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The map label for this gene is acdA [H]

Identifier: 146338043

GI number: 146338043

Start: 1001292

End: 1002539

Strand: Direct

Name: acdA [H]

Synonym: BRADO0936

Alternate gene names: 146338043

Gene position: 1001292-1002539 (Clockwise)

Preceding gene: 146338042

Following gene: 146338044

Centisome position: 13.43

GC content: 66.19

Gene sequence:

>1248_bases
ATGAACTTCGACGACACCCCGCAGGAAGCCGCCTTTCGCGAGACCGCGCGCGCCTGGGTCGCGGCGAATGCGCCGAAGGA
GCTGGAGGTGGAGCTTGCGAGCTCCTCGCTCGGACGCATTCGGCTGAAGCACGCCGACATCGTCGAGGTCGGCAAGGCCT
GGCAGAAGAAGAAGTCCGACGCCGGCTGGGCCTGCCTGCACTGGCCGAAGGAGTATGGCGGCCGCGGCGCGACGCCGATC
GAGCGGGTGATCTGGCAGCAGGAGGAGGGCGTCTACGGCAAGCTGACGCAGCCGTTTCAGATCGGCGAGGGCATGTGCGG
CCCGACCGTGATGGCCTATGGCAGCGAAGAGCACAAGCGCCGCTATCTGCCGAAGCTCGCCTCGGGCGAGGAGATCTGGT
GCCAGCTGTTCTCCGAGCCGGCCGGCGGTTCGGACGTTGCGGGCCTGCGCACCCGCGCCGAGAAGCGCGGCGACGACTGG
GTCATCAACGGCCAGAAGATCTGGACGTCCGGCGCGCATTACTCCGACTACGGCCTCTTGATCACGCGCACCGATCCCAA
CGTGCCGAAGCACAAGGGGCTCACGATGTTCTTCCTGGACATGAAGAGCCCCGGCGTCGAGGTCCGCCCGATCAAGCAGG
CCAACGGCATGCAGGAGTTCAACGAGGTCTATTTCACCGACGTCGTGATTCCGGACTCGCAGCGCCTCGGAGCGGTCGGC
GACGGCTGGAACGTATCGCTGACCACCTTGATGAACGAGCGCATGTCGATCGGCGCGCGGCTCGCCACCGGCTTCCCCGA
GATGTTCGAGTTCTGCGCCAACCTGATGACCGACAACGGTCTCGCCATCGACGATCGCGCCACGCGCTCCAGGCTCGCGT
CGTGGGCGGTGAAGGCGAGCGGACTGAAATATACGAGCTACCGCGCGATCTCGGCGCTGTCCAAAGGCGATCGGCCGGGG
CCAGAAAATTCGATCGGCAAGCTGGTCGCCGGCGTCATGCTGCAGGACATCGCGACCTACGCGATGGACCTCGAAGGCGC
GGCCGGCGTGCTCACCGGTGCGGACGAGGCGGAGACGCAGGGACAGTTCCAGCAGATGCTGCTGACGTCGCCCTCGATGC
GCATCGCCGGCGGCACCGACGAGATCCTGCGCAACATCATCGCCGAGCGCGTGCTCGGCCTGCCCGGCGATATCCGCGTC
GACAAGGATGTGCCGTTCAACAAGGTCCCGACCAAGGGACGTAGTTAG

Upstream 100 bases:

>100_bases
GTTAGCGCCGCGTAACCCGCCGATGGCTTAACGAAGCCAGGGATTTGGCGGGTTACGCCTTCGGCTAATCCGCTCTACGA
ATACAAGTGAGGGCTGAGGC

Downstream 100 bases:

>100_bases
ACCCTCATCCTGAGGAACTGCGCAGCAGCGTCTCGAAGGATGAGGCCCGCGATGTGGCCTCATGGTTCGAGACGGCGCTG
CGCGCCTCCTCACCATGAGG

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MNFDDTPQEAAFRETARAWVAANAPKELEVELASSSLGRIRLKHADIVEVGKAWQKKKSDAGWACLHWPKEYGGRGATPI
ERVIWQQEEGVYGKLTQPFQIGEGMCGPTVMAYGSEEHKRRYLPKLASGEEIWCQLFSEPAGGSDVAGLRTRAEKRGDDW
VINGQKIWTSGAHYSDYGLLITRTDPNVPKHKGLTMFFLDMKSPGVEVRPIKQANGMQEFNEVYFTDVVIPDSQRLGAVG
DGWNVSLTTLMNERMSIGARLATGFPEMFEFCANLMTDNGLAIDDRATRSRLASWAVKASGLKYTSYRAISALSKGDRPG
PENSIGKLVAGVMLQDIATYAMDLEGAAGVLTGADEAETQGQFQQMLLTSPSMRIAGGTDEILRNIIAERVLGLPGDIRV
DKDVPFNKVPTKGRS

Sequences:

>Translated_415_residues
MNFDDTPQEAAFRETARAWVAANAPKELEVELASSSLGRIRLKHADIVEVGKAWQKKKSDAGWACLHWPKEYGGRGATPI
ERVIWQQEEGVYGKLTQPFQIGEGMCGPTVMAYGSEEHKRRYLPKLASGEEIWCQLFSEPAGGSDVAGLRTRAEKRGDDW
VINGQKIWTSGAHYSDYGLLITRTDPNVPKHKGLTMFFLDMKSPGVEVRPIKQANGMQEFNEVYFTDVVIPDSQRLGAVG
DGWNVSLTTLMNERMSIGARLATGFPEMFEFCANLMTDNGLAIDDRATRSRLASWAVKASGLKYTSYRAISALSKGDRPG
PENSIGKLVAGVMLQDIATYAMDLEGAAGVLTGADEAETQGQFQQMLLTSPSMRIAGGTDEILRNIIAERVLGLPGDIRV
DKDVPFNKVPTKGRS
>Mature_415_residues
MNFDDTPQEAAFRETARAWVAANAPKELEVELASSSLGRIRLKHADIVEVGKAWQKKKSDAGWACLHWPKEYGGRGATPI
ERVIWQQEEGVYGKLTQPFQIGEGMCGPTVMAYGSEEHKRRYLPKLASGEEIWCQLFSEPAGGSDVAGLRTRAEKRGDDW
VINGQKIWTSGAHYSDYGLLITRTDPNVPKHKGLTMFFLDMKSPGVEVRPIKQANGMQEFNEVYFTDVVIPDSQRLGAVG
DGWNVSLTTLMNERMSIGARLATGFPEMFEFCANLMTDNGLAIDDRATRSRLASWAVKASGLKYTSYRAISALSKGDRPG
PENSIGKLVAGVMLQDIATYAMDLEGAAGVLTGADEAETQGQFQQMLLTSPSMRIAGGTDEILRNIIAERVLGLPGDIRV
DKDVPFNKVPTKGRS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=397, Percent_Identity=24.1813602015113, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4557231, Length=397, Percent_Identity=24.1813602015113, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4501859, Length=267, Percent_Identity=28.0898876404494, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=26.4204545454545, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226958412, Length=206, Percent_Identity=31.0679611650485, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=206, Percent_Identity=31.0679611650485, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=27.2206303724928, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7656849, Length=349, Percent_Identity=24.0687679083095, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501857, Length=198, Percent_Identity=28.7878787878788, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI76496475, Length=222, Percent_Identity=31.0810810810811, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4557235, Length=222, Percent_Identity=31.0810810810811, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI38505218, Length=291, Percent_Identity=23.7113402061856, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI211971008, Length=295, Percent_Identity=23.3898305084746, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI48976061, Length=295, Percent_Identity=23.3898305084746, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=25.5014326647564, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786223, Length=336, Percent_Identity=23.5119047619048, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=264, Percent_Identity=31.4393939393939, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17570075, Length=409, Percent_Identity=26.4058679706601, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=342, Percent_Identity=27.7777777777778, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17534899, Length=347, Percent_Identity=25.0720461095101, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=271, Percent_Identity=28.0442804428044, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=336, Percent_Identity=24.4047619047619, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=334, Percent_Identity=23.6526946107784, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=203, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=199, Percent_Identity=28.643216080402, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=205, Percent_Identity=28.780487804878, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=216, Percent_Identity=27.3148148148148, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=348, Percent_Identity=24.7126436781609, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=157, Percent_Identity=31.2101910828025, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=157, Percent_Identity=31.2101910828025, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=362, Percent_Identity=24.8618784530387, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281363737, Length=352, Percent_Identity=26.9886363636364, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355753, Length=344, Percent_Identity=25, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646207, Length=361, Percent_Identity=26.8698060941828, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24666513, Length=295, Percent_Identity=24.7457627118644, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356377, Length=214, Percent_Identity=24.7663551401869, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45539; Mature: 45539

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDDTPQEAAFRETARAWVAANAPKELEVELASSSLGRIRLKHADIVEVGKAWQKKKSD
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCC
AGWACLHWPKEYGGRGATPIERVIWQQEEGVYGKLTQPFQIGEGMCGPTVMAYGSEEHKR
CCEEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEECCCHHHHH
RYLPKLASGEEIWCQLFSEPAGGSDVAGLRTRAEKRGDDWVINGQKIWTSGAHYSDYGLL
HHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEECCCEEEECCCCCCCCEEE
ITRTDPNVPKHKGLTMFFLDMKSPGVEVRPIKQANGMQEFNEVYFTDVVIPDSQRLGAVG
EECCCCCCCCCCCCEEEEEECCCCCCEEEECHHHCCHHHHHHEEEEEEEECCCCCCCCCC
DGWNVSLTTLMNERMSIGARLATGFPEMFEFCANLMTDNGLAIDDRATRSRLASWAVKAS
CCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHC
GLKYTSYRAISALSKGDRPGPENSIGKLVAGVMLQDIATYAMDLEGAAGVLTGADEAETQ
CCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
GQFQQMLLTSPSMRIAGGTDEILRNIIAERVLGLPGDIRVDKDVPFNKVPTKGRS
HHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNFDDTPQEAAFRETARAWVAANAPKELEVELASSSLGRIRLKHADIVEVGKAWQKKKSD
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCC
AGWACLHWPKEYGGRGATPIERVIWQQEEGVYGKLTQPFQIGEGMCGPTVMAYGSEEHKR
CCEEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCEEEECCCHHHHH
RYLPKLASGEEIWCQLFSEPAGGSDVAGLRTRAEKRGDDWVINGQKIWTSGAHYSDYGLL
HHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEECCCEEEECCCCCCCCEEE
ITRTDPNVPKHKGLTMFFLDMKSPGVEVRPIKQANGMQEFNEVYFTDVVIPDSQRLGAVG
EECCCCCCCCCCCCEEEEEECCCCCCEEEECHHHCCHHHHHHEEEEEEEECCCCCCCCCC
DGWNVSLTTLMNERMSIGARLATGFPEMFEFCANLMTDNGLAIDDRATRSRLASWAVKAS
CCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHC
GLKYTSYRAISALSKGDRPGPENSIGKLVAGVMLQDIATYAMDLEGAAGVLTGADEAETQ
CCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHH
GQFQQMLLTSPSMRIAGGTDEILRNIIAERVLGLPGDIRVDKDVPFNKVPTKGRS
HHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]