEEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LLRVRRSLAERDVWLTIAPHVVRPVRFAIPAHSNERPHWQLRTGLWLYDRLAARRRLPAA
HHHHHHHHHHCCEEEEECHHHHCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCC
STLDVTHHPIGDALKRPIGTAFEYSDCVVDDSRLVALTALDAAERGAAIRTGARCIRADR
CCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHCCH
DRLWRLAIIDRGHRRIVTAGALANAAGAWSVSTAETVLRQPPLRATARQINQIVVPRLFD
HHEEEEEEEECCCCEEEEECHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCEEEC
VDAVYVFQNSDGRLIFAQPYAGAFTLIGTVAHGFTGDPAVVTVPAADVSYLCKAANRYFR
CCEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
SDIQPADVLRTVSGANMMLLRGEKAGQPEAVVSFDASRSKAPLLTMCGGDVTTVRRRAEQ
CCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHHH
AVSRLARFFPMTPRWTAGMALPGGNFDWQHFEDLVDEAGDRWRFLGEAEARRMVGAYGTR
HHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHH
LSEILGEARSRSDLGQAFGAQLTEAEVRYLMTKEWARFPEDVLWRRTKLGLSLSAAERDA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECHHHHHH
LAAFMAQAGASGSAAPRRDGDGDSPARAVELQSIGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
ADYDLAIIGGGLNGVSLARDAAGRGLRVLLVEQGDLGGAASSATSRLVHGDLAALERRS
CCCEEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
LLRVRRSLAERDVWLTIAPHVVRPVRFAIPAHSNERPHWQLRTGLWLYDRLAARRRLPAA
HHHHHHHHHHCCEEEEECHHHHCCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCC
STLDVTHHPIGDALKRPIGTAFEYSDCVVDDSRLVALTALDAAERGAAIRTGARCIRADR
CCCCCCCCCCHHHHHCCCCCCCCCCCEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHCCH
DRLWRLAIIDRGHRRIVTAGALANAAGAWSVSTAETVLRQPPLRATARQINQIVVPRLFD
HHEEEEEEEECCCCEEEEECHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCEEEC
VDAVYVFQNSDGRLIFAQPYAGAFTLIGTVAHGFTGDPAVVTVPAADVSYLCKAANRYFR
CCEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
SDIQPADVLRTVSGANMMLLRGEKAGQPEAVVSFDASRSKAPLLTMCGGDVTTVRRRAEQ
CCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHHH
AVSRLARFFPMTPRWTAGMALPGGNFDWQHFEDLVDEAGDRWRFLGEAEARRMVGAYGTR
HHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHH
LSEILGEARSRSDLGQAFGAQLTEAEVRYLMTKEWARFPEDVLWRRTKLGLSLSAAERDA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECHHHHHH
LAAFMAQAGASGSAAPRRDGDGDSPARAVELQSIGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]