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The map label for this gene is ampH [C]

Identifier: 146337204

GI number: 146337204

Start: 35238

End: 36431

Strand: Direct

Name: ampH [C]

Synonym: BRADO0030

Alternate gene names: 146337204

Gene position: 35238-36431 (Clockwise)

Preceding gene: 146337201

Following gene: 146337206

Centisome position: 0.47

GC content: 66.33

Gene sequence:

>1194_bases
ATGCACAACAAGACCGACATCGATGGCGTGCTGCGTCAGAAGGCGGACGCACGCGAGATTCCAGGCGTCGTCGCCATCGC
GGCGGATAGCAAAGGCGTGATCTATGAGGGCGCCTTCGGCAAGCGCGACCTCGGCCGCGACGACGCCATGACCACCGACA
GCGTGTTCTGGATCGCCTCGATGACCAAGGCGATCACCTGCGCCGCCGGCATGCAGCTGGTCGAGCAGGGCACGCTGTCG
CTGGACGCGCCGATCGGCGATGTGCTGCCGGATCTCGCCGCGCCGAAGGTGCTCGACGGCTTCGACGCGAACGGCGAGCC
GATCCTACGTCCCGCGAAGACCGCGATCACGCTACGCCATCTCATGACCCACACCGCCGGCTTCTGCTACGACATGTGGA
ACGGCGACATGGCGGCCTATGTGCAGAAGGCCGGTACGCCCGGGATCATCACCTGCAAGAACGACGCGCTGAAGCTGCCG
TTGGCGTCCGATCCCGGCACGCGCTGGGAATATGGCATCAACATCGACTTCGTCGGCAAGGCGGTGGAGGCCGCGAGCGG
TCAGAAGTTGGATACATATCTGCGCGACAATCTGTTCGCGCCGCTCGGCATGGACGACACCGGCTTCAAGCTCGGCGCCT
CGCAGCGCGCGCGCCTCGTCGGGATGCATGCCCGCGGTGAGGATGGCAGCCTGGCGCCCATTCCGTTCGAGATCGAGCAG
GAGCCTGAATTCCATATGGGCGGGGGCGGCCTTTACGGCACGGCCGGCGACTACATCCGTTTCACCCGGATGATCCTCAA
CAACGGCCGGGGCAACGGCCACCAGGTGCTCAAGCCCGAGACCGTGGCGGCGATGCGCGACAATCACATCGGCGAGCTCG
AGATGACGAAGATGGCCGCCGCCGTGCCCGGCGTCACCAACGACGTCGACCTCTATCCCGACATCGTGAAGAAATGGGGC
CTGAGCTTCATGATCACGACGGCGCAGACCGCCGAGGGCCGTAGCGCCGGCAGCCTCGCCTGGGCCGGCCTCGCCAACAC
CTACTACTGGATCGACCCGGCGCGCGACGTCACCGGCGTGATCCTGATGCAGCTGTTGCCGTTCGCGGACCGGCTCTGTC
TTGAGACGTTCGCGGGCTTCGAGCGCGGCGTCTATGCCGGGCTGGACGCGGCCGGCGGCAAGAAGGCGGCGTGA

Upstream 100 bases:

>100_bases
ACGAGATCGCGACCACCTGCGTCCGCAGGGCGTCTTGCCGCCCGGATCGCCCCGGGGAACAATCGGGCACCGCCAGACAA
GAGCGGGACGGAGGAAACCC

Downstream 100 bases:

>100_bases
TGAGGTGAGGGGGTGCGGAGGCGATTGAGCGCGACGATCAAGCGTGTTCGATCGTCCAGCGATCCGAACTCATCAAAAGC
CTTGTTGGCGTACGACATGC

Product: putative beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MHNKTDIDGVLRQKADAREIPGVVAIAADSKGVIYEGAFGKRDLGRDDAMTTDSVFWIASMTKAITCAAGMQLVEQGTLS
LDAPIGDVLPDLAAPKVLDGFDANGEPILRPAKTAITLRHLMTHTAGFCYDMWNGDMAAYVQKAGTPGIITCKNDALKLP
LASDPGTRWEYGINIDFVGKAVEAASGQKLDTYLRDNLFAPLGMDDTGFKLGASQRARLVGMHARGEDGSLAPIPFEIEQ
EPEFHMGGGGLYGTAGDYIRFTRMILNNGRGNGHQVLKPETVAAMRDNHIGELEMTKMAAAVPGVTNDVDLYPDIVKKWG
LSFMITTAQTAEGRSAGSLAWAGLANTYYWIDPARDVTGVILMQLLPFADRLCLETFAGFERGVYAGLDAAGGKKAA

Sequences:

>Translated_397_residues
MHNKTDIDGVLRQKADAREIPGVVAIAADSKGVIYEGAFGKRDLGRDDAMTTDSVFWIASMTKAITCAAGMQLVEQGTLS
LDAPIGDVLPDLAAPKVLDGFDANGEPILRPAKTAITLRHLMTHTAGFCYDMWNGDMAAYVQKAGTPGIITCKNDALKLP
LASDPGTRWEYGINIDFVGKAVEAASGQKLDTYLRDNLFAPLGMDDTGFKLGASQRARLVGMHARGEDGSLAPIPFEIEQ
EPEFHMGGGGLYGTAGDYIRFTRMILNNGRGNGHQVLKPETVAAMRDNHIGELEMTKMAAAVPGVTNDVDLYPDIVKKWG
LSFMITTAQTAEGRSAGSLAWAGLANTYYWIDPARDVTGVILMQLLPFADRLCLETFAGFERGVYAGLDAAGGKKAA
>Mature_397_residues
MHNKTDIDGVLRQKADAREIPGVVAIAADSKGVIYEGAFGKRDLGRDDAMTTDSVFWIASMTKAITCAAGMQLVEQGTLS
LDAPIGDVLPDLAAPKVLDGFDANGEPILRPAKTAITLRHLMTHTAGFCYDMWNGDMAAYVQKAGTPGIITCKNDALKLP
LASDPGTRWEYGINIDFVGKAVEAASGQKLDTYLRDNLFAPLGMDDTGFKLGASQRARLVGMHARGEDGSLAPIPFEIEQ
EPEFHMGGGGLYGTAGDYIRFTRMILNNGRGNGHQVLKPETVAAMRDNHIGELEMTKMAAAVPGVTNDVDLYPDIVKKWG
LSFMITTAQTAEGRSAGSLAWAGLANTYYWIDPARDVTGVILMQLLPFADRLCLETFAGFERGVYAGLDAAGGKKAA

Specific function: Binds Penicillin And Contributes To The Normal Morphology Of Escherichia Coli. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI239747261, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI239752721, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI239741085, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17550934, Length=323, Percent_Identity=25.3869969040248, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=290, Percent_Identity=26.2068965517241, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 42510; Mature: 42510

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNKTDIDGVLRQKADAREIPGVVAIAADSKGVIYEGAFGKRDLGRDDAMTTDSVFWIAS
CCCCCCHHHHHHCCCCHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
MTKAITCAAGMQLVEQGTLSLDAPIGDVLPDLAAPKVLDGFDANGEPILRPAKTAITLRH
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHH
LMTHTAGFCYDMWNGDMAAYVQKAGTPGIITCKNDALKLPLASDPGTRWEYGINIDFVGK
HHHHHCCCEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEECCH
AVEAASGQKLDTYLRDNLFAPLGMDDTGFKLGASQRARLVGMHARGEDGSLAPIPFEIEQ
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCC
EPEFHMGGGGLYGTAGDYIRFTRMILNNGRGNGHQVLKPETVAAMRDNHIGELEMTKMAA
CCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCHHHHHHHH
AVPGVTNDVDLYPDIVKKWGLSFMITTAQTAEGRSAGSLAWAGLANTYYWIDPARDVTGV
HCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEHCCCCEEEEECCCHHHHHH
ILMQLLPFADRLCLETFAGFERGVYAGLDAAGGKKAA
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
>Mature Secondary Structure
MHNKTDIDGVLRQKADAREIPGVVAIAADSKGVIYEGAFGKRDLGRDDAMTTDSVFWIAS
CCCCCCHHHHHHCCCCHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
MTKAITCAAGMQLVEQGTLSLDAPIGDVLPDLAAPKVLDGFDANGEPILRPAKTAITLRH
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHH
LMTHTAGFCYDMWNGDMAAYVQKAGTPGIITCKNDALKLPLASDPGTRWEYGINIDFVGK
HHHHHCCCEEECCCCCHHHHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEEECCH
AVEAASGQKLDTYLRDNLFAPLGMDDTGFKLGASQRARLVGMHARGEDGSLAPIPFEIEQ
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCC
EPEFHMGGGGLYGTAGDYIRFTRMILNNGRGNGHQVLKPETVAAMRDNHIGELEMTKMAA
CCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCHHHHHHHH
AVPGVTNDVDLYPDIVKKWGLSFMITTAQTAEGRSAGSLAWAGLANTYYWIDPARDVTGV
HCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEHCCCCEEEEECCCHHHHHH
ILMQLLPFADRLCLETFAGFERGVYAGLDAAGGKKAA
HHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]