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The map label for this gene is thiE [H]

Identifier: 146337902

GI number: 146337902

Start: 832772

End: 833137

Strand: Direct

Name: thiE [H]

Synonym: BRADO0790

Alternate gene names: 146337902

Gene position: 832772-833137 (Clockwise)

Preceding gene: 146337901

Following gene: 146337903

Centisome position: 11.17

GC content: 64.21

Gene sequence:

>366_bases
ATGCCTTTCGATCTTCGCCTTTATGCCATCGTCGATCCCGAGCAGGCGCGCGGCCGCGACCTCGCGGATCTCGCGCGCCG
TTGTGTCGAAGGCGGCGCGACCCTTGTGCAGCTCCGCGACAAACGTAGTAGTAAAGGCGCGTTCGTCGAACAGGCGCGTG
CGATCAAAAGCGCGCTCGCGCCGCATGGCGCACAACTCATCATTAATGACCGCATCGATGTCGTCCTGGACTCCGGCGCC
GACGGCGTGCATATCGGCCCGGATGACATAACAGCCGAGGACACCGCCGCGTGCTCGGTCCCCGTGCAATCATCGGCCTG
TCGATCAAATCGACGGCCGAAGCCGAGGCAGCCCCTGTGGCCCTGA

Upstream 100 bases:

>100_bases
CGCTCCATCAATGGCACGAGCGCCGAGGATGCATCCATGAAGATGGGAAGCCACTTATGTCTGGGAGTCCTCCTCGGCCC
CTCCCGCGCGCCACCTGTCC

Downstream 100 bases:

>100_bases
TTGATTACGCGGGGTGCGGCGGTGTCTTGCCAGTTCGTCAAAGGAACAGCAGCAAGCGCCGATCGGCCTCGACGGCCTTG
CGCGCATCCTCGCGGTCTTG

Product: putative thiamine-phosphate diphosphorylase

Products: NA

Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MPFDLRLYAIVDPEQARGRDLADLARRCVEGGATLVQLRDKRSSKGAFVEQARAIKSALAPHGAQLIINDRIDVVLDSGA
DGVHIGPDDITAEDTAACSVPVQSSACRSNRRPKPRQPLWP

Sequences:

>Translated_121_residues
MPFDLRLYAIVDPEQARGRDLADLARRCVEGGATLVQLRDKRSSKGAFVEQARAIKSALAPHGAQLIINDRIDVVLDSGA
DGVHIGPDDITAEDTAACSVPVQSSACRSNRRPKPRQPLWP
>Mature_120_residues
PFDLRLYAIVDPEQARGRDLADLARRCVEGGATLVQLRDKRSSKGAFVEQARAIKSALAPHGAQLIINDRIDVVLDSGAD
GVHIGPDDITAEDTAACSVPVQSSACRSNRRPKPRQPLWP

Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TMP-PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022998
- InterPro:   IPR003733 [H]

Pfam domain/function: PF02581 TMP-TENI [H]

EC number: =2.5.1.3 [H]

Molecular weight: Translated: 13098; Mature: 12967

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFDLRLYAIVDPEQARGRDLADLARRCVEGGATLVQLRDKRSSKGAFVEQARAIKSALA
CCCCEEEEEEECCHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
PHGAQLIINDRIDVVLDSGADGVHIGPDDITAEDTAACSVPVQSSACRSNRRPKPRQPLW
CCCCEEEECCCEEEEEECCCCCEEECCCCCCCCCCCEECCCCCCHHHHHCCCCCCCCCCC
P
C
>Mature Secondary Structure 
PFDLRLYAIVDPEQARGRDLADLARRCVEGGATLVQLRDKRSSKGAFVEQARAIKSALA
CCCEEEEEEECCHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
PHGAQLIINDRIDVVLDSGADGVHIGPDDITAEDTAACSVPVQSSACRSNRRPKPRQPLW
CCCCEEEECCCEEEEEECCCCCEEECCCCCCCCCCCEECCCCCCHHHHHCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA