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The map label for this gene is metH [H]

Identifier: 146338098

GI number: 146338098

Start: 1056411

End: 1060265

Strand: Reverse

Name: metH [H]

Synonym: BRADO0994

Alternate gene names: 146338098

Gene position: 1060265-1056411 (Counterclockwise)

Preceding gene: 146338099

Following gene: 146338097

Centisome position: 14.22

GC content: 66.43

Gene sequence:

>3855_bases
ATGTCCTCCCCTGTGTCCACCGCGCGGTCCGCTTTCCTCGCTGCAGCAGCCAAGCGCATCCTGATCCTCGACGGTGCCAT
GGGCACGATGATCCAGGCGTTGCAGTTCGACGAGGCGGCGTTCCGCAGCGAGCGTTTCAAGGACTTTCATCGTGACCTGC
GCGGCAACAATGACCTCCTGATCCTTACGCAGCCGGACGCGATCGAGGACATTCACGCGCAGTATCTGCGCGCTGGCGCC
GACATCGTCGCCACCAATACGTTCTCGGCGACATCGATCGCGCAGGCCGATTACGACCTCTCCGACATCATCTACGAGCT
CAACCGCGAGGGCGCGCGGCTGGCCCGCAATGCCGCCACGCGCGTCGCGGCCGAGGACGGCAAGCCGCGTTTCGTCGCCG
GTGCGATGGGCCCGACCAACCGCACCGCGTCGATCTCGCCCGACGTCTCCAACCCCGGCTATCGCGCCGTCACCTTCGAC
GATCTGCGCCTCGCCTATGGCGAGCAGGCGCGTGGGCTGCTCGACGGCGGGGCCGACATCCTGCTGGTCGAAACCATCTT
CGACACGCTCAACGCCAAGGCCGCGCTGTATGCGATCGCCGAGCTCTGCGAGGCGCGCGGCATCGACGTGCCCGTGATGA
TCTCCGGCACCATCACCGACAAGTCCGGCCGCCTGCTCTCGGGCCAGATGCCGGAGGCGTTCTGGAATTCGGTGCGTCAC
GCCAAGCCGCTGACGATCGGCTTCAATTGCGCGCTCGGCGCCGAGGACCTGCGCGCCCATGTCGCCGACATCGGCCGCGT
CGCCGACACGCTGGTCTGCGCCTATCCCAATGCCGGCCTGCCCAACGAGTTCGGCCAGTATGACGAGACGCCGGCCTACA
TGGCGCGGCTGATCGGCGAGTTCGCGCGTGACGGCCTCGTCAACATCGTCGGCGGCTGCTGCGGCACCACGCCGGATCAT
ATCGCGGCGATCGCCGCCGCCGTCGCTCCGCACAAGCCGCGCATCGTGCTTGACATCGCGCCGCGGCTGCGGCTGTCGGG
CCTGGAGCCGTTCGAGCTGACGCCGGAAATTCCGTTCGTCAATGTCGGCGAGCGCACCAACGTCACCGGCTCGGCCAAAT
TCCGCAAGCTGATCACCGCGGGCGACTACACGGCCGCGCTGCAGGTCGCGCGCGACCAGGTCGAGAACGGCGCGCAGGTC
ATCGACGTCAACATGGACGAGGGCCTCCTGGATTCGGAAGCCGCGATGCGGACCTTCCTCAACCTCGTCGCCGCCGAGCC
TGACATCGCCCGCGTCCCTGTCATGGTCGACTCCTCGAAATTCCACGTTATCGAGGCCGGCCTGAAATGCGTGCAGGGTA
AGCCTGTCGTGAACTCGATTTCGCTGAAGGAAGGCGAGGAGAAGTTCATCCACGAGGCGCAGATCGCGCGCCGCCATGGC
GCCGCGGTCGTCGTGATGGCGTTCGACGAGACCGGCCAGGCCGACACCTACCAGCGCAAGACCGAGATCTGCGCCCGCGC
CTACAAGATCCTGGTCGAGACGGTCGGCTTCCCGCCGGAAGACATCATTTTCGATCCCAACATCTTTGCGATCGCGACAG
GGATCGAGGAGCACGACAATTACGGCGTCGACTTCATCGAAGCGACGCGCTGGATCCGCCAGAACCTGCCGCATGCGCAT
GTTTCGGGCGGCGTCTCCAATCTGTCGTTCTCGTTCCGCGGTAATGAGCCGGTGCGCGAGGCGATGCATTCGGTGTTCCT
GTATCACGCCATCAAGGCGGGCATGGACATGGGCATCGTCAATGCCGGGCAGATGATCGTCTATGACGACATCGATCCGG
AGCTGCGCCAGGTCTGCGAGGACGTCGTGCTCAACCGCGACCCCGGCGCGTCCGAGCGGCTGCTGGCGCTGGCCGAGAAG
TTCCGCGGCCAGGGCAAGCAGACCAAGGAGGCCGACCTGGCCTGGCGCGAATGGCCGGTGGAAAAGCGGCTGTCGCACGC
GCTGGTGCACGGGATCACCGAGTTCATCGATGTTGACACCGAGGAGGCGCGCGCCAAGTCGACGCGGCCGCTCGACGTCA
TCGAAGGCCCGCTGATGGCCGGCATGAACGTCGTCGGCGACCTGTTCGGCGACGGCAAGATGTTCCTGCCGCAGGTCGTG
AAGTCGGCGCGCGTGATGAAGCAGGCGGTCGCCTATCTGATGCCATTCATGGAGGCCGAGAAGGCCGCCAACAAGGGCCG
CGCCAACGAGCGCTCCAATGCCGGCAAGATCGTGCTCGCCACCGTCAAGGGCGACGTCCACGACATCGGCAAGAACATTG
TCGGCATCGTGCTCCAGTGCAACAATTTCGAGGTCATCGACCTCGGCGTCATGGTGCCCGCCGCCAAGATCATCGACACC
GCAAAGGCGGAGAATGCCGACATCATCGGCCTCTCCGGCCTGATCACGCCGTCGCTCGACGAGATGGCCTATCTGGCGTC
CGAGATGGAACGTCAGGGCCTGAATGTACCCTTGCTGATCGGCGGCGCCACGACGAGCCGCGTCCACACCGCCGTCAAGA
TCGACCCGAACTACCAGGGCGGTCCGGTGGTGCATGTCAACGACGCCAGCCGCGCCGTCGGCGTCGCCTCCTCGCTGCTG
TCGCCCGAGCGCAAGGACGCCTATGCGGCTGACATCCGCACCGAGTATCAGAAGATCGCCGCCGCGCATCTGCGCGGCCA
GGCCGACAAGAAGCGGCTGTCGCTGGCTGACGCGCGCGCCAACGCGCCGAAGATCGACTTCGCCAACGCCAGGCCGGTAA
AGCCGACCTTTCTGGGCACCAAGACCTTCGTCGACTACGACCTCGCCGAGCTCGTGCCCTATATCGACTGGACGCCGTTC
TTCCAGACCTGGGAGCTCGCGGGCCGCTTCCCTGCGATTCTCGACGACGCCAAGGTCGGCGAGGCCGCGCGGGCGCTGTA
TGACGATGCCCAGAAGATGCTGAAGCAGATCGTCGACGAGAAGTGGTTCACGGCGCGCGCCGCGATCGGCTTCTGGCCGG
CCAACGCCGTCGGCGACGACATCGTGCTCTATGCCGATGACAGCCGCACCAAGACCGTGGCGACGATGCACACACTGCGC
CAGCAGCTCGAGAAGCGCGAAGGCCGCTTCAACACCGCGCTGTCCGATTTCGTCGCGCCGATGGATTCCGGCGTGCCGGA
CTATGTCGGCGGCTTCGTCGTCACCACGGGGCTTGGCGAGGATGCGGTGGCCGACCGCTTCAAGAACGCCAATGACGACT
ACTCCTCGATCCTGGTGAAAGCGCTGGCCGACCGCCTCGCCGAGGCGTTTGCCGAGCGCCTGCACGCCCGCGTGCGCCGC
GAGTTCTGGGCTTATGCGCCGGATGAGGCGCTCTCGGCCGATGATTTGATCCTGGAGAAGTACCAGGGCATCCGCCCCGC
CCCCGGCTATCCGGCGCAGCCGGATCACACCGAGAAGGCGACGTTGTTCAAACTGCTCGATGCGGAGACAAGTGCCGGCG
TGCGGCTGACGGAGAGCTTTGCGATGTGGCCGGGCTCGTCGGTCTCGGGTCTCTACTTCGCCTCGCCTGAGAGCTTCTAT
TTCGGCGTCGGCAAGATCGAGCGCGACCAGGTCGAGGACTACGCCGCGCGCAAGGGCATGACGGTGGCCGAGGTCGAGCG
CTGGCTGGCGCCGATCCTGAACTACATCCCGGCGCGGGGCGGCCAGGCGGCGCAGACGCCGCGCGCGGCCGCGACGCTCG
CCCCGGCCAACGACGCCGAACTCGCCAGCCACCCGCCGGGCTGCGCCTGCGCGGTGCACCTCGCCTGGCGCAAGAAGGCC
GTCGGCGCGAAGTAG

Upstream 100 bases:

>100_bases
ACACCTTCCATTTCTACACCATGAACCGCGCCGACCTCGTGTTCGCGATCAGCCATCTGCTTGGCATCCGTCCGAAGTCC
GTCAACAAGGTCGCCGCCTG

Downstream 100 bases:

>100_bases
GTGGCACTGCCTCCAAACCCCCACGGCTGTCGTCCCTGCGAACGCAGGGACCCATACCGCGTGATCTCTCCCTCGTCCGC
GGTGGCTGAAACCGAGCAAA

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1284; Mature: 1283

Protein sequence:

>1284_residues
MSSPVSTARSAFLAAAAKRILILDGAMGTMIQALQFDEAAFRSERFKDFHRDLRGNNDLLILTQPDAIEDIHAQYLRAGA
DIVATNTFSATSIAQADYDLSDIIYELNREGARLARNAATRVAAEDGKPRFVAGAMGPTNRTASISPDVSNPGYRAVTFD
DLRLAYGEQARGLLDGGADILLVETIFDTLNAKAALYAIAELCEARGIDVPVMISGTITDKSGRLLSGQMPEAFWNSVRH
AKPLTIGFNCALGAEDLRAHVADIGRVADTLVCAYPNAGLPNEFGQYDETPAYMARLIGEFARDGLVNIVGGCCGTTPDH
IAAIAAAVAPHKPRIVLDIAPRLRLSGLEPFELTPEIPFVNVGERTNVTGSAKFRKLITAGDYTAALQVARDQVENGAQV
IDVNMDEGLLDSEAAMRTFLNLVAAEPDIARVPVMVDSSKFHVIEAGLKCVQGKPVVNSISLKEGEEKFIHEAQIARRHG
AAVVVMAFDETGQADTYQRKTEICARAYKILVETVGFPPEDIIFDPNIFAIATGIEEHDNYGVDFIEATRWIRQNLPHAH
VSGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPELRQVCEDVVLNRDPGASERLLALAEK
FRGQGKQTKEADLAWREWPVEKRLSHALVHGITEFIDVDTEEARAKSTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVV
KSARVMKQAVAYLMPFMEAEKAANKGRANERSNAGKIVLATVKGDVHDIGKNIVGIVLQCNNFEVIDLGVMVPAAKIIDT
AKAENADIIGLSGLITPSLDEMAYLASEMERQGLNVPLLIGGATTSRVHTAVKIDPNYQGGPVVHVNDASRAVGVASSLL
SPERKDAYAADIRTEYQKIAAAHLRGQADKKRLSLADARANAPKIDFANARPVKPTFLGTKTFVDYDLAELVPYIDWTPF
FQTWELAGRFPAILDDAKVGEAARALYDDAQKMLKQIVDEKWFTARAAIGFWPANAVGDDIVLYADDSRTKTVATMHTLR
QQLEKREGRFNTALSDFVAPMDSGVPDYVGGFVVTTGLGEDAVADRFKNANDDYSSILVKALADRLAEAFAERLHARVRR
EFWAYAPDEALSADDLILEKYQGIRPAPGYPAQPDHTEKATLFKLLDAETSAGVRLTESFAMWPGSSVSGLYFASPESFY
FGVGKIERDQVEDYAARKGMTVAEVERWLAPILNYIPARGGQAAQTPRAAATLAPANDAELASHPPGCACAVHLAWRKKA
VGAK

Sequences:

>Translated_1284_residues
MSSPVSTARSAFLAAAAKRILILDGAMGTMIQALQFDEAAFRSERFKDFHRDLRGNNDLLILTQPDAIEDIHAQYLRAGA
DIVATNTFSATSIAQADYDLSDIIYELNREGARLARNAATRVAAEDGKPRFVAGAMGPTNRTASISPDVSNPGYRAVTFD
DLRLAYGEQARGLLDGGADILLVETIFDTLNAKAALYAIAELCEARGIDVPVMISGTITDKSGRLLSGQMPEAFWNSVRH
AKPLTIGFNCALGAEDLRAHVADIGRVADTLVCAYPNAGLPNEFGQYDETPAYMARLIGEFARDGLVNIVGGCCGTTPDH
IAAIAAAVAPHKPRIVLDIAPRLRLSGLEPFELTPEIPFVNVGERTNVTGSAKFRKLITAGDYTAALQVARDQVENGAQV
IDVNMDEGLLDSEAAMRTFLNLVAAEPDIARVPVMVDSSKFHVIEAGLKCVQGKPVVNSISLKEGEEKFIHEAQIARRHG
AAVVVMAFDETGQADTYQRKTEICARAYKILVETVGFPPEDIIFDPNIFAIATGIEEHDNYGVDFIEATRWIRQNLPHAH
VSGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPELRQVCEDVVLNRDPGASERLLALAEK
FRGQGKQTKEADLAWREWPVEKRLSHALVHGITEFIDVDTEEARAKSTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVV
KSARVMKQAVAYLMPFMEAEKAANKGRANERSNAGKIVLATVKGDVHDIGKNIVGIVLQCNNFEVIDLGVMVPAAKIIDT
AKAENADIIGLSGLITPSLDEMAYLASEMERQGLNVPLLIGGATTSRVHTAVKIDPNYQGGPVVHVNDASRAVGVASSLL
SPERKDAYAADIRTEYQKIAAAHLRGQADKKRLSLADARANAPKIDFANARPVKPTFLGTKTFVDYDLAELVPYIDWTPF
FQTWELAGRFPAILDDAKVGEAARALYDDAQKMLKQIVDEKWFTARAAIGFWPANAVGDDIVLYADDSRTKTVATMHTLR
QQLEKREGRFNTALSDFVAPMDSGVPDYVGGFVVTTGLGEDAVADRFKNANDDYSSILVKALADRLAEAFAERLHARVRR
EFWAYAPDEALSADDLILEKYQGIRPAPGYPAQPDHTEKATLFKLLDAETSAGVRLTESFAMWPGSSVSGLYFASPESFY
FGVGKIERDQVEDYAARKGMTVAEVERWLAPILNYIPARGGQAAQTPRAAATLAPANDAELASHPPGCACAVHLAWRKKA
VGAK
>Mature_1283_residues
SSPVSTARSAFLAAAAKRILILDGAMGTMIQALQFDEAAFRSERFKDFHRDLRGNNDLLILTQPDAIEDIHAQYLRAGAD
IVATNTFSATSIAQADYDLSDIIYELNREGARLARNAATRVAAEDGKPRFVAGAMGPTNRTASISPDVSNPGYRAVTFDD
LRLAYGEQARGLLDGGADILLVETIFDTLNAKAALYAIAELCEARGIDVPVMISGTITDKSGRLLSGQMPEAFWNSVRHA
KPLTIGFNCALGAEDLRAHVADIGRVADTLVCAYPNAGLPNEFGQYDETPAYMARLIGEFARDGLVNIVGGCCGTTPDHI
AAIAAAVAPHKPRIVLDIAPRLRLSGLEPFELTPEIPFVNVGERTNVTGSAKFRKLITAGDYTAALQVARDQVENGAQVI
DVNMDEGLLDSEAAMRTFLNLVAAEPDIARVPVMVDSSKFHVIEAGLKCVQGKPVVNSISLKEGEEKFIHEAQIARRHGA
AVVVMAFDETGQADTYQRKTEICARAYKILVETVGFPPEDIIFDPNIFAIATGIEEHDNYGVDFIEATRWIRQNLPHAHV
SGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPELRQVCEDVVLNRDPGASERLLALAEKF
RGQGKQTKEADLAWREWPVEKRLSHALVHGITEFIDVDTEEARAKSTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVVK
SARVMKQAVAYLMPFMEAEKAANKGRANERSNAGKIVLATVKGDVHDIGKNIVGIVLQCNNFEVIDLGVMVPAAKIIDTA
KAENADIIGLSGLITPSLDEMAYLASEMERQGLNVPLLIGGATTSRVHTAVKIDPNYQGGPVVHVNDASRAVGVASSLLS
PERKDAYAADIRTEYQKIAAAHLRGQADKKRLSLADARANAPKIDFANARPVKPTFLGTKTFVDYDLAELVPYIDWTPFF
QTWELAGRFPAILDDAKVGEAARALYDDAQKMLKQIVDEKWFTARAAIGFWPANAVGDDIVLYADDSRTKTVATMHTLRQ
QLEKREGRFNTALSDFVAPMDSGVPDYVGGFVVTTGLGEDAVADRFKNANDDYSSILVKALADRLAEAFAERLHARVRRE
FWAYAPDEALSADDLILEKYQGIRPAPGYPAQPDHTEKATLFKLLDAETSAGVRLTESFAMWPGSSVSGLYFASPESFYF
GVGKIERDQVEDYAARKGMTVAEVERWLAPILNYIPARGGQAAQTPRAAATLAPANDAELASHPPGCACAVHLAWRKKAV
GAK

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1249, Percent_Identity=57.6461168935148, Blast_Score=1427, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1238, Percent_Identity=61.1470113085622, Blast_Score=1508, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=323, Percent_Identity=25.6965944272446, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17535405, Length=1236, Percent_Identity=56.8770226537217, Blast_Score=1369, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 139432; Mature: 139301

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPVSTARSAFLAAAAKRILILDGAMGTMIQALQFDEAAFRSERFKDFHRDLRGNNDLL
CCCCHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ILTQPDAIEDIHAQYLRAGADIVATNTFSATSIAQADYDLSDIIYELNREGARLARNAAT
EEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
RVAAEDGKPRFVAGAMGPTNRTASISPDVSNPGYRAVTFDDLRLAYGEQARGLLDGGADI
HHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCHHHCHHHCCCCCE
LLVETIFDTLNAKAALYAIAELCEARGIDVPVMISGTITDKSGRLLSGQMPEAFWNSVRH
EEHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEECCCCCHHHHHHHHC
AKPLTIGFNCALGAEDLRAHVADIGRVADTLVCAYPNAGLPNEFGQYDETPAYMARLIGE
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHCCCCCCHHHHHHHHHH
FARDGLVNIVGGCCGTTPDHIAAIAAAVAPHKPRIVLDIAPRLRLSGLEPFELTPEIPFV
HHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCEE
NVGERTNVTGSAKFRKLITAGDYTAALQVARDQVENGAQVIDVNMDEGLLDSEAAMRTFL
ECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
NLVAAEPDIARVPVMVDSSKFHVIEAGLKCVQGKPVVNSISLKEGEEKFIHEAQIARRHG
HHHHCCCCCEECCEEECCCCEEEEHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCC
AAVVVMAFDETGQADTYQRKTEICARAYKILVETVGFPPEDIIFDPNIFAIATGIEEHDN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHCCC
YGVDFIEATRWIRQNLPHAHVSGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIV
CCCHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEE
NAGQMIVYDDIDPELRQVCEDVVLNRDPGASERLLALAEKFRGQGKQTKEADLAWREWPV
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCHHHHCCH
EKRLSHALVHGITEFIDVDTEEARAKSTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVV
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHH
KSARVMKQAVAYLMPFMEAEKAANKGRANERSNAGKIVLATVKGDVHDIGKNIVGIVLQC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEEEE
NNFEVIDLGVMVPAAKIIDTAKAENADIIGLSGLITPSLDEMAYLASEMERQGLNVPLLI
CCEEEEEECHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEE
GGATTSRVHTAVKIDPNYQGGPVVHVNDASRAVGVASSLLSPERKDAYAADIRTEYQKIA
ECCCCCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AAHLRGQADKKRLSLADARANAPKIDFANARPVKPTFLGTKTFVDYDLAELVPYIDWTPF
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHCCCHHHHHCCCCCCCH
FQTWELAGRFPAILDDAKVGEAARALYDDAQKMLKQIVDEKWFTARAAIGFWPANAVGDD
HHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
IVLYADDSRTKTVATMHTLRQQLEKREGRFNTALSDFVAPMDSGVPDYVGGFVVTTGLGE
EEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCEEEEECCCC
DAVADRFKNANDDYSSILVKALADRLAEAFAERLHARVRREFWAYAPDEALSADDLILEK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
YQGIRPAPGYPAQPDHTEKATLFKLLDAETSAGVRLTESFAMWPGSSVSGLYFASPESFY
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHEECCCCCCCEEEEECCCCEE
FGVGKIERDQVEDYAARKGMTVAEVERWLAPILNYIPARGGQAAQTPRAAATLAPANDAE
EECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCH
LASHPPGCACAVHLAWRKKAVGAK
HCCCCCCCEEEEEHHHHHHCCCCC
>Mature Secondary Structure 
SSPVSTARSAFLAAAAKRILILDGAMGTMIQALQFDEAAFRSERFKDFHRDLRGNNDLL
CCCHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ILTQPDAIEDIHAQYLRAGADIVATNTFSATSIAQADYDLSDIIYELNREGARLARNAAT
EEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
RVAAEDGKPRFVAGAMGPTNRTASISPDVSNPGYRAVTFDDLRLAYGEQARGLLDGGADI
HHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCHHHCHHHCCCCCE
LLVETIFDTLNAKAALYAIAELCEARGIDVPVMISGTITDKSGRLLSGQMPEAFWNSVRH
EEHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEECCCCCHHHHHHHHC
AKPLTIGFNCALGAEDLRAHVADIGRVADTLVCAYPNAGLPNEFGQYDETPAYMARLIGE
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHCCCCCCHHHHHHHHHH
FARDGLVNIVGGCCGTTPDHIAAIAAAVAPHKPRIVLDIAPRLRLSGLEPFELTPEIPFV
HHHCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCEE
NVGERTNVTGSAKFRKLITAGDYTAALQVARDQVENGAQVIDVNMDEGLLDSEAAMRTFL
ECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHH
NLVAAEPDIARVPVMVDSSKFHVIEAGLKCVQGKPVVNSISLKEGEEKFIHEAQIARRHG
HHHHCCCCCEECCEEECCCCEEEEHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCC
AAVVVMAFDETGQADTYQRKTEICARAYKILVETVGFPPEDIIFDPNIFAIATGIEEHDN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHCCC
YGVDFIEATRWIRQNLPHAHVSGGVSNLSFSFRGNEPVREAMHSVFLYHAIKAGMDMGIV
CCCHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEE
NAGQMIVYDDIDPELRQVCEDVVLNRDPGASERLLALAEKFRGQGKQTKEADLAWREWPV
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCHHHHCCH
EKRLSHALVHGITEFIDVDTEEARAKSTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVV
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHH
KSARVMKQAVAYLMPFMEAEKAANKGRANERSNAGKIVLATVKGDVHDIGKNIVGIVLQC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEEEE
NNFEVIDLGVMVPAAKIIDTAKAENADIIGLSGLITPSLDEMAYLASEMERQGLNVPLLI
CCEEEEEECHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEE
GGATTSRVHTAVKIDPNYQGGPVVHVNDASRAVGVASSLLSPERKDAYAADIRTEYQKIA
ECCCCCCEEEEEEECCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AAHLRGQADKKRLSLADARANAPKIDFANARPVKPTFLGTKTFVDYDLAELVPYIDWTPF
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHCCCHHHHHCCCCCCCH
FQTWELAGRFPAILDDAKVGEAARALYDDAQKMLKQIVDEKWFTARAAIGFWPANAVGDD
HHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
IVLYADDSRTKTVATMHTLRQQLEKREGRFNTALSDFVAPMDSGVPDYVGGFVVTTGLGE
EEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCEEEEECCCC
DAVADRFKNANDDYSSILVKALADRLAEAFAERLHARVRREFWAYAPDEALSADDLILEK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
YQGIRPAPGYPAQPDHTEKATLFKLLDAETSAGVRLTESFAMWPGSSVSGLYFASPESFY
HCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHEECCCCCCCEEEEECCCCEE
FGVGKIERDQVEDYAARKGMTVAEVERWLAPILNYIPARGGQAAQTPRAAATLAPANDAE
EECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCH
LASHPPGCACAVHLAWRKKAVGAK
HCCCCCCCEEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]