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The map label for this gene is cobT [H]

Identifier: 146337937

GI number: 146337937

Start: 879242

End: 880219

Strand: Reverse

Name: cobT [H]

Synonym: BRADO0827

Alternate gene names: 146337937

Gene position: 880219-879242 (Counterclockwise)

Preceding gene: 146337938

Following gene: 146337936

Centisome position: 11.8

GC content: 67.69

Gene sequence:

>978_bases
TTGACCTGGCGTGACGTCGCCCTGACGCTCTTCCTGATGGCCATGATTGCGCTGGTGCTCGCGCCGGGTTTTCCGCCGCG
GCGCCGTCGCACGGTGCGCCAGCCCGTGCCGCTCGATCCCCATCGTCCCTACCAGGCCTACACCAGGGAGTTCGACGTCG
AGGTCGACGCCAACGGCCTGGAGAGCTTCTTCGCCGCGCTCGGTGATGATGAGCGGCGCTTGTCTGAGCGCTATCCCCCG
CTCGATCCCGCTCCCTTGTTCGCGCTCGACGAGGAGCTGGCTGCGCGGCGCGCGAACGCATGCGCAGCGTCCGCGCCGAT
GCGCGCGGATGACGCCGCGGTCACGTTGCTCATCGACCATTCCGGATCGATGCGCGGAGATCCCATCCTCCACGCTGCGC
GCGCCGCCCTCGTCGCCTCCGACTTGCTGGCGCGCGTCGGCGCCACCCAGGAGGTGCTCGGCTTCACCACCACGCGCTGG
AGGGGCGGACGGAGCCGGGAGAAATGGCTGAAGAACGGACAGCCGTCTTATCCGGGACGGCTGAACGACCTGCTGCACAT
CGTCTATTGCCGCGCCGGCGAGACGCTGACCGCCGCGCAATGTGCACCGATGCTGTGGCCGGGCCTGCTCAAGGAGAACG
TCGATGGCGAGGCGGTCGCCTGGGCCGTAGCGCGGCTGCGACAACGTCGCGAGCCGCGCAAATATCTCATCATCCTGTCA
GACGGCGCGCCAGTCGACGATTCCACGATCTTGGAGAACGGCAACGGCTATCTGAGCCAGCATCTGCGGGCCGTGATCGC
CGAGATAGAGCGCGAAGGCGACATCCTGGTCGCGGCGATCGGGATCGGCGACCACGTCGCTCAGCACTATCGGCGGTGCG
TCACGATCGGCTCTCCCGCGGAATGGGAAGAGGCGCTCGTGCAGCTGATCGAACGCCTGCTGCAAGGCTCCTTCGGCGAC
AACCTCCCCTCGCCGTAG

Upstream 100 bases:

>100_bases
GTGGCGGCGGTGGTGATGGCGGAGGCGGTGGCGGCTGCGGCGGCTGCAGCTGAGCCGCTTCCAGCCTCGCCCGTGCCGCC
AAGATGGATCGGAAGTCGGC

Downstream 100 bases:

>100_bases
ATTCACCGGCGTTGCGCAAGGGGCCACCGCCGGCACACCGTATTTTTTCGGGCCCGCCTGATTTCGTCTGCACGTCATCG
TACTCATTAGTTCGTTGTCA

Product: putative cobalamin biosynthesis protein CobT

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTWRDVALTLFLMAMIALVLAPGFPPRRRRTVRQPVPLDPHRPYQAYTREFDVEVDANGLESFFAALGDDERRLSERYPP
LDPAPLFALDEELAARRANACAASAPMRADDAAVTLLIDHSGSMRGDPILHAARAALVASDLLARVGATQEVLGFTTTRW
RGGRSREKWLKNGQPSYPGRLNDLLHIVYCRAGETLTAAQCAPMLWPGLLKENVDGEAVAWAVARLRQRREPRKYLIILS
DGAPVDDSTILENGNGYLSQHLRAVIAEIEREGDILVAAIGIGDHVAQHYRRCVTIGSPAEWEEALVQLIERLLQGSFGD
NLPSP

Sequences:

>Translated_325_residues
MTWRDVALTLFLMAMIALVLAPGFPPRRRRTVRQPVPLDPHRPYQAYTREFDVEVDANGLESFFAALGDDERRLSERYPP
LDPAPLFALDEELAARRANACAASAPMRADDAAVTLLIDHSGSMRGDPILHAARAALVASDLLARVGATQEVLGFTTTRW
RGGRSREKWLKNGQPSYPGRLNDLLHIVYCRAGETLTAAQCAPMLWPGLLKENVDGEAVAWAVARLRQRREPRKYLIILS
DGAPVDDSTILENGNGYLSQHLRAVIAEIEREGDILVAAIGIGDHVAQHYRRCVTIGSPAEWEEALVQLIERLLQGSFGD
NLPSP
>Mature_324_residues
TWRDVALTLFLMAMIALVLAPGFPPRRRRTVRQPVPLDPHRPYQAYTREFDVEVDANGLESFFAALGDDERRLSERYPPL
DPAPLFALDEELAARRANACAASAPMRADDAAVTLLIDHSGSMRGDPILHAARAALVASDLLARVGATQEVLGFTTTRWR
GGRSREKWLKNGQPSYPGRLNDLLHIVYCRAGETLTAAQCAPMLWPGLLKENVDGEAVAWAVARLRQRREPRKYLIILSD
GAPVDDSTILENGNGYLSQHLRAVIAEIEREGDILVAAIGIGDHVAQHYRRCVTIGSPAEWEEALVQLIERLLQGSFGDN
LPSP

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG4547

COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006538
- InterPro:   IPR002035 [H]

Pfam domain/function: PF06213 CobT [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 35899; Mature: 35768

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWRDVALTLFLMAMIALVLAPGFPPRRRRTVRQPVPLDPHRPYQAYTREFDVEVDANGL
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHCCEEECCHHH
ESFFAALGDDERRLSERYPPLDPAPLFALDEELAARRANACAASAPMRADDAAVTLLIDH
HHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
SGSMRGDPILHAARAALVASDLLARVGATQEVLGFTTTRWRGGRSREKWLKNGQPSYPGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCHHHHHHCCCCCCCCH
LNDLLHIVYCRAGETLTAAQCAPMLWPGLLKENVDGEAVAWAVARLRQRREPRKYLIILS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
DGAPVDDSTILENGNGYLSQHLRAVIAEIEREGDILVAAIGIGDHVAQHYRRCVTIGSPA
CCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCH
EWEEALVQLIERLLQGSFGDNLPSP
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TWRDVALTLFLMAMIALVLAPGFPPRRRRTVRQPVPLDPHRPYQAYTREFDVEVDANGL
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHCCEEECCHHH
ESFFAALGDDERRLSERYPPLDPAPLFALDEELAARRANACAASAPMRADDAAVTLLIDH
HHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
SGSMRGDPILHAARAALVASDLLARVGATQEVLGFTTTRWRGGRSREKWLKNGQPSYPGR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCCHHHHHHCCCCCCCCH
LNDLLHIVYCRAGETLTAAQCAPMLWPGLLKENVDGEAVAWAVARLRQRREPRKYLIILS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
DGAPVDDSTILENGNGYLSQHLRAVIAEIEREGDILVAAIGIGDHVAQHYRRCVTIGSPA
CCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCH
EWEEALVQLIERLLQGSFGDNLPSP
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]