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The map label for this gene is trpE [H]

Identifier: 146302617

GI number: 146302617

Start: 5912193

End: 5913644

Strand: Direct

Name: trpE [H]

Synonym: Fjoh_4890

Alternate gene names: 146302617

Gene position: 5912193-5913644 (Clockwise)

Preceding gene: 146302616

Following gene: 146302618

Centisome position: 96.97

GC content: 34.3

Gene sequence:

>1452_bases
TTGGCCGGAACTTTAACAGAAAAATATATTAAAACTAAAAAACAACATACATTGAAACCGTTTATACTCAACACACATTA
CAAACAAATTCTGGCAGATACCATTACGCCGGTTAGTATTTATTTTAAAATAAGAGATAAATTTCCAAATAGTTTATTGT
TGGAAAGCAGTGATTATCACGGAAACGACAACAGTTTCTCGTATATCTGCTGTAATCCTATTGCAACAATAAAAATTGAA
AACGAAACCATTTCAAAAACTTTTCCAGACGGAACTTCAGAGCAAAGTAAAATCGATGCTTCAACCAATATTCCAGAAGT
AATTCAGGAGTTTTCGAATCAATTTAAATCAGAAAAAAACGATTTTAAATTCATTAATAATGGTTTATTCGGATACATCT
CTTATGATGCTGTCCGCTACTTCGAAAAAGTTTCAATTGCCAAAAAAGACAATGCAACTTCAATTCCTGATGTATTTTAT
GCGGTTTACCAAAACATCATTGCGATTAATCACTTTAAAAATGAGGCTTATATTTTCTGTCACAGTGTTGACGGAAGAAA
TAACATTTCTGAAATCGAACAATTATTGCAGTCAAGAAATATCGCTTTATACAAATTCACTAAAGAAGGTGAAGGTTTCT
CTAACCTAACCGATGAAGAATTCAAACACAATGTAGCTTTAGCAAAAAAACACTGTTTTCGCGGCGACGTTTTTCAATTA
GTTTTATCACGTCGTTTTACACAAGATTTTAAAGGTGATGAATTTAATGTTTACAGAGCTTTACGAAGCATCAATCCGTC
TCCTTACCTATTCTTTTTTGATTATGGAGATTTCAAAATATTTGGTTCTTCACCCGAAGCACAAATTATTGTAAAAAACA
GAAAAGCAGAAATTCATCCAATCGCAGGAACTTTCAAAAGAACAGGAAATGACGAACGTGATGCGCTTTTAGCAAAAGAA
CTTTCTGAAGATAAAAAAGAAAACAGCGAACACGTAATGCTGGTAGATTTAGCCAGAAATGATTTAAGCCGCAACGGACA
TGATGTAAATGTAGAAAAATACAGAGAAGTTCAGTTTTTCTCTCATGTAATTCATTTAGTTTCAAAAGTTACAGGACACT
TACATGACAAAGCTACAACTATGCAGGTCGTTGCTGATACTTTCCCGGCAGGAACATTAAGCGGTGCGCCTAAACACAGA
GCGATGCAGTTGATTGAAGATTACGAAAAAACAAATCGTAATTTTTACGGAGGTGCAATTGGAGTAATGGATTTTGACGG
AAACTTTAACCACGCGATTATGATTCGAACTTTCCTTTCAAAAAATCATCAATTGCATTGCCAGGCTGGTGCCGGAATCG
TAGCCAGTTCTGACGAAGAAAGTGAAATGCAGGAAGTTTATAACAAATTAAGAGCCCTAAATACAGCGCTTGAAATGGCG
GAAAATATTTAG

Upstream 100 bases:

>100_bases
GTGGTGGAACAATTTACGTCAAACGTCGTGAACGAAGCTTCCTATGGTATTTTCAAAACTATAAATATAAAAGGCTTGTC
ATCACGACAAGCCTTTTTTT

Downstream 100 bases:

>100_bases
TCGCCAGTCGCGGTTTTCAGTCGCAGAACTTGAAACCTGAAACAATAAAAAAACAAACCATAAAAACCACAAACCATGAA
AAAAGCAGTATCAATTTTAG

Product: anthranilate synthase

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MAGTLTEKYIKTKKQHTLKPFILNTHYKQILADTITPVSIYFKIRDKFPNSLLLESSDYHGNDNSFSYICCNPIATIKIE
NETISKTFPDGTSEQSKIDASTNIPEVIQEFSNQFKSEKNDFKFINNGLFGYISYDAVRYFEKVSIAKKDNATSIPDVFY
AVYQNIIAINHFKNEAYIFCHSVDGRNNISEIEQLLQSRNIALYKFTKEGEGFSNLTDEEFKHNVALAKKHCFRGDVFQL
VLSRRFTQDFKGDEFNVYRALRSINPSPYLFFFDYGDFKIFGSSPEAQIIVKNRKAEIHPIAGTFKRTGNDERDALLAKE
LSEDKKENSEHVMLVDLARNDLSRNGHDVNVEKYREVQFFSHVIHLVSKVTGHLHDKATTMQVVADTFPAGTLSGAPKHR
AMQLIEDYEKTNRNFYGGAIGVMDFDGNFNHAIMIRTFLSKNHQLHCQAGAGIVASSDEESEMQEVYNKLRALNTALEMA
ENI

Sequences:

>Translated_483_residues
MAGTLTEKYIKTKKQHTLKPFILNTHYKQILADTITPVSIYFKIRDKFPNSLLLESSDYHGNDNSFSYICCNPIATIKIE
NETISKTFPDGTSEQSKIDASTNIPEVIQEFSNQFKSEKNDFKFINNGLFGYISYDAVRYFEKVSIAKKDNATSIPDVFY
AVYQNIIAINHFKNEAYIFCHSVDGRNNISEIEQLLQSRNIALYKFTKEGEGFSNLTDEEFKHNVALAKKHCFRGDVFQL
VLSRRFTQDFKGDEFNVYRALRSINPSPYLFFFDYGDFKIFGSSPEAQIIVKNRKAEIHPIAGTFKRTGNDERDALLAKE
LSEDKKENSEHVMLVDLARNDLSRNGHDVNVEKYREVQFFSHVIHLVSKVTGHLHDKATTMQVVADTFPAGTLSGAPKHR
AMQLIEDYEKTNRNFYGGAIGVMDFDGNFNHAIMIRTFLSKNHQLHCQAGAGIVASSDEESEMQEVYNKLRALNTALEMA
ENI
>Mature_482_residues
AGTLTEKYIKTKKQHTLKPFILNTHYKQILADTITPVSIYFKIRDKFPNSLLLESSDYHGNDNSFSYICCNPIATIKIEN
ETISKTFPDGTSEQSKIDASTNIPEVIQEFSNQFKSEKNDFKFINNGLFGYISYDAVRYFEKVSIAKKDNATSIPDVFYA
VYQNIIAINHFKNEAYIFCHSVDGRNNISEIEQLLQSRNIALYKFTKEGEGFSNLTDEEFKHNVALAKKHCFRGDVFQLV
LSRRFTQDFKGDEFNVYRALRSINPSPYLFFFDYGDFKIFGSSPEAQIIVKNRKAEIHPIAGTFKRTGNDERDALLAKEL
SEDKKENSEHVMLVDLARNDLSRNGHDVNVEKYREVQFFSHVIHLVSKVTGHLHDKATTMQVVADTFPAGTLSGAPKHRA
MQLIEDYEKTNRNFYGGAIGVMDFDGNFNHAIMIRTFLSKNHQLHCQAGAGIVASSDEESEMQEVYNKLRALNTALEMAE
NI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=470, Percent_Identity=29.5744680851064, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787518, Length=501, Percent_Identity=32.1357285429142, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1786809, Length=256, Percent_Identity=25.78125, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082077, Length=262, Percent_Identity=25.9541984732824, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=459, Percent_Identity=35.5119825708061, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6324361, Length=420, Percent_Identity=27.3809523809524, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 55122; Mature: 54990

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTLTEKYIKTKKQHTLKPFILNTHYKQILADTITPVSIYFKIRDKFPNSLLLESSDYH
CCCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCC
GNDNSFSYICCNPIATIKIENETISKTFPDGTSEQSKIDASTNIPEVIQEFSNQFKSEKN
CCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
DFKFINNGLFGYISYDAVRYFEKVSIAKKDNATSIPDVFYAVYQNIIAINHFKNEAYIFC
CCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEECCCEEEEE
HSVDGRNNISEIEQLLQSRNIALYKFTKEGEGFSNLTDEEFKHNVALAKKHCFRGDVFQL
ECCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VLSRRFTQDFKGDEFNVYRALRSINPSPYLFFFDYGDFKIFGSSPEAQIIVKNRKAEIHP
HHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCEEEEEECCCCEEEE
IAGTFKRTGNDERDALLAKELSEDKKENSEHVMLVDLARNDLSRNGHDVNVEKYREVQFF
CCHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCHHHHHHHHHH
SHVIHLVSKVTGHLHDKATTMQVVADTFPAGTLSGAPKHRAMQLIEDYEKTNRNFYGGAI
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
GVMDFDGNFNHAIMIRTFLSKNHQLHCQAGAGIVASSDEESEMQEVYNKLRALNTALEMA
EEEEECCCCCCEEEEEEHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
ENI
HCC
>Mature Secondary Structure 
AGTLTEKYIKTKKQHTLKPFILNTHYKQILADTITPVSIYFKIRDKFPNSLLLESSDYH
CCCHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCC
GNDNSFSYICCNPIATIKIENETISKTFPDGTSEQSKIDASTNIPEVIQEFSNQFKSEKN
CCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
DFKFINNGLFGYISYDAVRYFEKVSIAKKDNATSIPDVFYAVYQNIIAINHFKNEAYIFC
CCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEEECCCEEEEE
HSVDGRNNISEIEQLLQSRNIALYKFTKEGEGFSNLTDEEFKHNVALAKKHCFRGDVFQL
ECCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
VLSRRFTQDFKGDEFNVYRALRSINPSPYLFFFDYGDFKIFGSSPEAQIIVKNRKAEIHP
HHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCEEEEEECCCCEEEE
IAGTFKRTGNDERDALLAKELSEDKKENSEHVMLVDLARNDLSRNGHDVNVEKYREVQFF
CCHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCCCCHHHHHHHHHH
SHVIHLVSKVTGHLHDKATTMQVVADTFPAGTLSGAPKHRAMQLIEDYEKTNRNFYGGAI
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEE
GVMDFDGNFNHAIMIRTFLSKNHQLHCQAGAGIVASSDEESEMQEVYNKLRALNTALEMA
EEEEECCCCCCEEEEEEHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
ENI
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]