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The map label for this gene is infC [H]

Identifier: 146337304

GI number: 146337304

Start: 148620

End: 149222

Strand: Direct

Name: infC [H]

Synonym: BRADO0134

Alternate gene names: 146337304

Gene position: 148620-149222 (Clockwise)

Preceding gene: 146337302

Following gene: 146337306

Centisome position: 1.99

GC content: 60.2

Gene sequence:

>603_bases
TTGCCCGCAAAGGCATCTTCCTTCAAACTAGCCGCCTTCTTCCACAACCTTGGAGAACTACCCATTCGCCGCCCCAATCG
AGCCCCGCCCGCTGCCGTCAAAGACGGGCCGCGCACCAATGATGAGATTCGCAATGCGCAGATCCAGCTGATCGACGCCG
AAGGCACCAACCGTGGTGTCGTCGAGACCGTTGTCGCCATCAAGATGGCGGCCGAAGCAGGCATGGACCTGGTCGAGATT
TCGCCGAACAATTCGCCTCCCGTCTGCAAGATCATGGACTACGGGAAGTACAAATATTCGGCGCAGAAGAAGGCCGCCGA
GGCCCGCAAGAAGCAGAAGGTCGTCGAGATCAAGGAGATCAAGCTCCGTCCGATGATCGATGACCACGACTACGACGTGA
AGATGCGGGCGATGCAGCGCTTCTTCGAGGAGGGCGACAAGGTCAAGATCACCCTGCGCTATCGCGGCCGCGAAATGGCG
CACCAGGAGATCGGGACCAAGCTGCTCGACAAGGTGAAATCCGACGTGGCGGCGTTCGCCAAGGTCGAGCAGGACGCCAA
GTTCGAGGGCCGTCAGGTCGTCATGGTCCTGGCTCCGCGCTAG

Upstream 100 bases:

>100_bases
TCTCCTCGGGGGACGACGCCGTCACGCTGACATGCTGCGCGTGCGACGCAAGTGCCGCGGCGGCCGGGCGGAATTTCAAC
GCACCCGGGCCCGCGCGACC

Downstream 100 bases:

>100_bases
AGGCGCGAGGGACCACGCTTCAAACCGGGCCCGCCACGCGTTGGCGGGCTTTTCTCTTGAGGCGACGGACCACGGCCGTC
TTTTGGCCGGTGTCAGGACC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MPAKASSFKLAAFFHNLGELPIRRPNRAPPAAVKDGPRTNDEIRNAQIQLIDAEGTNRGVVETVVAIKMAAEAGMDLVEI
SPNNSPPVCKIMDYGKYKYSAQKKAAEARKKQKVVEIKEIKLRPMIDDHDYDVKMRAMQRFFEEGDKVKITLRYRGREMA
HQEIGTKLLDKVKSDVAAFAKVEQDAKFEGRQVVMVLAPR

Sequences:

>Translated_200_residues
MPAKASSFKLAAFFHNLGELPIRRPNRAPPAAVKDGPRTNDEIRNAQIQLIDAEGTNRGVVETVVAIKMAAEAGMDLVEI
SPNNSPPVCKIMDYGKYKYSAQKKAAEARKKQKVVEIKEIKLRPMIDDHDYDVKMRAMQRFFEEGDKVKITLRYRGREMA
HQEIGTKLLDKVKSDVAAFAKVEQDAKFEGRQVVMVLAPR
>Mature_199_residues
PAKASSFKLAAFFHNLGELPIRRPNRAPPAAVKDGPRTNDEIRNAQIQLIDAEGTNRGVVETVVAIKMAAEAGMDLVEIS
PNNSPPVCKIMDYGKYKYSAQKKAAEARKKQKVVEIKEIKLRPMIDDHDYDVKMRAMQRFFEEGDKVKITLRYRGREMAH
QEIGTKLLDKVKSDVAAFAKVEQDAKFEGRQVVMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=56.0975609756098, Blast_Score=176, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22526; Mature: 22395

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKASSFKLAAFFHNLGELPIRRPNRAPPAAVKDGPRTNDEIRNAQIQLIDAEGTNRGV
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCH
VETVVAIKMAAEAGMDLVEISPNNSPPVCKIMDYGKYKYSAQKKAAEARKKQKVVEIKEI
HHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHE
KLRPMIDDHDYDVKMRAMQRFFEEGDKVKITLRYRGREMAHQEIGTKLLDKVKSDVAAFA
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KVEQDAKFEGRQVVMVLAPR
HHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
PAKASSFKLAAFFHNLGELPIRRPNRAPPAAVKDGPRTNDEIRNAQIQLIDAEGTNRGV
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCH
VETVVAIKMAAEAGMDLVEISPNNSPPVCKIMDYGKYKYSAQKKAAEARKKQKVVEIKEI
HHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHE
KLRPMIDDHDYDVKMRAMQRFFEEGDKVKITLRYRGREMAHQEIGTKLLDKVKSDVAAFA
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KVEQDAKFEGRQVVMVLAPR
HHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]