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The map label for this gene is cheW [H]

Identifier: 146337931

GI number: 146337931

Start: 871952

End: 872440

Strand: Reverse

Name: cheW [H]

Synonym: BRADO0821

Alternate gene names: 146337931

Gene position: 872440-871952 (Counterclockwise)

Preceding gene: 146337932

Following gene: 146337930

Centisome position: 11.7

GC content: 64.62

Gene sequence:

>489_bases
ATGAGCGAAACGGCTCAATATCTGACGCTCGGTCTCGACGGCGAAACCTTCGGCATCAGCATCCGCAACGTGCGCGAGAT
TCTCGACATGAAGCCGATCTCGCGGCTGCCGCACGCCCCGCACTTCCTGCTCGGCATGATCGATGTTCGCGGCAGCGGCT
ATCCGATCGTCGATCTCCGGCTGAAGCTCGATCTGCCGAGCGTGCCGGCGACGGAGGCGACGCGGATCATCATCCTCGAC
GTGCCGGTCGGCAACCGGCTGGTCGGCGTCGGCTTCGTCGCCGATTGCGTCTTCGAGGTCACCGACATCGACGAGTCCAC
CGTCGAGCCAGTGCCGGAAGTCGGCGGCCGCTGGACGTCCGACTACATCTCCGGGATCGGCCGGAAGGGCGACAGGTTCG
TCGTGCTGTTCGATCTCGCCAAGCTTATGGCTCATACGCGCCTGCCGGTCGCCACGGACCACGGTGGTCATGCCCCAGCT
GCAGCTTAA

Upstream 100 bases:

>100_bases
CGCGGATTTCCACCGCTGATCGCCGCGATCGCGGCGCTCCGCTCGCCCCTGGCGGAGCCCGCAACACCTGACGTTCCGCT
GGCACAGAAGAGGACGACAC

Downstream 100 bases:

>100_bases
GCCGGCCTGGGCGGAACCGTTCGGTTCCGGCGGGACATTGTCCGATGCGCGTTTCCGCGCGCTGTCGCAGCTGATCGAGG
CGCAGGTCGGCATCAAGATG

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSETAQYLTLGLDGETFGISIRNVREILDMKPISRLPHAPHFLLGMIDVRGSGYPIVDLRLKLDLPSVPATEATRIIILD
VPVGNRLVGVGFVADCVFEVTDIDESTVEPVPEVGGRWTSDYISGIGRKGDRFVVLFDLAKLMAHTRLPVATDHGGHAPA
AA

Sequences:

>Translated_162_residues
MSETAQYLTLGLDGETFGISIRNVREILDMKPISRLPHAPHFLLGMIDVRGSGYPIVDLRLKLDLPSVPATEATRIIILD
VPVGNRLVGVGFVADCVFEVTDIDESTVEPVPEVGGRWTSDYISGIGRKGDRFVVLFDLAKLMAHTRLPVATDHGGHAPA
AA
>Mature_161_residues
SETAQYLTLGLDGETFGISIRNVREILDMKPISRLPHAPHFLLGMIDVRGSGYPIVDLRLKLDLPSVPATEATRIIILDV
PVGNRLVGVGFVADCVFEVTDIDESTVEPVPEVGGRWTSDYISGIGRKGDRFVVLFDLAKLMAHTRLPVATDHGGHAPAA
A

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=145, Percent_Identity=31.7241379310345, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17515; Mature: 17384

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETAQYLTLGLDGETFGISIRNVREILDMKPISRLPHAPHFLLGMIDVRGSGYPIVDLR
CCCCCEEEEEECCCCEEEEEHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCEEEEE
LKLDLPSVPATEATRIIILDVPVGNRLVGVGFVADCVFEVTDIDESTVEPVPEVGGRWTS
EEECCCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHEECCCCCCCCCCHHHCCEECH
DYISGIGRKGDRFVVLFDLAKLMAHTRLPVATDHGGHAPAAA
HHHHHCCCCCCEEEEHHHHHHHHHHCCCCEEECCCCCCCCCC
>Mature Secondary Structure 
SETAQYLTLGLDGETFGISIRNVREILDMKPISRLPHAPHFLLGMIDVRGSGYPIVDLR
CCCCEEEEEECCCCEEEEEHHHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCEEEEE
LKLDLPSVPATEATRIIILDVPVGNRLVGVGFVADCVFEVTDIDESTVEPVPEVGGRWTS
EEECCCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHEECCCCCCCCCCHHHCCEECH
DYISGIGRKGDRFVVLFDLAKLMAHTRLPVATDHGGHAPAAA
HHHHHCCCCCCEEEEHHHHHHHHHHCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]