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The map label for this gene is ykcC [H]

Identifier: 146337336

GI number: 146337336

Start: 180504

End: 181550

Strand: Direct

Name: ykcC [H]

Synonym: BRADO0168

Alternate gene names: 146337336

Gene position: 180504-181550 (Clockwise)

Preceding gene: 146337334

Following gene: 146337337

Centisome position: 2.42

GC content: 66.76

Gene sequence:

>1047_bases
ATGTTCGTCTCGATCGTTGTGCCCTGCTACAACGAGGCCGATGGCTTGCGCGAGTTTCATCGCCGGACGACGGCGGCGGC
GCGTGCGCTGTGCGGCAACCGGTTCGAGCTGATCCTGGTCGACGACGGCTCGACCGACCAGACTTGGCCGATCATCAACG
AGCTGCTCGCCGAGGATCGCAACGTCGTCGCGGTCAAGCTGGCGCGCAATCATGGCCATCAGCTGGCGCTCACCGCGGGA
CTGTCCACCGTGCGCGGCGATCTGGTGCTGGTGATCGACGCTGACCTGCAGGATCCGCCGGAGCTGCTGAAGCCGATGTA
CGAGACGATGGCGCGCGAGGGCGCCGACGTCGTCTACGGACAGCGCCGTAGCCGTGCCGGCGAGACCCGCTTCAAGACAT
GGTCGGCGGAAGCGTTCTACCGCCTGCTCGCCCGCATCACCCGCGTGCAGATTCCGGTCGACACCGGCGACTTCCGGCTG
ATGAGCCGGCGCATCTCGGACCAGCTGGTGCAGATGCCGGAGCACGACCGCTTCATCCGCGGCATGGTGGCCTGGCTCGG
CTACAAGCAGGTGGCGTTCGAATACGACCGCGAGCCGCGCTTCGCCGGCAGCACCAAATATCCACTGCTGAAGATGATCA
GCTTCGCCGCCGACGCGCTGATCTCGTTCTCCATGGTGCCGCTGCGGATCGCGACCTATGTCGGGGCGCTCCTGACGACG
GTGCTGAGCTTCGTCGGCGTCGCCGCCGTGATCAGCTGGATCTTCTCCGGCACCGTGCCGGGCTGGACCAGCCTGACGCT
GCTGGTGGTGATGATCTCCTCGGTGCAGCTGCTCGTGCTCGGTCTGATCGGCGAATATGTCGGCCGCATCTACATTCAGT
CCAAGAACCGGCCGCTGTTCATGATCTCGCAGATCCACCGCCGCGGCCGCGTGCCGCAGCTGTCGACCGACCGGCTGCCG
GAGACCGAGAGCCCGCCGCTCAACACCCTGCTGGCGCAGTCCGGGCCGGAGCTGCGCCGCTCGCTGCGCGAGGAGACCTC
GTCGTGA

Upstream 100 bases:

>100_bases
TAACTGCCCGTGCCTGAAAATGCTGGTCGTACCCGGTCGCGGTCGCAAGAGGCCTTGGATTTTGACAGAGCAGCAGGACG
AGACGCCGCGCCCCGGCAGG

Downstream 100 bases:

>100_bases
AGGAGCTGCTGAAGCACCCGGCGCTGTATCAGGCCTATCAGAACGCCGGCGGCTTCTTCGGCGCGCGGATCAAGGCGATC
CGCGACTATCTCACCTTGCG

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MFVSIVVPCYNEADGLREFHRRTTAAARALCGNRFELILVDDGSTDQTWPIINELLAEDRNVVAVKLARNHGHQLALTAG
LSTVRGDLVLVIDADLQDPPELLKPMYETMAREGADVVYGQRRSRAGETRFKTWSAEAFYRLLARITRVQIPVDTGDFRL
MSRRISDQLVQMPEHDRFIRGMVAWLGYKQVAFEYDREPRFAGSTKYPLLKMISFAADALISFSMVPLRIATYVGALLTT
VLSFVGVAAVISWIFSGTVPGWTSLTLLVVMISSVQLLVLGLIGEYVGRIYIQSKNRPLFMISQIHRRGRVPQLSTDRLP
ETESPPLNTLLAQSGPELRRSLREETSS

Sequences:

>Translated_348_residues
MFVSIVVPCYNEADGLREFHRRTTAAARALCGNRFELILVDDGSTDQTWPIINELLAEDRNVVAVKLARNHGHQLALTAG
LSTVRGDLVLVIDADLQDPPELLKPMYETMAREGADVVYGQRRSRAGETRFKTWSAEAFYRLLARITRVQIPVDTGDFRL
MSRRISDQLVQMPEHDRFIRGMVAWLGYKQVAFEYDREPRFAGSTKYPLLKMISFAADALISFSMVPLRIATYVGALLTT
VLSFVGVAAVISWIFSGTVPGWTSLTLLVVMISSVQLLVLGLIGEYVGRIYIQSKNRPLFMISQIHRRGRVPQLSTDRLP
ETESPPLNTLLAQSGPELRRSLREETSS
>Mature_348_residues
MFVSIVVPCYNEADGLREFHRRTTAAARALCGNRFELILVDDGSTDQTWPIINELLAEDRNVVAVKLARNHGHQLALTAG
LSTVRGDLVLVIDADLQDPPELLKPMYETMAREGADVVYGQRRSRAGETRFKTWSAEAFYRLLARITRVQIPVDTGDFRL
MSRRISDQLVQMPEHDRFIRGMVAWLGYKQVAFEYDREPRFAGSTKYPLLKMISFAADALISFSMVPLRIATYVGALLTT
VLSFVGVAAVISWIFSGTVPGWTSLTLLVVMISSVQLLVLGLIGEYVGRIYIQSKNRPLFMISQIHRRGRVPQLSTDRLP
ETESPPLNTLLAQSGPELRRSLREETSS

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=308, Percent_Identity=37.012987012987, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788588, Length=315, Percent_Identity=32.3809523809524, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787259, Length=93, Percent_Identity=34.4086021505376, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 39059; Mature: 39059

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVSIVVPCYNEADGLREFHRRTTAAARALCGNRFELILVDDGSTDQTWPIINELLAEDR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
NVVAVKLARNHGHQLALTAGLSTVRGDLVLVIDADLQDPPELLKPMYETMAREGADVVYG
CEEEEEEECCCCCEEEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHC
QRRSRAGETRFKTWSAEAFYRLLARITRVQIPVDTGDFRLMSRRISDQLVQMPEHDRFIR
CHHCCCCCCHHHCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
GMVAWLGYKQVAFEYDREPRFAGSTKYPLLKMISFAADALISFSMVPLRIATYVGALLTT
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSFVGVAAVISWIFSGTVPGWTSLTLLVVMISSVQLLVLGLIGEYVGRIYIQSKNRPLF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCH
MISQIHRRGRVPQLSTDRLPETESPPLNTLLAQSGPELRRSLREETSS
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MFVSIVVPCYNEADGLREFHRRTTAAARALCGNRFELILVDDGSTDQTWPIINELLAEDR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
NVVAVKLARNHGHQLALTAGLSTVRGDLVLVIDADLQDPPELLKPMYETMAREGADVVYG
CEEEEEEECCCCCEEEEECCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHC
QRRSRAGETRFKTWSAEAFYRLLARITRVQIPVDTGDFRLMSRRISDQLVQMPEHDRFIR
CHHCCCCCCHHHCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCHHHHHH
GMVAWLGYKQVAFEYDREPRFAGSTKYPLLKMISFAADALISFSMVPLRIATYVGALLTT
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLSFVGVAAVISWIFSGTVPGWTSLTLLVVMISSVQLLVLGLIGEYVGRIYIQSKNRPLF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCH
MISQIHRRGRVPQLSTDRLPETESPPLNTLLAQSGPELRRSLREETSS
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]