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The map label for this gene is siaT [H]

Identifier: 146338063

GI number: 146338063

Start: 1016881

End: 1018200

Strand: Direct

Name: siaT [H]

Synonym: BRADO0958

Alternate gene names: 146338063

Gene position: 1016881-1018200 (Clockwise)

Preceding gene: 146338062

Following gene: 146338064

Centisome position: 13.64

GC content: 65.83

Gene sequence:

>1320_bases
ATGAGCACGGATGCGGTCGCCGTCATCGGCTTCGTTGCCCTGTTCGCCCTGATGCTCTTGCGCGTGCCGGTCGGCATGGC
GATGGGGCTCGTCGGCGTCTCCGGCTTCGCTTATCTCGTCAACGGCACGGCGGCGCTGAAGCTGGTCGGCCAGACCTCGA
TGCGCACGGTCACGGACTACACCTTCGGCGTCATCCCGATGTTCCTGCTGATGGGAACGTTCGTCTCCAACTCCGGCATG
AGCCGCGAGCTGTTCCGCGCCGCCAACGGCTTCGTCGGCCATCTGCGCGGCGGCCTGGGCATCGCTACCGTGGCGGCCTG
CGGCGGCTTCGCCGCGATCTGCGGCTCGTCGGTCGCGACCGCCGCGACGTTCTCCGCGGTGGCCTATCCGGAGATGCGCC
GCTTCGGCTATCCGCAATCCTTCGCCACCGGCGTCATCGCCGCCGGCGGCACGCTCGGCGCCATGTTGCCGCCGTCCACC
GTGCTCGCCGTCTACGGTATCATCACCGAGCAGGACATCGGCAAGCTGTTCATCGCCGGCATCATCCCGGGCCTGCTGGC
GATGACCATGTACATGATCACCATCACGGTGATCGGCAAGGTCAGGCCGGACTTCCTGCCGAAGGGCGAGGCGCCGCCGT
GGCGCGAGCGCATCGCGGGGCTGAAGGGCATCTGGGCGCCGGTGCTGCTGTTCCTGTTCGTGATCGGCGGCCTCTATGGT
CTCCCATTCTTGCCGCGCTTCACGCCGACCGAGGCCGGCGGCGTCGGCGCCACCGGCGCGTTCCTGATCGGCGTGTTCAC
CGGCCGGCTGAACAAGGAGAAGATCCTGGCCTCGCTGCTGCAGGCGACGCGCACCGCGGCGGCCGTCTTCACCGTGCTGA
TCGGCGCGCTGATCTTCGGCTACTTCCTCACGGTGACGCAGACGCCGCAGAAGGTGACGGAATTCCTCACCGGCCTCGGC
CTCGGCCCCTACGGCGTGCTGGCGCTGATCATGGTGATGTATCTCGTGCTCGGCTGCCTGATGGACGCCATGGCGATGAT
CATTCTCACCGTGCCGATCATCTTCCCGGTGATCTCGCATCTCGGCTTCGATCCGATCTGGTTCGGCGTCATCATCGTGA
TGACTGTCGAGCTCGGCCTGATCCATCCGCCGGTCGGCATGAACGTCTTCGTGATCAAATCCGTGGTGAAGGACGTGTCA
TTCTCGACGATCTTCAAGGGCGTGCTGCCCTTTGTCGCCACCGACCTGATCCGCCTGGTGATCCTGATCGCCTTCCCGCT
GCTCGCCACCTGGCTGCCGCAACAGATGATGAACCGATGA

Upstream 100 bases:

>100_bases
CGTCTCGGCGGTGCTGTTGATCGCCATCCGGACCTATCGCCTGATCTTCCATCCCGAGGAGATTCATGAACCTCACGTCA
AGCCCACGGAGTAGGGCCGC

Downstream 100 bases:

>100_bases
CCGCGCCCGTTCTCGAAACCCGCTATGTCTTCACCCTCACCGTGATGATCGGCGCCGTCACCTCGGCCGGCGAGACCGGC
ATCGGCGTGCGCCGGATCAT

Product: TRAP dicarboxylate family transporter DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSTDAVAVIGFVALFALMLLRVPVGMAMGLVGVSGFAYLVNGTAALKLVGQTSMRTVTDYTFGVIPMFLLMGTFVSNSGM
SRELFRAANGFVGHLRGGLGIATVAACGGFAAICGSSVATAATFSAVAYPEMRRFGYPQSFATGVIAAGGTLGAMLPPST
VLAVYGIITEQDIGKLFIAGIIPGLLAMTMYMITITVIGKVRPDFLPKGEAPPWRERIAGLKGIWAPVLLFLFVIGGLYG
LPFLPRFTPTEAGGVGATGAFLIGVFTGRLNKEKILASLLQATRTAAAVFTVLIGALIFGYFLTVTQTPQKVTEFLTGLG
LGPYGVLALIMVMYLVLGCLMDAMAMIILTVPIIFPVISHLGFDPIWFGVIIVMTVELGLIHPPVGMNVFVIKSVVKDVS
FSTIFKGVLPFVATDLIRLVILIAFPLLATWLPQQMMNR

Sequences:

>Translated_439_residues
MSTDAVAVIGFVALFALMLLRVPVGMAMGLVGVSGFAYLVNGTAALKLVGQTSMRTVTDYTFGVIPMFLLMGTFVSNSGM
SRELFRAANGFVGHLRGGLGIATVAACGGFAAICGSSVATAATFSAVAYPEMRRFGYPQSFATGVIAAGGTLGAMLPPST
VLAVYGIITEQDIGKLFIAGIIPGLLAMTMYMITITVIGKVRPDFLPKGEAPPWRERIAGLKGIWAPVLLFLFVIGGLYG
LPFLPRFTPTEAGGVGATGAFLIGVFTGRLNKEKILASLLQATRTAAAVFTVLIGALIFGYFLTVTQTPQKVTEFLTGLG
LGPYGVLALIMVMYLVLGCLMDAMAMIILTVPIIFPVISHLGFDPIWFGVIIVMTVELGLIHPPVGMNVFVIKSVVKDVS
FSTIFKGVLPFVATDLIRLVILIAFPLLATWLPQQMMNR
>Mature_438_residues
STDAVAVIGFVALFALMLLRVPVGMAMGLVGVSGFAYLVNGTAALKLVGQTSMRTVTDYTFGVIPMFLLMGTFVSNSGMS
RELFRAANGFVGHLRGGLGIATVAACGGFAAICGSSVATAATFSAVAYPEMRRFGYPQSFATGVIAAGGTLGAMLPPSTV
LAVYGIITEQDIGKLFIAGIIPGLLAMTMYMITITVIGKVRPDFLPKGEAPPWRERIAGLKGIWAPVLLFLFVIGGLYGL
PFLPRFTPTEAGGVGATGAFLIGVFTGRLNKEKILASLLQATRTAAAVFTVLIGALIFGYFLTVTQTPQKVTEFLTGLGL
GPYGVLALIMVMYLVLGCLMDAMAMIILTVPIIFPVISHLGFDPIWFGVIIVMTVELGLIHPPVGMNVFVIKSVVKDVSF
STIFKGVLPFVATDLIRLVILIAFPLLATWLPQQMMNR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=31.1224489795918, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46426; Mature: 46295

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STDAVAVIGFVALFALMLLRVPVGMAMGLVGVSGFAYLVNGTAALKLVGQTSMRTVTDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHH
TFGVIPMFLLMGTFVSNSGMSRELFRAANGFVGHLRGGLGIATVAACGGFAAICGSSVAT
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHH
AATFSAVAYPEMRRFGYPQSFATGVIAAGGTLGAMLPPSTVLAVYGIITEQDIGKLFIAG
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IIPGLLAMTMYMITITVIGKVRPDFLPKGEAPPWRERIAGLKGIWAPVLLFLFVIGGLYG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHC
LPFLPRFTPTEAGGVGATGAFLIGVFTGRLNKEKILASLLQATRTAAAVFTVLIGALIFG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFLTVTQTPQKVTEFLTGLGLGPYGVLALIMVMYLVLGCLMDAMAMIILTVPIIFPVISH
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFDPIWFGVIIVMTVELGLIHPPVGMNVFVIKSVVKDVSFSTIFKGVLPFVATDLIRLV
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILIAFPLLATWLPQQMMNR
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]