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The map label for this gene is yegE [H]

Identifier: 146338303

GI number: 146338303

Start: 1282749

End: 1283243

Strand: Direct

Name: yegE [H]

Synonym: BRADO1207

Alternate gene names: 146338303

Gene position: 1282749-1283243 (Clockwise)

Preceding gene: 146338299

Following gene: 146338306

Centisome position: 17.2

GC content: 66.67

Gene sequence:

>495_bases
TTGACCGCCACGGCTGAGCGCGATTTCCTGCTCGACATCTTCAACCGGCGTGGCTTTGCCCGCGAGCTGCACCGCTCGAT
CGCGTTCATCAAACGCTACGATGCCACCGGCGCGCTGGTCGTGCTCGATGTCGATCGGCTGAAGCCGATCAACGATACGT
TCGGCCATGCCGCCGGCGACGAGGTCCTCAAGGCCGTGGCGCGCGTCCTCAGTGAGGAGGTTCGTTCCTCCGACGTCATC
GGGCGGCTCGGCGGCGACGAGTTCGGCGTGCTGCTATGGCATCTCAGCGAGACCGACGCGCGCATCAAGGCGGCGGCGCT
GGAGGAGGCCATCGACATGTTGAGCTTCACTTTCGGCGACCAGACGGTCAGGGCAGGCGCATCGGCGGGCGTGGCCTTGC
TGGACAAGCGCGTCAATCCGGTGCGCGCGCTCGAGGAGGCCGATCGCGCGATGTACATCCGCAAGGCGCAGCGCAGGCGC
GAGAGCCGTGGTTGA

Upstream 100 bases:

>100_bases
CGGGCGGGCGCCGAAATCGGAGGCGGTCCCCCCAGGCGCGCGACAGACGATCCGGCGTCTCAAGGCCGAGCTGGCAGCAG
CCCGGCTCCGGATCGAGGAG

Downstream 100 bases:

>100_bases
TCGAGGCAGCGGTAATCGTAACCATTGTTCAAGGGCAGCTGACGCTGTGCGGTCGCCTTGCTGCCCACGTCGCGCCGCGG
TCGGCGAGTCATAACTCGCC

Product: putative diguanylate cyclase

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTATAERDFLLDIFNRRGFARELHRSIAFIKRYDATGALVVLDVDRLKPINDTFGHAAGDEVLKAVARVLSEEVRSSDVI
GRLGGDEFGVLLWHLSETDARIKAAALEEAIDMLSFTFGDQTVRAGASAGVALLDKRVNPVRALEEADRAMYIRKAQRRR
ESRG

Sequences:

>Translated_164_residues
MTATAERDFLLDIFNRRGFARELHRSIAFIKRYDATGALVVLDVDRLKPINDTFGHAAGDEVLKAVARVLSEEVRSSDVI
GRLGGDEFGVLLWHLSETDARIKAAALEEAIDMLSFTFGDQTVRAGASAGVALLDKRVNPVRALEEADRAMYIRKAQRRR
ESRG
>Mature_163_residues
TATAERDFLLDIFNRRGFARELHRSIAFIKRYDATGALVVLDVDRLKPINDTFGHAAGDEVLKAVARVLSEEVRSSDVIG
RLGGDEFGVLLWHLSETDARIKAAALEEAIDMLSFTFGDQTVRAGASAGVALLDKRVNPVRALEEADRAMYIRKAQRRRE
SRG

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=156, Percent_Identity=36.5384615384615, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786584, Length=166, Percent_Identity=36.144578313253, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=33.1210191082803, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=33.1210191082803, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=29.5180722891566, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=35.2201257861635, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=28.3870967741935, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=34.7305389221557, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI87081977, Length=165, Percent_Identity=32.1212121212121, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87081881, Length=92, Percent_Identity=39.1304347826087, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1787816, Length=118, Percent_Identity=32.2033898305085, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788085, Length=157, Percent_Identity=28.0254777070064, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 18201; Mature: 18070

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATAERDFLLDIFNRRGFARELHRSIAFIKRYDATGALVVLDVDRLKPINDTFGHAAGD
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHCCCCCHH
EVLKAVARVLSEEVRSSDVIGRLGGDEFGVLLWHLSETDARIKAAALEEAIDMLSFTFGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
QTVRAGASAGVALLDKRVNPVRALEEADRAMYIRKAQRRRESRG
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATAERDFLLDIFNRRGFARELHRSIAFIKRYDATGALVVLDVDRLKPINDTFGHAAGD
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHCCCCCHH
EVLKAVARVLSEEVRSSDVIGRLGGDEFGVLLWHLSETDARIKAAALEEAIDMLSFTFGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
QTVRAGASAGVALLDKRVNPVRALEEADRAMYIRKAQRRRESRG
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]