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The map label for this gene is lytS [H]

Identifier: 146302640

GI number: 146302640

Start: 5933555

End: 5934892

Strand: Reverse

Name: lytS [H]

Synonym: Fjoh_4913

Alternate gene names: 146302640

Gene position: 5934892-5933555 (Counterclockwise)

Preceding gene: 146302641

Following gene: 146302639

Centisome position: 97.34

GC content: 32.14

Gene sequence:

>1338_bases
ATGACTTTAAAACCAAATCTACTTAAGGCGTTGTTAGTAGGCGGAATCGTTTTTCTATTCTCCTTCCTGATTCGTTTTGC
TTCATTTGGAACAGCAATTTTCAACAATAACCTGTACATATTTTTCTTGTACTGTATGCTTTACAGTGTTGTGTTGTATA
TTGTAAATGCTTCTCTATTTGTGTATTTAGATAAGGTTTTTAAAGACAGCAGATTTTCTAATAAAAGAATTTTTATAGGT
TTTGTAAGTTCATTTGTTGTTTCGATTTTCGTTGTTTTTCTCCTTCGGGTTTTTACAAATGTAGTAATTGAAAGACGATC
TATTTTAAGTTTTCTGGCTAATGAAGAAGCTTCTACATATATAGAAAATGCGGTTATCGCTTTTATTATTCTGTTAGGAT
TTCATGCCTTACATTTTTACAAGGCATACCAGGAAAATAAAGTTATACAGCAAAAGATTATTGCGGGAACGGCAAATGCT
AAATTCGAAAGTTTAAAAAATCAAATCGACCCGCATTTTCTTTTTAACAGCTTAAATGTTCTAAGCTCTTTGATTGAAGA
AAACCCGGACAATGCGCAGCGGTTTACAACATCTTTATCTAAAATTTACAGATATGTTCTGGAACAGAAAGATAAAGAAC
TGGTATCTGTAGAAGATGAATTGTCGTTTGCAAAAACATATATGAATCTGCTTAAAATGCGTTTCGAAAACAGTTTGTTT
TATGAACTTCCAACAGAAAACATAAATCCTGATGCTAAAGTAGTGCCGTTGTCCTTACAGCTTTTGCTTGAGAATACAGT
GAAACACAATGTAGTGAGTGAACAAAAACCATTACATATTCGAATTTTTGTTGATAAAGATTATTTGGTTATACAAAATG
ATCTTCAGAAAAAAGAAGTTTTGCAGGATAGACAAGGTGTTGGACTGCAGAATATTGTAAATCGTTACGGAATTATAACC
GATAGGAAAGTGATGATTCAGCAGGATGAAAAAAACTTCTCCGTCAAAATTCCAATTTTAACTAAACAAATAACCGTCAT
GGATGTAAGTGCAGAATATAACGACGAAGCAAAAGCTTATTACAGAGCTAAAAAAAGAGTCGAAGAATTAAAAGGATTTT
ATGGAAATGTGATTTCATACTGTTGCGTAATTCCGTTTTTAGTGTTTATTAATTTAAGATTTTCACCGGGATTTCAATGG
TTTTGGTTTTCAGCTTTAGGCTGGGGATTTGGAGTAGCCATGCATGCTTTTAAAGTTTTTGGTTACAGTTCTGACTGGGA
AGAAAGAAAGATTAGAGAAATTCTGGAAAAAGAAAACAATCAAAAAAACTGGAAATAA

Upstream 100 bases:

>100_bases
TGCTACTTTTAAACCAGCTACTCCTTTTTCTCCAAAATGGGGATTAGACAGAGCTTTAGAAATCCAAAAAACTTGTAAAT
AATTTAATTCAAAAGAAATA

Downstream 100 bases:

>100_bases
TTATGGGACCTAATTATACAGAAGCAGAACGTTATTATCAGGCTCAAAAGAGAGTCAAGAAAATAAGAGAATTCTATGAG
CATTTAACAGTATATGTTTT

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTLKPNLLKALLVGGIVFLFSFLIRFASFGTAIFNNNLYIFFLYCMLYSVVLYIVNASLFVYLDKVFKDSRFSNKRIFIG
FVSSFVVSIFVVFLLRVFTNVVIERRSILSFLANEEASTYIENAVIAFIILLGFHALHFYKAYQENKVIQQKIIAGTANA
KFESLKNQIDPHFLFNSLNVLSSLIEENPDNAQRFTTSLSKIYRYVLEQKDKELVSVEDELSFAKTYMNLLKMRFENSLF
YELPTENINPDAKVVPLSLQLLLENTVKHNVVSEQKPLHIRIFVDKDYLVIQNDLQKKEVLQDRQGVGLQNIVNRYGIIT
DRKVMIQQDEKNFSVKIPILTKQITVMDVSAEYNDEAKAYYRAKKRVEELKGFYGNVISYCCVIPFLVFINLRFSPGFQW
FWFSALGWGFGVAMHAFKVFGYSSDWEERKIREILEKENNQKNWK

Sequences:

>Translated_445_residues
MTLKPNLLKALLVGGIVFLFSFLIRFASFGTAIFNNNLYIFFLYCMLYSVVLYIVNASLFVYLDKVFKDSRFSNKRIFIG
FVSSFVVSIFVVFLLRVFTNVVIERRSILSFLANEEASTYIENAVIAFIILLGFHALHFYKAYQENKVIQQKIIAGTANA
KFESLKNQIDPHFLFNSLNVLSSLIEENPDNAQRFTTSLSKIYRYVLEQKDKELVSVEDELSFAKTYMNLLKMRFENSLF
YELPTENINPDAKVVPLSLQLLLENTVKHNVVSEQKPLHIRIFVDKDYLVIQNDLQKKEVLQDRQGVGLQNIVNRYGIIT
DRKVMIQQDEKNFSVKIPILTKQITVMDVSAEYNDEAKAYYRAKKRVEELKGFYGNVISYCCVIPFLVFINLRFSPGFQW
FWFSALGWGFGVAMHAFKVFGYSSDWEERKIREILEKENNQKNWK
>Mature_444_residues
TLKPNLLKALLVGGIVFLFSFLIRFASFGTAIFNNNLYIFFLYCMLYSVVLYIVNASLFVYLDKVFKDSRFSNKRIFIGF
VSSFVVSIFVVFLLRVFTNVVIERRSILSFLANEEASTYIENAVIAFIILLGFHALHFYKAYQENKVIQQKIIAGTANAK
FESLKNQIDPHFLFNSLNVLSSLIEENPDNAQRFTTSLSKIYRYVLEQKDKELVSVEDELSFAKTYMNLLKMRFENSLFY
ELPTENINPDAKVVPLSLQLLLENTVKHNVVSEQKPLHIRIFVDKDYLVIQNDLQKKEVLQDRQGVGLQNIVNRYGIITD
RKVMIQQDEKNFSVKIPILTKQITVMDVSAEYNDEAKAYYRAKKRVEELKGFYGNVISYCCVIPFLVFINLRFSPGFQWF
WFSALGWGFGVAMHAFKVFGYSSDWEERKIREILEKENNQKNWK

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=114, Percent_Identity=36.8421052631579, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51863; Mature: 51732

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKPNLLKALLVGGIVFLFSFLIRFASFGTAIFNNNLYIFFLYCMLYSVVLYIVNASLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VYLDKVFKDSRFSNKRIFIGFVSSFVVSIFVVFLLRVFTNVVIERRSILSFLANEEASTY
HHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IENAVIAFIILLGFHALHFYKAYQENKVIQQKIIAGTANAKFESLKNQIDPHFLFNSLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
LSSLIEENPDNAQRFTTSLSKIYRYVLEQKDKELVSVEDELSFAKTYMNLLKMRFENSLF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YELPTENINPDAKVVPLSLQLLLENTVKHNVVSEQKPLHIRIFVDKDYLVIQNDLQKKEV
EECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCHHHHHHH
LQDRQGVGLQNIVNRYGIITDRKVMIQQDEKNFSVKIPILTKQITVMDVSAEYNDEAKAY
HHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCHHHHHH
YRAKKRVEELKGFYGNVISYCCVIPFLVFINLRFSPGFQWFWFSALGWGFGVAMHAFKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GYSSDWEERKIREILEKENNQKNWK
CCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLKPNLLKALLVGGIVFLFSFLIRFASFGTAIFNNNLYIFFLYCMLYSVVLYIVNASLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VYLDKVFKDSRFSNKRIFIGFVSSFVVSIFVVFLLRVFTNVVIERRSILSFLANEEASTY
HHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IENAVIAFIILLGFHALHFYKAYQENKVIQQKIIAGTANAKFESLKNQIDPHFLFNSLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
LSSLIEENPDNAQRFTTSLSKIYRYVLEQKDKELVSVEDELSFAKTYMNLLKMRFENSLF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YELPTENINPDAKVVPLSLQLLLENTVKHNVVSEQKPLHIRIFVDKDYLVIQNDLQKKEV
EECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCHHHHHHH
LQDRQGVGLQNIVNRYGIITDRKVMIQQDEKNFSVKIPILTKQITVMDVSAEYNDEAKAY
HHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCHHHHHH
YRAKKRVEELKGFYGNVISYCCVIPFLVFINLRFSPGFQWFWFSALGWGFGVAMHAFKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GYSSDWEERKIREILEKENNQKNWK
CCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]