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The map label for this gene is divL [H]

Identifier: 146337252

GI number: 146337252

Start: 89215

End: 91722

Strand: Direct

Name: divL [H]

Synonym: BRADO0079

Alternate gene names: 146337252

Gene position: 89215-91722 (Clockwise)

Preceding gene: 146337251

Following gene: 146337253

Centisome position: 1.2

GC content: 68.34

Gene sequence:

>2508_bases
ATGTCGGGCGTGATCGTGGTGATGCGTCAGACGCTGCTGTCATGCACGTCACTCGCGCGCAAGGGCCTGATGGGTCTCGC
TGCGACTGCGCTTGCGCCGGCAAGTCAGGGCTTCGCGGGCGATGGCGTGCCGGCGGATGCGATCTCTTCTCTTTTCGAGC
TGAGCCGGTCCGATGTCGCCGAGGTCACGGCGATGCTGGCGCTGCTCGGCTTCTCCGTGGTTGCTGCAATTGCTTTGGTG
CGCACGCGGCTTGCCGCTGCGCGGAAAGAGGCGCGACTGCGCGCCGACGTCGCGGAGCTGCAGCTGCAGGCCGACCGCTA
CCGCGCGTTGTTGTTCGCCGAACCGCAGATCCTGATCGCCTGGCCGGCCGGCGGTCACCGGCCACAGATCTCCGGCGACA
CATCCATGCTGGTACCGTCGGATCAGCCGCAGCGCATTCTCGCCTTCGGCAGCTGGCTGCCGCCGGAGCCGGCGCTGCAG
CTCGACCACGCCGTCGAGGCGCTGCGCGAGGCCGGCGAAGGCTTCATGCTCCACCTCACCACCTCGCACGGTCACGCCAT
CGAGGCGATGGGCCGCGCGATCGGCGGCCAGGCGATCGTGCGCATCCGCGAGCTGTCCGGTCTGCGCCGCGAGCTCGCCG
AGACGCAGCTGCGCTTCAAGGCGCTCGGCGAGGAGACGGAGTCGCTGCGCGCGCTCGCCTCCGCGCTGCCATGGCCGATC
TGGGCACGGCATGCCAACGGCGCGCTCGCTTACGTCAACGCCGCCTATGCCCGCGCCGCCGATGCGCGCGACATCCCCGA
CGCGATCAGCCGCAATCTCGAGCTGCTCGATTCCGCAGATCGGTCCGACCTGCAGCGTGCGCTCGGCGCCGGCGGACATT
TCGAGGGGCGGCTGCCGATCGTCATGGGCGGCGAGCGCCGGATGCATGACGTGCGGGCCTTCACGCTCGGCGGCGGCAGC
GCCGGCGTCGCCATCGATGCCAGCGAGGCTGCGGCGCTGACCGACGCGTTGGTGCGGATGCACGAGGCGCACCGCCGCAC
GCTCGACCAGTTGTCGTCGGGCGTCGCCGTGTTCGACGGCCAGCGCCGCCTCGCCTTCTACAACGACAGCTATCGCCGGC
TCTGGGATCTCGACACCGCGTTTCTCGACAGCCAGCCGGATGATTCCTCGGTGCTCGACCGCCTGCGCGCCTCGCGCAAG
CTGCCGGAGCAAGCCGACTTCCGAGCCTGGAAGGCCAAGCTGCACGAGGCCTATCGCGCGGTCGAGGCCGCCAAGGACAC
CTGGTTCCTGCCCGACGGCCGCGCGCTCTCCGTCGTCACCACGCCCAATCCGGAAGGCGGAGTCACCTATCTGTTCGACG
ACGTCACCGAGAGCTTTGCGCTGGCCCGCCGCTATGACGGCCTGATCCGGGTGCAGCGCGAGACGCTGGACAGCCTTGCC
GAAGGCGTCGCCGTGTTCGGCTCCAACGGCCGCGTCGAGCTGTTCAATCCGGCGTTTGCCAAGATGTGGCGGCTGTCGCC
AGACTCGCTGCGCGAGCATCCGCACATCGACACTGTCGAATCCTGGTGCCGGTCGATCTATGATGACAGCGTCGCCTGGC
GGACCATTCGCGAGGCGATCACCTCGATCGAGAACCGCCTCGACGTCGCGCTGAAGCTCGAGCGCAAGGACGGCAGCGTG
CTCGACTGCATGAGCCGGCCGCTGCCGGACGGCGCGACGATGCTGACCTTCCAGGACATCACCGACACCGAGAATGTCGA
GCGTGCGCTGCGCGAGAGCAACGAGGCGCTCGAAGCGGCCGGCCAGATGAAGATCGACTTCGTCCACCACGTCTCCTACG
AACTGCGTGCGCCGCTGACCACCATCATCGGCTTCGCGCATTTCCTGTCCGACCCGTCGACCGGGCCGCTGACGCCGAAG
CAGGCCGAGTATCTCGACTATGTCACCAAATCGACCAACGCGCTGCTGGCGCTGACCAACAACATTCTCGACCTCGCCAC
CATTGACGCCGGCGCGATGAAGCTCGAGCTCGGGCCCGTCGACGCCGCCAAGGCGATCGAGGCCGCGGCCGAGGGCGTGC
AGGACCGCCTCGCCACCGACCGCATCCGCCTCAGGGTCGAGGTCGCGCCCGATGTCGGCAGCTTCGTCGGCGACGAGCGC
CGCGTCGTCCAGGTGCTGTACAATCTGCTCGCCAATGCCGTCGGCTTCTCGCCGCAGGATTCGACCGTGATCGTGTCGGC
CCGCCGGACCGATCACAGCGTCGCCTTCGCGGTCACCGATTGCGGGCCAGGCATTCCGGCTGATATCAAGGACCAGATGT
TCGACTGGTTCGTCAGCCGCTCGCAAGGCTCGCGCCATCGCGGCGCCGGACTCGGCCTGTCGCTGGTGCGCTCCTTCGTC
GAGTTGCATGGCGGCAAGGTGCGGATGGATTCGGTGGTCGGCAAGGGCACCACGGTCACCTGTGACTTCCCGACCGACCA
CATCGCGCAACGCAACGCCGCGGAATGA

Upstream 100 bases:

>100_bases
ACCGCTGGAGTCCCGAAGCGGTTATTGTTGATTGATTCGTGGAACGGCGCGATCGGTGCGATCGGCGCCGCGCGGAACTT
TCGTGCGGTTTGGGGCAAAT

Downstream 100 bases:

>100_bases
CGGACCGACAGACATTCACGACCGCGCTGGCGGACGAGACCGCCACCGCCGCCTTGATGGCCGACCTCGCGCTGCTGATC
GGCCCGGGCGTGCTGATCAC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MSGVIVVMRQTLLSCTSLARKGLMGLAATALAPASQGFAGDGVPADAISSLFELSRSDVAEVTAMLALLGFSVVAAIALV
RTRLAAARKEARLRADVAELQLQADRYRALLFAEPQILIAWPAGGHRPQISGDTSMLVPSDQPQRILAFGSWLPPEPALQ
LDHAVEALREAGEGFMLHLTTSHGHAIEAMGRAIGGQAIVRIRELSGLRRELAETQLRFKALGEETESLRALASALPWPI
WARHANGALAYVNAAYARAADARDIPDAISRNLELLDSADRSDLQRALGAGGHFEGRLPIVMGGERRMHDVRAFTLGGGS
AGVAIDASEAAALTDALVRMHEAHRRTLDQLSSGVAVFDGQRRLAFYNDSYRRLWDLDTAFLDSQPDDSSVLDRLRASRK
LPEQADFRAWKAKLHEAYRAVEAAKDTWFLPDGRALSVVTTPNPEGGVTYLFDDVTESFALARRYDGLIRVQRETLDSLA
EGVAVFGSNGRVELFNPAFAKMWRLSPDSLREHPHIDTVESWCRSIYDDSVAWRTIREAITSIENRLDVALKLERKDGSV
LDCMSRPLPDGATMLTFQDITDTENVERALRESNEALEAAGQMKIDFVHHVSYELRAPLTTIIGFAHFLSDPSTGPLTPK
QAEYLDYVTKSTNALLALTNNILDLATIDAGAMKLELGPVDAAKAIEAAAEGVQDRLATDRIRLRVEVAPDVGSFVGDER
RVVQVLYNLLANAVGFSPQDSTVIVSARRTDHSVAFAVTDCGPGIPADIKDQMFDWFVSRSQGSRHRGAGLGLSLVRSFV
ELHGGKVRMDSVVGKGTTVTCDFPTDHIAQRNAAE

Sequences:

>Translated_835_residues
MSGVIVVMRQTLLSCTSLARKGLMGLAATALAPASQGFAGDGVPADAISSLFELSRSDVAEVTAMLALLGFSVVAAIALV
RTRLAAARKEARLRADVAELQLQADRYRALLFAEPQILIAWPAGGHRPQISGDTSMLVPSDQPQRILAFGSWLPPEPALQ
LDHAVEALREAGEGFMLHLTTSHGHAIEAMGRAIGGQAIVRIRELSGLRRELAETQLRFKALGEETESLRALASALPWPI
WARHANGALAYVNAAYARAADARDIPDAISRNLELLDSADRSDLQRALGAGGHFEGRLPIVMGGERRMHDVRAFTLGGGS
AGVAIDASEAAALTDALVRMHEAHRRTLDQLSSGVAVFDGQRRLAFYNDSYRRLWDLDTAFLDSQPDDSSVLDRLRASRK
LPEQADFRAWKAKLHEAYRAVEAAKDTWFLPDGRALSVVTTPNPEGGVTYLFDDVTESFALARRYDGLIRVQRETLDSLA
EGVAVFGSNGRVELFNPAFAKMWRLSPDSLREHPHIDTVESWCRSIYDDSVAWRTIREAITSIENRLDVALKLERKDGSV
LDCMSRPLPDGATMLTFQDITDTENVERALRESNEALEAAGQMKIDFVHHVSYELRAPLTTIIGFAHFLSDPSTGPLTPK
QAEYLDYVTKSTNALLALTNNILDLATIDAGAMKLELGPVDAAKAIEAAAEGVQDRLATDRIRLRVEVAPDVGSFVGDER
RVVQVLYNLLANAVGFSPQDSTVIVSARRTDHSVAFAVTDCGPGIPADIKDQMFDWFVSRSQGSRHRGAGLGLSLVRSFV
ELHGGKVRMDSVVGKGTTVTCDFPTDHIAQRNAAE
>Mature_834_residues
SGVIVVMRQTLLSCTSLARKGLMGLAATALAPASQGFAGDGVPADAISSLFELSRSDVAEVTAMLALLGFSVVAAIALVR
TRLAAARKEARLRADVAELQLQADRYRALLFAEPQILIAWPAGGHRPQISGDTSMLVPSDQPQRILAFGSWLPPEPALQL
DHAVEALREAGEGFMLHLTTSHGHAIEAMGRAIGGQAIVRIRELSGLRRELAETQLRFKALGEETESLRALASALPWPIW
ARHANGALAYVNAAYARAADARDIPDAISRNLELLDSADRSDLQRALGAGGHFEGRLPIVMGGERRMHDVRAFTLGGGSA
GVAIDASEAAALTDALVRMHEAHRRTLDQLSSGVAVFDGQRRLAFYNDSYRRLWDLDTAFLDSQPDDSSVLDRLRASRKL
PEQADFRAWKAKLHEAYRAVEAAKDTWFLPDGRALSVVTTPNPEGGVTYLFDDVTESFALARRYDGLIRVQRETLDSLAE
GVAVFGSNGRVELFNPAFAKMWRLSPDSLREHPHIDTVESWCRSIYDDSVAWRTIREAITSIENRLDVALKLERKDGSVL
DCMSRPLPDGATMLTFQDITDTENVERALRESNEALEAAGQMKIDFVHHVSYELRAPLTTIIGFAHFLSDPSTGPLTPKQ
AEYLDYVTKSTNALLALTNNILDLATIDAGAMKLELGPVDAAKAIEAAAEGVQDRLATDRIRLRVEVAPDVGSFVGDERR
VVQVLYNLLANAVGFSPQDSTVIVSARRTDHSVAFAVTDCGPGIPADIKDQMFDWFVSRSQGSRHRGAGLGLSLVRSFVE
LHGGKVRMDSVVGKGTTVTCDFPTDHIAQRNAAE

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=29.2887029288703, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1789149, Length=319, Percent_Identity=26.6457680250784, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=29.4339622641509, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788713, Length=305, Percent_Identity=27.5409836065574, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=32.6359832635983, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786600, Length=284, Percent_Identity=26.7605633802817, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.4930875576037, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790861, Length=261, Percent_Identity=27.2030651340996, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=210, Percent_Identity=29.0476190476191, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=25.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 90835; Mature: 90704

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVIVVMRQTLLSCTSLARKGLMGLAATALAPASQGFAGDGVPADAISSLFELSRSDVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EVTAMLALLGFSVVAAIALVRTRLAAARKEARLRADVAELQLQADRYRALLFAEPQILIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEE
WPAGGHRPQISGDTSMLVPSDQPQRILAFGSWLPPEPALQLDHAVEALREAGEGFMLHLT
ECCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TSHGHAIEAMGRAIGGQAIVRIRELSGLRRELAETQLRFKALGEETESLRALASALPWPI
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
WARHANGALAYVNAAYARAADARDIPDAISRNLELLDSADRSDLQRALGAGGHFEGRLPI
EEECCCCEEEEEHHHHHHCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHCCCCCCCCCCCE
VMGGERRMHDVRAFTLGGGSAGVAIDASEAAALTDALVRMHEAHRRTLDQLSSGVAVFDG
EECCCCHHHHEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
QRRLAFYNDSYRRLWDLDTAFLDSQPDDSSVLDRLRASRKLPEQADFRAWKAKLHEAYRA
CCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VEAAKDTWFLPDGRALSVVTTPNPEGGVTYLFDDVTESFALARRYDGLIRVQRETLDSLA
HHHCCCCEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVAVFGSNGRVELFNPAFAKMWRLSPDSLREHPHIDTVESWCRSIYDDSVAWRTIREAI
CCCEEECCCCCEEEECHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
TSIENRLDVALKLERKDGSVLDCMSRPLPDGATMLTFQDITDTENVERALRESNEALEAA
HHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
GQMKIDFVHHVSYELRAPLTTIIGFAHFLSDPSTGPLTPKQAEYLDYVTKSTNALLALTN
CCEEEEEHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
NILDLATIDAGAMKLELGPVDAAKAIEAAAEGVQDRLATDRIRLRVEVAPDVGSFVGDER
CCHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCHH
RVVQVLYNLLANAVGFSPQDSTVIVSARRTDHSVAFAVTDCGPGIPADIKDQMFDWFVSR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
SQGSRHRGAGLGLSLVRSFVELHGGKVRMDSVVGKGTTVTCDFPTDHIAQRNAAE
CCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHCCCCCEEEEECCHHHHHCCCCCC
>Mature Secondary Structure 
SGVIVVMRQTLLSCTSLARKGLMGLAATALAPASQGFAGDGVPADAISSLFELSRSDVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EVTAMLALLGFSVVAAIALVRTRLAAARKEARLRADVAELQLQADRYRALLFAEPQILIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEE
WPAGGHRPQISGDTSMLVPSDQPQRILAFGSWLPPEPALQLDHAVEALREAGEGFMLHLT
ECCCCCCCCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TSHGHAIEAMGRAIGGQAIVRIRELSGLRRELAETQLRFKALGEETESLRALASALPWPI
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
WARHANGALAYVNAAYARAADARDIPDAISRNLELLDSADRSDLQRALGAGGHFEGRLPI
EEECCCCEEEEEHHHHHHCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHCCCCCCCCCCCE
VMGGERRMHDVRAFTLGGGSAGVAIDASEAAALTDALVRMHEAHRRTLDQLSSGVAVFDG
EECCCCHHHHEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
QRRLAFYNDSYRRLWDLDTAFLDSQPDDSSVLDRLRASRKLPEQADFRAWKAKLHEAYRA
CCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VEAAKDTWFLPDGRALSVVTTPNPEGGVTYLFDDVTESFALARRYDGLIRVQRETLDSLA
HHHCCCCEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVAVFGSNGRVELFNPAFAKMWRLSPDSLREHPHIDTVESWCRSIYDDSVAWRTIREAI
CCCEEECCCCCEEEECHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
TSIENRLDVALKLERKDGSVLDCMSRPLPDGATMLTFQDITDTENVERALRESNEALEAA
HHHHHCCEEEEEEECCCCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
GQMKIDFVHHVSYELRAPLTTIIGFAHFLSDPSTGPLTPKQAEYLDYVTKSTNALLALTN
CCEEEEEHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
NILDLATIDAGAMKLELGPVDAAKAIEAAAEGVQDRLATDRIRLRVEVAPDVGSFVGDER
CCHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHCCHH
RVVQVLYNLLANAVGFSPQDSTVIVSARRTDHSVAFAVTDCGPGIPADIKDQMFDWFVSR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
SQGSRHRGAGLGLSLVRSFVELHGGKVRMDSVVGKGTTVTCDFPTDHIAQRNAAE
CCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHCCCCCEEEEECCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]